[[quoteright:350:[[WesternAnimation/AdventureTime https://static.tvtropes.org/pmwiki/pub/images/nuke1.JPG]]]]
[[caption-width-right:350: [[FromBadToWorse As if a regular nuke wasn't scary enough!]]]]
Many works have the HolyHandGrenade: a purifying, holy blast of light and goodness which eradicates evil in sight, turning it into a dusty pile of ash.

[[InvertedTrope However, what happens if it gets reversed?]]

The Unholy Nuke tends to be a power fit for a BigBad: a devastating magic/technique/ritual fueled by unholy power, often the EvilCounterpart to a technique used by the good guys. Usually it involves BlackMagic and darkness, but other elements can play a role as well. Bonus points if it's PoweredByAForsakenChild. It may be a DangerousForbiddenTechnique. Sometimes an EvilKnockoff will use this as a dark mirror of one of the hero's own powers. In VideoGames, expect to see it used by the FinalBoss.

When handling the powers of darkness, don't forget that EvilIsNotAToy.

See also LightIsNotGood, CastingAShadow, PersonOfMassDestruction, and WorldWreckingWave. May or not be part of a YinYangBomb. Contrast HolyHandGrenade. See also FantasticNuke, where the emphasis is on the scale of the damage done regardless of whether the spell is specifically "unholy" or not.

----
!!Examples:

[[foldercontrol]]

