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[[quoteright:350:[[Comicbook/IVampire http://static.tvtropes.org/pmwiki/pub/images/IVampireEdited_3553.jpg]]]]

The oldest vampire movie/character plot in the book: the protagonist is infected with TheVirus and undergoes the ViralTransformation into a vampire or some other monstrous entity like a [[WolfMan werewolf]] or zombie. They have only a short time until the {{curse}}s of the FaceMonsterTurn asserts itself and the overwhelming thirst to [[ImAHumanitarian eat, drink and transform their fellow man]] is all they know.

Before the clock runs out, they will do everything in their power to [[FindTheCure find]]... ''(MelodramaticPause!)''... [[AscendedDemon a cure]], use HeroicWillpower to kick ass and bring [[RoaringRampageOfRevenge a world of hurt]] down on the entire race of monsters that infected them... all the while using HeroicResolve to [[WarmBloodbagsAreEverywhere resist those warm bloodbags everywhere]].

This is OlderThanTelevision, going back to Mina Harker in ''{{Literature/Dracula}}'' itself. It may use NoOntologicalInertia to solve the problem by killing the head vampire, but more modern movies will use outright biological rather than mystical cures for the [[OurVampiresAreDifferent virus-based vampires]].

[[{{Pun}} These nights]], this trope has extended to just about any [[TheVirus infectious]] [[OurMonstersAreDifferent monster]], a few other BodyHorror [[EmergencyTransformation transformations]], and even outright {{curse}}s. Expect the hero to gain an advantage from [[OneHeroHoldTheWeaksauce lacking the traditional weaknesses of their breed]] and discovering they can tap into HeroicWillpower to get a powerup to beat their sire. This last bit can get a bit silly, as the hero-now-monster is usually [[HorrorHunger starving]] by this point from fasting on blood.

On the bright side, since UndeathAlwaysEnds the Vampire Refugee won't stay such for long... though whether it's because of death or a cure varies.

Compare PhlebotinumRebel, MonstersAnonymous, and AndThenJohnWasAZombie. Contrast TranshumanTreachery. See also StagesOfMonsterGrief. SubTrope to ProHumanTranshuman.

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!!Examples:

[[foldercontrol]]

