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[[quoteright:350:[[Anime/FullmetalAlchemist http://static.tvtropes.org/pmwiki/pub/images/comb14032016122219.jpg]]]]
[[caption-width-right:350:"You ''are'' foolish, all of you, even my own son."]]

->''"You asked what about me? It's simple. I love cutting up live people, and I like killing people so much, I can't stand it. I kill; therefore I am! I am who I am. That's all the evidence I need!"''
-->--'''Barry the Chopper''' (anime version only), "The Red Glow" (subtitles)

''Franchise/FullmetalAlchemist'' has several [[CompleteMonster especially heinous]] villains.

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[[foldercontrol]]

[[folder: [[Manga/Fullmetal Alchemist Original manga ]]
and ''Brotherhood'']]:

* [[MadScientist Shou Tucker]], the [[MadDoctor Sewing-Life Alchemist]], is known for his ability to create chimeras capable of speech. He's introduced to the Elric brothers as an awkward NiceGuy with a 4-year-old daughter named Nina. With his State Alchemist license soon to expire, Tucker created another Chimera by [[WouldHurtAChild fusing Nina and her dog Alexander]] into a miserable HalfHumanHybrid which is [[FateWorseThanDeath in constant agony]]. When the Elric brothers discovered Nina's new state, Edward's rage nearly drove him to kill Tucker. It is then revealed that the other speaking Chimera was actually his wife and Nina's mother, whom Tucker created by fusing her to another animal, earning him his State Alchemist status in the first place. Tucker [[ObliviouslyEvil refuses to admit what he did was horrible]], going as far as to tell the Elric brothers that they shouldn't have a problem with his actions and that anybody else would have done the same thing ForScience. While only appearing in one chapter, [[FourEyesZeroSoul Shou Tucker]] manages to be one of the most depraved characters in the manga and ''Brotherhood'' anime.
* [[BigBad Father]] is a [[EldritchAbomination being from beyond the Gate]] given form in a small flask and named Homunculus by the nameless slave who would become van Hohenheim in the Xerxes empire. Desiring to escape the flask, Homunculus would trick the king of Xerxes into a ritual that slaughtered multiple people to initiate an alchemy ritual that killed everyone in Xerxes and split their souls between Hohenheim and Homunculus, to the latter's horror. Later founding the nation of Amestris and creating the Homunculi, he took the name of "Father", guiding Amestris to become a military dictatorship that initiated military conflicts to provide bloodshed for an even greater ritual, including the genocide of the Ishvalan people. Intending to kill and steal the souls of tens of millions so that [[AGodAmI he could devour God]], or Truth itself, Father demonstrates cold sadism when he faces Hohenheim and [[TrulySingleParent his children again]], [[MindRape mentally torturing]] them as he also abandons or [[AbusiveParents tries to absorb his own Homunculi children]]. While he sees himself as an existence above humans, this is simply a reflection of Father's arrogance and pride, desiring to [[ImmortalityImmorality ascend ever higher, no matter who or what he has to destroy to gain ultimate knowledge and power]].
* The unnamed [[MadDoctor Doctor with the gold tooth]] created the homunculus Wrath by [[MadScientist inserting Philosopher's Stones into the bodies of thirteen candidates]], cackling when the process painfully killed the first twelve. Using the [[EmptyShell now-mindless]] bodies of the first dozen candidates, the Doctor unleashes them upon the heroes trying to stop Father from destroying Amestris. To force Mustang to open the Gate of Truth, the Doctor [[SlashedThroat slits the throat]] of his LoveInterest so she will bleed to death unless he opens it to save her. Knowing Father's plan would kill millions, the Doctor only strives to cause as much death as he can.
* ''[[Anime/FullMetalAlchemistTheSacredStarOfMilos The Sacred Star of Milos]]'': "Melvin Voyager", actually [[BigBad Security Chief Atlas]], is a [[AmbitionIsEvil power-hungry]], [[TheSociopath sociopathic]] Cretan soldier, who starts off by denouncing his vows to protect the Crichton family by brutally murdering the female protagonist Julia's parents and then [[FaceStealer rips the skin of Julia's brother's Ashleigh's face]] in order to steal his identity. This was done so that Atlas could easily [[ManipulativeBastard manipulate the rebel group, Bats]], into making a transmutation circle for him by promising Creta enough power to rival other nations. Ashleigh, in turn, ended up becoming a vengeful KnightTemplar, seeking revenge for Milos after losing his faith for its people. After showing his true colors, Atlas murders Bats' leader, Miranda, so that he can use her blood to activate the circle. He then proceeds to [[ChronicBackstabbingDisorder murder his co-conspirator, Raul, as well]] when it turns out there is not enough sacrificial blood. After succeeding in activating the circle, Atlas sacrifices dozens of Amestrian soldiers by feeding them to Milos's machinery to create a PhilosophersStone for himself. A textbook sociopath who abandoned his honor and home country for power, Atlas stood out as one of the most vile villains in the ''Brotherhood'' canon.

