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Also known as [[http://www.oafe.net/blog/2007/01/the-supervillain-shuffle/ The Supervillain Shuffle]]. The occurrence wherein a villain, originally introduced as an enemy for a specific hero, subtly through time or ContinuityCreep, deliberately or unintentionally, becomes more identified with another hero.

While any SharedUniverse may depict a hero fighting another's antagonist, usually they remain identified with the original. For instance, Franchise/{{Superman}} may occasionally fight SelfDemonstrating/TheJoker, but no one would claim the latter is anything but a Franchise/{{Batman}} villain. This trope refers specifically to characters that have reached the narrative point where the villain is now more identified in the popular consciousness as being an adversary to a character he did not originally fight.

Often occurs when an obscure character is used in a recent popular work or adaptation. In many cases, it also happens when the villain is better suited to another hero either thematically or with regard to powers, especially if the themes or powers of the hero have changed in the interim. Can also be the result of a writer creating a villain while writing for one character, then moving on to another project and taking all of their toys with them.

----
!Examples:

[[foldercontrol]]

[[folder:Anime and Manga]]
* While this can't really happen in Japanese comics much due to most manga being stand-alone stories, it has turned up a few times in the works of J-hero king ShotaroIshinomori. The evil Black Ghost organization from ''Manga/{{Cyborg 009}}'' has also shown up in a few manga side stories for ''Franchise/KamenRider'' and ''Manga/SkullMan''.
[[/folder]]

[[folder:Comic Books]]
* Wilson Fisk, TheKingpin, was introduced as a Franchise/SpiderMan villain, and though Spidey still fights him on occasion, you'd be hard-pressed to say that the character is not best known for being a nemesis of Comicbook/{{Daredevil}}, taking the place of the Owl (who is a lot harder to take seriously) among his enemies.
** Referenced (but not used directly) in ''WesternAnimation/{{Spider-Man The Animated Series}}''; Fisk is the BigBad for much of the show, but in the episode where Daredevil does appear, it's made very clear that for him, ItsPersonal, while for Spidey, it's more of your standard hero/villain thing.
*** [[WordOfGod Greg Weisman]] says they wanted Kingpin to be one of the {{Big Bad}}s on ''WesternAnimation/TheSpectacularSpiderMan,'' but couldn't specifically because he was technically classified as a ''Daredevil'' character now. (Sony only had the rights to ''Spider-Man'' characters.)
** Other Spidey villains have been known to torment Daredevil from time to time, and vice-versa; the guys practically live next door to each other, so there's a ton of overlap. Inverted with Mysterio who seems to have not so much transferred to Daredevil's gallery as branched out, becoming an enemy of both of them.
** By comparison, the various Green Goblins were notable for being solely Spider-Man villains, never antagonizing other New York-based heroes as DoctorOctopus or Electro would. Since ''SecretInvasion'', however, NormanOsborn has been transformed into an over-riding BigBad of the Franchise/MarvelUniverse. After trying to take the Avengers again with another team of Comicbook/DarkAvengers and a H.A.M.M.E.R. made up of HYDRA and A.I.M. personnel, he has gone back to being a Spidey villain. [[spoiler:Firmly reestablished at the GrandFinale of ''Comicbook/SuperiorSpiderMan'']].
** Since his resurrection Kraven the Hunter and his daughter Ana has been seen fighting other superheroes on a daily basis, mostly related to Spider-Man like ComicBook/{{Venom}} or [[Comicbook/{{Spider-Woman}} Spider-Girl]], but Comicbook/BlackPanther and Comicbook/IncredibleHulk are also fair game. It helps Kraven seems to now live in the Savage Land, a place commonly visited by various superheroes.
*** In Arana's time as Spider-Girl most of her antagonists were minor Spider-Man villains, like above mentioned Ana Kravinoff, Screwball or Hobgoblin.
* Fin Fang Foom was originally a general Franchise/MarvelUniverse monster. He has become an Comicbook/IronMan villain to the point that he has appeared in both WesternAnimation/{{Iron|Man}} [[WesternAnimation/IronManArmoredAdventures Man]] cartoon series, was featured in the animated movie, and was considered as a foe for the live-action Film/IronMan movie... presumably without [[MonsterModesty the purple shorts]]. He still shows up in a FreezeFrameBonus, on a billboard.
* Solomon Grundy was originally specifically an enemy of the ([[TheGoldenAgeOfComicBooks Golden Age]]) Franchise/GreenLantern. However, due to his appearances in various [[WesternAnimation/{{Superfriends}} animated]] [[WesternAnimation/JusticeLeague series]], and the fact that several comic book creators still identify him as a Golden Age villain, Grundy is now more of a standard DC Universe villain. Similarly another Golden Age Green Lantern villain ComicBook/VandalSavage is also now used as a general DC Universe villain, going up against numerous heroes.
