Transsexual people are those who identify with a gender that is not typically associated with their assigned sex. Some transsexual people pursue medical means (e.g. hormone replacement, surgery, etc.) to help mitigate gender dysphoria, but others don't or can't change the shape of their bodies very much. Transsexual people are not a new group, with a presence documented as far back as the [[OlderThanFeudalism Roman Empire]]. They can be a source of interesting {{Conflict}} in a story, with coming out stories that have the possibility for more visual representation of change. See the Useful Notes on UsefulNotes/{{Transgender}} people for a more RealLife oriented description of transsexual people.

Now for some definitions:
* [[QueerAsTropes Homosexuality]] is a completely separate issue. Transsexuality is not [[TransEqualsGay gayness turned]] UpToEleven, as convenient as that would be. A strictly gay man would generally not be attracted to an [=MtF=] transsexual, for example. The "T" is in "LGBT" because transphobia and homophobia have similar motives - both defy the main idea of what a man or a woman "is" or "should be" - but they are distinct groups. It's also a myth that all trans people are heterosexual (attracted to the gender opposite to their identity). Trans people run the full gamut of sexual orientation, just like anyone else.
* "Transgender" is generally used as an umbrella term for people whose identified gender does not match the gender they were assigned at birth. Within the trans community there is actually debate about [[http://en.wikipedia.org/wiki/Transgender#Transgender_vs._transsexual "transsexual" v. "transgender"]] (with the core of the debate centered around physically "transitioning" from one sex to another, via surgery and hormone therapy). As can be seen just in the identifications on this page, transsexuals, transgenders, and transvestites are frequently conflated.
* "Androgyne[[note]]A gender identity found "in between" male and female.[[/note]]", "Agender[[note]]A gender identity that is lacking an innate sense of their gender. Note that this does not necessarily mean that this person does not experience gender dysphoria.[[/note]]", "Gender Variant[[note]]A catch-all term for variations in gender apart from male or female[[/note]]", and "Genderqueer[[note]]Similar to gender variant, but you're relatively more likely to run into someone who self-identifies as genderqueer, and this isn't an umbrella term.[[/note]]" are various terms used for different types of people who reject the gender binary entirely.
* Genderfluid, Bi-gender, or Tri-gender refers to people whose gender changes over time, whether between many identities or just two or three. This can be as often as daily or as rarely as once in a decade, and can have triggers or happen on its own. If these people's identities end up matching up to their birth-assigned gender at some points, they may consider themselves "part cis". Not to be confused with multiple personality disorder.
* AFAB[[note]]Assigned Female At Birth[[/note]]/FAAB[[note]]Female Assigned At Birth[[/note]]/CAFAB[[note]]Coercively Assigned Female At Birth[[/note]], AMAB[[note]]Assigned Male At Birth[[/note]]/MAAB[[note]]Male Assigned At Birth[[/note]]/CAMAB[[note]]:Coercively Assigned Male At Birth[[/note]] and UAB[[note]]Unassigned At Birth[[/note]] refers to the "birth gender" of a person. Some trans people prefer this, as terms like [=FtM/MtF=] exclude non-binaries or {{intersex}} people. Also, because calling a someone's body "a girl body", for instance, because it has ovaries and whatnot can be offensive - it doesn't belong to a girl, therefore, it is not a girl's body and its actual contents are irrelevant to that fact. (The same obviously goes for "male" bodies).
* [[{{Crossdresser}} "Crossdresser" and "Transvestite"]] refer to wearing the clothing of the opposite sex. They may or may not be used interchangeably and ''do not'' necessarily entail either cross-gender identification or homosexuality, although they also do not preclude either. [[http://en.wikipedia.org/wiki/Transvestic_fetishism That other wiki]] has an entry for "transvestic fetishism".
* {{Drag Queen}}s and Kings are performers who dress as caricatures of the opposite gender, but most of them identify as their biological sex in their day-to-day lives. ''They'' tend to be CampGay men and {{Butch Lesbian}}s gender-bending to entertain, hence [[TransEqualsGay the mistaken notion that a transsexual is "super" gay]]. Very few drag performers are trans; those that are will make themselves look ''less'' convincing (thick makeup, huge hair, GagBoobs, etc.) in their drag personas.
* "Intersex" (inaccurately "{{Hermaphrodite}}") refers to atypical ''physical'' development and is more common than you think; it is not related to the above but may occasionally lead to them if the doctors decided for the newborn before surgically assigning sex organs. There's a small but growing tendency to go with the phenotype and identify as intersexed.
* [[http://cdandor.tumblr.com/post/3569062893/words-that-are-transphobic-and-why-poster-for-the "Shemale," "He-She," "Tranny,"]] [[ItIsDehumanizing "It," etc.]] are considered deadly insults. If you don't know if you have NWordPrivileges, you don't.
* ''Cissexual'', ''Cisgender'' or just ''Cis'' is the opposite of transsexual, the majority: someone whose gender identity matches up with their birth sex [[note]]"Cis" is a Latin prefix that is the opposite of "trans," meaning "not across," as in chemistry or "cisatlantic/transatlantic."[[/note]] "Non-trans" is also used, but just saying "normal" or "real" or just "man"/"woman" as opposed to "trans man"/"trans woman" is basically saying that trans people aren't ''really'' their gender.
* The term "trans" is often used as an umbrella term for all non-cissexuals; the asterisk represents the various endings (transgender, transsexual, transvestite, etc.) though it includes people with identities that don't start with the "trans-" prefix, like the aforementioned genderqueer or agender.

Any and all of the above may be characterized as transsexuality. Confused yet?

Most transsexuals in TV and the Media are male-to-female ([=MtF=], trans women). Female-to-male ([=FtM=], trans men) transsexuals are much less common in mainstream fiction, but statistically are about as common in RealLife (Current estimates are somewhere in the vicinity of 1 in 200 for social transition.)

[[OnceAcceptableTargets Many recent portrayals]] of transpeople tend to be fairly sympathetic. However, bigoted and inaccurate "trans panic" jokes that portray transpeople (usually women) as deceptive cross-dressers ("Oh no, the hot chick is really a man!") are still common -- and as this line of reasoning is [[http://en.wikipedia.org/wiki/Trans_panic often a motive]] [[http://en.wikipedia.org/wiki/Murder_of_Gwen_Araujo for murder]] in real life, this type of humor goes beyond mere UnfortunateImplications.

Contrast GenderBender, which is about men and women changing their physical sex through magic or AppliedPhlebotinum (though occasionally such stories ''also'' involve transsexual characters.) Also contrast EasySexChange, which is this trope plus TheyJustDidntCare. Unlike GenderBender, the Easy Sex Change has at least a pretense of realism, but minimizes or ignores many physical, psychological, and/or social complications of the sex change.

For another common example of TheyJustDidntCare as applied to this trope, see TransEqualsGay.

Has nothing to do with {{Transhuman}}s; the shared root Trans [[note]]Latin for "across", "beyond" or "on the opposite side"[[/note]] is the only commonality, and even then both terms use different definitions of it. The root Trans here means "opposite" roughly.
----
!!Examples:

[[foldercontrol]]

[[folder:Advertisement]]
* [[http://www.youtube.com/watch?v=4VrGVVAVIbQ In a Sprite ad for Latin-America]], a guy reunites with his school friends, and each encounter finishes with "[insert friend's childhood nickname], eeeeeeeh!" and a hug/group hug. The last one, nicknamed "Oso" ("bear" in Spanish), turns out to have transitioned from male to female; we only see her from the back but she's clearly using heels and a minidress. What do her friends do? "Oso...? [blinkblink] [[CrowningMomentOfHeartwarming OSO!! EEEEEEEH! [group hug]".]]
[[/folder]]

