Uh oh... Alice finds herself captured and strapped to a wall/altar in the center of a big magic symbol. Candles are set in very specific places while an [[OminousLatinChanting Ominous Latin Choir]] hums in the background. It's obvious that she is going to be used in a dark ritual to summon an evil god of sorts, or alternatively, unlock a magical lock to a {{Macguffin}}. There can be several reasons why the evil forces go to the trouble of specifically capturing Alice, instead of just capturing a random innocent victim:

* The BigBad comes back stronger this way.
* They need it to overcome some specific power seal. (Overlaps with 1, but is not identical to it)
* The ritual literally can only be done with Alice's blood/life force.

The actual sacrifice factor can range anywhere from just needing Alice's fresh [[BloodMagic blood]] to needing her [[HumanSacrifice full life force]]. Not that it changes much, since whoever is in lead of the ritual is not going to leave her alive.

Subtrope of HumanSacrifice. The key difference between this trope and HumanSacrifice is that that one would work with any John Doe picked up from the street, this trope specifically needs Alice to make the ritual work, no exceptions.

{{Barrier Maiden}}s tend to be prime targets for this, for obvious reasons.

!! Examples:

[[foldercontrol]]

[[folder: Anime and Manga ]]

* A group from ''{{Naruto}}'' called Akatsuki tries to do this not once, but nine times! They search for the nine Jinchuriki, including protagonists Naruto and Gaara, to extract their inner demons.
* In ''BlueSeed'', it is said that to stop the Aragami, the "Kushinada" (a human literally bred to be a human sacrifice) must be sacrificed. Problem is, this time there are ''two'' twin sisters who qualify as Kushinadas... [[spoiler: and one of them has had a FaceHeelTurn.]]
* In ''Manga/FullmetalAlchemist'', [[BigBad Father]] needs people who not only can open the Gate, but have done it once before and survived: this ends up being [[spoiler:the Elric brothers, Hohenheim, Izumi Curtis, and Roy Mustang]]. Without them, he can't perform his ritual and capture the power of God. They are targeted more because of their skills and experiences than some particular power or bloodline, but finding replacements would be extremely difficult, so it counts.

[[/folder]]

[[folder: Film ]]

* In ''PiratesOfTheCaribbean'', to reverse a curse, the blood of a specific pirate is required - or that of his descendant Will Turner. They only need a small amount, as we learn when they attempt to use Elizabeth. But by the time they got Will, they were angry enough at him that they decided to slit his throat instead.
* The BigBad from the first ''Film/ScoobyDoo'' movie needs a pure soul for his ritual. The only soul meeting the requirements on the whole island is [[spoiler:Scooby's.]]
* ''Manga/{{Bleach}}: Memories of Nobody''. A Shinigami girl named Senna (who is also [[spoiler: the Memory Rosary]]) is captured and tortured by the Dark Ones (exiled Soul Reapers). They try to sacrifice her in order to collapse the Valley of Screams and destroy both the World of the Living and the Soul Society. [[spoiler: They fail, but Senna still dies.]]
* In ''TheWickerMan'', [[spoiler: Howie is slated to be the sacrifice because he's still a virgin, because he's acting as a representative of the Crown, and maybe other reasons]].
* In ''LesbianVampireKillers'', the blood of the last of the [=McLaren's=] is required in the ritual to resurrect Carmilla the Vampire Queen.
* ''Film/TheCabinInTheWoods''. To say any more would be to spoil the whole film.

[[/folder]]

[[folder: Literature ]]

* In ''Literature/HarryPotterAndTheGobletOfFire'', Voldemort casts a ritual requiring the blood of an enemy. As Wormtail points out, nearly the entire wizarding world qualifies, but of course he wanted Harry Potter's, [[spoiler:to circumvent his [[ThePowerOfLove protective ward]].]]
* ''Literature/TheDresdenFiles'' likes this trope.
** In ''Summer Knight'', [[spoiler:Aurora]] needs [[spoiler:Lilly, because she holds the power of the summer knight, and killing her at that time and place will give the power to the Winter Court.]]
** In ''Blood Rites'', [[spoiler:Lord Raith]] needs to kill both [[spoiler:Harry and Thomas]] to break the curse [[spoiler:their mother laid on him, because it's tied to her bloodline]].
** [[spoiler:The Red Court needs to kill Harry's daughter so that the spell will trace her bloodline back and hit both Harry and his grandfather Ebenezar, one of the most powerful wizards in the world.]]