* Comicbook/{{Aquaman}} has a habit of appropriating water based villains that originally debuted in other titles, such as The Shark and King Shark, Shark themed villains who started out menacing Green Lantern and ComicBook/{{Superboy}}, respectively.
* The Shade was originally created as a villain for Franchise/TheFlash, but in the modern age, he's perhaps best known for being a TricksterMentor for the Jack Knight incarnation of ''Comicbook/{{Starman}}''.
** An in-universe version is how the Mist originally fought the Wesley Dodds incarnation of the {{Sandman|MysteryTheatre}} before moving to Opal City and fighting Starman. This fact is used as a plot-point in the 1990s series.
* Doctor Destiny was originally created as a villain for the ''Franchise/JusticeLeagueOfAmerica'', and specifically Franchise/GreenLantern. However, he is now almost certainly best known today for being the sap who got his hand on the magical ruby created by the King of Dreams, Morpheus, in ''ComicBook/TheSandman''.
* Jason Woodrue the Floronic Man, created as an adversary of Comicbook/TheAtom, is obscure outside of his appearances in Creator/AlanMoore's run on ''Comicbook/SwampThing'' and Creator/NeilGaiman making him integral to the creation of Poison Ivy in a ''Secret Origins'' story.
* Hank Henshaw, [[Characters/SupermanVillains the Cyborg Superman]] was, unsurprisingly, originally created as a recurring villain in the Franchise/{{Superman}} titles. The character then disappeared for several years. The Cyborg has since re-emerged as a Franchise/GreenLantern villain, with many of his Superman-related appearances excised from continuity, due to his actions in ''Reign of the Supermen'' touching off Hal Jordan's temporary FaceHeelTurn, and his eventually joining the [[Characters/GLSinestroCorps Sinestro Corps]].
** The same thing happened with [[Characters/GLOtherVillains Mongul II.]] His father was a Superman villain, and also the one who helped the Cyborg-Superman destroy Coast City. After being killed for refusing a pact with, and then trying to punch, [[BrokeYourArmPunchingOutCthulhu Neron]], his son appeared a few years later as a foe of Superman. Nowadays, he fights Green Lantern and the Green Lantern Corps.
* Mephisto works well as a deliberate example: He was originally introduced in the ''ComicBook/SilverSurfer'' series, but has spent stints as an adversary of both Comicbook/TheMightyThor and Comicbook/GhostRider. To the modern reader, though, he's best known for his role in ''Comicbook/OneMoreDay''. Mephisto is best understood as a member of the RoguesGallery for the wider Marvel Universe, rather than any one hero, which is fitting as he is basically a stand-in for {{Satan}}. He has tangled with nearly every single major hero and several villains, and is a lot more personal for many.
* Clock King was originally introduced as an adversary of Comicbook/GreenArrow, but is now considered to be a minor member of Franchise/{{Batman}}'s RoguesGallery, due in large part to his appearances in the Franchise/{{DCAU}}. (And [[Series/{{Batman}} the sixties TV series]].)
* Comicbook/LadyShiva was originally the archnemesis of Richard Dragon, but she was later brought over into the Batman mythos, particularly Comicbook/{{Robin|Series}}, [[Comicbook/{{Batgirl 2000}} Batgirl]], and Comicbook/BirdsOfPrey, and has become much more well-known than Richard.
* {{Darkseid}} is a circular example of the trope. He was introduced in Franchise/{{Superman}}'s ''Jimmy Olsen'' title, en route to becoming the specific villain of the Comicbook/NewGods series. With said title's cancellation, he has become associated with Superman's rogues gallery. This likely due to how well he serves as a counterpoint to the Man of Steel: a super-powerful alien who comes to Earth to rule mankind, not serve it, and being one of the few foes of a similar weight class. He's also fairly strongly associated with the ComicBook/{{Legion of Super-Heroes}}, thanks to the classic storyline "The Great Darkness Saga". He's also a popular villain for CrisisCrossover stories that encompass all of Franchise/TheDCU, such as ''Legends'' in 1986, ''Genesis'' in 1997, and ''Comicbook/FinalCrisis'' in 2008.
* Rhino was introduced as a Franchise/SpiderMan foe but has spent most of his career battling the Hulk. At the very least, it's shared custody.