[[folder:Anime and Manga]]
* In the manga adaption of ''Anime/WelcomeToTheNHK'', Yamazaki befriends a pre-op transsexual, and even gets a job to pay for her operation. Unfortunately, this charity offends her, and she ends the friendship
* Maho, one of the two main characters in the manga ''DoubleHouse'', is a transwoman, as are a number of the secondary characters.
* Shouko Aihara from ''Gakuen Saimin Reido'' used to be a male bully known as Akira Aihara until he is hypnotized by Satou Futoshi(The fat guy he usually bullied) into taking hormone pills until that body reaches the female shape and Satou later brainwashed her and altering her personality.
* Isabella in ''ParadiseKiss'' seems to be a non-operative transgender woman.
* The ''[[{{Trigun}} Trigun Maximum]]'' manga has Elendira the Crimsonnail, although she is presented as a transvestite. Vash is the only one who briefly recognizes her as female, and then only to insult her. She glared and said 'a woman like you' out of Wolfwood when he called her a guy one time. Apart from Meryl categorizing her as a transvestite (and complimenting her figure) after she falls out of the sky, it doesn't really come up otherwise; people are busy. The actual question is how everyone can tell by looking at her.
* Arakune / Arachnee in ''AngelSanctuary''. In her case, she doesn't have reassignment surgery because it'd mean she would lose some of her strength.
** Also, [[spoiler: Laila/Sevoth-Tart/Sevy/Sebi]] is a [[spoiler:sort-of?]] transman. In this character's case, [[spoiler: it isn't because she identifies as male but as a result of the trauma of being gang-raped. Because of this, 'she' lives in denial of her previous existence as Laila, and even goes as far as undergoing treatment to inhibit her breasts. She also wears a machine that makes her voice sound 'masculine'.]]. Towards the end of the manga, [[spoiler: 'she' is discovered and goes back to being female; she even becomes pregnant after Sandalphon rapes her]].
** ''AngelSanctuary'' also has [[spoiler: Belial, the Mad Hatter]], who explicitly identifies as neither male nor female and deliberately resorts to genderfuck clothing and make-up to play on his/her androgynous appearance. Some scenes shows her/him as more masculine or feminine than other ones, though; in the presence of [[spoiler: Kira or of Lucifer, Belial]] usually looks very much like a wounded FemmeFatale. In the purely biological sense, [[spoiler: s/he is a breastless female]]. To make this powerful [[TricksterArchetype Trickster]] character even more complex in terms of gender and sexuality, Kaori Yuki also makes him/her omnisexual. For example, s/he is madly in love with [[spoiler: Lucifer]] and as proof of his/her devotion, [[spoiler: sacrifices to him 1,000 virgin women that s/he loved.]] S/he even seduces [[spoiler: Kurai]] partly by taking the appearance of one of her male suitors and generally acting like a campy male, with the result that she is dumbfounded when she discovers that Belial is [[UnsettlingGenderReveal biologically female]]. This character is truly as genderqueer as you can possibly get.
*** Kurai herself has some trouble in identifying as female, although it's probably partly because she starts off as a young teenager. She seems to have less trouble with her gender identity once [[spoiler: she 'develops' at an extremely quick rate]]. However, she explicitly compares herself to Arachne, mentioning that their families had problems with Arachne being what they thought was a [[{{Crossdresser}} 'transvestite']] and Kurai being a '{{tomboy}}'.
** [[spoiler: Alexiel and Rosiel, anyone?]]. While she laments to have been [[spoiler: born female, because she had too many feelings to deal with and wished to be reborn as male (which led to her reincarnation as Setsuna)]]. Although she seems to embrace her true self in the end, she still has gender issues. Meanwhile, her brother [[spoiler: ''wants'' to be her, he has her beauty/face and even pretends to be female once.]]
* ''FamilyCompo'' has so many Transsexuals and {{Crossdresser}}s that it's hard to count. The main character's adoptive parents ('''both''' of them -- that is, the dad is biologically female, the mom is biologically male. Both are non-operative transsexuals.), his adoptive father's assistants (all transsexuals, some post-op, some not), several dozen bit characters, and one of the [[WillTheyOrWontThey character's love interests]] -- his adoptive sister -- may or may not be a biological male, given that about every 6 months she'd switch genders as she was growing up ([[spoiler: It's never explained in the manga, and in the end, the character realizes it doesn't really matter anyway.]]) Oh, and given how 'effeminate' the main character is, he ends up in drag just about every other storyline.
* [[spoiler: Seiko]] from ''LovelyComplex''.
* Akari in ''SamuraiDeeperKyo'' was raised as a woman to make her shamanic powers stronger, and it stuck.
** The series mostly ignores the implications of transgenderism (except as gag fodder) and makes her the strongest of Kyo's followers and, therefore, a complete {{Badass}}.
* Commander Teral from ''GodSigma'' is literally a woman in a fairly masculine man's body. Ironically, she's the noble prince-type of the story despite being one of the main villains. She gets very little snark, which is pretty open-minded for an early 80s show.
* Shuuichi Nitori ([=MtF=]) and Yoshino Takatsuki ([=FtM=]) from ''WanderingSon''. Also their adult friend Yuki Yoshida ([=MtF=]), who is implied to have had a full physical transition, as well as Nitori's classmate Makoto Ariga ([=MtF=]) and Taiichirou Ebina ([=MtF=]). [[spoiler: Though Nitori, Yuki and presumably Makoto and Ebina remain as this trope... Takatsuki might have subverted it.]]
* Hibari Oozora of ''Manga/StopHibarikun'', who has loudly voiced her disappointment in the fact that she doesn't have breasts and plans to eventually marry Kousaku. The anime also avoids ever showing her naked chest despite the fact that she doesn't have anything to hide there.
** There's also [[spoiler: a random island girl that looks almost exactly like Hibari (resulting in another UnsettlingGenderReveal moment for Kousaku]] and [[spoiler: a girlfriend of Ibari's -- one whom he doesn't know is trans]].
* The protagonist of RiyokoIkeda's ''Manga/{{Claudine}}'', Claudine de Montesse. He's a very {{woobie}}-like female-to-male transman with a sensitive heart and horrible luck, who ever since he was a child was sure that he was a male, and [[spoiler: in the end [[BuryYourGays commits suicide]] after his lover Sirene gets engaged to his eldest brother Andre. His doctor (who doubles as NarratorAllAlong) reminiscences about Claudine's case, and concludes that he was right into identifying as a male.]]
* Futaba Aoi from ''Manga/YoureUnderArrest'', one of the prettier woman officers. In an episode in the second season where she asks for help with a date with a man, Aoi says, "I have the body of a man, but the heart of a woman".
** It may have been confirmed, [[GettingCrapPastTheRadar though without saying any transgender related terms.]] "Aoi-chan" is thought of as being female almost all of the time, and transsexuality tropes have appeared relating to her. Episode 6 all but goes out and says "transsexual"; A character says that her "natural flow" leads toward her being a woman, and goes on to say that he doesn't care if she's male or female (signifying she's a girl instead of a crossdresser). The original manga implies she had interests in crossdressing and feminine thoughts ''before'' becoming a police officer too.
* Hana in ''TokyoGodfathers'' says, "I am a mistake made by God. In my heart, I am a woman."
* The BL light novel and anime ''LightNovel/{{Sukisho}}'' has transgender TeamMom Nanami .
* ''TheDayOfRevolution'' is a two volume manga series about an intersex but genetically female high school boy who elects (under pressure from his family) to become a girl because he sees it as a choice between being an 'incomplete man' or a 'complete woman'. he quickly finds that letting go of his old male identity isn't going to be easy or simple.
* The {{Yuri}} anthology ''Mermaid Line'' has a SliceOfLife story where a male to female transsexual and her [[IfItsYouItsOkay (apparently bisexual)]] fiancé decide what to do about her transition.
* [[SpellMyNameWithAnS Criff/Cliff]] from InfiniteRyvius is a male to female transsexual who transitioned a good time before the series started. You'd never know if it weren't for WordOfGod statements and a blink-and-you-will-miss-it line from her sister.
* One of the stories in ''PetShopOfHorrors'' has Leon investigating the murder of who turned out to be a transgender man with a beautiful female alternate persona, who kept rooms of aquariums of transgender fish and a virtual pet of a beautiful female fish. She was killed by the bartender who had a crush on her when he found out.
** And in the Tokyo version Count D and a friend visit a club for transvestites and transsexual women, all of whom are portrayed very sympathetically. The bartender/owner comments that they're just women looking for husbands and also makes reference to a place a floor up where men can meet other likeminded men. Count D is apparently on good terms with some of them and has tea with the group on a regular basis.
* ''Strange Mansion'' features a StalkerWithACrush who moves into the title apartment to be near her bishounen classmate. She discovers that her crush became a woman to be with his/her love interest (he was a bit disappointed that his first declaration of love came from a man but handled it calmly), which causes a HeroicBSOD. Of course, the [=MtF=] character's wealthy conservative parents know nothing.
* The main character from AiNoShintairiku, Nikotama Sara, is a male-to-female transsexual.
* A little known manga titled ''Gender Identity Disorder'' follows the life of an [=FtM=] transsexual. It begins with his childhood (telling his father he wants Santa to give him a penis for Christmas), and ends with him transitioned and leading a successful life, reconciling with his father before he dies.
* Arisugawa "Alice" Kintarou from ''LightNovel/MariaSamaGaMiteru''.
* Subverted (yes, subverted) with Nuriko from FushigiYuugi, who is presented for quite some time as being a perfectly normal woman until the bizarre and unnecessary reveal or retcon that Nuriko ''actually'' dresses like a woman due to dead relative issues. Because it's okay to be a mess of Norman Bates-y psychological issues, but a trannie? That would just be ''weird''. [[InternetBackdraft Be careful where and when you bring this up, though.]]
** Weirdly enough, there is a very freudian theory about transsexuality which actually goes like this - the theory is that people are trans because they lost - or became too close to - their opposite sex parent/other family member, and they end up wanting to be the opposite gender due to wanting to "keep them alive". Again, this is the sort of theory which a lot of people disagree with/think is bullshit, [[InternetBackdraft so it's best not to discuss this either.]]
* Yoshiki Kitazawa from the manga ''{{Gravitation}}'' is an [=MtF=] transsexual. In the first series, she's only had hormones to encourage breast growth but her lower half is still physically male. In the sequel, EX, she finishes her surgery on her lower half as well, like she's wanted to since she was 14-15 as stated in the fanbook.
* Izumi Nachi/Lady Nachi in ''MugenDensetsuTakamagahara: Dream Saga'' is pre-operative in Nakatsukuni, and post-operative in Takamagahara. She takes full advantage of her female form, attempting to become the perfect girlfriend that she could never be in Nakatsukuni because of societal expectations... to a guy that didn't want her. The rest of Nachi's evolution goes from ClingyJealousGirl to IWantMyBelovedToBeHappy.
* One episode of ''LightNovel/DirtyPair'' featured a wealthy business owner framing his son's fiance for kidnapping when really they were trying to elope. It's eventually revealed that the reason he objects to their marriage is because the fiance used to be a man and had a sex change (there was nothing to suggest this other than the woman was tall). After a moment of surprise, Kei and Yuri respond: "So what? That's so closed-minded!" and "In these days, one out of every ten people has had a sex change!"
* Grell from ''BlackButler'' is male-to-female transsexual, as Toboso Yana eventually made clear. As the series is set in VictorianBritain, she's necessarily non-operative, which has led many to think she's a flamboyantly gay man.
* Celebrity stylist Nao from ''IceRevolution'', who forgives uber-{{Tomboy}} Masaki for destroying her favorite scissors, gives a makeover that makes her appear truly feminine "on camera" for the first time, and even leaves the fee for later. Notably, she is the ''only person'' outside of Masaki's friends and family who can tell she's a girl at first sight.
-->'''Masaki:''' How did you... know I'm a... girl...?\\
'''Nao:''' Isn't it obvious?\\
'''Masaki:''' (''is completely mystified'')
** After TheReveal that Nao is a male to female transsexual, Nao tells Masaki that they're NotSoDifferent: both of them had a hyper-aggressive male appearance that they're no longer comfortable with.
* [[spoiler: Mikihisa]] from LevelE is female-to-male and has felt male since he was four. [[spoiler: After much tribulation, the alien princess who's in love with him gives him a really high-tech sex reassignment. With some other modifications to weed out the DepopulationBomb virus in the princess' body, they live happily ever after]].
** [[spoiler: Mikihisa is actually intersexed. The manga outright states that he has male chromossomes, but a female body. And the aforementioned alien princess carries a virus that can render the entire male population of Earth sterile (and she doesn't really care if that happens). Said virus becomes able to propagate itself by air after she has sex with her chosen mate (Mikihisa). The prince of Dogura however, creates a clone of Mikihisa and infuses it with a pathogen that will neutralize the virus, and relocates the real Mikihisa to another location and alters his memories so he won't remember what happened. In the end Mikihisa got the body he always wanted, and humanity is saved since the alien princess doesn't notice that she is dating a clone, and her species mate only once in a lifetime.]]
* Mitsuko, the main characters' sidekick in ''Leviathan'', is a transwoman, and while her characterization in itself is fine, her friends take every opportunity to point out that she's not a ''real'' woman and use mildly offensive terms to refer to her. And this is all supposed to be played for laughs.
* A chapter of the manga ''Manga/HowIBecameAPokemonCard'' is about a [=FtM=] named Akari, who has to wear a female school uniform since he's entering middle school. He gets a Pikachu for his birthday, which he's mad about since it's not a "cool" Pokémon but a "[[RidiculouslyCuteCritter cute]]" one. He eventually got over it and learned that it doesn't matter what a Pokémon looks like, that they all can be [[BadassAdorable cool]].
* ''Manga/GenkakuPicasso'' has [[spoiler:[[LongHairedPrettyBoy Yosuke]] [[NiceGuy Hishida]]]], who is explicitly described as suffering from [[http://en.wikipedia.org/wiki/Gender_identity_disorder Gender identity disorder]]. She puts on a good show of acting like a normal boy, so this causes some problems when [[spoiler:she's caught in the girls' bathroom]]. She's almost [[spoiler:DrivenToSuicide]], but when Sugiura saves her and offers to listen to her troubles, Picasso (who has been inside the sketch of her heart) rallies the class to go to where she is and listen to her. [[spoiler:When they do, they apologize for how they treated her and rally to let her wear the girls' uniform.]]
* The protagonist of ''AfterSchoolNightmare'' is intersexed, gender male. The first page in the manga has him averting NoPeriodsPeriod, much to his discomfort. [[spoiler: Later identifies as a woman.]]
* From Ludwig Kakumei, the Goose-Girl in the Well, [[spoiler: Princess Julianna, whom we know for most of the series as Lui's "step-brother" Prince Julius. She very explicitly states that she doesn't identify as a man (or almost does before she cuts herself off), despite having a male body, but everyone else seems to think of her as a crossdresser of some nature or another.]]
* In ''SorcererStabberOrphen'', we have [[spoiler: the local CoolBigSis and Orphen's first travel partner, Stephanie]]. Orphen explains to Majik and Cleao that [[spoiler: she used to be a male-bodied magic user named Stephan until few years ago, when she was seriously injured and her male body was horribly torn apart. During her recovery, she asked the healers if they could turn said male body into a female one; they accepted, and now Stephan''ie'' has a female body that she's very comfortable with.]] Cleao and Majic are rather surprised when Orphen tells them (and in fact, Cleao wonders if [[spoiler: Stephanie's boyfriend Tim]] knows), but Orphen himself seems to be pretty nonchalant about the whole deal and it's never discussed again.
* In most versions of ''GhostInTheShell'' it's implied that Major Kusanagi may have been a man before becoming a female-styled full-body cyborg, though the TV series balked at this and featured a flashback episode were she was a little girl.
* Nathan Seymore of ''TigerAndBunny'' is confirmed in [[AllThereInTheManual supplementary sources to be agendered.]]
* There's a one-shot shoujo manga called "''Go! Go! Ichigo''" about a girl who falls for her old childhood friend who came back several years later [[OldFriendNewGender a girl]].
* The protagonist of ''Manga/BokuraNoHentai'' is a transgender girl. The other two main characters are WholesomeCrossdresser's.
* Chaplin from ''DeadmanWonderland'' is transgender. The first time she used her Branch Of Sin was when she was living as a male. [[spoiler:Her lover was using her as a source of money. She got mad at the woman he was sleeping with and accidentally stabbed her.]]
* The third story in the oneshot manga ''Mascara Blues'' revolves around a trans girl who falls for a boy.
* [[spoiler:Ren's sister]] in ''Sazanami Cherry'' is revealed to be transsexual in the second to last chapter. Ren may be transsexual too but it's hard to tell.
* Mariandel from ''Anime/IxionSagaDT''.
* BC from ''Anime/{{Vandread}}''.
* Jun's mother in ''Boku to Boku'' is a trans woman.
* Alluka Zoldyck from ''HunterXHunter'' is implied to be a transgender girl. Her brother Killua, who is the only member of her family to treat her with any affection, refers to her as a girl, while her other brothers call her a boy.
* One of the protagonists of ''Manga/{{Yuureitou}}'', Tetsuo, is a transgender man.
[[/folder]]