[[/folder]]

[[folder: [[Anime/Fullmetal Alchemist 2003 Anime ]]
]]:

* [[BigBad Dante]] is a 400-year-old woman who [[ImmortalityImmorality keeps herself alive]] by trading her soul with a younger person, then killing her old body, repeating the process indefinitely. When Dante's own Philosopher's Stone runs out, she sets in motion a plan to cause so much misery in Amestris that someone will be desperate enough to recreate the Stone, allowing her to steal it with no risk to herself. {{Abusive|Parents}} towards her Homunculi "children", Dante arranges for Ed to kill Greed. Stealing the body of her assistant, Dante later tries to move into the body of one of Ed's {{Love Interest}}s when her current body begins to deteriorate. Said action is made even more disgusting by the fact Ed is both a teenager and the son of Dante's own ex-lover. When Gluttony falls into despair because of Lust's death, Dante, annoyed with him being unwilling to follow orders, callously destroys his mind to make him easier to control.
* This version of [[MisanthropeSupreme Envy]] is an AxCrazy sadist, who uses his powers to torment his victims by [[KickTheDog taking on the forms of people's loved ones]] before killing them. He is responsible for murdering Maes Hughes, by impersonating his wife and rubbing it at his face before killing him. Envy is mostly seen [[ManipulativeBastard manipulating Amestris's government behind the scenes]] with a string of mind games and murders. This all culminates in him killing Ed when he finds out that Envy is, in fact, the homunculus version of his half-sibling. Unlike other homunculi, who wanted to become humans, Envy was the sole exception, only [[PsychoForHire working for Dante so he could kill as many people as possible]], abusing both other homunculi and prisoners in the process simply for laughs. When captured by the Thule Society in his serpent form, Envy is kept docile by being allowed to painfully impale his father Hoenheim, with his fangs.
* [[PresidentEvil King Bradley]]/Pride is [[TheGeneralissimo the military dictator]] of Amestris and one of [[BigBad Dante's]] most trusted homunculi. He is the mastermind behind the events that caused the [[FinalSolution genocide in Ishbal]], and worse yet, repeats the same actions in Reole in order to lead his own nation in destruction. At one point, he even releases infamous MadBomber [[AxCrazy Solf J. Kimblee]] from prison and unleashes him upon Reole citizens in order to take care of the deed as fast as possible. While mainly assisting Dante in her plans to create the PhilosophersStone all over again, it is made clear that Bradley enjoys committing these deeds for the sake of [[MasterRace "purifying" the population]] and expanding the country's territory. After Martel finds out about [[TheReveal Bradley's true identity]], he proceeds to [[MoralEventHorizon murder her cold-bloodedly in front of Al]] in order to keep her silent. It is not until the final arc of the series when Bradley reaches the level of an irredeemable monster, when he plays a sadistic cat-and-mouse game with Roy Mustang, torturing him both physically and emotionally, even bringing up the tragic fact that he couldn't save his best friend from a certain death. When his [[MoralityPet own son]] steps in the hopes of helping his father, Bradley [[OffingTheOffspring strangles him to death]] while ranting about being an agent of God.
* [[MadBomber Solf J. Kimblee]] stands out as [[CharacterExaggeration even more insane]] and [[AxCrazy psychotic]] than his [[BlueAndOrangeMorality manga counterpart]]. A [[PsychoForHire state alchemist]] with the ability to turn [[StuffBlowingUp objects]]—and [[WhyAmITicking people]]--- into explosives, Kimblee LovesTheSoundOfScreaming and earned a reputation during the Ishbal genocide for his ruthlessness. As seen in early flashbacks, Kimblee was responsible for massive explosions all around the region, all while laughing about it. He also tortured Scar by sadistically blasting him apart one piece at a time, making him the distinctive mark in his forehead. Later, Kimblee escapes the prison by using a fellow inmate as a bomb and starts working for Greed before betraying him to Frank Archer and being indirectly responsible for the Devil's Nest massacre. After his reinstatement, Kimblee reenacts the Ishbal genocide in Reole and tries to murder Al by transforming him into a walking time bomb. When encountered by Scar, Kimblee reveals that he has no reason for fighting, other than the fact that he sees [[MisanthropeSupreme humans—not exempting himself--as empty beings]] and that [[{{Sadist}} he simply enjoys seeing people suffer]].
* The anime incarnation of [[AxCrazy Barry the Chopper]] is [[AdaptationalVillainy far more vicious and horrifying]] than his original. He was once a simple butcher living in Central City, but when he grew bored of chopping up animals, decided to butcher his wife and found he loved the sensation and followed by [[SerialKiller gruesomely murdering many young women]]. Barry's killing spree came to a temporary halt when he was arrested after trying to kill the Elrics' childhood friend, Winry. Rather than be executed, Barry was experimented on, had his soul bound to a suit of armor, and was used as a guardian for the Fifth Laboratory. After it was destroyed, Barry slaked his bloodlust by [[PsychoForHire joining a group of mercenaries]] to slaughter a camp of harmless Ishvalans.
* ''[[Anime/FullmetalAlchemistTheConquerorOfShamballa The Conqueror of Shamballa]]'': [[KnightTemplar Thule Society Chairman Dietlinde Eckhart]] is the BigBad and an [[{{Ghostapo}} occult supporter of the Nazi party]] trying to reach the titular Shamballa to gain the power to conquer the world. Capturing Envy to open the gate to the other world, Eckhart keeps the homunculus docile by allowing him to bite into Hoenheim, leaving the man in agony. When Hoenheim sacrifices himself to open the gate, Eckhart, no longer needing Ed's alchemy, shoots him and leads an assault into his world. Enthralled with her newfound ability to use alchemy but fearing others with the same power, Eckhart tries to [[OmnicidalManiac destroy the very world]] she once sought to conquer, a [[AbsoluteXenophobe xenophobic]] hypocrite who would not tolerate anyone but herself having authority.

