* ''WebComic/EerieCuties'': This is Ace's defining character trait and his AchillesHeel, which has often lead to [[ButtMonkey embarrassment]] and [[http://www.eeriecuties.com/strips-ec/let_me_make_this_up_to_you uncomfortable situations]], [[http://www.eeriecuties.com/strips-ec/inna_middle_of_something due to not wanting to hurt anyone's feelings.]]
* Lizard from the (discontinued) comics ''Living in Greytown'' and ''Lizard!''
* Bob from ''Webcomic/TheInexplicableAdventuresOfBob'' epitomizes this. He could be considered the ''weaponized'' version of this trope, because of his ability to [[TalkingTheMonsterToDeath talk his enemies into backing down.]]
* Merlitz from ''Webcomic/DanAndMabsFurryAdventures'' before he was PutOnABus. Doubled as the OnlySaneMan.
** Also from ''DMFA'', [[http://missmab.com/Cast/matilda.php Matilda]].
* Danny Wilcox from the ''Webcomic/WalkyVerse'' is probably one of the best examples of this trope being played straight ever.
** ''And'' he gets his girl in the end. '''Woo Hoo!'''
** His ''Webcomic/DumbingOfAge'' [[AlternateUniverse variant]], on the other hand, is too neurotic and sarcastic to really be this.
* Dejoru of ''Webcomic/{{Juathuur}}'' seems is a really nice guy. But maybe it's just [[spoiler: a tactic to get laid.]]
* [[LovableNerd John Egbert]] of ''WebComic/{{Homestuck}}'' is definitely one of these. General consensus among his friends is that he's kind of a doofus, but that there's something endearing about his derpiness.
** Kanaya Maryam (aka grimAuxiliatrix) of the trolls is considered by many to be a [[NiceGuy Nice Girl]]. Polite, well-spoken and helpful; although she's a meddlesome meddler, she apparently does it only to help people. "Auxiliatrix" even means "a helpful woman". It remains to be seen if she has any ulterior motives, however.
*** Apparently her motive for watching out for [[KillerGameMaster Vriska]] all the time was [[DoggedNiceGuy not entirely]] [[LipstickLesbian altruistic.]]
*** Of course, Kanaya also comes with a massive case of BewareTheNiceOnes. Her WeaponOfChoice is a [[ChainsawGood CHAINSAW]], after all.
** Tavros Nitram also qualifies. One of the trolls notes that he seems to be ''unable'' to hate anyone. Which is ''really'' odd among trolls.
** The pre-Scratch trolls bring us Tavros's dancestor Rufioh, who's just too nice for his own good; Kanaya's dancestor Porrim, the EthicalSlut TeamMom; and, oddly enough, ''[[ChronicBackstabbingDisorder Vriska's]]'' dancestor, Aranea, who is almost faultlessly polite and forgiving, and whose main negative trait is that [[SesquipedalianLoquaciousness she likes to talk a bit too much]]. [[spoiler:At first glance. Underneath everything and when it comes to making plans she turns out to be about just as bad, if not ''worse'', than Vriska]].
* [[Webcomic/{{Mokepon}} Kahn Miles]] is probably the nicest Nice Guy you'll ever meet. He treats [[{{Jerkass}} Atticus]] with respect and kindness despite all the crap he gets from him, including saving his life, ''and'' he let Atticus [[spoiler: beat his already wounded pokemon]] because he knew it would make Atticus happy.
* [[TheAlcoholic Sedgewick]] from ''Webcomic/{{Lackadaisy}}'', whose only faults are his constant need to overwork, being [[ExtremeDoormat too polite]], and once killing a duck that still haunts him to this day. And with the reveal that one major character is about to die, some of the fandom has decided it [[TooGoodForThisSinfulEarth has to him]], because he's just too [[FanDarling likable]].
%% * Max of ''WebComic/{{Precocious}}'' is the lone nice guy in a class riddled with cognitive dissonance.
* Jeremy from ''Webcomic/PlatinumGrit''. He's so nice that he can be this and TheWoobie at the same time, because he's too damn nice to get down in the dumps about anything for long.
* Norway of ''WebComic/ScandinaviaAndTheWorld'', at least compared to [[DeadpanSnarker Sweden]] and [[EthicalSlut Denmark.]]
* In ''WebComic/{{Sinfest}}'', [[http://www.sinfest.net/view.php?date=2009-05-19 Slick tries to achieve this trope -- and fails.]]
* Elan, ''Webcomic/TheOrderOfTheStick'''s SpoonyBard, is ''definitely'' a Nice Guy. He's also fairly [[GoodIsDumb Dumb.]]
* Sam from ''Webcomic/SamAndFuzzy''. While he has aspects of BewareTheNiceOnes (most of whom end up getting subverted), at a whole he's the kindest and most inoffensive person in the strip -- excepting [[TheAce Carlyle]].
* The Virus from ''Webcomic/ExterminatusNow'' could be considered this, at least compared to his teammates.
* IN ''Webcomic/StickyDillyBuns'', Jerzy seems generally nice, and Andy does his best though he's a bit dim. But, proving that the status can be highly contextual, we also get Matt. In ''Webcomic/MenageA3'', Matt frequently takes the role of {{jerkass}} [[TheCasanova Casanova]], although his willingness to help his friends in any way that doesn't involve romantic monogamy establishes him as a JerkWithAHeartOfGold. But then he makes a guest appearance in the spinoff comic, where he encounters Ruby trying to pass as a man, evidently sees through the disguise when she starts panicking -- and [[http://www.stickydillybuns.com/strips-sdb/i_am_a_manly_man gracefully salvages some of her dignity]]. This makes him the first person in the entire comic to make a serious effort to reduce [[ButtMonkey Ruby's state of perpetual embarrassment]].
* ''VideoGame/{{Touhou}}'' often depicts Reimu Hakurei as an example of GoodIsNotNice, but in the fan comic ''Webcomic/TouhouJournal'', Reimu is depicted as a CuteMute with unconditional kindness, doing favors such as reading bedtime stories for Remilia (don't ask how she's able to do it), befriending a [[IJustWantToHaveFriends lonely]] Nue, and cheering up Marisa when she leaves a party in a troubled mood. When Aya, accompanied by Momiji, tries to sneak up on Reimu in an attempt to catch a scoop on Reimu having a darker, less-than-kind side, not only does Aya fail, but when Reimu spots them, her response is to ''cheerfully serve them tea!''
* Tom of ''Webcomic/ElGoonishShive'' is the fake, manipulative version--in fact, he's too malicious to even count as a DoggedNiceGuy, he's just a straight-up ManipulativeBastard. Good Tom, however, is a parody due to being a perfect, genuine NiceGuy. He apologizes for getting offended for overhearing "Tom is a jackass" (they were talking about the other one), is appalled at the casual misogyny of a romantic comedy, and genuinely apologizes to his girlfriend for taking her there on a date, even though she doesn't care. Oh, and he may or may not have a superpower that lets him tell when random heroics are needed.
-->'''Good Tom:''' WAIT. ''A puppy is in danger.''\\
'''Tom's Girlfriend:''' Again?\\
'''Good Tom:''' ''Quickly!'' We must make haste! ''[runs off]''\\
'''Tom's Girlfriend:''' ''[following]'' You are the ''worst'' best boyfriend ever!
* ''Webcomic/TheStoryOfAnima'' has Kit Vulpes, a generally kind and compassionate kid [[http://tapastic.com/episode/88526 who doesn't even think twice]] [[http://tapastic.com/episode/89853 before launching to the rescue when someone's in danger]].