[[folder:Comic Books]]
* In "A Game of You", a StoryArc in ''Comicbook/TheSandman'', the protagonist, Barbie, is friends with a non-operative transsexual named Wanda. [[spoiler:When Wanda dies, she shows up with Death as a woman.]]
--> '''Neighbor:''' Wanda? You've got a... thingie.
--> '''Wanda:''' Don't you know it's rude to point out a lady's shortcomings?
* In ''YTheLastMan'' [=FtM=] transsexuals are widely accepted in the post-{{Gendercide}} world as a way of avoiding SitSexuality (except by the man-hating Daughters of the Amazon who are likely to kill them on sight). The eponymous protagonist is often mistaken for one at first glance, due to [[LastOfHisKind his situation]]. Presumably genetically male MTF transgender women died when the men died because the virus specifically affected the Y chromosome, but this isn't explicitly stated.
* DC's ''Comicbook/DoomPatrol'' had a relatively short lived [=MtF=] character named Coagula (real name Kate Godwin, birth name Clark Godwin). The character was created by transsexual science fiction writer Rachel Pollack.
* Grant Morrison's ''Comicbook/TheInvisibles'' features a character called Lord Fanny who blurs the line of several types of transgenderism, her origin and things she says throughout the series suggesting that she has identified (or simultaneously identifies) as transsexual, transvestite, and drag queen. The contradictory nature of this may have been done on purpose, or more likely was sloppy research.
* Alison Bechdel's ''DykesToWatchOutFor'' started by introducing an [=MtF=] character named Jillian who hung out for a few strips. Later, an [=FtM=] character named Jerry was introduced; Lois developed a crush on him, which later moved on to a fairly durable friendship. Finally, Jasmine's child Jonas became more and more insistent about identifying as a girl, and eventually started living full-time, taking hormones, and identifying as Janis, with Lois's support.
* DTWF FollowTheLeader ''Jane's World'' has [[spoiler: Chelle's mother, a transman (so only biologically her mother). A female trucker who fell in love with him decided she was gay after learning the truth.]]
* Marisa Rahm, the lead character of MilestoneComics' ''Deathwish'' miniseries, is a realistically-portrayed [=MtF=] transsexual police detective. The series was written by Creator/MaddieBlaustein (better known as the voice of Meowth from ''Anime/{{Pokemon}}''[[note]]Dat's right![[/note]]), who was transgender herself.
* The ''Highland Laddie'' arc of ''Comicbook/TheBoys'' had a secondary character known as Big Bobby, first met in a pub wearing heels, a frock, makeup and a wig, the 6+ foot BigGuy self-identifies as a lesbian, although he was pre-op at the time. The storyline sees him emasculated by a fat psychotic lady with a pair of hedgeclippers. Bobby takes this in stride, and asks the doctors not to sew the severed genitalia back on, but to treat it as the first stage in gender-reassignment surgery. Played very sympathetically, with nary a Bridget joke in sight (initial surprise on the part of Wee Hughie, who hadn't seen Bobby for several years; Bobby is referred to by male pronouns, although not when present. There is one genital mutilation gag near the end, but one that is only slightly insensitive).
* Alisa Yeoh, a supporting character and Barbara Gordon's roommate in ''[[{{Comicbook/Batgirl 2011}} Batgirl]]'' is MTF transgender as revealed in issue 19. Though reported by multiple media outlets as "the first" transgender character in a superhero comic, author GailSimone has repeatedly stated that this is not the case, as the ''Sandman'' example and others above show.
* Sir Ystin from ''Comicbook/DemonKnights'' is some form of nonbinary gender identity, as she explains to Exoristos. The specifics of whether Ystin is FTM, intersex or something else entirely are left ambiguous.
-->I was born this way. I've kept saying, whenever anyone asks. I'm not just a man or a woman. I'm ''both''.
[[/folder]]

[[folder:Film]]
* The excellent film ''BreakfastOnPluto'', based on a novel of the same name, is all about the life of fictional Irish transsexual Kitten Braden.
* One of the most unlikely transformations is found in the 1970 film ''Myra Breckinridge'', in which ''Myron'' Breckinridge (played by film critic Rex Reed, of all people) goes under the knife and becomes Myra (played by Racquel Welch).
* Hedwig of ''Film/HedwigAndTheAngryInch'', a gay male who got the operation on the spur of the moment to qualify for a CitizenshipMarriage with his lover. Predictably, the shady doctor screwed up, and the vagina didn't form properly, leaving him/her with nothing but a urethra, the titular "angry inch", and a scar. (In RealLife, surgeons generally invert and alter the penis, so this probably would not happen.) Hedwig spends the movie dealing with essentially having become an [=MtF=] transsexual, until [[spoiler: at the end he comes, at least in the film version, to embrace a masculinity identity.]]
* ''Film/{{Transamerica}}'' is a film centering on a transsexual woman.
%%* ''Film/TheCryingGame''.
* ''Film/DifferentForGirls'' is the story of a post-op transsexual woman meeting up with her male punk friend and protector from high school, ten years later. At first, the male friend is revolted, then accepting, then aroused in the end; [[spoiler:they decide that they don't do too well apart, and become lovers. They are both unemployed, but sell the story of their relationship to a tabloid for a sick amount of money]].
* This is the whole plot of the movie ''Film/BoysDontCry'' in which a young transman uses a combination of haircut, bandages holding down his breasts and leaving his hometown to express himself properly as a man: Brandon Teena. He even manages to have sex with a girl without her noticing [[spoiler: sort of. Confusion might arise for some viewers as to whether or not Brandon was actually a transman due to his own claims that he was a hermaphrodite, but he was in a women's prison at the time and trying to keep his secret from the woman he loved, so this was pretty obviously a lie. Especially when taking into account the shower scene after his violent and traumatic rape.]]. Hilary Swank plays the role very believably.
* Bernadette in ''Film/PriscillaQueenOfTheDesert'' is a transwoman (rather than a drag queen like her two companions). One [[BerserkButton guaranteed way to make her angry]] is to call her "Ralph"...
* Judy Squires in ''BetterThanChocolate.'' She's also a singer at a local lesbian nightclub, and gets a rather tart musical number explaining the differences between drag queens and transwomen.
* ''AceVentura: Pet Detective'' features one of the less flattering parodies of ''Film/TheCryingGame'', revealing that the villain is actually [[spoiler: Lt. Lois Einhorn, who this whole time was really the missing football player Ray Finkle, having gone through complete transition (but remaining non-op), adopted the identity of a missing hiker, and became a police lieutenant, seemingly all in the sake of the perfect disguise for his revenge on the Dolphins and Marino. Roger Podacter, who was attracted to Einhorn, discovered this, finding "Captain Winkie" during a romantic encounter with her and [[UnfortunateImplications getting murdered for it]] ]]
* Tom from ''The Cement Garden'' is a boy who would rather be a girl, believing that [[WouldntHitAGirl girls wouldn't get bullied]]. His sisters eventually give him a makeover, and his best friend William takes on a new interest in him...
* The French/Belgian movie [[http://en.wikipedia.org/wiki/Ma_vie_en_rose Ma vie en rose]] ("MyLifeInPink") is a very tasteful presentation of a young [=MtF=] transsexual and her dilemmas. A possibly [=FtM=] youngster appears near the end of the movie as well.
* Noxeema from ''Film/ToWongFuThanksForEverythingJulieNewmar'' gives Chi-Chi a rundown of genderqueer types, doubling as a TheReasonYouSuckSpeech.[[note]]Noxeema's speech is obviously one person's oversimplified and subjective take. As the trope description above suggests, one could write an entire book just attempting to accurately define even ''one'' of these terms.[[/note]]
-->'''Noxeema''': When a straight man puts on a dress to get his [[FetishFuel sexual kicks]], he is a transvestite. When a man is a woman trapped in a man's body and has the little operation, he is a transsexual. When a gay man has waaay too much fashion sense for one gender, he is a DragQueen. And when a tired little Latin boy puts on a dress, he is simply a boy in a dress.
* The main character in Rainer Werner Fassbinder's film ''In a Year of 13 Moons'' is a male homosexual who gets a sex change to be more appealing to his lover. Somewhat subverted as the character did not consider himself a woman pre-surgery. This and the fact that [[spoiler:[[BuryYourGays he kills himself at the end]]]] has earned it the ire of critics who say it paints transsexuality in an inaccurate and [[UnfortunateImplications unfavorable]] light.
* ''Open'', an independent film by Jake Yuzna showed a positive same-gender relationship between a gay male pair: one cisgender, one transgender. Possibly no feature-length fiction film had shown such a relationship before.
* ''Elvis & Madonna'', a Brazilian film, is a positive depiction of a cisgender lesbian and a bisexual trans woman falling in love.
* The Thai film ''Film/BeautifulBoxer'' is a biopic about the famous male-to-female transsexual and former Muay Thai boxer, Nong Thoom. Thailand is known for its "kathoey" (literally "third gender") of male-to-female transsexuals.
* PlayedForLaughs with Stan/Loretta from ''Film/MontyPythonsLifeOfBrian''.
* There's a German film called ''Romeos'' where a gay transman falls for someone.
* The 2011 French film ''Film/{{Tomboy}}'' is about a 10 year old girl who moves to a new neighborhood and decides to live as a boy.
* ''Film/TheWorldAccordingToGarp'' features John Lithgow as Roberta Muldoon.
* German movie ''Zettl'' (SpiritualSuccessor to ''Series/KirRoyal'') has the mayor of Berlin as this. Might be a parody on the RealLife gay mayor, one of the first openly gay ones. Completely with a billionaire [[RuleThirtyFour who has a thing]] for pre-op transsexuals. And is pissed off when she finally does the operation (in the Cuban embassy, of all places) since this makes her "a totally ordinary woman!"
* Sam from ''Film/{{Gutterballs}}''. After being killed, BBK adds insult to injury by bisecting her penis to create a "mangina".
* 'Come Back To the Five and Dime, Jimmy Dean, Jimmy Dean'', the James Dean fan club reunion is joined by a stranger, Joanne, played by Karen Black, who turns out to have been better known to the rest of the club 20 years ago as Joe. Oh, and it wasn't James Dean who fathered the club president's son...
* The Chilean film ''Naomi Campbel'' is about the life of Yermen, a male-to-female woman who enters a RealityShow to get the chance to finish her reassignment therapy.
[[/folder]]

