* Index's HeroicSafeMode in the first arc, what with the CreepyMonotone and the general "something's freaking wrong with her" atmosphere.
* Touma [[spoiler: getting his right hand cut off]], and then just [[LaughingMad laughing insanely while bleeding everywhere.]]
* Particularly [[spoiler: during the time when Vento attacks Academy City and Aleister sends Hound Dog to retrieve Last Order.]]
* Shizuri Mugino after she [[spoiler:CameBackWrong.]] She gains[[spoiler:GlowingEyesOfDoom]] and her already [[{{Yandere}} freakishly]] [[AxCrazy crazy]] personality makes matters even worse. She even threatens to [[spoiler:burn off Rikou's virginity]]!
* The Agnese Forces [[spoiler:sticking pens into their own ears and bursting their eardrums all to just stop the main effect of [[BrownNote Index's current spell]].]] The casual ease with which they did it really reinforces the fanatic feel of the forces and makes the danger far more real when not even '''basic survival instinct''' can stop them.
* When Sister Lucia uses her "carriage wheel shrapnel attack" on Touma. The shrapnel ''embeds into Touma's arm, then rips itself out!''
* What happened to [[TeleportersAndTransporters Musujime Awaki]] when she messed up her calculations and found part of her leg [[TeleFrag stuck in a wall]], removing the leg also removed the leg's skin and '''muscle'''.
* New Testament 2: [[spoiler: When the Radiosonde Castle was finally brought down, the message left on it was for Touma. This ordinarily wouldn't be anything new, but the tone it set indicated they blamed him for what they lost in WWIII and ItsPersonal. The message, written messily in red spray paint: ''Welcome home, hero.'']]It's worse if you consider that [[spoiler: [[ThereIsNoKillLikeOverkill they destroyed mountains and rivers to track him down by rearranging the planet's leylines and nearly caused an Ice Age that would destroy humanity]]. And they did it ''casually '' just to track him. God's Right Seat wasn't that bad compared to them.]]
* The TomatoInTheMirror scene where [[spoiler: ''Hyouka Kazakiri's head breaks open.'']]
* New Testament 3: [[spoiler: Cendrillon, using magic based on "Literature/{{Cinderella}}", can remotely mutilate the feet of anyone who has feet of a different size than hers. Worse, Accelerator explains that if she had used it on him, he wouldn't have been able to block it. The spell ignores distance and obstacles to affect the target instantly, so there are no vectors for him to redirect.]]
* The various forms of BodyHorror GREMLIN inflicts on [[YouHaveFailedMe failed]] or [[YouHaveOutlivedYourUsefulness outlived]] henchmen.
* What happened to Misaka WORST, [[spoiler: being cut open.]]
* Marian Slingeneyer's [[BodyHorror human modification magic]] and [[AndIMustScream how she]] [[CruelAndUnusualDeath uses it]].
* Don't piss off a RealityWarper or he'll suspend you in the air and instantly remove all of the skin from your body. Complete with three close-ups: an arm, the beating heart, and the staring "face". Much worse in the novels, where the character's innards in mentioned scene explode across the room after WITH BLOOD VESSELS AND ORGANS STILL INTACT AND CONNECTED WITH EACH OTHER. Despite this, the person happens to be still alive. And let's not get into any of the sequences that include the clone of said RealityWarper, (thankfully) edited out of the anime adaption.
** Exclusive to the light novels: Aureolus Izzard [[spoiler: Made a copy of himself that had his memories and thought it was him. It goes crazy when it figures out the truth, and has the power to turn anything it hits with its dart into molten gold, even people.]]
* Accelerator. Pretty much anything he does while in violent mode, including [[spoiler: brutally killing 10,000 teenage girls, chewing on at least one of those girls' fingers, executing a team sent after him in the most traumatizing and MindRape -y ways possible.]] And then you factor in his Powers which make him more or less invincible. Unless you are stronger than a nuke or happen to have an ability that trumps his and he can't adapt to (so far, only Touma), he is essentially unkillable.
** Perhaps his most gruesome kills were made during the Invasion by Vento of the Front, when [[spoiler:Hound Dog kidnapped Last Order]]. [[https://www.youtube.com/watch?v=criARmG7wx4 This happens when they try to pursue him.]]
* New Testament 6: [[spoiler: Fraulein Kreutune has grown a monstrous mouth and is driven by instinct to try to eat Last Order's brains. Kakine Teitoku has come back, looking like a white zombie. He's also created an enormous army of copies of himself, as well as demonic rhinoceros beetles. [[FightingAShadow They are all him]].]]
* New Testament 7: [[spoiler: The Sixth Level 5, Etsu Aihana, is finally introduced. He's practically the [[BodyHorror creature]] from ''Film/TheThing1982'' in human form.]]