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[[caption-width-right:350:Keep in mind, he actually ''survived'' this.]]

* Hughes' HeroicBSOD after his belongings are confiscated by the government. He locks himself in a screening room, where he strips naked and succumbs to his OCD, lining up milk bottles full of urine and obsessively documenting his every action, both real and imagined.
* The XF-11 crash that nearly kills Hughes. He tries to aim for a nearby golf course, but the plane goes down over houses, sheering the roofs off, ripping a mansion to pieces and setting it on fire, smashing a power pole, and finally exploding. Quite frankly, it's a goddamn ''miracle'' Hughes survived, and that no one on the ground was killed.
** The aftermath as a broken-boned and bleeding Hughes desperately tries to get out of the burning wreckage. First, his leg is completely pinned to the warped and smashed interior of the plane. He breaks his own leg while pulling it free. Next, he tries to open the emergency hatch, but the glass is scalding hot from the fire, burning his hands severely. Hughes's skin sizzles, and he can be heard screaming in pain. He's forced to knock the hatch open with his back, which he manages to do, but is immediately set on fire when he gets outside the plane. Finally, his unimaginable agony comes to an end as a bystander puts out the flames on his back, and gets him to a hospital.
* "''Everybody'' works for ''you'', Howard..." Between John C. Reilly's expression and the breakdown that follows, it's downright Orwellian.
* The ending, as Howard stares at himself in the mirror and repeats "The way of the future...the way of the future...the way of the future."
** It's also a TearJerker, as Howard reminisces about his past while staring into the mirror and then looks back at himself, and sees what a shell of a person his mental illness has made him. TruthInTelevision - the real Howard Hughes would never fully recover from obsessive-compulsive disorder, and died a recluse.