* Wendy Oldbag attempts this on occasion in ''PhoenixWrightAceAttorney''. She's in her seventies, so it's not exactly successful. Its chief effect is to cause the most common target, Miles Edgeworth, to lose his composure and demand that it stop.
** Larry Butz also has them when doing his OcularGushers bit. It virtually never works.
** Phoenix Wright is said to have them too. Particularly effective when getting information out of the soft-hearted detective Gumshoe.
** Dahlia Hawthorne does this, and it ''does'' tend to work [[spoiler:until her true nature is revealed]].
** Her ex-boyfriend, Terry Fawles, does this in the courtroom lobby.
** Detective Gumshoe has a more subtle version of this as one of his default expressions, and [[TheWoobie it's arguably the most effective example in the game.]]
* There's a humorous subversion in ''ManaKhemiaAlchemistsOfAlrevis''. In one of Pamela's Character Quests, she enjoys making medicine ''that are actually dangerous to anyone who drinks it''. Problem is, all the victims (even ''[[TheQuietOne ROXIS]]''!), although they know of the med's effects, cannot refuse Pamela's offer to test them, because of Pamela's MoeMoe eyes.
** Another, more ironic example is ''[[CatGirl Nikki]]''.
** This seems to be Pamela's, er... weapon throughout ''AtelierSeries''. A far less dangerous example occurs in ''VideoGame/{{Atelier Iris 3|Grand Phantasm}}'', involving the quest for decorating the Grimoire Castle's library.
* In ''{{Banjo-Kazooie}}: Nuts and Bolts'', the titular pair does this in an attempt to have the [[DeusEstMachina Lord of Games]] give them their old powers from previous games back...it fails.
** He winds up giving them back in the end, however, in case Nuts & Bolts didn't sell well. Not surprisingly, it did, lampshaded by Mumbo in game no less.
-->'''Mumbo:''' Need to put floaters on boat, otherwise, boat sink like this game at retail.
* Your Mabari war hound in ''VideoGame/DragonAgeOrigins'' can do this to anyone. It even works on ''Morrigan''.
** Maybe they should have tried it against the darkspawn horde...
* Oddly enough, in ''VideoGame/DragonAgeII'', ''[[PerpetualFrowner Fenris]]'' of all people has a tendency towards this now and again, at least on a Hawke who's his friend; Merrill even namechecks the trope in a bit of party banter if Fenris is Hawke's love interest. It's remarkably effective, too...
** Merrill would know. She's a master of this herself.
* ''VideoGame/SamAndMaxSaveTheWorld'': Max tries to pull this off in "Abe Lincoln Must Die!" to get into the War Room, but fails.
* Mylune, a quest giver in ''VideoGame/WorldOfWarcraft'', says that she'll "give you the big eyes" if you don't save the fawns trapped in a burning forest.
* [[GenkiGirl Emi]] in ''KatawaShoujo'' is rather good at this. Even when Lilly has hardened [[HGamePOVCharacter Hisao]], he still falls for it when Emi pulls it.
* Ventus in ''VideoGame/KingdomHeartsBirthBySleep'' proves he knows how to do these when [[spoiler: he asks Terra and Aqua to kill him to prevent the X-blade from being formed.]]
* At one point in ''LittleBusters'', [[{{Kawaiiko}} Komari]] and [[{{Oneesama}} Kurugaya]] are fighting over what nickname Kurugaya should have. She claims that even if Komari calls her [[JapaneseHonorifics Yui-chan]] she'll just ignore her, and demonstrates. In response, Komari gives such a sad, tearful look that Kurugaya takes a significant amount of damage.
* ''Franchise/{{Pokemon}}'' introduces the move Baby-Doll Eyes, which [[ActionInitiative goes first regardless of speed]] and lowers the foe's attack.
* Clementine from ''Videogame/TheWalkingDead'' has the option of breaking these out to win over any survivor of the player's choice in season 2. Even when she's not ''intentionally'' doing it, she's still [[http://medias.gifboom.com/medias/t_a77cd0278d304aa0aea5748cf870d935.jpg adorable as can be.]]
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