''The Spider and the Fly'' may refer to:

* John Heywood's epic poem "The Spider and the Fly" (1556)
* ''Literature/TheSpiderAndTheFly'', an 1829 poem by Mary Howitt (also included in her book ''Sketches of Natural History'', 1834)
* ''Film/TheSpiderAndTheFly'', a 1949 FilmNoir movie about a love triangle between two criminals and a policeman.
* "The Spider and the Fly", a short animated cartoon in Disney's ''WesternAnimation/SillySymphonies'' series.
* "Music/TheSpiderAndTheFly", a popular song by Music/TheRollingStones.