[[folder:Literature]]
* Michelle Cliff's ''No Telephone to Heaven'' has the trans/genderqueer character Harry/Harriet (also known as H/H), who is biologically male but identifies as a blend of male and female. At the beginning of the novel, s/he has a totally masculine appearance but wears bikinis, puts on feminine make-up, and occasionally dresses in the genderfuck style (for example with both a tuxedo and very campy make-up. HilarityEnsues as this impish black Jamaican character passes for an African man to fool an American tourist, who really thinks he has just met "King Badnigga of Benin!"). Towards the end of the novel, H/H [[spoiler: starts living and presumably identifying as Harriet, a white nurse, which involves double 'passing'. H/H is very aware that even as 'she' is respected as a generous nurse, s/he could literally get lynched for being trans and for passing for white, but makes this choice because a black man couldn't become a nurse]]. This character plays a huge role in the development of the very confused main character Clare Savage, a white-looking middle-class mixed-race Jamaican woman who questions the racist standards of her formerly slave-owning family and might further be bisexual. His/her ability to transcend social binaries and to fool racists and homophobes/transphobes is part of his/her attributes as a {{Trickster}} figure.
* Zoe Marriott's ''Shadows on the Moon'' has [[spoiler: Akira]] who was born male but who identifies as female. When [[spoiler: she became the Shadow Bride]] she should have been killed when her sex was revealed, but [[spoiler: the prince understood and described her as having a female heart.]]
* David Thomas's ''Girl'' is about Bradley, a macho, working class, rugby playing young man who accidentally goes through sexual reassignment surgery (and simultaneous breast augmentation) through a hospital error. It is actually quite sensitive and sweet, even if it is a bit of a stretch that the (almost stereotypically) blokish Bradley decides to commit himself to becoming a woman so quickly, ending up as a sweet-natured, pretty (thanks to hormones and plastic surgery) and content young woman named Jackie.
* In LoisMcMasterBujold's ''[[Literature/VorkosiganSaga A Civil Campaign]]'', the dashing and unconventional Lady Donna Vorrutyer undergoes gender reassignment at age 40 to become Lord Dono. As this is SF, Lord Dono's transformation is perfect - he's even fertile. Lady Donna chooses this course so that she can prevent a corrupt male relative from inheriting her dead brother's countship and its attendant responsibilities. Barrayaran law doesn't allow women to inherit countships, but neither is it exactly set up to deal with transsexuals - in the end [[spoiler: Dono prevails]]. And ends up engaged to be married. One assumes Donna was originally bisexual. Elsewhere in the Vorkosigan series, it's stated that people who choose to have their brains transferred to younger clones often choose to change sex when they do. How you can have a [[OppositeSexClone clone of the opposite sex]] isn't explained.
** Judging by what happened with [[spoiler: Mark Vorkosigan]], I would say that they do it by making a normal same-gender clone and then giving it a sex change like Lord Dono's. The result would apparently be indistinguishable from a real OppositeSexClone.
* [[spoiler: Commander Ambrose]] in Maria V. Snyder's ''Study'' trilogy. [[spoiler: As it turns out, the Commander has both a female and male personality within a female-gendered body due to magic -- his mother died giving birth to him and her spirit entered his body (and apparently changed his genitalia). The female personality is allowed out whenever the Commander leaves the country, and is officially an ambassador.]]
* Creator/AngelaCarter's ''Literature/ThePassionOfNewEve'' (1977) is a novel about a British man, Evelyn, who is, well, ''castrated by MilitantFeminists'' and made into "a New Eve". It's a satire on Feminism in general, Freudianism, and all other sorts of things. Also features a Dystopic America in the process of caving in on itself.
* [[http://www.strangehorizons.com/2009/20090302/diana_comet-f.shtml Diana]] [[http://www.strangehorizons.com/2009/20090309/diana_comet-f.shtml Comet]]
* Coydt Van Haaz, the women-hating BigBad of JackChalker's ''Empires of Flux & Anchor'', turns out to be an [=FtM=] transsexual with a very tragic BackStory. [[spoiler: Turns out he was biologically male originally, until he was castrated and then given an involuntary (and irreversible) [=MtF=] GenderBender as a teen. He wants his manhood back and he wants it bad. Since that's not possible he wants to make all women suffer for what happened to him.]] This is very unusual in a 'verse where [[EasySexChange Easy Sex Changes]] are canon.
* In Creator/JohnVarley's ''Literature/EightWorlds'' series, sex changes have become so easy and common that anyone who goes through their entire lives as the same sex is considered a little weird, and population control laws have boiled down to "one person, one child."
* In an odd twist, Gurgeh (from ''Literature/ThePlayerOfGames'' by [[Creator/IainBanks Iain M. Banks]]) is regarded as being a bit odd because, although changing sex is the norm for most (human) citizens of the Culture, he has never done so. The strong implication is that Gurgeh regards everything as a game and at some level regards being a receptive sexual partner as ''losing''. At the start of the book, it's mentioned that a distinct majority (six in ten?) of his ex-lovers have become, and stayed, [=FtM=].
* Lady Dela from Alison Goodman's fantasy ''Eon: Dragoneye Reborn'' is a played straight and rather awesome version of this trope. The varied views of prejudice and acceptance surrounding her are also interesting, as the people of the Asian-inspired universe of the book seem to regard her either with respect for being a sacred "twin-soul", or a freak because they think she's a man living as a woman.
* ''Literature/{{Luna}}'' by Creator/JulieAnnePeters is about an [=MtF=] transsexual's teenage sister, Regan. Regan often has to lend Luna clothes or cover up for her, because their parents do not know.
* ''Parrotfish'' by Ellen Wittlinger is about an [=FtM=] transsexual, Grady Katz-[=McNair=]. At the beginning of the book, Grady decides he wants to officially come out and change his name from Angela to Grady. The title of the book comes from his nerdy friend, who points out that female parrotfish often change to males.
* Neil Gaiman's short story ''Changes'' concerns the accidental creation of a drug that allows an EasySexChange and the ramifications of said drug on the global society. Gender identities are blurred as the drug takes on a recreational use, and in the end (as with every conflict of generations) it's seen as something ordinary (if mildly dirty) by the young and disgusting by the old.
* David Nobbs's ''Sex and Other Changes'' is about a transsexual married couple, both of whom transition in the course of the novel.
* [[spoiler: Anna Madrigal]] from Armistead Maupin's ''TalesOfTheCity'' and its sequels, along with the television mini-series adaptations.
* A character in Tamora Pierce's book Bloodhound is a male-to-female transsexual called Okha/Amber. In that world, it's apparently referred to as being 'tapped in the womb by the Trickster God'.
* ''Literature/TheBonePalace'' by Creator/AmandaDownum has Savedra Severos, the transsexual mistress of the Crown Prince, as its second viewpoint character. Transsexuality is only marginally accepted in this culture; it has a long history in the open, but most ''hijra'' (the "third sex", encompassing all varieties of transgender and agender people) live apart in the company of their own. Most are either in the priesthood, are mystics and fortune-tellers, or work in prostitution. Savedra is lucky; she was born wealthy and her mother and family members accept her. Despite the magic of the setting, nothing seems to give any kind of EasySexChange; Savedra at one point laments her Adam's apple and her small breasts, and she retains functional male genitalia, so physical sex reassignment does not appear to be possible.
* One novel -- about a yuppie Latina in San Francisco working under the mayor's wife -- features an [=MtF=] transsexual as a supporting character. She met her boyfriend in a gay men's dance troupe, meaning the author sadly missed the part about gays and transsexuals not being one and the same.
* There's a children's book named ''10000 Dresses'', by Marcus Ewert and Rex Ray, about a young [=MtF=] who wants to wear dresses but isn't accepted by her parents.
* The excellent novel by David Ebershoff called ''The Danish Girl'' is a fictionalized account of the first widely publicized gender reassignment surgery ever performed. The subject of the novel, Einar Wegener, begins to confront his body and sexuality issues after being asked by his wife to pose in a dress so that she may finish a commissioned portrait of a friend of the young couple. Einar is then moved by this experience to begin identifying himself as Lili. The novel explores the situations of both Lili and the ever-loving and supportive Greta as they come to terms with Lili's transformation. A film adapation allegedly staring Nicole Kidman as Einar Wegener/Lili is currently in DevelopmentHell.
* The title character from ''I Am J'' by Cris Beam, a Jewish, Puerto Rican, [=FtM=] teenager who is deeply insulted by being called a lesbian, or even by his confused parents calling him "my daughter".
* In Brian Katcher's ''AlmostPerfect'', the main character meets, and falls in love with [[NewTransferStudent the new girl]], who happens to be MtF. He struggles to accept her, and eventually does so in a well thought-out manner, based in part on the author's interviews with young transgender people.
* Isabel Allende's ''Literature/EvaLuna'' has Melecio, an Italian teacher who ever since young identified as a girl, much to the ire of her [[AbusiveParents abusive father.]] Her ''Mamma'' [[OpenMindedParent supports them devotedly]], though, and she get some solace in her {{Inter generational friendship}}s with [[MissKitty La Seńora]] and [[PluckyGirl Eva]]. [[spoiler: When Eva returns to the capital after spending several years in a small village, she finds out that after a full-blown BreakTheCutie process (which included politically-based incarceration, rape, torture, illness and many other terrible things), Melecio now openly can identify as female and [[MeaningfulRename has renamed herself as Mimi]]. She's still working on rebuilding her life alongside going through reassignment therapy by that time; after the meeting, she pretty much adopts Eva into her household as they retake their InterGenerationalFriendship, then with time [[EarnYourHappyEnding she both becomes a TV star AND finds the love of her life.]] When Eva gets her the chance to go through the final operation, however, Mimi rejects it: she's squicked out by the surgery in itself ''and'' she doesn't think it's necessary, as her boyfriend (the local DaEditor Aravena) loves her the way just she is.]]
* ''[=F2M=]: The Boy Within'' by Hazel Edwards and Ryan Kennedy is about a [=FtM=] teenage boy named Finn. He's also a part of a punk rock band called "Chronic Cramps".
* There's a children's book called ''When Kathy is Keith'' by Dr. Wallace Wong, who works with transgender youth. It's about a trans boy named Kathy who no one believes is really a boy.
* [[Creator/HarukiMurakami Murakami's]] ''KafkaOnTheShore'' has Oshima, a gay trans man.
* Eriko from Banana Yoshimoto's ''Kitchen''. The main character, Mikage Sakurai, stays in her and her son Yuichi's house after the death of the dear grandmother [[RaisedByGrandparents who raised her]].
* Literature/WhenItHappensToYou features a transgirl named Olivia/Oliver as a major secondary character.
* Recently revealed to be the case for [[spoiler: The Princess]] in Literature/VelveteenVs via origin story.
* In Literature/PureAgain by Kevin [=McGowan=], two transsexual characters undergo a voluntary FreakyFridayFlip.
* In the second book of the ''Literature/OutlanderLeander'' series, Valli is an [=FtM=] transsexual. Notably, he wears dresses and is considered beautiful, but these traits aren't considered feminine in their culture. Valli is accepted as a man without question.
[[/folder]]