* Professor Arnold Hugo (a man who gave himself super-intelligence at the cost of an oversized cranium), debuted as a Batman opponent, but languished in obscurity until he was reused as a MartianManhunter foe, reappearing several times.
* Comicbook/{{Thanos}} first appeared as an enemy of Iron Man, though he is now more commonly linked with the ''ComicBook/SilverSurfer'' mythos, (Marvel Comics') [[ComicBook/CaptainMarVell Captain Marvel]], and then with Comicbook/AdamWarlock. Like Mephisto, he's now pretty much a general enemy of the entire lineup of "Cosmic Marvel" characters, if not the whole Marvelverse.
* Seems to be all over Comicbook/{{Wolverine}}'s mythos.
** Wolvie himself started out as a foe of the Hulk.
** Sabretooth was a foe of [[ComicBook/ImmortalIronFist Iron Fist]]. Incidentally, Sabretooth was originally intended to be Wolverine's father by creator John Byrne (he was based on Byrne's rejected design for Wolverine sans mask), but ended up getting dumped onto the Iron Fist title when Claremont and Cockrum weren't interested. Years later, Claremont decided to bring `Tooth into the Wolverine fold.
** Also notable is that Lady Deathstrike first appeared fighting Daredevil.
** So did the first Silver Samurai.
** A lesser example would be Omega Red who started off as an X-Men foe before focusing squarely on Wolverine. In the UltimateMarvel universe, Omega Red is primarily a foe of [[Comicbook/UltimateSpiderMan Peter Parker]] and his successor, [[AffirmativeActionLegacy Miles Morales]].
* Franchise/{{Superman}}'s first supervillain was the Ultra-Humanite, but he was {{retcon}}ned to be a JusticeSocietyOfAmerica villain after [[TheGoldenAgeOfComicBooks Golden Age]] Superman was removed from continuity. He also served as the main villain of PowerGirl's solo series.
* Sandman was introduced in the pages of ''The Amazing Spider-Man'' and was a regular baddie for some time before switching over to menace the ComicBook/FantasticFour for some time with the Frightful Four then go solo again fighting Spidey.
* The [[PsychoForHire contract killer]] Boomerang, who uses [[ExactlyWhatItSaysOnTheTin deadly gimmick boomerangs as his weapons]], originally started out fighting [[Comicbook/IncredibleHulk the Hulk]], before he moved on to become a semi-regular Franchise/SpiderMan villain after writers realized that trick boomerangs versus the most powerful creature on earth was a bit of a mismatch.
* Mister Hyde, a villain based on ''Literature/TheStrangeCaseOfDrJekyllAndMrHyde'', started out as a [[Comicbook/TheMightyThor Thor]] villain but would later move on to become a Comicbook/{{Daredevil}} regular, although he also took the time to mess with Franchise/SpiderMan, Comicbook/CaptainAmerica, Comicbook/GhostRider, and [[Comicbook/IncredibleHulk the Hulk]], finally settling in to become a regular foe of Cap, DD and the Big Green Machine. Cobra, Mister Hyde's sometime partner, also started out as a [[Comicbook/TheMightyThor Thor]] villain. Wisely, he has decided against challenging the god of thunder and became a foe of Comicbook/{{Daredevil}} and Comicbook/CaptainAmerica. An early storyline had Comicbook/{{Loki}} enhancing both their powers so they stood a chance against Thor.
* In the very early days of the Franchise/MarvelUniverse, the original Human Torch had his own rogues gallery as a solo hero. Two of his mainstays, the Wizard and the Trapster, would later become enemies of the ComicBook/FantasticFour, with the Wizard becoming an EvilCounterpart to Reed Richards and even forming his own EvilCounterpart team in the Frightful Four, of which the Trapster was a charter member. The Trapster and the Beetle, another long-standing enemy of the Torch, would also become recurring enemies of Franchise/SpiderMan. The Eel also originally debuted as a foe of the Human Torch before becoming a semi-regular ''Comicbook/{{Daredevil}}'' villain.
** It's so pronounced that in both the ''Ultimate Spider-Man'' [[Comicbook/UltimateSpiderMan comic]] and [[WesternAnimation/UltimateSpiderMan TV show]], the Beetle is more or less treated as a straight-up Spidey villain.
* Many of the enemies the various members of Comicbook/TheAvengers had faced as solo heroes would later become enemies of the team as a whole, with characters like [[MadScientist Egghead]], an enemy of Comicbook/{{Ant-Man}}, AKA Henry Pym, [[ThoseWackyNazis Baron Zemo]] (an enemy of Comicbook/CaptainAmerica), [[ManipulativeBastard the Norse trickster god Loki]], an enemy of Comicbook/TheMightyThor, and the Mandarin, the ArchEnemy of Comicbook/IronMan all becoming some of the Avengers' worst enemies. This would also get inverted. The first incarnation of the Masters of Evil featured the Black Knight as a foil for Wasp and Giant Man and Radioactive Man as the foil for Thor. Soon after, both became regular enemies of Comicbook/IronMan.