[[folder:Anime & Manga]]
* ''Manga/{{Bleach}}'':
** Ulquiorra Cifer's Cero Oscuras is a jet black WaveMotionGun capable of disintegrating a significant portion of Las Noches's roof. His Lanza del Relampago is even worse. When he fails to hit his target with it, it sails off into the distance and creates an explosion that's roughly the same radius as las Noches and ''dwarfs'' it in height. To put both of those into perspective, Las Noches is the size of a city.
** [[SuperpoweredEvilSide Hollow Ichigo]]'s crimson Cero is even stronger than Ulquiorra's Cero Oscuras and overpowers it when the two clash, resulting in an enormous mushroom cloud.
** Coyote Starrk's spectral wolves are formed from his spiritual energy and explode with the force of a small nuke once they bite down on a target.
* ''Anime/DigimonFrontier'' has a few. Velgemon has Dark Obliteration and [=ShadowSeraphimon=] has Strike of the Seven Dark Stars (Seven Hells in the Japanese version). Lucemon provides a more unusual example with his Ultimate Sacrifice attack, which [[YinYangBomb uses light in addition to darkness]].
* In ''Anime/DragonBallGT'' there is the Revenge Death ball, powered by the hate of Baby's followers. Also [[FinalBoss Omega Shenron's]] negative energy ball, made from all the bad karma left over from all the sins on Earth.
* ''Manga/{{Naruto}}'' has the Bijudama, which literally means 'Tailed Beast Ball/Tailed Beast Bomb', the strongest attack of a Tailed Beast or its [[SealedInsideAPersonShapedCan Jinchuuriki]]. It gathers positive and negative chakra into a sphere, compresses it, and turns it into a WaveMotionGun that, at full power, can wipe off mountains and even ''islands''. The "unholy" part certainly fits when Naruto uses it in his [[SuperpoweredEvilSide berserk]] 4 / 6-tailed states, but Killer Bee is on good terms with his Beast and can use his full power at will. [[spoiler: When Naruto achieves the same rapport with Kurama, they pull off a Bijudama stronger than six others put together.]]
** The Ten-Tailed Beast has a far-more powerful version (which is a dark red instead of purple in the anime) that, at regular size, trumps even the strongest attacks the tailed beasts can pull off (and can travel nearly halfway around the world in just a couple of minutes to boot), and, at its largest, can wipe out ''an entire country''.
** Nagato destroyed Konoha via a giant gravity nuke which is a giant form of Shinra Tensei.
* ''Manga/FairyTail'':
** Jellal's magic Altairis consist in an extremely devastating orb. In the anime it sucks [[CastingAShadow all the shadows in the room towards it]] and makes Natsu sick just by standing near it. Later, Brain [[spoiler: / Zero]]'s spell "Genesis Zero" is pretty much this, only with a ''tsunami'' of black shadows shaped in the form of screaming spirits.
** The very first example in the series is the spell Abyss Break, created by combining the magics of earth, fire, water and air into an all-powerful dark blast of power. [[InformedAbility At least in theory, because the two times it was about to be used on-screen, it was never fired]].
** Hades's Grimiore Law, explicitly the EvilCounterpart to Makarov's [[HolyHandGrenade Fairy Law]]. Later, in the same saga, [[spoiler: [[OurDragonsAreDifferent Acknologia]]'s BreathWeapon]].
** [[spoiler:Black Mage Zeref]]'s Death Magic.
** Mard Geer's Memento Mori. Powerful enough to unleash CessationOfExistence and designed for the specific purpose of killing [[spoiler: Zeref]]
* ''Manga/{{Yaiba}}'' has the Devil King Sword's [[EarthShatteringKaboom Full Moon Blast]], used by Onimaru. Furthermore, all the attacks performed with the Devil King Sword are fueled by the negative feelings of the wielder.
* The ''Franchise/LyricalNanoha'' series has Diabolic Emission, a massive sphere of black energy that covers several city blocks and greatly harms targets caught within its blast radius. Its incantation is "In an ancient land, sink to the darkness."
** Notably, [[DarkIsNotEvil it's used by Hayate, one of the protagonists]].
* In ''Manga/OnePiece'' there's [[AGodAmI God]] [[ShockAndAwe Enel]] with his infamous, island-annihilating [[https://vignette.wikia.nocookie.net/onepiece/images/8/8b/Enel_using_Raigo_to_destroy_Angel_Island.png/revision/latest?cb Raigou]].
* ''Literature/Overlord2012'': Given [[VillainProtagonist who our]] [[OurLichesAreDifferent protagonist is]] and [[StoryBreakerPower what]] [[{{Necromancer}} he]] [[TheDarkArts can]] [[OneHitKO do]], the series naturally gives us a few examples.
** The Goal Of All Life Is Death is Ainz/Momonga's ultimate skill, which empowers [[OneHitKO instant death spells]] to ignore resistances [[CatastrophicCountdown but applies a delay of 12 seconds]]. The purpose of this spell in the game ''YGGDRASIL'' was to bypass heavy resistances to the normally AwesomeButImpractical death spells and allow them to hit normally [[NoSell invalid]] targets such as TheUndead or golems. [[TrappedInAnotherWorld In the New World]], it still does all this and more, when Ainz used it in combination with an area of effect death spell, it killed the entire target area so completely and utterly that the soil was turned to dead sand and the very air was rendered unbreathable.
** IƤ Shub-Niggurath is a Super-tier spell described as summoning a black cyclone of death magic that attempts to OneHitKO everything in its (massive) area of effect, then summons a number of high-level {{Eldritch Abomination}}s that serve the caster, depending on the number of creatures killed by the initial effect. And yes, it can be enhanced by the above for further devastation. When used in the aptly-named [[CurbStompBattle Massacre at Katze Plains]], the initial effect killed 70,000 soldiers and raised five level 90-ish Dark Young that slaughtered about 100,000 more, making this spell easily qualify as both an Unholy Nuke '''and''' a FantasticNuke.
** There is also [[NamesToRunAwayFromReallyFast Grand Catastrophe]], the signature spell of the [[GlassCannon World Disaster]] class (played by the guild's resident [[{{Chuunibyou}} edgelord]] Ulbert Alain Odle), which [[CoolButInefficient takes a good chunk out of the user's mana]] but surpasses the power of Super-Tier spells. We see Ulbert use it once in a side story, and it wipes out a room full of high-level elementals and takes a huge chunk of health out of the boss of the dungeon. That's for the "nuke" part. As for the "unholy" part, the name of the spell, the name of the class it's exclusive to, and its lore description as a manifestation of the wrath and sorrow of countless destroyed worlds should be a tip-off.
* ''Literature/{{Slayers}}'':
** Lina Inverse's Dragon Slave spell (when it is not PlayedForLaughs). Just listen to the incantation:
--->''One who is darker than twilight\\
One who is redder than flowing blood\\
Buried in the flow of time\\
In thy great name,\\
I hereby pledge myself to darkness\\
Those who stand before us in our way\\
All those who have become fools\\
Merge your power and mine\\
To grant destruction equally to all!!\\
'''DRAGON SLAVE!'''''
** The "one" to whom the incantation addresses is no one other than [[BigRedDevil Shabranigdo]], the {{Satan}} figure of the Slayers world. Yes, this spell is often PlayedForLaughs. It's that kind of series.
** There's also the Giga Slave spell, which calls upon the (technically ChaoticNeutral) Lord of Nightmares, creator of all things. It's powerful enough to make the Dragon Slave look like a capgun, since it literally erases whatever it touches from existence... but if the caster loses control, it will ''destroy the entire universe''. The risk comes from the fact that the spell doesn't just invoke the Lord of Nightmares' power [[spoiler:it briefly summons the Lord of Nightmares herself.]]
* ''Literature/ThatTimeIGotReincarnatedAsASlime'' has an entire class of magic that fits this. Literally called Nuclear magic, they are a type of magic that while not literally radioactive have devastating effects on their victims and if not restrained can raze entire nations.
** One of these spells is called Death Streak and is a forbidden technique that takes GeneticEngineeringIsTheNewNuke to an extreme. The spell has the effects of rewriting DNA randomly which kills the vast majority of its victims and turns any of the unlucky who survive into a monster[[note]]Although there have been no recorded survivors[[/note]] and has a radius of 10km. It has been a but a rumored ability ever since [[spoiler:it was used to wipe out the original AdvancedAncientHumans due to one of the original DemonLordsAndArchdevils being angered after they attempted a failed enslaving SummoningRitual.]]
[[/folder]]