[[folder:Live Action TV]]
* Very much PlayedForLaughs by Barbara Dixon, the grotesque taxi-driver of Royston Vasey in LeagueOfGentlemen
* ''NipTuck'' seems to have a bit of a fascination with transsexuality (understandably, as the show is largely concerned with sex and plastic surgery); the most notable of these is Ava Moore (played by Famke Janssen), whom main character Christian calls "the goddamn Hope Diamond of transsexuals."
* ''The Education Of Max Bickford'' had a reasonably realistic transsexual character for its first season or so, who was an old school chum of Max's.
** It only ran one season; the show's creators were fired by the network halfway through its run, and the transwoman (well played by Helen Shaver) was never again seen.
* ''CoronationStreet'' has a realistic and extremely sympathetic transsexual woman, whose marriage to another long-time regular character was one of the highlights of recent seasons.
* ''AllMyChildren'' has introduced a transsexual character in the process of transitioning. Is in a relationship with a lesbian.
* ''TheLWord'' has had a drag king as a recurring character, and a transsexual man as a member of the main cast.
* ''UglyBetty'' has Alexis Meade, who lives as a woman after faking her death. Of course, [[UnsettlingGenderReveal her brother didn't know]] until [[BrotherSisterIncest after he starts hitting on her]]...
** In a later episode in which Daniel is displeased by his long-lost half-brother:
--->'''Daniel''': Don't call him my brother. [[http://www.movieweb.com/tv/TEKd3KNNINpTOR/my-only-brother-is-my-sister My only brother is my sister, Alexis.]]
* One of the reasons why the Argentinian telenovela ''Los Roldán'' was so succesful? The fun-loving transsexual character played by actress Florencia de la V, who ''is'' a male-to-female transsexual in [[TruthInTelevision Real Life]].
* ''Series/TwoAndAHalfMen''
** In season 1, Evelyn's new boyfriend turns out to be one of Charlie's old girlfriends. Once the obligatory torrent of puerile jokes are through, the episode is surprisingly sensitive.
** In season 11, Alan dates a transwoman briefly. Her treatment is very sensitive, save a few light-hearted jabs in the form of residue pre-transition behaviour (paying for him on a date, giving him her jacket, punching an obnoxious man being mean to him, and [[BreadEggsMilkSquick scratching her ‘phantom nuts’]]), which Alan doesn’t mind or even enjoys. In a surprising twist, [[spoiler:their relationship ends when she gets back together with her ex-wife, at Alan’s surprisingly selfless encouragement. (Although [[GirlOnGirlIsHot he does get a kick of watching them reconcile]].)]]
* One episode of ''Series/TalesFromTheCrypt'' ("The Assassin") had a team of government assassins invade the home of a very stereotypical suburban {{Housewife}} because they're convinced her husband is a rogue former agent who used MagicPlasticSurgery to radically alter his appearance before going underground. Nothing she says can convince them otherwise so she turns the tables on them and easily kills them all. It turns out ''she'' was their rogue former agent after quite a bit more [[EasySexChange plastic surgery]] than even they had been prepared to believe.
--> '''Female Agent''': Does he still like it rough?
--> '''Housewife''': Yes, as a matter of fact, I do.
** This is also the twist of a later episode, "Last Respects", where a female lawyer hired by a dying rich man turns out to be the man's long-lost son. Her father doesn't learn this until after he attempts to seduce her, prompting her to disrobe for him.
* The victim in one episode of ''{{Bones}}'' turns out to be a postoperative transsexual woman. This is handled with surprising sensitivity, and despite the title of the episode that status is ''not'' the focus of the plot.
* An episode of ''NightCourt'' had an old university friend of Dan Fielding show up as a post-op [=MtF=] transsexual, in the process of getting married; with Dan naturally playing the role of rabid homo/transphobe. The show being what it was, this was mostly played for laughs; but also a CrowningMomentOfHeartwarming as well.
* ''Series/DoctorWho'' examples:
** Cassandra from the "The End Of The World" and "New Earth" is a trans woman. She's also thousands of years old and had so much plastic surgery that she's now only a face on a ''very'' thin layer of skin [[spoiler: or at least until she begins to possess Rose's, the Doctor's and ultimately her caretaker's bodies]], so being trans is one of the ''least'' notable things about her.
** "A Town Called Mercy" features a [[ItMakesSenseInContext transsexual horse.]] His name is Susan and he would like you to respect his life choices.
* Mark in ''AllyMcBeal'' found out that his girlfriend (played by the lovely Lisa Edelstein) was a [=MtF=] pre-op transsexual. They tried to make it work anyway, but he was just too freaked out.
* In an episode of ''StElsewhere,'' one of Dr. Craig's old pals shows up at the hospital. All goes well until he happens to mention that he's having sexual reassignment surgery. After having a trademark freakout for most of the episode, Craig finally accepts the situation.
* One episode of ''TheSarahConnorChronicles'' features Sarah searching for a man on the run from Skynet, only to find out he's been hiding his identity by living as a woman. None of this is played for laughs, and with zero amount of freaking out or any talk about sex. Alan/Eileen later admits to being strangely grateful for the opportunity to live as her true self, despite being hunted.
* In one episode of ''RabCNesbitt'' a new barmaid at Rab's local pub is a pre-op [=MtF=] transsexual (played by David Tennant, no less!). At the end of the episode she helps Rab and Mary to get revenge on Mary's extremely sleazy new boss (who has been sexually harrassing her from her first day in the job) by taking Mary's place at work one day and seducing him in the broom cupboard, leading to a spectacularly horrified reaction when he discovers certain unexpected items...
* ''LawAndOrderSpecialVictimsUnit'' examples:
** In one episode, the VictimOfTheWeek, Cheryl (played by [[{{thelword}} Kate Moennig]]), is on trial for beating a man to death. As the investigation continues, it's discovered that she is a pre-op transsexual woman, and she acted in self defense. Long story short, she was put in a men's prison, and after her trial, [[spoiler: she is gang-raped]].
** "Transitions" involved a pre-teen transwoman whose father refuses to let her start hormone therapy and transition. The episode treats the young girl quite sensitively, with most characters accepting and using her preferred identity and her father eventually coming around (even after being brutally attacked.)
* An episode of ''Series/{{CSI}}'' featured a well-intentioned doctor who did back-alley sex-change operations. It also revealed that some show girls weren't born girls.
** In another ''CSI'' episode, the victim was a pre-op transsexual woman, killed by an actor after he goes to bed with her, discovers her sexual identity and freaks out about the fact damaging his carreer. It ended with Grissom saying:
-->There's an old rule of showbusiness that says 'Never be caught with a dead woman or a live man. He was caught with both.'
** A similar case happens in CSINewYork, where a [=MtF=] transsexual (who was still transitioning) is found dead in the men's toilets of a very posh hotel that happened to have been running a political rally/party at the time. The initial suspect was a governor who had raped the woman's sister, but the murderer was actually a man who she'd made out with earlier that evening - finding out that she was biologically a man enraged him (made worse by the fact that his friends knew, and found it hilarious that he'd kissed a man), and he flipped out when he saw that she was using the men's room "like a normal man".
* Two episodes (that I recall) of ''{{NCIS}}'' had transsexual characters. One became a (brief) running joke after Tony made out with her, and whilst the subject wasn't dealt with insensitively, it wasn't amazing either. The other was a character who was dead by the time the episode really began (suicide), and was dealt with a lot better, even if there was the obligatory "he... she... he-she" moment.
* An episode of ''Series/TheListener'', "Lisa Says," had a transsexual character. Well dealt with and reasonably unusual because the character was [=FtM=].
* Inverted on ''WillAndGrace''. Jack (a gay man) finds himself sexually aroused by a female stripper giving him a lap dance and starts to question his existence, but is relieved to find out that she is a ''pre-op'' transsexual and he was just aroused by the feeling of her penis.
* Adam in ''Series/DegrassiTheNextGeneration'' is introduced as a NewTransferStudent, and we find out his secret at the same time as everyone in the school does. His grandmother still doesn't know. As a bonus, the character also has the title of the first fictional, transgender, teenaged character in the history of scripted television.
** However TrailersAlwaysSpoil, this was heavily hinted in the promo for Season 10 to be the case. The one thing that did help matters, the actress playing Adam is named [[GenderBlenderName Jordan]] Todosey. So the opening credits didn't also spoil, [[OnlySoManyCanadianActors unless you have seen]] [[LifeWithDerek other Canadian teen shows]].
* In the French-Canadian series ''Un Gars Une Fille'', Guy and Sylvie participate in a gay pride parade alongside Guy's lesbian half-sister. There, they encounter an old high school hockey teammate of Guy's, who has transitioned into a woman. A humorous line happens when Sylvie asks her if it was a difficult process.
-->"Yes it was, and it took a lot of balls... ''which I no longer have!''"
* Jasmine/Jason of ''Series/{{HollyOaks}}'' is an [=FtM=] transexual...whose male side gets framed for murder by a PsychoLesbian so ''he'' has to carry on living as a girl. It's...complicated.
* The episode "Boy Crazy" in ''Series/ColdCase'' features a young [=FtM=] transsexual in the 1960's murdered for dressing and acting like a boy.
* An episode of ''{{ER}}'' called "Next Of Kin" stars a child named Morgan. The episode doesn't [[DownerEnding end well,]] since she's forced to live like a boy after moving in with her mom when her dad dies; apparently due to the fact her step-dad would not accept her as a girl.
* One of the dozens of subplots in ''Series/DirtySexyMoney'' revolves around Patrick Darling's relationship with a post-op transsexual woman named Carmelita, which he attempts to maintain despite (a) being married to someone else and (b) running for the U.S. Senate.
* One episode of ''DarkAngel'' has Jam Pony's resident square Normal get into a relationship with a transsexual woman. When he finds out, he's still quite willing to go out with her, but she dumps him and expresses interest in resident lesbian Original Cindy, who is repulsed.
* Mrs. Hudson from ''Series/{{Elementary}}''. Interestingly, little has been made of it -- she hasn't been treated differently, joked about, or anything really.
* Nao, a character introduced in season 6, from ''3-Nen B-Gumi Kinpachi-sensei'' was revealed to be trans. He was introduced in a similar manner to Adam from Degrassi, though he was pre-transition.
* Tony, introduced in episode 2.08 of ''Series/OrphanBlack'', was assigned female at birth but identifies as male and has begun transitioning.
* Sophia Burset in ''Series/OrangeIsTheNewBlack'', who's in prison because when she was a firefighter she stole credit cards and financial information from burnt houses, to pay for hormones and surgery. Despite being a secondary character the show attracted wide praise for having one of the most sympathetic portrayals of a trans woman in film or television history, and her actress Laverne Cox (a trans woman in real life) has used the publicity to further her campaigns for the rights of transgender people.
* In a weekly-aired Chilean RealityShow about plastic surgery, one of the participants was a trans woman named Alejandra who entered it hoping to get the reassignment surgery. She won that round and was succesfully operated on.
[[/folder]]