* The Silver Samurai and Arcade debuted in the pages of ''Comicbook/{{Daredevil}}'' and ''Spider-Man'', respectively, but these days they're better known as Comicbook/{{X-Men}} villains. Arcade then moved on to be the villain for young Marvel superheroes, since the X-Men got more savvy and DarkerAndEdgier. He trapped the Comicbook/AvengersAcademy kids and the [[TheModernAgeOfComicBooks Modern Age]] Young Allies in Murderworld, and is the main villain in ''Comicbook/AvengersArena'', a ''Literature/BattleRoyale'' type title starring many Marvel teens.
* Mystique first appeared in ''Comicbook/MsMarvel'' and was originally slated to be her ArchEnemy. She's pretty much entirely an X-Villain nowadays, and her history with Ms. Marvel (such as [[StuffedInTheFridge killing her boyfriend]]) has been all but forgotten. She did return to torment Comicbook/MsMarvel in Carol's later series.
** It's basically because of her that Rogue was a FlyingBrick in the late 80's through the 90's, though. And because of this, Carol hates Anna's guts.
* ComicBook/{{Deathstroke}} the Terminator started out as a ComicBook/TeenTitans rogue, turned towards antiheroism, and then became (after ''ComicBook/IdentityCrisis'') [[HeelFaceRevolvingDoor a sort of generic DCUniverse villain]], being as much of a dick to as many superheroes as he could manage. He seems to have a hobby of [[PickOnSomeoneYourOwnSize harassing young heroes.]] He's never let go of his grudge against the Titans since he never completed his contract against them (a bit of a blow to his merc cred). He even went so far as to harass Damian Wayne, his ArchEnemy Comicbook/{{Nightwing}}'s (who was, for a while, Batman) protege.
* [[Characters/SupermanVillains Superboy-Prime]] first appeared as a hero in the Franchise/{{Superman}} team-up series ''ComicBook/DCComicsPresents''. His FaceHeelTurn occurred in the CrisisCrossover '' Comicbook/InfiniteCrisis'', which put him up against many heroes of Franchise/TheDCU. He later faced Franchise/GreenLantern as an ally of the Sinestro Corps. After that, he fought the ComicBook/{{Legion of Super-Heroes}} during ''Comicbook/FinalCrisis''. He got to be the VillainProtagonist of his own EvilVersusEvil story during '' Comicbook/BlackestNight''.
* Apocalypse first appeared in ''Comicbook/{{X-Factor}}'' as the leader of the Alliance of Evil (a role, again, originally intended for the Owl) eventually becoming their BigBad, getting killed, and, upon resurrection, graduating to become one of the ComicBook/{{X-Men}}'s most powerful foes and being {{retcon}}ned as Comicbook/{{Cable}}'s archenemy. The former might not be quite enough to qualify as this trope since the incarnation of X-Factor that had Apocalypse as the BigBad consisted of the original five X-Men, making the whole thing X-Men in all but name to begin with. Cable, on the other hand, while very much an X-Men related character, has his own distinct rogues gallery that usually only overlaps with the X-Men during crossover events.
* Deathbird started as a MsMarvel villain before becoming a recurring foe of the ComicBook/{{X-Men}} in general and Professor X's girlfriend Lilandra (her sister, as it turns out) in particular. Like Mystique above, this is a result of Creator/ChrisClaremont creating a villain for one book, then moving her to another when the first was canceled.
* The demon Blackheart debuted in Daredevil, though now spends most of his time messing with Comicbook/GhostRider, even appearing as the villain in [[Film/GhostRider the movie adaptation]]. He also shows up in the ComicBook/{{X-Men}} from time to time (amongst others), even at one point serving as the Black King of the Hellfire Club.
* Minor-league Comicbook/IronMan villains [[AnIcePerson Blizzard]] and [[PlayingWithFire Firebrand]] started out fighting Shellhead, but eventually transitioned to fighting street-level heroes like Franchise/SpiderMan after Tony Stark's equipment began to completely outclass theirs.
* Moses Magnum started out fighting Spider-Man and Comicbook/ThePunisher, but seems to have eventually settled on antagonizing Comicbook/BlackPanther. Thematically, Magnum and T'Challa are a perfect fit.