[[folder:Comic Books]]

* In ''ComicBook/TheInvisibles'', the testing for the atomic bomb in Los Alamos was secretly a plot by Oppenheimer to bring an EldritchAbomination made of liquid information into our plane of reality.

[[/folder]]

[[folder:Fan Works]]
* An Italian ''Anime/DragonBallZ'' FanFiction features [[EnemyMine Super C17]] performing the "Lurkodama", described as the "Hell version" of the "Genkidama" and based on negative energy. Is used to form a YinYangBomb along with Gogeta's Genkidama.
* In the ''Fanfic/PonyPOVSeries''
** There's an unnamed dark magic spell that calls down ''Entropy's'' power into a gigantic WaveMotionGun. However, as [[DarkIsNotEvil Entropy herself is not evil]], nor is the spell itself, but it is ''dangerous'' and more or less drains all of the user's power, with potentially crippling side effects. ''Something'' bad also happens if its miscast but is not elaborated on. Sweetie Belle learned it from [[EvilMentor Chrysalis]], but is actually smart enough to use it as a GodzillaThreshold. The one time she's ever actually used it, it [[spoiler:was a OneHitKill on Nyarlathotrot's immensely powerful Dark Storm avatar and blew a massive hole straight through it.]]
** [[spoiler:Sweetie Belle and Nightmare Nihilis attempt to fire these at ''each other'' during the FinalBattle. The other characters have to stop them as ''two'' of them being fired at one another at the same time or either being miscast would be catastrophic.]]
[[/folder]]