[[folder: Anime and Manga]]
* This is the main premise of the first ''LightNovel/VampireHunterD'' movie and novel, with the heroine hiring D to help her, complicated by the fact that her entire town is not only aware of the danger a Vampire Refugee can pose but actively on the lookout for them.
** But subverted in the second movie. Although D and the Borghoff Brothers assume she's been carried off against her will, Charlotte Ellborne actually [[spoiler: wants Meir Link to transform her into a vampire in order to facilitate their love affair]]. Especially interesting because [[spoiler: Carmilla seems to view their relationship as a way of fostering better relations between vampires and humans]] .
** Well, that's what she claims. [[spoiler:In actuality Carmilla is brutal and bloodthirsty even by vampire standards, and only cares for humans for their blood. The whole purpose of her involvement in the enterprise was to resurrect herself with Charlotte's blood. Meir (Myer?) of course wasn't aware of this]].
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[[folder:Comic Books]]
* Hannibal King in the MarvelUniverse.
* The comic ''[[ThirtyDaysOfNight 30 Days Of Night]]'' had the [[spoiler: sheriff injecting himself with vampire blood to become a "Good Vampire" (barely controls it and he kills himself shortly after)]] to beat the bad guys.
* Andrew Bennett from ''ComicBook/HouseOfMystery'''s "I... Vampire" series straddled the line between this trope and DoomedMoralVictor. Though he did jump at the opportunity for a cure when he chanced upon one, for most of his unlife Bennett harbored no hope of restoring himself, and was preoccupied with exterminating a bloodline of evil vampires he'd mistakenly sired, by converting his onetime lover. To survive, he bought blood by the bottle from street people.
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[[folder: Film]]
* ''Film/HorrorOfDracula'' has Harker, who in this version [[spoiler:is actually turned into a vampire. Helsing grimly has to stake him.]]
* ''Rise: Blood Hunter'': Though Sadie is very determined to get revenge for her unwilling (and unplanned) vampirisation on the bloodsuckers of L.A., she slips when it comes to feeding on a poor schlub offering her a lift.
* The Star/Laddie subplot of ''TheLostBoys''. "YOU TRIED TO MAKE ME A KILLER!"
* ''Film/TheFly'' (the remake) has doctor Brundle try to reverse the onset of the creature he's becoming. [[FateWorseThanDeath He fails]].
** The sequel with his son does get to stay human though. Albeit by dumping the fly genes into the CorruptCorporateExecutive, making him [[FateWorseThanDeath a mutant slug]], [[LaserGuidedKarma kept alive for study in a dark pit]].
* The first ''{{Blade}}'' movie had the vampire antidote for the GirlOfTheWeek. Interestingly, it seems this cure sticks around, and at least two more characters get cured of vampirism in the sequels.
** However, it can't cure the eponymous character of vampirism without taking away his nifty powers (he just uses a serum to suppress his vampiric bloodlust), nor can it cure anybody who was born a vampire. It can only cure vampirism if one contracts it via a bite.
* ''{{Film/Ultraviolet}}''.
** Incidentally, it seems that the girl became much more bloodthirsty (or downright sadistic) after the cure was applied.
* Nick from ''TheForsaken''. It is heavily implied in the movie that ''all'' [[WhoYouGonnaCall vampire hunters]] have always mostly consisted of people who have been bitten. The rules of vampirism state that [[NoOntologicalInertia all potential vampires are freed from their curse if the "head vampire" who originated that strain is killed]] (an idea mocked in the ''VampireTheMasqueradeBloodlines'' video game).
* ''[[Film/{{Cursed 2005}} Cursed]]'' is the [[WolfMan werewolf]] version of this trope.
* ''Film/VanHelsing'', turned into [[WolfMan a werewolf]], must kill Dracula as a werewolf (as was prophesied), but Carl and Ana have to get the cure for lycanthropy to him before the stroke of midnight (as that's when he'll permanently be a werewolf). Fortunately for Van Helsing, the stroke of midnight lasts about twenty minutes.
* In ''GingerSnapsBackTheBeginning'', Ginger is given a prophecy that she will need to kill the infected child that bit her to avoid becoming a werewolf herself. In a subversion [[spoiler:the prophecy meant that she should kill the child "before" he bit her]].
* ''ReturnOfTheLivingDeadIII'' featured the heroine finding new and interesting ways to cause physical pain to keep from succumbing to her desire to eat folk.
* In ''TheBatmanVsDracula'', our hero finds a cure for vampirism, but it won't work on Dracula himself -- just those he's turned.
* Rayne from the first ''Film/ResidentEvil'' film gets bitten early on. She spends the rest of the time kicking ass to get everyone out and able to administer the cure to her. [[spoiler: Too bad they're too late]].
* Most of ''Film/{{District 9}}'' involves Wikus panicking about [[BalefulPolymorph turning into]] one of the HumanoidAliens that are [[FantasticRacism poorly treated refugees]] in [[UsefulNotes/TheApartheidEra Johannesburg]], before coming to his senses.
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[[folder: Literature]]
* Lucy Westenra and Mina Harker in ''{{Literature/Dracula}}''. For the former, it wasn't known what was weakening her till Van Helsing was called in. She would've probably been cured were it not for a few [[ContrivedCoincidence too]] [[DiabolusExMachina many]] bad circumstances. Mina is a bit more fortunate, since Dracula has to flee before he can fully transform her. She feels his presence within her spying on the hunters. And, when confronted by the brides near the end of the story, senses the vamprisim welling up in her.
* ''Literature/TheDresdenFiles'' features The Fellowship of Saint Giles, individuals who've been bitten by [[OurVampiresAreDifferent Red Court vampires]], gaining a portion of their power and their vampiric blood lust. However, since they haven't actually killed anyone by feeding, they haven't turned into the horrific bat-demons Red Court vampires ''really'' are. As part of their membership, they gain [[MarkedChange magical tattoos]] that help them keep the hunger in check and turn darker as they start to lose control.