* Bolivar Trask is most associated with the ComicBook/{{X-Men}} in mainstream Marvel continuity, but in the UltimateUniverse he became integrated into Comicbook/UltimateSpiderMan's mythos, eventually becoming the BigBad of [[VideoGame/UltimateSpiderMan the video game adaptation]].
* The Absorbing Man, who was able to [[PowerCopying mimic and absorb the physical properties of anything he touched]], started out as a recurring enemy of Comicbook/TheMightyThor and remains a charter member of Thor's RoguesGallery. However, he's also tangled with the Comicbook/IncredibleHulk enough times that, as with the Rhino (see above), it's arguably shared custody.
* SelfDemonstrating/DoctorDoom was created to be the main nemesis of the ComicBook/FantasticFour. While he still maintains that role to the present day, he has since become one of the overall Big Bads of the Marvel universe and has fought pretty much every single Marvel hero. Most prevalent are his tussles with Comicbook/BlackPanther. Even other villains are not safe from Doom. He will gladly co-op with the heroes if he feels it serves his interests. [[ChronicBackstabbingDisorder Of course, once the interests are served...]]
* In ''Comicbook/ArchieComicsSonicTheHedgehog'' series, the Dark Legion - a group of villainous Echidnas - was originally created to serve as enemies of Knuckles, acting as the central antagonists of his spin-off. However, after the "Enerjak Reborn" arc in the main series (several years after the ''Knuckles'' spin-off was cancelled), the Legion allied with Sonic's ArchEnemy Dr. Eggman and began serving as his personal army. Therefore, they can be seen as much Sonic's enemies as Knuckles' these days.
* Comicbook/{{MODOK}} was originally created as a foe for Captain America. However, in his role as leader of AIM, he's been increasingly an antagonist of Comicbook/IronMan. And then Hulk, as he created Comicbook/RedHulk.
* The Electrocutioner began as a one-shot Franchise/{{Batman}} villain before appearing in ''The Vigilante'' where he became the closest thing Vig had to an archenemy. Since the Vigilante's death, he has returned as a sporadic Batman foe.
* ''ComicBook/{{Annihilation}}'' has the ComicBook/FantasticFour's long-time foe Annihilus launching a devastating attack on the universe, uniting cosmic heroes like Comicbook/{{Nova}} and the ComicBook/SilverSurfer against him. Even through Annihilus returned a few years later to fight the first family again, he is now generally considered a threat to the entire universe.
** ''Annihilation Conquest'' does a similar thing - Avengers villain Ultron takes control over the Phalanx, a race mostly known for their fights with the X-Men, as well as few lesser-known villains like the Avengers' enemy Ultra-Adaptoid or the Fantastic Four's foe Blastaar, and then goes against cosmic heroes. Ultron later returned to fighting the Avengers, though.
** In a similar vein, ''WarOfKings'' is driven by conflict between the Kree Empire, ruled by Comicbook/TheInhumans, and the Shi'Ar Empire, ruled by X-Men foe Vulcan. Time will show which group Vulcan will stick to antagonizing.
** ''TheThanosImperative'' and a few other appearances helped classic Comicbook/DoctorStrange enemy Shuma-Gorath get upgraded to universal threat, like Mephisto or Thanos. Arguably Shuma-Gorath lost his association with Doctor Strange when he [[UnexpectedCharacter unexpectedly appeared in]] ''VideoGame/MarvelSuperHeroes'', [[AdaptedOut where Strange was absent.]]
* Demogorge the God Eater and Amatsu Mikaboshi all debuted as antagonists of Comicbook/TheMightyThor. To modern readers they are probably known as enemies and [[EnemyMine occasional allies]] of Comicbook/TheIncredibleHercules.
* The Queen of Fables started out attacking the entire JLA, but now she is an enemy to both Franchise/WonderWoman and Franchise/{{Superman}}.
* Comicbook/ThePunisher has few reoccurring villains due to his deadly nature but one of his few villains, Jigsaw, started off as a Spider-Man villain, although his introductory story did involve Punisher as well. Punisher himself was a Spider-Man villain, however he was more of an antagonistic AntiHero and now has his own titles where he scuffles with every street level hero when he's not massacring normal criminals.
* [[DemonLordsAndArchdevils Blaze and Satanus]] began as demonic ''Franchise/{{Superman}}'' villains, but were later revealed to be the half-human offspring of the wizard Comicbook/{{Shazam}}. They've since become joint enemies of both the Superman and Marvel Families.