[[folder:Music]]
* Music/SuzanneVega song "As Girls Go" about a male to female transsexual.
* Music/TheCliks are the first band with a trans frontman to be signed to a major label. Apparently their leader, Luacs Silveira, abstained from testosterone injections to preserve his singing voice.
* The Music/VelvetUnderground's "Lady Godiva's Operation," focusing on an [=MtF=] transsexual first going under the knife. [[BuryYourGays Things don't really work out.]]
* Dolly Parton's "Travelin' Thru" was written with the process of transition in mind. It is played at the credits of the movie ''Transamerica''.
* The appropriately named ''Music/{{Scorpions}}'' hit "He's A Woman, She's A Man".
* The most common interpretation of the song "For Today I Am A Boy" by Antony & The Johnsons is that it's about a transgender person. The songs "You Are My Sister" and "I Fell In Love With A Dead Boy" have the same interpretations.
* Punk band AgainstMe! announced in February 2012 they were recording a new album. Fast-forward to May and the album's title is released: ''Transgender Dysphoria Blues''... along with news that their lead singer is also transgender.
* UTAUloid/Vipperloid Yokune Ruko is an intersex chimera of 90% male/10% female, according to his/her creator. Due to Ruko's very feminine appearance (as well as her expansive bust), many fans (and sadly, as a result, FanDumb) treat the 'loid as female for the purposes of non-sexualised fan works ... despite the fact that the ''whole point'' of him/her is that they have '''both a male and a female voicebank''.
* Anna-Varney of Music/SoporAeternusAndTheEnsembleOfShadows is a MtF transsexual, but refuses to get hormone treatment or surgery because of "spiritual conflict" resulting from such.
* SteamPoweredGiraffe technically contains two transgender performers in the form of Bunny Bennett, a transwoman, and her onstage persona, Rabbit (originally a male robot [[RealLifeWritesThePlot whose gender was changed to match Bunny's own]]; Rabbit's status as a robot and subsequent lack of any real gender makes this debatable).
* Schmekel is an all-transgender, Jewish folk punk band from Brooklyn, NY, featuring four transmen.
[[/folder]]

[[folder:Pornography]]
* The trope is [[RuleThirtyFour extremely common in porn]], but, [[MostWritersAreMale being]] [[AllMenArePerverts porn]], nearly always the character is portrayed as male-to-female transsexual, having a fully female identity, a pre-operated body (keeping the fully functional genitalia), [[AllWomenAreLustful a lusty disposition]] and ability to have sex in either form with males, females [[AnythingThatMoves and everything else]]. Which would be fine on screen and raise plenty of UnfortunateImplications in RealLife - and not only the brutal kind of homophobic or transphobic UnfortunateImplications people would imagine at first glance, but also plenty of unwanted attention from those who believe in the [[AllWomenAreLustful idea of a perpetual lusty creature]].
** Queer porn is becoming more popular, and with it female-assigned-at-birth genderqueer individuals and female-to-male transsexuals are becoming more apparent.
[[/folder]]

[[folder:Tabletop Games]]
* ''TabletopGame/{{Exalted}}'' has two examples. The Tya are woman in the West, who after getting intricate tattoos and drinking a tonic that sterilizes them, are legally considered males, and can sail without fear of Storm Mothers, who destroy any ship that has a woman more beautiful then them, which includes pretty much any woman. The Dereth are Delzhan who wear a special gray sash and are legally and culturally recognized as the opposite gender.
** The Lunar Exalt Silver Python is agender. As a form of homage to Luna, who's associated with gender fluidity, zhe regularly switches genders every twenty years, and no longer remembers or cares which zhe started out as.
* Of all franchises, the ''VideoGame/WorldOfWarcraft'' [[TabletopGame/WarcraftTheRoleplayingGame Tabletop RPG]] actually touched on this one, by explaining how quilboar- a race of warthog-like humanoids, who are AlwaysChaoticEvil in the MMO but are given a somewhat more sympathetic portrayal in the tabletop game- operate under a strict StayInTheKitchen rule, but if a female proves herself to be a strong and capable warrior, then she is declared to be a male by the tribe's shaman, and will live as a male and even take wives from that point forward.
* ''TabletopGame/{{Pathfinder}}'', due to not being hampered by the "decency codes" that constrain ''TabletopGame/DungeonsAndDragons'', freely embraces a more adult stance on things and so openly includes homosexuality and transsexuality in its setting, something that has given the game a notable LGBTFandom. Transsexual and gender-neutral characters are quite common through the game books, including such figures as the androgynous angelic Empyreal Lord[[note]]lesser god of NeutralGood[[/note]] Arshea, whose portfolio covers freedom, physical beauty and sexuality, and whose gender ambiguity means that all individuals, regardless of gender or personal sexuality, find him-her to be ravishingly beautiful and sexually enticing.
[[/folder]]

[[folder:Theater]]
* Sweetie in ''BombayDreams'', a beautiful transwoman who [[IWantMyBelovedToBeHappy just wants her childhood friend and longtime crush Akaash to live his dreams and get what he wants]], to the point of eventually performing a HeroicSacrifice.
* As mentioned above, Angel from ''{{RENT}}''.
[[/folder]]

[[folder:Video Games]]
* In ''{{Persona 3}}'', during "Operation Babe Hunt" Junpei, Akihiko, and your protagonist are victims of UnsettlingGenderReveal when the only woman who actually is interested in you three seems rather suspiciously eager and vulgar minded. The reveal is when [[spoiler: Akihiko realizes she has some hair on her chin and she outs herself, and given how disappointed she was that you figured out "her" secret, and that she wanted you guys as "boytoys" anyway, this actually is a a case of TransEqualsGay being correct.]]
* {{Subverted|Trope}} in ''VideoGame/{{Persona 4}}'' with [[spoiler: Naoto. She appears to be this at first, given her Shadow's actions and intentions, but it turns out she's simply trying desparately to be accepted in the very male-dominated line of work she's in. All of her detective heroes as a kid were male, and all of her co-workers are male, so she viewed those as role models, and aspired to be just like them, unfortunately causing her to believe she had to become male - not unwarranted, given how misogynistic Japanese men can be in such occupations.]]
** That said, it is quite common for some sects of the fandom to [[spoiler:[[AlternativeCharacterInterpretation hypothesize that]] Naoto may have been trans all along (without realizing it or having come to terms with it in-game), or at the very least [[WhatIf create an alternate scenario apart from established canon in which Naoto ''was'' trans]]. Explanations for the fan's alternative interpretation vary. For example, some fans reason that Naoto still seems uncomfortable with femininity even after having been "outed", some fans believe it to be farfetched that anyone would be able to go through willingly hiding their own gender for their whole life simply because of the gender of their role models, [[http://www.gamespot.com/articles/denial-of-the-self-queer-characters-in-persona-4/1100-6404712/ some believe the revelation of Naoto having been "not trans after all" to have been a cop out from a potentially intriguing narrative that offered queer representation]], and some fans are simply transsexual themselves and identify highly with Naoto's experiences. The reasons are different for each supporter of this interpretation. The issue is unfortunately a huge a BaseBreaker among the Persona 4 fandom, because fights break out easily when one side of the faction tries to force their stance on the other.]]
* Poison and Roxy from ''FinalFight'', both male-to-female. They [[{{Bowdlerise}} didn't make it]] Stateside in the console versions, though (thank you very much, [[CensorshipBureau Nintendo Standards and Practices]]). In fact, Poison doesn't reappear until ''Final Fight Revenge''. From that point forward, she sticks around as Hugo Andore's manager/bodyguard/bickering best friend, i.e. that's how we see her in ''Street Fighter III''.
** The amusing fact is that this whole situation actually arose out of [[GettingCrapPastTheRadar trying to prevent censorship.]] Capcom of Japan knew that it was not kosher to depict violence against women - [[CriticalResearchFailure so their excuse was that the characters weren't born as women in the first place]]. They have gone further on record that Poison's status is post-op in America and pre-op in Japan.
*** The FridgeHorror at work here is that it's not okay to hit a woman, but it's perfectly acceptable to hit a transsexual.
** (As [[http://kotaku.com/5888814/a-twenty+minute-documentary-about-the-gender-of-final-fights-poison this]] in-depth documentary points out,) Poison and Roxy are both labeled as "newhalf" in their concept art and Poison has the term in the original Japanese instruction booklets for the first two games in the series. As the booklet came out two years in Japan before it hit Stateside, it is unlikely that Capcom made this change simply to accommodate Nintendo. While Capcom may not have considered them to be women, they were still "newhalves" from the very beginning.
*** Newhalf, for the unfamiliar, is a Japanese form of "realistic" {{hermaphrodite}}, having a female body-structure and features but male sexual organs.
* Another example of the term "newhalf" appearing in videogames is the Frozen Half, an ice magician described as such in ''VideoGame/CastlevaniaSymphonyOfTheNight''. The ''Dracula X Chronicles'' rerelease changed the term to "transvestite". In both games the enemy is described as serving Galamoth, and it indeed first appeared in ''VideoGame/KidDracula'', though wearing ice skates and [[{{Gonk}} looking far less convincing]].
* Perhaps the most famous video game example is [[{{Mario}} Birdo]], who was described in the [[AllThereInTheManual manual of her first appearance]] as "wanting to be called Birdetta" and "wanting to be a girl". Although she started as a crossdressing male, more recent appearances have hinted (CaptainRainbow provided more concrete... evidence) that she has since had "the operation", and transitioned to a female body.
* [[VideoGame/{{Mother3}}The Magypsies]] ''look'' like this. They actually have no real gender.
* It's slightly ambiguous, but [[spoiler: Robin]] of ''Videogame/CuteKnightKingdom'' appears to be transgender female-to-male.
* Examples from VideoGame/DeptHeaven's "Union" games:
** LethalJokeCharacter Eater from ''VideoGame/BlazeUnion'' has two personalities, one of which is male. Eater is biologically female, but when the male half is in control, he is treated by all other characters and by the game system itself (which has different unit formations based on gender) as a man who just so happens to be running around in the girly clothes his other personality put on in the morning.
** ''GloriaUnion'' has Kyra, who identifies (and is treated by the game's system itself) as intergender.
* [[spoiler: Erica, formerly Eric]] in ''{{Catherine}}''. Notably, TheReveal is not treated as anything especially dramatic - it's mentioned rather nonchalantly in the Lovers True Ending, [[spoiler: Toby]] is happily in a relationship with [[spoiler: her]] (or at least one with a lot of mutual snarking), and Vincent, Johnny, and Orlando knew all along as he went to high school with [[spoiler: her]]. In hindsight, there's a lot of foreshadowing for it.
* Played for laughs in ''VideoGame/DragonAgeOrigins'' and slightly less in ''VideoGame/DragonAgeII''. In the former, at the Pearl, the PC has the option of saying "surprise me" and getting a very obviously male dwarf prostitute in a female costume. In the latter, at the Blooming Rose, the transgender elven prostitute at least has a female body model even if her voice is male.
-->'''Husky Dwarf:''' I've got a little something for everybody.
** There were transgender elven prostitutes in ''Origins'' as well, with such lines as "You have to slay the dragon before you can get to the princess". Also, the "surprise me" option can lead to a whole number of encounters, from the crossdressing dwarf to a room full of nugs- think a pig crossed with a naked mole-rat.
** In the comic series that stars Alistair, Varric and Isabela, Maevaris, a Tevinter Magister who's the former lover of Varric's cousin is later revealed to be transgendered after she's found in the dungeons. Other than that, her gender doesn't play into the story in any way,
* Subaru Kujou in the fifth ''SakuraTaisen'' game is pretty clearly genderqueer; zie always uses gender-neutral speech (at least in the Japanese version), refuses to identify as male or female, and dresses in both masculine and feminine attire.
* ''VideoGame/PokemonXAndY'' has one "Beauty" trainer from Battle Tower mention: "Yes, a mere half year ago I was a Black Belt! Quite the transformation, wouldn't you say?" Black Belts are a type of trainer consisting exclusively of men (as opposed to their {{Distaff Counterpart}}s, Battle Girls), suggesting this particular Beauty underwent gender reassignment surgery. The Japanese version of the game is less ambiguous: The Black Belts' Japanese name, Karateoh, translates into "Karate Kings"; and the Beauty makes mention of "modern medicine".
* Jean Armstrong from "Recipe for Turnabout," the third case of ''[[VisualNovel/AceAttorney Phoenix Wright: Ace Attorney: Trials and Tribulations]]'' is an unusual case in that he is a very masculine man physically (is burly and has FACIAL HAIR), but has a very effeminate character and identifies himself as a woman on multiple occasions.
** Another character in ''VisualNovel/PhoenixWrightAceAttorneyDualDestinies'' is viewed as one gender and acts like that specific gender, but is revealed to be the total opposite. [[spoiler: Robin Newman, the extremely loud, angry, and passionate boy is actually a girl. Robin was born as a girl, but her parents raised her as a boy since birth and she had to wear a strap on her chest to hide her breasts. Once Robin comes to terms with this, she starts acting more girly - likely because she's now free to try more feminine things, after a whole lifetime of having been denied to do so.]]
[[/folder]]