[[/folder]]

[[folder: [[Film/Fullmetal Alchemist 2017 2017/ 2018 Live-Action Film ]]
]]
* [[MadScientist Sho(u) Tucker]], the [[MadDoctor Sewing-Life Alchemist]], is revealed to have fused his own wife with a dog to turn her into a chimera, a twisted parody of life that [[AndIMustScream suffers in perpetual pain]]. Later performing the same treatment with his own daughter, Tucker defends his actions by claiming it is completely natural to perform unethical experiments solely on the basis of being able to. Being beaten and imprisoned by Edward Elric, Tucker later joins a military coup where he helps to create countless Mannequin Soldiers to unleash upon the civilian populace solely to spite Ed, without a single care for the lives that will be lost.
* [[InsaneAdmiral General Hakuro]] is a ruthless military officer seeking a military coup. Manipulating conflict, death and murder across Amestris, Hakuro recruits Tucker and reveals the truth of the {{Philosophers Stone}}s as the amalgam of fused human souls and lives, flashbacks showing that Hakuro had [[PlayingWithSyringes thousands of prisoners and innocents painfully melted down]] to create thousands and thousands of stones. Upon confronting Edward, Hakuro plans to unleash the cannibalistic Mannequin Soldiers on Amestris to kill until Hakuro can seize control of the country, driven by nothing but a hunger for power.
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