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!! Animals
* Funnily enough, cats avert this in real life. If a cat ever opens its pupils really wide like Puss is in the page image, it means the cat is tense and/or excited ([[BlackEyesOfCrazy as in, just about to attack something -- possibly you]]). The cat's way of enticing a human to do something does not involve much direct eye contact at all -- they purr and rub their heads/bodies against you or nearby objects.
** That is, unless they simply meow/howl at you until you cave in just to shut the cat up. This is a common problem for owners of Siamese and other very vocal breeds.
** Unless you are this [[https://www.flickr.com/photos/artolog/2473548737/ fluffy kitten]].
* It's been suggested this is an evolutionary trait; humans are more likely to protect and feed dogs with this trope, therefore increasing their chances of survival, because a dog with PuppyDogEyes resembles a human baby, subconsciously activating our maternal and paternal instincts. In fact, wolves ''don't'' possess the ability to raise their eyebrows in this manner, and neither do huskies, the dog breed that is genetically closest to wolves. This strongly indicates that domesticated dogs faced evolutionary pressures to develop a slightly different facial structure to make them "cuter."
* A Russian experiment relating to breeding silver foxes based on tameness revealed the process of domestication tended to result in "cute" juvenile traits: multicolored coats, playfulness, floppy ears, and naturally large puppy eyes.
* Baby jumping spiders. Even an arachnophobe might look at [[http://static.fjcdn.com/large/pictures/01/d6/01d678_1383248.jpg this]] and go "d'awwww!"
** Jumping spiders in general have such PuppyDogEyes that Samsung was able to air an [[https://m.youtube.com/watch?v=G7YUK947LI8 effective and wholesome ad campaign]] their of Galaxy S22 Ultra mobile, with its mascot being a jumping spider falling in love with the phone thanks to its multiple lenses (in response to detractors claiming they were creepy and “spider-like”).

!! People
* Music/TheBeatles:
** Music/PaulMcCartney... though we are quickly moving into basset hound territory.
** Music/RingoStarr. These days he keeps them hidden behind a dark-lensed pair of glasses, but they were probably his most noticeable feature in the old days (well, besides the huge schnozz).
* Music/GarthBrooks and his enormous, soulful, bright blue eyes. He's particularly puppyish around wife Music/TrishaYearwood, with whom he is absolutely ''besotted'' -- when he looks at her he's basically the human incarnation of the Hearteyes Emoji, particularly if she's singing at the time.
* Music/DongBangShinKi's Jaejoong, who's known for his PuppyDogEyes. Can't really help it if he [[http://ic.pics.livejournal.com/nachan87/16699153/1080593/1080593_640.jpg looks]] [[https://dn3pm25xmtlyu.cloudfront.net/photos/large/591850280.jpg?1338726026&Expires=1429250263&Signature=A-reOXr2iUuDXiitZvh8vy9jrS0CzxAdYn0UcSEmrSZ5wk8vDX1CCeDxaZi7s-m0vnkJX0IT5UboNb45r9e3xXGAiA6Ksc4V~sXng2QVMO8JfZPn13deO5BP9HZbtE26iO3e6HPekqJWujVlwhNyKWaxNYNrQi1WGU7Si-smEUM_&Key-Pair-Id=APKAIYVGSUJFNRFZBBTA like]] [[http://media.tumblr.com/e027560a70ea999ac14c6dd717804f06/tumblr_inline_nh7qjaRpdS1sjcvgf.gif this]] on a daily basis.
* When people comment about Creator/JeffGoldblum's "odd" appearance, beyond his height (6'4½") they're usually consciously or unconsciously referring to the way his eyes are, as described by film critic/podcaster Steven Benedict in an episode discussing ''Film/TheFly1986'', naturally "slightly protruding" from his slender face. One reason that film served as his StarMakingRole was because his expressive eyes served so well as [[EyesNeverLie indications]] for his increasingly hideous character (in fact, one looks ''even larger'' [via a contact lens] in his final humanoid stage). During a 1987 ''[[Series/TheTonightShow Tonight Show]]'' interview, guest host/personal friend Creator/GarryShandling had Goldblum's co-star/girlfriend Creator/GeenaDavis sit down with them as well, and quipped:
-->See Jeff, you ''look'' in love...yeah, although you're looking at me, which is confusing! He has that, he has that look in his eyes, you know, like a dog gets when you save them from the Humane Society, that they just, you know...'Please take me home!' You know that look? That's what he has. You know, that kind of searching, distressed look.
* Dutch lib-dem politician Alexander Pechtold is known (and occasionally satirized in the media) for sporting these eyes. Some campaign posters from his own party will just show him [[http://www.newsframe.nl/wp-content/uploads/2012/09/D66_A3_poster.jpg staring directly at the viewer with his big eyes]].
* Music/SHINee's main vocal [[http://media.tumblr.com/tumblr_li8lmcvY2D1qcl8qx.jpg Jonghyun]] and their youngest [[http://data2.whicdn.com/images/30165111/large.jpg Taemin]] can give pretty good ones. Leader [[https://wanfitriah.files.wordpress.com/2014/09/onew__shinee__png__render__by_sellscarol-d5mjl56.png Onew]] could be added, but he's mostly described as a [[http://data3.whicdn.com/images/28999476/original.gif bunny]].
* Chinese actor Zhu Zan Jin (best-known as Jin Guangyao in ''Series/TheUntamed'') has [[https://static.tvtropes.org/pmwiki/pub/images/cql_jgy_4.png very]] [[https://static.tvtropes.org/pmwiki/pub/images/cql_jgy_2.png large]] [[https://pbs.twimg.com/media/EUd1YNxXkAAfs-X.jpg eyes]]. They're one of the reasons he's so popular among the series' fans, even those who hate the character he plays.
* Creator/PedroPascal and his live-action characters, such as [[Series/TheLastOfUs2023 Joel Miller]] and the bluntly-nicknamed "[[Series/TheMandalorian Brown Eyes]]", endear when he widens or glistens his eyes. In [[https://www.esquire.com/entertainment/tv/a43518988/pedro-pascal-the-last-of-us-interview-2023/ this]] ''Esquire'' article, the reporter can't help but notice how wistful or worried they look throughout the interview.
%%* [[Music/AliceInChains Layne Staley]] had [[http://fc02.deviantart.net/fs32/i/2008/189/a/4/Layne_Staley_2_by_shanijudd.jpg quite a pair]].
%%* Finnish musician [[http://40.media.tumblr.com/2fd11784568df0d4209f8752ea833b07/tumblr_mw1j67ampt1roqqono1_1280.png Jesper Anastasiadis]].
* Many women in the past invoked this on themselves by dripping sap of the [[http://en.wikipedia.org/wiki/Atropa_belladonna deadly nightshade]] into their eyes (this practice being the source of its scientific name), which caused the pupils to dilate and give this effect. Naturally, SideEffectsInclude ''very'' blurry sight, which they took in stride. Nowadays the extract (atropine) is still in use by doctors for aforementioned effect (i.e so they can inspect the pupil better) albeit in a way lowered dosage.
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