A birthmark, scar, subcutaneous pigmentation, magical tattoo, or otherwise permanent/semi-permanent mark on a character that somehow ends up being significant to the plot BY A CHANGE IN IT or something unusual that it does; it can't just be static. Disappearance of the mark, the stoppage of its unusual function, or a discovery that the mark was never real is part of this trope. Normal healing of a wound to a scar does not count; a wound that does not heal due to magic or poison may, as long is it does more than just not heal (i.e., bleeds excessively when the inflicter of the wound is near, etc.). Subtrope of DistinguishingMark. With examples, please include the noteworthy change in the mark.

See also PowerTattoo for marks that grant their bearers some abilities, MarkedChange for ones that merely indicate the current status (like SuperMode) and MarkOfTheBeast for EvilMakeover variety.
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!!Examples:

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[[folder: Anime And Manga ]]

* In ''{{Naruto}}'' Sasuke's Curse Seal acts as this immediately after being applied. When his will or chakra weaken enough, it spread across his skin like a rash, causing additional weakness and pain. It is later upgraded to [[MarkOfTheBeast allow him to draw on its power without the side effects]].
* The curse mark on Alan in {{MAR}}. If it goes all the way up his neck, he becomes a zombie slave.
* In ''[[MagicalGirlLyricalNanoha Nanoha Force]]'', the Blue Wings "tattoo" appears somewhere on the body of a person infected with Eclipse and grows larger as the infection progresses.
* [[spoiler: Tomoe]] from ''Manga/KamisamaKiss'' has them appear all over his body thanks to a DealWithTheDevil.
* Oga from ''{{Beelzebub}}'' gets a red mark along his arm that shows his connection with Baby Beel. It is a plot point in early episodes that he must live a peaceful life to remove the mark and go back to his old life. [[StatusQuoIsGod It]] [[RunningGag doesn't]] [[BloodKnight take]].

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[[folder: Film ]]

* Ashitaka's curse mark in ''PrincessMononoke''; the worse it gets, the worse the curse is. Now the TropeCodifier as Franchise/HarryPotter's scar is better known as a DistinguishingMark and a BirthmarkOfDestiny.
* Jack Sparrow's "Black Spot" in the ''PiratesOfTheCaribbean: Dead Man's Chest''. It disappears and reappears as his debt to Jones is settled or still needs to be satisfied.

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[[folder: Literature ]]

* Literature/HarryPotter's scar counts; not only is his scar an indication that he survived the Killing Curse, but [[AcheyScars it twinges]] whenever Voldemort is feeling something particularly strong. The connection to Voldemort becomes stronger as the series continues.
* The titular character's scar in Robin [=McKinley's=] book ''Literature/{{Sunshine}}''. After Sunshine defeats the vampire who gave it to her, it disappears completely.
* In ''[[ForgottenRealms Azure Bonds]]'' the eponymous pseudo-tattoo, among other functions, linked Alias to her bosses via their symbols, and there was a reason behind one empty place in their pattern. These vanished one by one when those masters were removed from the scene permanently, and later a mark of the goddess looking after Alias appeared. So when in the third book an old symbol returned...
* Artek "the Knife" Ar'talen in ''[[ForgottenRealms Escape from Undermountain]]'' was given a magical tattoo after he was "[[RecruitingTheCriminal employed]]" via set-up escape by a noble. It mirrored the sun and moon position in the sky and was set to release a killing spell at the pre-set time -- as an incentive to complete his mission and return for removal before the [[IncrediblyLamePun deadline]].
* In ''TheDresdenFiles,'' a [[OurVampiresAreDifferent Red Court vampire]] doesn't fully turn the moment they're infected, but the first time they kill through feeding; they can even use some vampire powers and drink blood to heal and "recharge" without losing their human selves and becoming evil. The Fellowship of St. Giles, a group of these half-vampires, have tattoos that help control their bloodlust. By default, they're invisible, turn black when the half-vampire's using their enhanced abilities and getting hungry, and bright red when those urges are getting out of their control.
* Vimes' scar in ''Discworld/{{Thud}}'', which he gets from tearing his hand open on a rusty nail and gets eerily inflamed whenever Vimes get angry over some injustice. The scar turns out [[spoiler:to be the entry point where the Summoning Dark came into his body, and after being burned by burning oil in same location the scar turns into a picture of the Summoning Dark.]]

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[[folder: Live Action TV ]]

* In an episode of ''Series/StarTrekEnterprise'', Hoshi Sato is worried that the transporter altered her structural integrity on a molecular level. She cites a mole that moved an inch lower on her face after her transportation as proof. Oh, and she ends up being right.
* In ''Series/PowerRangersLightspeedRescue'', once Ryan the Titanium Ranger [[HeelFaceTurn joins the good guys]], Diabolico inflicts him with a snake tattoo; every time he morphs it'll climb up his back until it reaches his neck and kills him.
* PlayedForComedy in {{NewsRadio}}. An impostor once performed an appendectomy on Max. When the imposter shows up at the station, Max proclaims the scar "knows he's near."
-->'''Max:''' The scar! I can still feel it throbbing!

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[[folder: Truth In Television ]]

* Skin cancer. If one of your {{Beauty Mark}}s turns color, gets bigger, or otherwise starts looking wonky, see an oncologist pronto!
* And, of course, if any sort of wound doesn't heal the way it's supposed to (i.e., scab over with minimal scarring), it's probably infected.

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[[folder: Video Games ]]

* In ''VideoGame/FinalFantasyXIII'', a l'Cie's brand changes in appearance to indicate how much time he/she has to complete his/her [[MissionFromGod Focus]] before [[FateWorseThanDeath becoming a]] [[OurZombiesAreDifferent Cie'th]]. It gets arrows, and then a red eye, when the brand reaches the [[ThirteenIsUnlucky thirteenth]] stage and the eye is fully open the l'Cie becomes a Cie'th. Notably, emotional distress can accelerate the process, so much that the [[AllThereInTheManual datalog]] notes that somebody can become a Cie'th immediately upon branding due to panic/shock/horror about being made l'Cie. Fang's brand is white and blurry, indicating that [[spoiler:she's not on a timer. This happens to the brands on the rest of the cast at the end, and the brands disappear entirely after defeating the final boss]].
* In ''[[VideoGame/SonicStorybookSeries Sonic and the Secret Rings]]'', Sonic is scarred with an arrow of flame. It shrinks with his lifespan; the smaller the flame is, the less time he has to finish [[MacGuffinDeliveryService gathering MacGuffins]]. Right before the final boss, the camera has to zoom in for you to even ''see'' it. [[spoiler: When Shahra [[TakingtheBullet Takes The Bullet]], this thing gets subverted all the way to Jahannam; [[EleventhHourSuperpower Darkspine Sonic]] has his [[Franchise/FantasticFour flame on]], and [[ExtremeMeleeRevenge he is]] '''''[[ExtremeMeleeRevenge not]]''''' [[ExtremeMeleeRevenge scared of using it]]. ]]

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[[folder: Western Animation ]]

* Used in the DanVs episode [[Recap/DanVsS2E28DanVsTheMonsterUnderTheBed "The Monster Under the Bed"]].
* Invoked in the short-lived children's series ''SagwaTheChineseSiameseCat''. In one episode, Sheegwa, Sagwa's younger sister, is discovered to have a star-shaped marking on her fur that is "the mark of the princess", indicating that Sheegwa is actually a princess. Unfortunately, the mark turns out to be dirt.
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