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InAWorld where humans are not the only beings, there exists a race known as demihumans. At the height of the golden age of genetic engineering, that race was created by humans [[SlaveRace to serve them]].

As time passed, the demihumans began questioning why they served their creators. At the end of the last century, a war broke out between the East and the South, so demihumans escaped their slavery and equality was established. However, the gap between the races has not been bridged. Demihumans still struggle with discrimination, live in the slums and face the fear of being sold to slavery every day.

Canon Passacagilia, a child of a human and a demihuman, is an officer of the East Side's Police Bureau's Special Second Division who are in charge of dealing with crimes related to demihumans. She patrols the city's streets helping humans and demihumans alike. Along with Johan Bachenbell, a man raised in an orphanage for both humans and demihumans, her goal is to help the races live alongside one another in peace.

''Megalomania'' is a {{shounen}} manga written and drawn by Daisuke Hiyama. It was serialized in ''Creator/SquareEnix'''s Gangan Comics magazine from 2007 to 2009, and compiled into four volumes. The story mixes SciFi and comedy elements in an UrbanFantasy setting.

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!This manga provides examples of:
* AtopAMountainOfCorpses / FieldOfBlades: One of the chief's flashbacks involving Kamaitachi combines these.
* AxCrazy: George Antheil. While Kamaitachi have a natural urge to cutting things, he's so off the rails he keeps looking for a woman he ''can keep cutting without her dying.'' He becomes obssessed with Canon because of that.
* BadassNormal: Bachenbell, A trained cop who is not afraid to fight dirty or go against several armed opponents alone.
* BadassAdorable: Canon, almost looks too cute to be a cop until she puts on her GameFace.
* CrystalDragonJesus: The Haptemis faith.
* DarkAndTroubledPast: Canon. Being a half-breed caused her to be shunned by humans and demihumans alike.
* DestructiveSaviour: Canon is one but this results in most humans [[DeconstructedTrope either fearing or shunning her]].
* FantasticGhetto: The demihuman slums.
* FantasticRacism: A big part of the story and set-up is that demihumans are discriminated against by humans.
* FacelessGoons: Subverted by the Special first branch which seem to be good guys at first but have no issues killing criminal demihumans, just because they are not human.
* GameFace: Canon has a pretty mean one when she transforms.
* HalfBreedDiscrimination: Canon struggles with this, as both races tend to look down on her for her mixed lineage. This is also one of the reasons she tries to mend the divide between the races.
* HalfHumanHybrid: Canon is the child of a human and a demihuman, giving her a demihuman appearance and super powers when she wants to fight for real.
* HumanoidAbomination: Some of the scarier looking demi-humans are this.
** Canon in "demon" mode.
* MysteriousPast: Johan has one related to his history with the first division.
* PintsizedPowerhouse: Canon is barely as tall as Johan's shoulder, but she had no trouble beating a gargantuan demihuman giant who was incredibly violent due to experiencing withdrawal. Her demihuman powers helped.
* ServantRace: The demihumans were created to be this but were treated more like slaves.
* {{Youkai}}: The demihumans are basically separated into breeds that are youkai.
** Merry is an Izuna, a breed likely based on [[AsianFoxSpirit Kitsune]].
** Earl Little's female cohort is a nekomata who turns into a black cat.
** George Antheil is part of the Kamaitaichi.
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