* Speaking of ''Comicbook/{{Shazam}}'' foes, Dr. Sivana used to be the [[InSeriesNickname Big Red Cheese's]] ArchEnemy, but eventually disappeared from Marvel stories to become the DC Universe's standard MadScientist. He returns as a Shazam foe in the Comicbook/{{New 52}}'s ''Shazam'' series.
* The Marvel Comic story arc "Acts of Vengeance" best describes this trope. It involves the very idea of [[OpponentSwitch a wide array of super-villains facing heroes they had never met (or at least were villains that weren't part of the heroes' regular gallery)]]. Such examples were Comicbook/AlphaFlight fighting Scorpion, Spider-Man (who was granted cosmic powers at the time) fought Goliath, The Brothers Grimm, Titania, SelfDemonstrating/{{Magneto}}, Graviton, Trapster, Dragon-Man, and the Tri-Sentinel. Daredevil fought Ultron, Thor fought Juggernaut, Mandarin appears in the X-Men issues, and Rusty and Skids of the NewMutants battle the Vulture. Even Magneto went against the RedSkull for very obvious reasons.
* Marv Wolfman originally created Black Cat as an enemy for Comicbook/{{Spider-Woman}}; however, Wolfman was transferred to ''Spider-Man'' before he could introduce her, and he brought her with him.
* Silver Banshee has historically been a Superman foe but in recent years she's been more associated with Comicbook/{{Supergirl}}. In the Comicbook/{{New 52}} she is even a (currently non-villainous) supporting cast member in Supergirl's comic.
* Similar to Shuma-Gorath, Nightmare started as a Doctor Strange foe, but has since then fought with pretty much everybody.
* Done intentionally in ''[[Comicbook/{{Fables}} The Great Fables Crossover]]'' in which Snow White and Bigby Wolf deal with Literals, antagonists of ''Fables'' spin-off series ''Jack of Fables'', while Jack, who clashed with them all the time until this point, doesn't move a finger to help.
* Thanks to sharing continuity, Marvel's [[ComicBook/GIJoeARealAmericanHeroMarvel G.I.Joe]] series had an entire story arc with [[ComicBook/TheTransformers Megatron]] as the antagonist.
* An {{inver|tedTrope}}sion happened to The Pride - they were always antagonists of the ''ComicBook/{{Runaways}}'' and it would be pretty hard to introduce them fighting any other superheroes while their entire point was they kept their operations under their radar. That was the case until the creation of [[Comicbook/NewAvengers Avengers Illuminatti]] who were also working in secret from the entire Marvel superheroic community. So of course there exist comics that revealed the two groups clashed back in the days when the Runaways were still only kids.
* [[Characters/GLOtherVillains Hector Hammond]], a longtime enemy of Franchise/GreenLantern, is recast as a Franchise/{{Superman}} villain in the ComicBook/{{New 52}}. As the Green Lantern rarely deals with human, Earthbound threats these days, if Hammond were to see any use at all it would ''have'' to be fighting another hero.
** On that note, the Prankster, who exclusively fought Superman in the past, is now something like Comicbook/{{Nightwing}}'s archenemy. He bears little resemblance to any previous incarnation of the character, however.
** When Nightwing moved to Bludhaven at the start of his solo title, the Batman villain Blockbuster was imported. A kid genius turned DumbMuscle in Batman, Blockbuster had just recently found a way to regain his genius while keeping his super strength and was now a Bludhaven crimelord.
* After Doctor Sun was defeated in ''Comicbook/TheTombOfDracula'' by the joined forces of Dracula and the vampire hunters, he went to antagonize Comicbook/{{Nova}} and Comicbook/FantasticFour.
[[/folder]]

[[folder:Films -- Animated]]
* While Maleficent is still primarily known as the main antagonist of ''Disney/SleepingBeauty'', crossover shows and theme park attractions, as well as ''VideoGame/KingdomHearts'', usually make her something like an arch-Disney villain and her connections to Princess Aurora are barely mentioned.
[[/folder]]

[[folder:Films -- Live-Action]]
* The {{Kaiju}} Baragon was originally the enemy of a giant version of FrankensteinsMonster in ''Film/FrankensteinConquersTheWorld''. However, Baragon eventually became part of Franchise/{{Godzilla}}'s RoguesGallery thanks to video-games, action figures, and the films ''Film/DestroyAllMonsters'' and ''Film/GodzillaMothraKingGhidorahGiantMonstersAllOutAttack''.
* Both Franchise/{{Alien}} and Franchise/{{Predator}} started as antagonists in their own movies. Today, the two races are more known for [[Franchise/AlienVsPredator fighting each other]].