[[folder:Visual Novels]]
* [[spoiler:Kaine]] in ''VisualNovel/AProfile''. It's handled pretty tactfully and pointed out that it makes things pretty difficult for him. He reacts poorly to the issue when it is mentioned. However, despite mostly being handled well there appears to have been some confusion on the part of the writers between this and [[TransEqualsGay homosexuality]]. Though it ''may'' just be his own inadequate understanding of the issue and that Kaine simply happens to also be attracted to women. [[spoiler:Kaine is biologically female, however, but never felt like one. So he/she started going to school in male clothing and took male hormones to be more masculine. Despite being transsexual, Kaine continues to be treated as a male. He gets more female attention than Masayuki despite being pretty open about it.]]
* Jun Watarase in ''VisualNovel/{{Happiness}}'' is implied to be this. Although initially seen as a common trap or as a WholesomeCrossdresser, the OVA in particular shows Jun overjoyed when accidentally actually turning female (of course, [[StatusQuoIsGod before the end of the episode]]).
* The whole story is complicated, but in the end it boils down that [[spoiler:Princess Cassidy]] in ''VisualNovel/TheRoyalTrap'' is probably this rather than intersex. [[spoiler: She was [[RaisedAsTheOppositeGender raised as a girl]] since she was a toddler and never knowingly wanted to be anything else.]]
[[/folder]]

[[folder:Webcomics]]
* QuestionableContent has at least two; Claire, the MtF character who has appeared lately, and Tai the lesbian librarian who apparently had a phase of "identifying as a boy" ( binding her breasts, "wearing lots of Carhartt stuff" etc ) but now seems settled as a lesbian, somewhat tomboyish with her short hair but following the same t-shirt and jeans dress code as the rest of them - Claire is about the only character to consistently wear a skirt, apart from Marten's mother.
* ''Webcomic/TheOrderOfTheStick'': Vaarsuvius is often cited as the most prominent trans character in webcomics, although zir gender is entirely unknown. Although zir trans status started out as a RunningGag, it seems that V (and zir mate) identifies as agender or that certain elves don't prescribe to gender binaries like most humans.
* ''Webcomic/VenusEnvy'' is all about a male-to-female transsexual teenager, who, at the beginning of the comic, has recently switched schools as she moves to living as a full-time female. She also has a friend the same age who is a transitioning [=FtM=] transsexual too.
* One of the lead characters in ''Closetspace'' is a transgender woman, who struggled with the decision of whether to undergo SRS, later regretting the surgery, but retaining her female identity. The other lead is also transgender, just starting her life as a woman.
* The main subject of ''Webcomic/TransGirlDiaries'' as it involves a main cast of transsexual characters. Also its fan sequel to ''Webcomic/VenusEnvy'', "This is Your Life."
* In Jennifer Diane Reitz' series ''Webcomic/UnicornJelly'', Wai Wai Ngo is eventually revealed to be a transgender man. This is a serious issue, as gender deviation is punished by death in the society of the time, and furthermore, this is discovered at a point AfterTheEnd when [[DeusSexMachina everyone is obligated to have children]] due to the small surviving gene pool. In the AlternateUniverse series ''To Save Her'', we see a younger Wai struggling to get his father to recognize him as male; later, during their travels, he is given sex-reassignment surgery to become fully male (the medical science in the Splay they went to being highly advanced).
* ''[[http://nxsinxmcosxoxsq.livejournal.com/ Katie Lynne Sapphe: The Webcomic]]'' is a very irregularly updated DiaryComic by a transsexual woman going through transition as a college student.
* Tom and Charlie from ''Webcomic/KhaosKomix'' Tom being a [=FtM=] and Charlie being a [=MtF=]. The author also identifies as "Trans".
* Natani of ''Webcomic/TwoKinds'' went from merely wishing she was male (instead of just pretending, due to her profession as an assassin) to actively believing it (due to her soul being merged with her brother's in order to save her from a dark curse). Though Natani lets her brother refer to her as "Sis" with minimal grumbling. Whether Natani counts as a "true" transsexual or is just a self-loathing misogynist is probably deliberately left open.
* Minor character Riley from ''Webcomic/ErrantStory'' is intersexed, which has caused [[http://www.errantstory.com/2006-11-15/586 chaos]] at least once.
* Ash from ''Webcomic/{{Misfile}}'' acts more like a genuinely transgender teen than the usual ManIFeelLikeAWoman protagonist of a GenderBender webcomic.
* [[http://mylifeinblue.comicgenesis.com/d/20020302.html Marius]] from ''Webcomic/MyLifeInBlue''.
* While Dr Pegasus in ''Webcomic/UmlautHouse'' is a fairly typical GenderBender in the current stories, there have been a few hints that she had to deal with the problems typical of a RealLife transsexual before that.
* [[spoiler:Emerald, formerly Richard]] in ''5ideways''.
* WordOfGod is that [[spoiler:Chelsie Warner]] of ''Webcomic/{{Concession}}'' identifies as female, but since [[spoiler:she's ten years old and, going by her behaviour, suffering from a LOT of sex-related issues]] it's unclear in the comic. [[spoiler:The WhereAreTheyNow epilogue shows her at the age of eighteen, fully transitioned and apparently recovering from her traumatic childhood.]]
* Molly Ricketts in ''[[http://buxompiratewench.comicgenesis.com Rule, Britannia]]'' is transgender, although it's said early on that none of the other characters are sure whether he's [=MtF=] or [=FtM=] (He's later [[http://buxompiratewench.comicgenesis.com/d/20090615.html revealed to be [=FtM=]]].)
* The minor character Aubrey in ''Webcomic/BoyMeetsBoy'' is a pre-op [=FtM=].
* A transsexual character receives a surprisingly sympathetic treatment in ''Webcomic/{{Exiern}}'', a comic which normally plays its [[GenderBender gender benders]] for laughs, when one of a group of gender-bent priests is shown to view it less as a curse and more as a liberation, and her backstory clearly describes someone who entered the priesthood primarily because she was unhappy with her birth gender.
* ''Webcomic/{{Rain}}'' is the title character of a slice-of-life {{dramedy}} webcomic that tells the story of a young transsexual girl who is just starting out her senior year of high school and hoping to fit in and find her way as a woman.
* ''Webcomic/TheDragonQueen'' features the eponymous hero, the city's "first and only transvestite super-hero" who was born Bradley Bartlett but currently dresses female, identifies as Brandywine Bartlett, and has the people around hir use female pronouns.
* In ''Webcomic/TalesOfAGayAsian'', there is a [=MtF=] transsexual sengchou who has stubble and gets further surgery to look like Lady Gaga.
* In ''Webcomic/TheDragonDoctors'', there are plenty of {{Gender Bender}}s, but one actual ([=FtM=]) transsexual does show up in Mori's backstory chapter. In a setting where magic can easily change your gender, this might not seem to be a big issue, but Lem came from a country where magic was strongly discouraged. Worse, Lem was self-medicating with cheap, temporary GenderBender potions that had a toxic after-effect, and he nearly died from it.
* Z from the SliceOfLife JournalComic ''[[http://healthymultiplicity.com/Zyfron/Gemini/ Gemini]]''. An interesting case, as [[SplitPersonality her body is not just her own]]; she shares it with a cis man.
* Casually mentioned in ''Webcomic/DominicDeegan''; the "alterist" (magical plastic surgeon/fertility doctor) Dominic and Luna go to see gives herself as an example of the non-MadScientist applications of alterist magic when Dominic gets freaked out. She looks entirely like an average biological woman (even allowing for the OnlySixFaces artstyle), her status doesn't matter to the story, and the situation isn't played for either laughs or angst.
* The protagonist of ''[[http://whatsnormalanyway.net/ What's Normal Anyway?]]'' is a [=FtM=], and the webcomic mainly revolves around gags related to him.
* The now apparently defunct ''[[http://www.transe-generation.com/default.php Trane-generation]]'' comic was a bunch of gag comics revolving around transgender issues, mainly [=FtM=] ones.
* One of the leading characters in ''[[http://mrnormal.com/ Mr. Normal]]'' is a closeted [=MtF=] trying to not be [=MtF=].
* In ''Webcomic/{{Greg}}'', Greg is hit on by the same transsexual in multiple strips despite his unwillingness to engage. An example [[http://gregcomic.com/2011/11/23/storyline-the-facebook-part-2/ here]].
* ''Webcomic/KarabearComicsUnlimited'' debuted Eiderdown, an MTF superhero, in issue 3.
* Acchan from the [[{{Hentai}} cub]] comic, ''The Neon Children''.
* Several characters in ''{{Webcomic/Unity}}'' and its spin-off stories:
** Juni Melrose, main character in ''Unity'', identifies as neutrois (although their neural clone Zero seems to identify as more feminine, or uses feminine pronouns at least, and also [[spoiler:refers to Juni retroactively as female]]). Juni also seems to get into relationships with other genderqueer characters, such as [[spoiler:Sam Roarke]]. Later, Tanya Harris implies a potential neutrois identification.
** [[spoiler:Alda Henning]] in the Breeder sub-story
** In Blackout, Min is implied to be female-identified but has a male's spurs
* ''Webcomic/ThePrincess'' revolves around a young trans girl named Sarah. Compared to the others it has a considerably lighter tone, being [[WhatDoYouMeanItsNotForKids almost]] like a children's comic.
* Early on in ''Webcomic/8BitTheater'', Red Mage was shown to have various gender identity issues. Later subverted [[spoiler: when it was revealed that he wasn't transgender at all, but that Thief had simply been playing headgames with him to make him think he was, for no apparent reason other than Thief's amusement at the emotional distress this caused him.]]
* ''Webcomic/GhastlysGhastlyComic'' featured Freddy, a woman with a penis and a male name whom the author referred to as "s/he": "I feel s/he transcends all normal concepts of gender. S/he's not gender dysphoric, s/he's gender euphoric."
* Senna in ''Webcomic/MenageA3'' is or appears to be a Brazilian transsexual with a female figure so attractive that she has a job as an international lingerie model, but also with a fully functional penis, along with a highly active sex drive. The comic's cast page flags her as bisexual, but her main interest seems to be seducing attractive men; she's engaged in an extended game of CorruptTheCutie with the naive Gary. Exact details of her condition are unclear; when asked, the writers admitted that [[http://www.pixietrixcomix.com/forum/viewtopic.php?f=4&t=15&hilit=senna&start=1725#p420931 they're keeping their options open]] regarding her history, status and future plans for treatment, but for now, [[http://www.pixietrixcomix.com/forum/viewtopic.php?f=4&t=15&p=399787#p399787 she likes being the way she is]]. She mostly seems to be a joke about one or two real-world transsexual fashion models who've come out of Brazil, while also serving as a source of jokes about Gary's naivety.
* Bedivere in the modern and space arcs of ''Webcomic/ArthurKingOfTimeAndSpace'' following two successive {{Retcon}}s to the original female version. (The first used a series of NoFourthWall strips to establish he was now male but still in a relationship with Kay so the strip had a main gay couple; the second was that the earlier strips where he was physically female were still in continuity.)
* Ultra-Car from ''{{Shortpacked}}'' is an odd example. As the name suggests, Ultra-Car starts as a super-powered robot car whom everyone addresses as male. However, eventually "he" wants to be a girl instead, and has Joe and Rachel build a FemBot body to transfer into. Given these circumstances, she actually refers to herself as a "transchassis woman."
* Jocelyne Brown in ''Webcomic/DumbingOfAge'', Joyce's older brother. At the time of the comic she seems to only use her preferred name in her writing and is not out to her parents.
** Carla is a transgender woman, according to WordOfGod. She's the human counterpart of Ultra-Car from ''{{Webcomic/Shortpacked}},'' above.
* Pheia Tessier is ''Webcomic/{{Holystone}}'' is the setting's equivalent of MtF. The spoken language [[WordOfGod has been stated]] to have gendered dialects, so her gender identity is treated as a non-issue by the rest of the cast.
* ''Calogrenant'' by Gillian Cameron centers on an MTF Knight of the Round Table.
* ''Validation'' by Christian Beranek is a slice of life comic about a transgender girl named Ally.
* Tedd from ''Webcomic/ElGoonishShive'' is genderfluid. He didn't find this out [[http://www.egscomics.com/index.php?id=1896 until Grace told him that being genderfluid was a thing.]]
-->'''Grace:''' You're just...I think it's genderfluid? I'm ''pretty'' sure that applies to you...
-->'''Tedd:''' I'm--that's a thing? There's a name for it?
** Apparently, Grace learned about transsexuality from a [[http://www.egscomics.com/index.php?id=1906 FTM comic store patron]].
* [[http://gqutiecomics.com/ Gqutie]] has protagonist Ronnie, who is genderqueer, and their transgender partner, along with other trans characters.
[[/folder]]