[[folder:Films -- Live-Action]]
* In ''Film/{{Willow}}'' the main villain Bavmorda seeks to use the "Rite of Oblivion", an evil ritual that is intended to wipe its victim from existence itself, in order to destroy Elora Danan, the child who is prophesied to bring her down.
[[/folder]]

[[folder:Literature]]
* ''Literature/TheDresdenFiles'':
** The Darkhallow ritual from ''Literature/DeadBeat'' is the ultimate necromantic spell that kills everything, both living and spirit, within several miles' radius, then turns the caster into a PhysicalGod.
** There's also the bloodline curse from ''Literature/{{Changes}}'', which kills everyone related to a sacrificial victim. [[spoiler:It is ultimately used by Harry to destroy the entire Red Court.]]
* The Thought Bomb in ''Literature/DarthBane: Path of Destruction'' is one such example; using Sith energy, it obliterates all Force-sensitives (and for those close enough, all life-forms) within its radius,[[spoiler: including the Sith who used it.]]
* ''Literature/EmpireOfTheEast'': Inverted since the race of demons were created from nuclear explosions. The world's magic interpreted a nuclear explosion as something evil.
* The ''Psalms of Isaak'' series brings us the Seven Cacaphonic Deaths of Xhum Y'Zir, which is every bit as nasty as it sounds. Devised by the [[TheArchmage Wizard-King Xhum Y'Zir]] two thousand years ago using BloodMagic to avenge the deaths of his seven sons at the hands of rebels, it calls down [[ExactlyWhatItSaysOnTheTin seven successive cataclysms]] on the target location, which are collectively more than enough to kill anyone and level any structure within the vicinity, leaving behind only a charred wasteland filled with bones (since Y'Zir specifically designed the spell ''not'' to harm bone, presumably to leave evidence of his handiwork for anyone to see). This was responsible for devastating much of the known world in the backstory (Y'Zir went a ''little'' overboard in his revenge), and is considered the most powerful and [[BlackMagic darkest]] spell ever devised, to the point that the mere ''threat'' of it being rediscovered causes kings to FreakOut.
* ''Literature/TheChroniclesOfAmber'': Initiates of the Logrus possess the ability to summon elemental chaos, which effectively wipes anything they want out of existence, and if allowed to run wild can destroy a very large area before it runs out of energy. Merlin expressly compares it to a nuclear strike, and notes that it's so destructive there's almost no practical use for it.
* The backstory of ''Literature/TheMagiciansNephew'' establishes that Empress Jadis of Charn used a sinister FantasticNuke (complete with forbidden rituals involving a "Deplorable Word") to {{depopulat|ionBomb}}e her world so her sister wouldn't depose her. Turns out it's hard to get overthrown if you're the only being left alive.
* In ''Literature/TheFallenArises'', Vermillia uses a spell that not only creates an immense storm but increases its power before it drops a gigantic wall of lightning upon the Ravenstone estate.
* Creator/IsaacAsimov's "Literature/HellFire1956": Watching the expanding thermonuclear fireball in [[{{Overcrank}} extreme slow motion]], the audience realizes that the nuclear bomb is MadeOfEvil, and our viewpoint character decides FearIsTheAppropriateResponse.
[[/folder]]

