* What Himuro saw when Yuri disappeared from 20th century Japan. He turns around, asks her where she wants to go for burgers, doesn't hear a reply, turns back around and -- GONE. It's not like she suddenly run off or--worst case scenario--was suddenly kidnapped. There's literally nowhere for her to go. The timing was far too quick. [[http://i5.mangareader.net/red-river/1/red-river-619145.jpg ''Her bag was still hitting the ground, for God's sake!!'']] What the hell did he tell her parents or the police?! What did he tell ''himself?''
** And what makes it worse is that [[DeclarationOfProtection Himuro just promised to protect her from whatever is bothering her.]] Then he lets go. And she's gone. [[AdultFear No matter what, that's psychologically destroying stuff.]]
* The horrible glazed expressions on the faces of whoever is under the effect of Black Water. It doesn't help that most of them (like Tito and Juda) spent all of their time up until their being BrainwashedAndCrazy as being sweet, kind, and friends with Yuri. It's doubly awful in the case of Tito, who goes within ''minutes'' from being a CheerfulChild who was one of Yuri's few friends and reminders of her home to bloodthirstily swinging a dagger at her.
* Similarily to the Black Water above, the effects of the Rose Water. Zannanza was a very court gentleman towards Yuri and kept his desires to himself, but him suddenly being rash and not above ''raping'' her is horrifying. No matter how much Yuri begs for him to wake up, he won't.
* The idea of Tito, and other people, being [[spoiler: ''skinned alive'']] is pretty terrifying.