In this BizarroEpisode, the Griffins are the sole survivors of the apocalypse caused by the Y2K computer virus and head off to Natuck to rebuild society near a Twinkie factory.
* AfterTheEnd: The Setting.
* AllJustADream: The whole episode is revealed to be a dream of Pamela Ewing's, parodying ''Series/{{Dallas}}''.
--> '''Pamela Ewing''': Oh, Bobby, I just had the weirdest dream. I dreamt I saw the strangest episode of ''Family Guy'', and there was a giant chicken and Stewie was an octopus.\\
'''Bobby Ewing''': Hey, hey, hey. Come on, now. It's all right. Everything's going to be OK. ...What's ''Family Guy''?
* BaitAndSwitch: After being told all about [=Y2K=], Peter lets out a BigNo... because he saw the Trix Rabbit got a box of the cereal.
* BringIt: After the family leaves for Natuck, Joe (fused to his driveway) is approached by a giant rat. His response? "BRING IT ON!"
* DramaticIrony: After being kicked out of New Quahog, Peter apologizes, saying that people apparently didn't need guns, all of them unaware of what's transpiring in the gun-less town behind them.
* HazmatSuit: Peter has the family wear ones while hiding in the basement.
* IndestructibleEdible: Why the family seeks out the Twinkie factory, Peter claiming that they, along with cockroaches, are guaranteed to survive a nuclear holocaust.
* {{Irony}}: [[LampshadeHanging Lampshaded]] and [[DiscussedTrope discussed]] by two random guys when Octo-Stewies overrun the town [[AlwaysNeedWhatYouGaveUp after they get rid of the guns]].
-->'''Random guy:''' Hey Bob, you remember the other day you were asking me what the definition of irony was and I said-
-->'''Octo-Stewie latches onto his face'''
-->'''Random guy:''' AHHHH!
* ProperlyParanoid: After hearing about the [=Y2K=] rumor, Peter immediately builds a fallout shelter in the basement and forcibly barricades the family in it. Despite Lois's disbelief, TheEndOfTheWorldAsWeKnowIt ''does'' happen. Following that, Peter leads the family to Natuck where he believes that a Twinkie factory survived the apocalypse, and turned out to be right again. These instances lead Peter to believe that New Quahog needs guns and so cannibalizes the town's plumbing to fashion them, which unfortunately gets him and the others thrown out of the town. Despite the town's disbelief however, it turns out they ''do'' need the guns when Stewie's WeaponizedOffspring go on a rampage. Ironically, however, the Griffins are unaware of this and Peter says that he's ''not'' always right.
* ShoutOut:
** When the family first sees Peter in a hazmat suit, Chris screams that the government is here and tells [[ETTheExtraTerrestrial E.T.]] to run. We then see him do just that.
** "[[Film/{{Aliens}} Game over, man. Game over!]]"
* WeaponizedOffspring: The nuclear holocaust mutates Stewie into a half-human-half-octopus creature, who then lays a huge pile of eggs. Next scene, an army of human-octopi march through the town chanting "victory is ours", and attack the people by jumping at them and grabbing their faces with their tentacles.