[[folder:Tabletop Games]]
* In ''TabletopGame/{{Deadlands}}'': Hell on Earth, these are actual demonic MagiTek nukes. That [[AfterTheEnd destroy the world]].
* Another very literal example is from ''TabletopGame/GURPSTechnomancer'': the necronium bomb. Plain and simple nukes became unusable in that setting because they set off cataclysmic mana vortexes that may destroy the whole world in one blast, so the necromantic magical replacement was created.
* ''TabletopGame/DungeonsAndDragons'':
** The Talisman of Ultimate Evil. In the hands of an Evil HighPriest it could be used to open a flaming crack at the feet of a Good priest and send him or her to the center of the planet. 5[[superscript:th]] edition buffed it to be usable by any evil creature (though it gives an extra bonus to an evil Cleric or Paladin when held) and on '''any''' Good creature instead of just a Cleric or Paladin.
** Unholy Water causes damage to creatures from the Upper Outer planes (the planes of LawfulGood, NeutralGood and ChaoticGood).
** In the Second Edition of AD&D, the creature Death Knight is able to use a unique 20th level fireball, which was off-limits to player characters from this edition on (they were limited to 10th level fireballs).
* '' TabletopGame/Warhammer40000'' is full of these. Basically, any time Chaos is involved, expect Unholy Nukes to be flying thick and fast.
** Virus bombs are Imperial superweapons used to clear a planet of ''all'' life but leaving infrastructure intact. however, they've stopped using the ever since they found out using them strengthens Nurgle, the Chaos god of disease.
** On newly conquered worlds, the Word Bearers legion of Chaos Space Marines will build Gehemahnets: gigantic towers of blood, rubble and crushed bone that, when activated, transform the planet into a new Daemon World.
* ''TabletopGame/{{Exalted}}'' has a few of these to contrast the more enlightened ones:
** The Solar Circle Sorcery spell Total Annihilation isn't ''automatically'' unholy, given who wields it... but it's still the equivalent of a fantasy nuke, and relies on calling on a portion of the energy of Ligier, Hell's green sun.
** More directly descended from Ligier are Malfeas's more...''extreme'' Green Sun Nimbus Flare expansions, and Demon Emperor Shintai. Both of which contain actual radiation sickness on hell steroids.
** Mouth of the Void, a Void Circle Necromancy spell that does hideous amounts of damage to all creatures over a large area. Given its level, it can only be learned by Abyssals, who usually aren't on the side of goodness and light. [[DarkIsNotEvil Usually]].
* ''TabletopGame/MagicTheGathering'' has numerous black spells which qualify. [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=122423 Damnation]] is the most straightforward example, being the black EvilCounterpart to the white HolyHandGrenade [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=129808 Wrath of God]]. [[http://gatherer.wizards.com/Pages/Card/Details.aspx?name=plague+wind Plague Wind]] is similar, but destroys only your ''opponent''[='s=] creatures (and thus [[AwesomeButImpractical costs a lot more mana]]).
* The ''TabletopGame/OldWorldOfDarkness'' featured the [[TabletopGame/MageTheAscension Technocracy's]] "Code Ragnorok," a literal nuke, albeit a fairly small scale one, that detonates in the spirit world as well as the physical, destroying [[TabletopGame/WraithTheOblivion ghosts,]] spiritual beings and the souls of anyone unfortunate enough to be caught in the blast. To their credit they only used it once, against a potentially world-ending threat.
[[/folder]]