* Thanos is usually associated with [[ComicBook/CaptainMarVell Captain Marvel]] and the ComicBook/SilverSurfer, but appeared as [[spoiler: the mastermind behind the events of ''Film/TheAvengers'']].
* Viper started off as a Comicbook/CaptainAmerica foe and is usually an enemy of Comicbook/NickFury and ComicBook/{{SHIELD}} as well (to the point that she's now known as Madame Hydra). Despite this, she is one of the antagonists in ''Film/TheWolverine''. Understandable since despite her connections to Captain America and S.H.I.E.L.D., she has appeared in several notable Wolverine storylines.
* ''Film/StarTrekIntoDarkness'': [[spoiler: Khan]], in a change up from the original chain of events, ends up with [[spoiler: Spock]] as his primary adversary in this film. He lacks the grudge that defined him [[spoiler: from being marooned by Kirk in the prime-timeline, and ends up spending more time in an EnemyMine with Kirk than he does fighting him, since without that glaring flaw of ItsPersonal with Kirk, he can make wiser decisions around him. Kirk]] still seems to gain his respect as a WorthyOpponent with a similar care for his crew, but this movie might be called [[spoiler: Wrath of Spock once Kirk's {{Almost Dead|Guy}}]].
[[/folder]]

[[folder:Live Action TV]]
* ''Series/{{Batman}}'' had the Comicbook/GreenArrow foe Clock King acting as a member of Batman's rogues gallery. Similarly, minor Superman villain Puzzler was once used instead of Comicbook/TheRiddler for a two part episode, due to a contract dispute with Frank Gorshin.
** The Archer also originated as a minor Superman villain in the comics before appearing on this show as a Batman villain.
* Darla was introduced in ''Series/BuffyTheVampireSlayer'' as a DarkActionGirl Female Vampire Antagonist for Buffy, though was killed off soon after her debut. However, she was revived as a much more potent and ongoing adversary for Series/{{Angel}} in his eponymous spinoff; even in Buffy they had a much more significant connection, as Darla was established as both his vampiric sire and former lover.
* The Slitheen family started out as briefly recurring antagonists (two episodes, one of which was a two-parter) of [[Series/DoctorWho the Ninth Doctor]], then disappeared from the main series and started showing up frequently on ''Series/TheSarahJaneAdventures''.
** The Great Intelligence was initially a Second Doctor villain, but now has more ties with the Eleventh.
* The Cardassians began as villains of the week on ''Series/StarTrekTheNextGeneration'' but ended-up with much greater plot significance on ''[[Series/StarTrekDeepSpaceNine Deep Space Nine]].''
** To a somewhat lesser extent, the same thing could also be said of the Romulans being more associated with ''[[Series/StarTrekTheNextGeneration The Next Generation]]'' than with ''TOS''.
** The Borg are partially this trope and partially an aversion. They had only four ''TNG'' episodes (of which two were two-parters) plus ''First Contact''. Compare this to their twenty (of which four were two-parters) appearances on ''Voyager'', plus a Borg character joining Voyager's main cast for the last four seasons. (They also appeared in one episode of ''Enterprise'', and formed a major part of Sisko's backstory on ''Deep Space Nine''.) Despite this, in popular consciousness, the Borg are still considered Picard's nemesis.
* The Comicbook/GreenArrow adaptation ''Series/{{Arrow}}'' has Comicbook/{{Deadshot}} and Comicbook/{{Deathstroke}} as recurring foes. Deadshot is a Batman villain usually associated with the Comicbook/SuicideSquad and SecretSix, while Deathstroke is traditionally an enemy of the Comicbook/TeenTitans. Along those same lines, ''Series/{{Smallville}}'' had Deathstroke show up as a recurring foe despite having little if any connection to the Franchise/{{Superman}} mythos. Although ''Smallville'' is [[AlreadyMetEveryone pretty infamous about it]] In an inverse of the ''Batman'' example from above, ''Arrow'' also uses Firefly and Dollmaker (both of whom are Batman villains).
** Arrow's second season continues the trend, using (among others) Solomon Grundy, Nyssa al Ghul, and Brother Blood.
* ''Series/OnceUponATime'' puts either Rumplestiltskin or the queen from Snow White in ''everything''. So far Rumple has been Cinderella's fairy godmother, Beauty's Beast, and Captain Hook's crocodile, while Regina has been the Little Mermaid's Sea Witch and the wicked stepmother who abandoned Hansel and Gretel (though not actually their stepmother, she was still responsible for the events.) Then there's the spin-off, ''Series/OnceUponATimeInWonderland'', in which Alice's main antagonist is [[Disney/{{Aladdin}} Jafar.]]