[[folder:Web Original]]
* [[spoiler:The title character]] in ''TheSagaOfTuck'' is a teenager who is [[spoiler:physically intersexed, and (possibly) bi-gender]]. A number of minor characters are also transgender, and several more are {{Transvestite}}s.
* [[GenderBender Gender-bending]] is a common element of the ''{{Paradise}}'' setting. Some (not all) gender-bent characters are WishFulfillment [[AuthorAvatar Author Avatars]] for transgender individuals in real life. Perspectives being a mini-series in that universe about how a transwoman would have lived her teenage life if her best friend and not her had suffered Body Dysphoria instead.
* [[GenderBender Gender-bending]] is even more common in ''{{FreeRIDErs}}'' which was created by the same person, in background material it was mentioned that many who tested out the Gender Bender Nanites in the earlier days of RIDE Development had signed up for it to cure their Gender Dysphoria. Paul Reverbek from the story "As A Woman I RIDE" is an Earth Boy who steals a RIDE to finally be free of her GID, it's written in first person perspective and she's played very sympathetically. On Earth where they don't have RIDEs, people can be scanned for Gender Identity Disorder and if they have it they are given nanites to make their bodies match their minds. There are those on Earth who are peeved because it is illegal to change someone with nanites unless they have GID, one gender-curious man without GID actually goes to Zharus just to see what being a woman is like. Finally it is noted that people who use RIDEs of the opposite sex that they are have their brains modified by the nanites as well as their bodies to ensure they don't develop Gender Dysphoria... though some RIDEs intentionally sabotage themselves or are sabotaged by others in order to give their humans Gender Dysphoria.
* Jade Sinclair (nee Jared Reilley) of the WhateleyUniverse. Toni too, before she got her wish through GenderBending (She was born Tony).
* ''Literature/TalesOfMU'' features Steff, a [=MtF=] [[HalfHumanHybrid half-elf]]. In addition, the culture of the [[OurElvesAreBetter subterranean elves]] features an "ornamental" third gender of [=MtF=]s called "halfkind," who undergo a magical transformation that enhances both breasts and male organs, and who serve mostly as a status symbol for their families. [[spoiler:Steff eventually is given the halfkind potion by a subterranean friend.]]
* ''[[http://shimmerverse.com/ Shimmer: A Superhero Fantasy]]'' has to do with a [=MtF=] {{Superhero Superheroine}} named Glimmer Girl.
* Twinfools of YouTube's "Fighting Dreamers Productions" Cosplay Group was very open about his transition on his own channel, but did not carry it into the groups main content. He remains the driving force behind the group playing a majority of the characters and as the main source of the funny.
* ''Literature/{{Worm}}'' has Circus, a minor supervillain who appears male in civilian identity and female in their costumed one. Even Tattletale isn't entirely sure which gender Circus identifies as, which is presumably their intention.
[[/folder]]

[[folder:Western Animation]]
* In a ''FamilyGuy'' episode, Quagmire's Navy war hero father, Dan, undergoes surgery to become Ida, much to Quagmire's chagrin. Having bungled a GayAesop in a previous episode, the writers tried to make the character sympathetic, but still trotted out the old jokes (including an UnsettlingGenderReveal), and earned the ire of quite a few LGBT people. It didn't help that, when she ''wasn't'' acting stereotypical, Ida was a FlatCharacter at best.
** Seth [=MacFarlane=] then further infuriated the LGBT community by saying that he thought the character was [[http://www.afterelton.com/TV/2010/5/seth-macfarlane-complete-idiot?page=0 "probably the most sympathetic portrayal of a transexual character that has ever been on television."]] Many took this to be proof that [=MacFarlane=] had never ''seen'' a transsexual character on TV.
** The film ''Stewie Griffin: The Untold Story'' also had future-Meg going to college and getting a sex change, becoming a man called Ron.
* Done once on ''TheClevelandShow'' but pulled off with even less tact than the ''FamilyGuy'' example above. The episode doesn't even try to portray Auntie Mama (yes, that's the character's name) in a positive light, portraying her as somone who "manipulates" straight men into loving her and being called a "guy pretending to be a woman." At least with Family Guy there was an attempt at sensitivity and understanding, however clumsy.
* Mr. Garrison, in the least sensitive way possible, during ''WesternAnimation/SouthPark'' Seasons 9-12.
* In ''BobsBurgers'', a positive example of transvestites comes in with "Cabs, Bob? Sheesh!". No hamfisted aesop attatched, just a trio of friendly, funny transvestites (one being a pre-op [=MtF=]) who befriend Bob on his taxi route, and their only negative attribute is the fact that they're implied to be crackwhores. They even help him out in the climax and only one blink-and-you-miss-it UnsettlingGenderReveal joke tucked in.
* Alice in ''WesternAnimation/{{Superjail}}'' is a male-to-female transsexual, though it's played for laughs because she is very clearly masculine (which has lead to some controversy around the character and her implications). Also, clearly pre-operative given the always-noticeable bulge in her skirt, and (censored) depictions of her oversized genitalia. The Warden lusts after her and is initially unaware of this, though it appears he either forgets about seeing her genitalia at the end of season 2 (due to NegativeContinuity) or doesn't mind it.
** Bruce is [[SpearCounterpart the reverse of Alice]] and portrayed as overweight and lisping, with an aggressive temper. His personality is delved into less than hers, though he constantly tries to challenge and one-up her in his appearances.
* ''WesternAnimation/{{Recess}}'' [[GettingCrapPastTheRadar (of all shows!)]] gave us Mikey mentioning his Uncle ''Mary''. Vince is confused to why Mikey's uncle is named Mary, and Gretchen [[DontAsk just tells him not to ask]].
* ''WesternAnimation/AdventureTime'' impressively went there with the "Princess Cookie" episode. Whether Baby Snaps was supposed to be transsexual or just wanted the role of princess is slightly unclear, but the episode, with its unusually serious themes of bullying and suicide, works as an "It Gets Better" message for gender-variant youth.
* Judge Constance Harm of ''TheSimpsons'': "You remind me of me when I was a little boy."
** There are a few characters who are [[http://simpsons.wikia.com/wiki/LGBT_characters implied]] to be trans but it may just be one-off jokes. Brunella Pommelhorst, the elementary PE teacher, was supposed to transition but he still appears as a woman in future episodes.
* Done a couple of times in ''WesternAnimation/{{Futurama}}''. Bender becomes Coilette to keep his Olympic medals in 'Bend-her' and most of the cast have their genders swapped in 'Neutopia'.

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