[[folder:Video Games]]
* The spell "Flare" from ''VideoGame/FinalFantasyI'' can be this, as its counterpart is the "Holy" spell from the White Mage. In ''VideoGame/FinalFantasyII'', Flare takes the form of a dark nuclear blast and some powerful evil enemies can cast it.
* From ''VideoGame/FinalFantasyVII'' there's the Meteor spell cast by Sephiroth. Note that in previous games Meteor was far more neutral (though less powerful).
* ''VideoGame/FinalFantasyIX'' has the spell "Doomsday", which damages everyone on the battlefield with the Shadow element, and is the most potent Black Magic spell. To use it effectively, you have to shield your party from that element.
* in ''Videogame/FinalFantasyXIV'', [[spoiler:Ultima]] becomes this, being the ultimate attack of the main storyline's final boss and explicitly mentioned as being powered by the resident GodOfEvil, [[spoiler:Zodiark]].
* The "Unholy Darkness"[[note]]aka "Dark Holy"[[/note]] spell from ''VideoGame/FinalFantasyTactics'', used exclusively by the highest order of demons, fits this bill to a T. Its animation even parallels the Holy spell (FadeToBlack vs FadeToWhite, ending with a deathly scream instead of an angelic choir).
* In ''VideoGame/MassEffect2'', when [[VillainOverride possessing a puppet]], the Reaper Harbinger has a special version of of the "Warp" ability that probably qualifies (it's yellow with ominous black lightning as opposed to the usual blue).
* In ''[[VideoGame/DarkForcesSaga Jedi Knight]]'' Jerec can use the "Destruction" Force Power. It's a Dark Side attack that consist in a fiery ball of flames and negative energy that destroy everything on its path.
* In ''VideoGame/HeroesOfMightAndMagic'', Death Ripple damages all non-undead units on the battlefield. Unholy Word from ''V'' does the same, but also excludes demons.
** Armageddon from the third game probably qualifies too. It's a tier 4 spell that rains fire from the skies, dealing heavy damage to all units on the battlefield. [[AwesomeButImpractical Including the caster's]], making the spell difficult to use unless one's army consists heavily of units immune to fire or immune to magic at least up to tier 4.
** On a related note, the Armageddon's Blade, capable according to the lore of "setting the world on fire" and created by a Kreegan (this game's equivalent of [[OurDemonsAreDifferent demons]], although they're actually more like [[AliensAreBastards evil aliens]]) qualifies especially. In gameplay, the Blade provides a not insignificant boost to a hero's stats and gives the user the ability to cast, at Expert level, an Armageddon spell that deals no damage to allies. Finding the sword in a non-campaign map gives the following ominous message:
-->''"Deep beneath the earth, you find a vault of the Ancients from before the Silence. Inside you find a sealed casket, deeply etched with dire warnings. Ignoring them, you break the seal. Inside, you find Armageddon's Blade."''
* ''VideoGame/MightAndMagic'' has, like the ''[=HoMaM=]'' series, the Armageddon spell that is housed by Dark Magic school and deals damage to everything on map including your party. It can be cast only limited number of times per day and does not work in dungeons. The version from ''VII'' and ''VIII'' probably fits the bill better, as it explicitly deals dark magic damage (unlike in ''VI'' where it was just magic damage) but this difference aside, it's the same spell.
* ''VideoGame/{{Spellforce}}'': The BlackMagic sub-branch of Death has the quickest damage output in the game.
* ''VideoGame/SecretOfMana'' had the unholy nukes dark force and evil gate.
* In ''VideoGame/ShinMegamiTenseiNINE'', the Desire Disks have this effect when destroyed. In addition to causing an explosion powerful enough to level a building, the resulting cloud of [[HumanResources Desire Energy]] attracts demons to the area.
* In ''VideoGame/{{Suikoden}}'', pretty much all of the Soul Eater's spells are considered this.
* The Ultimate Insult from ''VideoGame/EscapeFromMonkeyIsland'' is one of the most powerful Voodoo artifacts around. Though it's not lethal for the body, but instead annihilates the spirit, leaving its victims weak-willed and cowardly.
* The ''Demonic Megiddo'' from the ''Franchise/{{Castlevania}}'' series is the Dark Lord's most powerful attack, and tends to be a OneHitKill super powerful spell used mainly by Dracula or Death.
** In ''VideoGame/CastlevaniaCurseOfDarkness'', one type of magician Innocent Devil can cast a similar spell dubbed Demonic Disaster.
* The Carronnade from ''VideoGame/BreathOfFireIV'' is possibly the most horrific example of this trope ever, fueling its Unholy Nukes with soul-crushing torment and turning that anguish into a weapon of mass destruction that turns the area for ''miles'' around into a nightmare that gives Hell a run for its money.
* ''VideoGame/MagicalGirlLyricalNanohaAsPortable: The Gears of Destiny'' gives the Ruler of Darkness, Lord Dearche, a new Limit Break called Juggernaut, which is her equivalent to Hayate's [[WaveMotionGun Ragnarok]]. In contrast to Hayate's converging beam of white light, she rains down several black beams around her target then detonates them, engulfing her opponent and the battlefield in several explosions of darkness.
* While the series typically features demons armed with BlackMagic curses versus angels equipped with [[HolyHandGrenade Holy Hand Grenades]], the first ''VideoGame/NexusWar'' game made an exception for Breath of the Dead Child, a nuke powered by [[ExactlyWhatItSaysOnTheTin the breaths of dying children]] harvested from [[NightmareFuel haunted pediatric wards]]. The sequel's version is powered by [[FromBadToWorse dying breaths everywhere]] and is no longer age-specific.
* ''VideoGame/WarcraftIII'':
** The Death Coil spell is the Holy Light spell in reverse, healing a huge amount of life of an allied Undead unit or harming a living enemy for half the amount. In ''VideoGame/WarcraftII'', it was (comparatively) even deadlier, as it could one-shot most units, two-shot the rest, and healed the SquishyWizard caster with every cast.
** The Undead faction is the only one where ''every'' HeroUnit has an immediate high-damage spell targeting at least one unit (Impale and Carrion Swarm do damage in a line, Impale also adds stun, and Frost Nova damages all units around the target and slows them), meaning three Undead heroes can reduce an enemy hero's life to nothing in less than five seconds, forcing a retreat.
* ''VideoGame/Dota2'' has [[CastingAShadow Nevermore, the Shadow Fiend]], whose "Requiem of Souls" spell unleashes the [[SoulEating souls he stole]] for massive damage in a circular area.
* ''VideoGame/CopyKitty'': The "Vestige of the Lost", the most powerful BlackMagic spell in existence. Legend states that the spell works by opening a portal to Hell itself and allowing evil gods to briefly wreak havoc on the world. The spell is so deadly that its only known wielder (the game's {{Superboss}}) cannot channel the full power of the spell, and has to split it into three lesser spells. Boki, not knowing the dangers, copies all three components and uses the full spell against the {{Superboss}}. The result kills the previously invincible boss in one blow, crashes the training simulation, and knocks Boki out cold, terrifying her teacher, who hadn't believed she would be capable of copying that power.
** Turns out that, if you're really lucky in Pandemonium Mode, you can get all three spells and use "Vestige of the Lost" during normal gameplay. It has infinite range and lasts long enough to pulverize multiple waves of enemies, but [[HPToOne Boki's health will fall to 1 in the process]].
* ''VisualNovel/FaultMilestoneTwo'': Melano -- the BigBad -- flicks a tiny glowing orange spell at the protagonists when they dismiss her claim of omnipotence... which creates a massive explosion that kills the party and devastates the surrounding area with a magical version of radiation poisoning. She then [[RippleEffectProofMemory rewinds time while letting the party keep the memories of their deaths and what happened afterwards]].
* ''VideoGame/KingdomOfLoathing'': One of the damage types in the game is Sleaze, which is defined as "Moral corruption, often having to do with laziness", technically making it a form of weaponized evil...PlayedForLaughs.
* ''VideoGame/EldenRing'': The Scarlet Aeonia flower that blooms when the demigod Malenia gives in to the Scarlet Rot ravaging her body [[spoiler:(and later learnable as an offensive spell by the player)]] is treated like this. In the backstory of the game, the flower bloomed during her fight with one of her demigod siblings and the resulting spread of Scarlet Rot turned a massive chunk of The Lands Between into an uninhabitable hellscape of poisonous swamps and mutated monsters.
[[/folder]]

