* ''WebComic/EerieCuties'': This is Ace's defining character trait and his AchillesHeel, which has often lead to [[ButtMonkey embarrassment]] and [[http://www.eeriecuties.com/strips-ec/let_me_make_this_up_to_you uncomfortable situations]], [[http://www.eeriecuties.com/strips-ec/inna_middle_of_something due to not wanting to hurt anyone's feelings.]]
* Lizard from the (discontinued) comics ''Living in Greytown'' and ''Lizard!''
* Bob from ''TheInexplicableAdventuresOfBob'' epitomizes this. He could be considered the ''weaponized'' version of this trope, because of his ability to [[TalkingTheMonsterToDeath talk his enemies into backing down.]]
* Merlitz from ''DanAndMabsFurryAdventures'' before he was PutOnABus. Doubled as the OnlySaneMan.
** Also from DMFA, [[http://missmab.com/Cast/matilda.php Matilda]]
* Danny Wilcox from the ''WalkyVerse'' is probably one of the best examples of this trope being played straight ever.
** ''And'' he gets his girl in the end. '''Woo Hoo!'''
** His ''DumbingOfAge'' [[AlternateUniverse variant]], on the other hand, is too neurotic and sarcastic to really be this.
* Dejoru of ''{{Juathuur}}'' seems is a really nice guy. But maybe it's just [[spoiler: a tactic to get laid.]]
* [[LovableNerd John Egbert]] of ''WebComic/{{Homestuck}}'' is definitely one of these. General consensus among his friends is that he's kind of a doofus, but that there's something endearing about his derpiness.
** Kanaya Maryam (aka grimAuxiliatrix) of the trolls is considered by many to be a [[NiceGuy Nice Girl]]. Polite, well-spoken and helpful; although she's a meddlesome meddler, she apparently does it only to help people. "Auxiliatrix" even means "a helpful woman". It remains to be seen if she has any ulterior motives, however.
*** Apparently her motive for watching out for [[KillerGameMaster Vriska]] all the time was [[DoggedNiceGuy not entirely]] [[LipstickLesbian altruistic.]]
*** Of course, Kanaya also comes with a massive case of BewareTheNiceOnes. Her WeaponOfChoice is a [[ChainsawGood CHAINSAW]], after all.
** Tavros Nitram also qualifies. One of the trolls notes that he seems to be ''unable'' to hate anyone. Which is ''really'' odd among trolls.
** The pre-Scratch trolls bring us Tavros's dancestor Rufioh, who's just too nice for his own good; Kanaya's dancestor Porrim, the EthicalSlut TeamMom; and, oddly enough, ''[[ChronicBackstabbingDisorder Vriska's]]'' dancestor, Aranea, who is almost faultlessly polite and forgiving, and whose main negative trait is that [[SesquipedalianLoquaciousness she likes to talk a bit too much]]. [[spoiler:although that seems to have changed as of recent updates...]]
* [[Webcomic/{{Mokepon}} Kahn Miles]] is probably the nicest Nice Guy you'll ever meet. He treats [[{{Jerkass}} Atticus]] with respect and kindness despite all the crap he gets from him, including saving his life, ''and'' he let Atticus [[spoiler: beat his already wounded pokemon]] because he knew it would make Atticus happy.
* [[TheAlcoholic Sedgewick]] from ''Webcomic/{{Lackadaisy}}'', whose only faults are his constant need to overwork, being [[ExtremeDoormat too polite]], and once killing a duck that still haunts him to this day. And with the reveal that one major character is about to die, the fandom has decided it has to him, because he's just too [[FanDarling likable]].
* Max of ''WebComic/{{Precocious}}'' is the lone nice guy in a class riddled with cognitive dissonance.
* Jeremy from ''PlatinumGrit''. He's so nice that he can be this and TheWoobie at the same time, because he's too damn nice to get down in the dumps about anything for long.
* Norway of ''WebComic/ScandinaviaAndTheWorld'', at least compared to [[DeadpanSnarker Sweden]] and [[EthicalSlut Denmark.]]
* In ''WebComic/{{Sinfest}}'', [[http://www.sinfest.net/view.php?date=2009-05-19 Slick tries to achieve this trope -- and fails.]]
* Elan, ''Webcomic/TheOrderOfTheStick'''s SpoonyBard, is ''definitely'' a Nice Guy. He's also fairly [[GoodIsDumb Dumb.]]
* Sam from ''SamAndFuzzy''. While he has aspects of BewareTheNiceOnes (most of whom end up getting subverted), at a whole he's the kindest and most inoffensive person in the strip -- excepting [[TheAce Carlyle]].
* The Virus from ExterminatusNow could be considered this, at least compared to his teammates.
* IN ''Webcomic/StickyDillyBuns'', Jerzy seems generally nice, and Andy does his best though he's a bit dim. But, proving that the status can be highly contextual, we also get Matt. In ''Webcomic/MenageA3'', Matt frequently takes the role of {{jerkass}} [[TheCasanova Casanova]], although his willingness to help his friends in any way that doesn't involve romantic monogamy establishes him as a JerkWithAHeartOfGold. But then he makes a guest appearance in the spinoff comic, where he encounters Ruby trying to pass as a man, evidently sees through the disguise when she starts panicking -- and [[http://www.stickydillybuns.com/strips-sdb/i_am_a_manly_man gracefully salvages some of her dignity]]. This makes him the first person in the entire comic to make a serious effort to reduce [[ButtMonkey Ruby's state of perpetual embarrassment]].
* ''VideoGame/{{Touhou}}'' often depicts Reimu Hakurei as an example of GoodIsNotNice, but in the fan comic ''Webcomic/TouhouJournal'', Reimu is depicted as a CuteMute with unconditional kindness, doing favors such as reading bedtime stories for Remilia (don't ask how she's able to do it), befriending a [[IJustWantToHaveFriends lonely]] Nue, and cheering up Marisa when she leaves a party in a troubled mood. When Aya, accompanied by Momiji, tries to sneak up on Reimu in an attempt to catch a scoop on Reimu having a darker, less-than-kind side, not only does Aya fail, but when Reimu spots them, her response is to ''cheerfully serve them tea!''
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