* The ''Literature/GoodGhouls'' series -- the main character gets turned into a vampire and finds out the only way to get turned back is to kill her own maker. Several problems: firstly, it has to be ''her'' who kills her maker; secondly, any vampire higher up the chain, including her maker, is immune to any frontal attack from a lower-ranking vampire, so she has to be sneaky; and thirdly, she doesn't even know who turned her. In the end [[spoiler: she finds out who did it, but someone else kills him for something unrelated, so she's stuck as a vampire]].
* Darren of ''CirqueDuFreak''.
* Igor Dolinsky in ''Literature/NightWatcher''. Arguably, all the other "true vampires" qualify as well, as they are the ones who no longer need blood, though they aren't human anymore either (but then, neither is Igor, strictly speaking).
* Kostya in the ''Literature/{{Nightwatch}}'' series is [[spoiler: the only vampire to achieve "High Vampire" status without killing someone for blood]]. He became a biologist to prevent his vampirism from turning him into a monster. By the third book, he even [[spoiler: tries to turn every human being on the planet into Others]] just so he could be normal. [[spoiler: He fails]]
* In the ''TabletopGame/{{Ravenloft}}'' novel ''Literature/VampireOfTheMists'', Jander Sunstar was desperate to find a cure for his vampirism once he finally managed to become free to seek that cure; he was [[HeroicBSOD heartbroken]] to learn that there was no cure other than true death (and possibly not even then).\\
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Moreover, his specific background makes this [[BlackComedy grimly hilarious]]: until mists took him, as a Gold Elf back on [[TabletopGame/ForgottenRealms Faerun]] he was very close to the cure for undeath all those centuries. He didn't know it even exists mainly because the elves treat [[TooMuchForManToHandle High Magic]] as the greatest secret of Multiverse even when they ''know'' it's an OpenSecret to the present company, and he was just a young adventurer hanging out with humans.
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[[folder: Live Action TV]]
* One episode of ''Series/OdysseyFive'' had Taggart becoming a Synthetic, a [[{{Nanomachines}} nanomachine]]/[[ArtificialLimbs cyborg]]/[[ArtificialHuman android]]. He and his friends try to reverse it, but in the end he manages to hack the DeusEstMachina that made him into reverting the process.
* Dr. Kevin on ''Series/TheFortyFourHundred'' experimented on himself with [[SuperSerum Promicin]] to give himself powers. He got very mutated at first, but then found the cure for that.
* The eighties show ''Werewolf'' was built around this premise.
* Maya on ''Series/{{Heroes}}'' was desperate to get rid of her Superpower Of Involuntary Mass Destruction. Subverted in that she didn't have an ActionGirl bone in her body.
** She was beginning to bud into an ActionGirl when she voluntarily used her power against a FaceHeelTurn Mohinder, but that CharacterDevelopment came to an end.
* ''Series/{{Supernatural}}'':
** Gordon had the perfect set-up for becoming a Vampire Refugee, but since he knew there was no way to undo the change, he decided instead to kill Sam and then himself. [[spoiler: Instead, Sam killed him]].
** In season 6, this trope was played completely straight as [[spoiler: Dean]] gets bit, angsts, kicks some ass, and then gets cured at the end of the episode.
* On ''Series/MyBabysittersAVampire'', Sarah (the babysitter) was turned into a vampire by her boyfriend. However, she refuses to eat humans and exists on animal blood or blood substitutes while trying to find a cure.
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[[folder:Tabletop Games]]
* ''TabletopGame/MageTheAwakening'' features rare wizard refugees in the form of the Banishers. Banishers had their Awakening go wrong in some way or another (it's suggested more than a few of them [[MindRape literally gazed into the Abyss]]); as a result, the very use of magic causes them revulsion, and they spend much of their time hunting down and killing other mages out of the belief that magic is, at its core, evil.
* In ''TabletopGame/VampireTheMasquerade'', vampires would occasionally seek out Golconda, a mystical state of transcendence. Nobody could agree on ''what'' Golconda was, but one persistent rumor was that it would allow you to shake off the Embrace and become mortal again. One scenario had the villain trying to eat his way up his "family" tree to cure himself.
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[[folder:Video Games]]
* One of the paths in ''{{Tsukihime}}'' involves Shiki being increasingly possessed by an ancient vampire sorcerer, gaining the usual powers and bloodlust as his will rapidly erodes, and having to defend himself against his former companions. At first he holds out for a solution from the Church, but when that doesn't pan out he [[spoiler: [[WhenAllYouHaveIsAHammer resorts to his solution to everything else]]--turning his [[MagicalEye Mystic Eyes of Death Perception]] on and stabbing ''himself'' in an attempt to 'kill' the vampire's soul]].
** Also from the ''Tsukihime'' universe, Sion Eltnam Atlasia is entirely based on this. She even goes as far as to create an alchemical substitute for blood to deal with her cravings as a temporary measure. (It works, but only because of the extenuating circumstances.)
* This becomes an optional quest in ''Franchise/TheElderScrolls'': if the hero becomes a vampire. In ''[[VideoGame/TheElderScrollsIIDaggerfall Daggerfall]]'' it is offered by a vampire hunter who give you a choice instead of killing you (you can also drink the potion a witch conven ask you to transport). In ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'', it is given by reading a book about a cured vampire and doing a favor for Molag Bal, the "patron" daedra of vampires. In ''[[VideoGame/TheElderScrollsIVOblivion Oblivion]]'' it involves collecting a long list of ingredients to make a potion. In ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'' it involves trapping a human soul in a Black Soul Gem and giving it to a sorcerer, who sacrifices the soul to Oblivion as payment for your vampirism to be lifted.
* The plot of ''VideoGame/{{Bloodnet}}'' revolves around this.
* As does the plot of ''NeverwinterNights2: Mask of the Betrayer'', at least for a good-aligned character.
* ''VampireTheMasqueradeBloodlines'' features a "thin-blood" down by the beach who's desperately trying to find a way out of his new condition. You can either a) let him down easy and tell him that he can at least try to go on (un)living, or b) bilk him for all he's worth by selling him a "stake of pure rosewood" he can use to kill the "head vampire" or some vampirism-curing "unicorn blood." Or both.
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