[[folder:Web Comics]]
* In ''Webcomic/EightBitTheater'' Black Mage mentions that he gained his [[KamehameHadoken Hadoken spell]] (essentially an all-purpose nuke) through sacrificing children to his wanton gods of evil. [[ComedicSociopath This surprises no one]]. It's also mentioned that it's powered by consuming love from the universe, and that the divorce rate rises slightly every time he uses it.
* Webcomic/DominicDeegan has a rare example of one used by a good character. Dark Soul Burst is a spell powered by anger and hatred, and is typically used by Luna when someone REALLY pisses her off. The first time it's used, it knocks out Siegfried, a rather strong royal knight, in a single shot.
* In ''Webcomic/TheOrderOfTheStick'', the "Familicide" spell is an extremely powerful necromantic spell that kills ''everyone related to its target, '''and everyone related to them'''''. There are dire consequences when [[spoiler:Spliced V uses it against a Black Dragon to avert a CycleOfRevenge]], since [[spoiler:Girard [[MeaningfulName Draketooth]] and his entire clan, the guardians of one of the Gates, [[DraconicHumanoid were related to that dragon]].]]
* In ''Webcomic/{{Heartcore}}'', this is combined with SuicideAttack and BloodMagic for Volaster's most powerful spell, Blast Bomb: by allowing himself to be injured to the point of bleeding his volatile salamander demon blood profusely, Volaster can set himself off as a living nuclear bomb. He uses this spell in the Beastman capital to destroy it and drive the Beastman race to the brink of extinction.
[[/folder]]