[[/folder]]

[[folder: Live Action Television ]]

* In ''Series/BuffyTheVampireSlayer'' Glory needs Dawn because she's The Key, an interdimensional gateway recently turned into a human being. The fact that activating its power will involve killing her is basically incidental.
* In ''Series/{{Angel}}'', the demon Yeshka has the pretty exacting sacrifice requirements that people have to sacrifice their daughter, she has to be a [[VirginSacrifice virgin]], and it has to be done on the father's fiftieth birthday.
* In ''TheVampireDiaries'', [[spoiler:Klaus needs to sacrifice Elena, the latest "Petrova doppleganger", to break the curse binding him.]] He also needs a vampire and a werewolf, but those are easier to get hold of.
* In the ''Series/DoctorWho'' episode The Girl In The Fireplace, the clockwork androids pursue Reinette because [[spoiler:her body is needed to repair their ship]].

[[/folder]]

[[folder: Video games ]]

* Almost happens to the Avatar in the beginning of ''UltimaVI''.
* Happens in several ''TheLegendOfZelda'' titles.
** In ''ZeldaIITheAdventureOfLink'', [[BigBad Ganon's]] followers are gunning for Link because they need to sprinkle his blood on Ganon's ashes in order to resurrect him.
** In ''ALinkToThePast'', Aghanim/[[spoiler:Ganon]] uses this on the descendants of the seven Sages to release the seal to the Dark World.
** In ''VideoGame/TheLegendOfZeldaOracleGames'', sacrificing Zelda is needed to [[spoiler:revive Ganon]]. When foiled, the perpetrators sacrificed themselves instead, and [[spoiler:Ganon [[CameBackWrong comes back as a mindless beast]]]].
** In ''SkywardSword'', Ghirahim must sacrifice Zelda's soul to release the seal on the demon king [[spoiler:because she is the reincarnation of the goddess who imprisoned him.]]
* In ''{{Persona 3}}'', [[spoiler:Shuji Ikutsuki]] tries to sacrifice the heroes to bring about [[TheEndOfTheWorldAsWeKnowIt The Fall]], but it doesn't work.
* [[spoiler:Colette Brunel]] in ''VideoGame/{{Tales of Symphonia}}'' was to be sacrificed by the {{Big Bad}} [[spoiler:Mithos to resurrect his sister in her body.]] Though it is stated that several other people were used for the ritual before, it has never worked before, most likely due to the body not matching or whatever.
* In ''TheKingOfFighters'', [[spoiler: the original ritual to awaken {{Orochi}} 1800 years ago included plans for the sacrifice of eight {{Barrier Maiden}}s, known as the Kushinadas. Seven of these girls were sacrificed (and in the ''manhua'' they willingly offered themselves as this, having being told that they'd stay young and pretty eternally in exchange), but the last one was rescued by the Kusanagi, Yasakani and Yata leaders, who then went on fighting and sealing Orochi away.]] In the present, [[spoiler: the New Face Team (Yashiro, Shermie and Chris) kidnap the currently last descendant of this surviving Kushinada, a GirlNextDoor from Osaka named Yuki, for the same thing... and [[VillainBall commit the HUGE mistake]] of gloating about their evil plans to Kyo Kusanagi, Chizuru Kagura and Iori Yagami, the descendants of those who fought and sealed Orochi; since Yuki just ''happens'' to be Kyo's girlfriend, [[BerserkButton they piss him off BADLY]]. Obviously, Yuki is saved from them and Orochi is re-sealed.]]
* It's revealed partway through ''VideoGame/RadiantHistoria'' that [[spoiler:the ritual to hold off the end of the world requires someone who's died and been brought back to [[HeroicSacrifice willingly give up their soul]] to power it. There are two potential candidates. Too bad one of them is more inclined to [[PutThemAllOutOfMyMisery let the world end]].]]

[[/folder]]

[[folder: Webcomics ]]

* In ''Webcomic/GunnerkriggCourt'', the first generation of the Court hits upon a self-defense scheme that involves killing a particular person, and immediately afterwards splitting the soul of their grieving lover, so the negative parts of their soul become an angry superpowered spirit, trapped at the place they died. The man who came up with this scheme insisted that the chosen targets were the only ones who would work as a sacrifice, but it's implied that he also selected these two because [[spoiler:one of them was the target of his unrequited affection]].
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