[[folder:Web Original]]
* ''Literature/VivereMilitareEst'' has about as close to a literal example as you can get in the form of despoiler bombs. Equipped with a computer able to recite spells faster than any human (and with less [[GoMadFromTheRevelation corruption]] because computers don't have souls of their own) and "fuel" in the form of [[{{Mana}} gastplasm]] extracted from human and animal sacrifices, the despoiler bomb consumes the souls of everybody caught in the blast radius and turns any place targeted with one into an EldritchLocation, and winds up replacing nuclear weapons in the {{Weird|HistoricalWar}} [[SpaceColdWar Cold War]] of its AlternateHistory setting. Kyoto, which was targeted with one in the closing days of UsefulNotes/WorldWarII, is ''still'' uninhabitable in the 21st century, and it's estimated that, if WorldWarIII were fought with despoiler bombs, it would tear a hole in reality big enough to destroy the Earth. Nuclear weapons do still exist, but they're only used by the [[AntiMagicalFaction doggedly anti-preternatural]] [[BadassIsraeli Israelis]].
[[/folder]]

[[folder:Western Animation]]
* The full extent of its effects is unknown, but the bomb that ended the [[ApocalypseHow Great Mushroom War]] in ''WesternAnimation/AdventureTime'' almost certainly qualifies. It does not appear to cause an explosion of the magnitude of a conventional nuke, but [[spoiler: it exudes a greenish cloud of what appear to be tormented souls and creates a largish puddle of green toxic waste that mutates the first person exposed to it into an OmnicidalManiac [[OurLichesAreDifferent Lich]] powerful enough to serve as the series' BigBad]].
* ''WesternAnimation/StarVsTheForcesOfEvil'': Eclipsa has two spells that qualify as this: the first is "the darkest spell" that she taught to [[spoiler:Moon to kill Toffee]], being the only spell in existence to be able to permanently harm an immortal, and the second is Black Velvet Inferno, the spell she used against [[spoiler:her own daughter, Meteora,]] to stop the latter's destructive rampage against Star and Mewni. The spell encloses the victim in an orb of dark magic, then a massive energy release inside the orb fries the victim to a crisp. Eclipsa's mother Solaria was apparently trying to come up with a Total Annihilation Spell in order to [[VanHelsingHateCrime exterminate monsterkind]] once and for all. Fortunately she failed, but she expected Eclipsa to [[TakeUpMySword succeed her]] and finish the spell in her place. At some point Eclipsa did succeed and this spell, which before even being cast exists within the wand, risks acting ''on its own'' and eliminating ''every dimension'', including the barriers between them. When she does cast it, it emits a massive butterfly-winged skull made of energy that effortlessly melts through everything in its path, and keeps going into the horizon after striking its target.
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