[[/folder]]

[[folder:Video Games]]
* While the ''VideoGame/SuperRobotWars'' series does, of necessity, involve various HumongousMecha fighting enemies from different shows, it can sometimes veer into this territory with especially strong enmities developing between characters of different series, especially in regards to OriginalGeneration characters. The best example would probably be from ''VideoGame/SuperRobotWarsOriginalGeneration 2'', where Axel Almer of '' VideoGame/SuperRobotWarsAdvance'' fame becomes the arch nemesis of the [[VideoGame/SuperRobotWarsCompact2 Impact series]]' Kyosuke Nanbu.
* Seifer of ''VideoGame/FinalFantasyVIII'', known for being Squall's RivalTurnedEvil plays TheRival to Roxas, a member of MassiveMultiplayerCrossover series ''Franchise/KingdomHearts''' OriginalGeneration, and has nothing to do with Squall.
* In ''VideoGame/SuperSmashBros'', Wario, Bowser and Ganondorf become a general BigBadEnsemble of the Nintendo universe, with only the former interacting at all with a character he was initially associated with.
** Master Hand of the game's OriginalGeneration became a Kirby mini-boss and then teamed up with Crazy Hand to be a boss proper in ''VideoGame/KirbyAndTheAmazingMirror''. In this case, it's because both games were made by Hal Laboratory.
* Chaos from ''VideoGame/FinalFantasyI'' is actually the BigBad of the entire ''Franchise/FinalFantasy'' [[TheMultiverse Multiverse]] as of ''VideoGame/DissidiaFinalFantasy''.
** Also happened before that as well, since [[spoiler:he is actually Garland's OneWingedAngel incarnation, and Garland is TheManBehindTheMan in ''VideoGame/FinalFantasyIX'', though it's ambiguous as to whether they're the same character.]]
** Gilgamesh was TheDragon in ''VideoGame/FinalFantasyV'', but is now [[WalkingTheEarth Walking The Multi Verse]] as a BonusBoss.
* In ''X-Men: The Official Game'' (the prequel to ''Film/XMenTheLastStand''), the HYDRA organization is depicted as being the true creators of Master Mold and the Sentinels, the mutant-hunting {{Killer Robot}}s from the X-Men books. In the actual comics, HYDRA is traditionally depicted as a threat to CaptainAmerica and Comicbook/TheAvengers.
[[/folder]]

[[folder:Web Original]]
* The Angry German Kid originally started out as a Website/YouTube Meme, but eventually became one of the main memes at Nico Douga, with the new moniker of Keyboard Crusher.
* In the ''GlobalGuardiansPBEMUniverse'', Doctor XX was originally created to be an ongoing antagonist for the titular Global Guardians team. But then, after the GameMaster for the [[SuperheroSchool Hyperion Academy]] campaign got ahold of her, she tended to never appear in any other campaign so as to "not ruin her amazing portrayal in that campaign".
** In a reverse of the previous example, [[OmnicidalManiac The Blood Red King]] was originally intended to be a semi-demonic villain for the Knights of Malta (a team of superhero priests, monks, and nuns sponsored by the Roman Catholic Church). He ended up fighting the Global Guardians more than any other hero team in the setting.
* {{Lampshade|Hanging}}d on ''WebVideo/AtopTheFourthWall:''
-->'''Cloak #1:''' They think ''that's'' confusing? Why am I suddenly one of your bad guys when you weren't even in the group I was harassing in ''WebVideo/SuburbanKnights?''
* After WebVideo/TheNostalgiaCritic's battle with Creator/MaraWilson, she shows up in WebVideo/TheNostalgiaChick's review of ''Film/{{Matilda}}.'' At first Mara wants to kill her to get to the Critic, but since [[spoiler:he died in ''WebVideo/ToBoldlyFlee'']] the two try to come up with another reason to hate each other, to no avail.
[[/folder]]

[[folder:Western Animation]]
* Most of the villains on ''WesternAnimation/BatmanTheBraveAndTheBold'' qualify, Gentleman Ghost in particular. He was a minor enemy of Comicbook/{{Hawkman}}, but has had three episodes in a Batman-centric show devoted to him before Hawkman was even ''mentioned''. One episode actually had Batman replacing Hawkman in the Ghost's origin story, which more or less explains the difference. The series tried to do this on purpose. Outside of his own (rarely used) rogues' gallery, it's actually fairly rare for Batman to fight an enemy that regularly opposed the team up partner for that episode. (Featured teamup during Gentleman Ghost's origin story? {{Etrigan}}!)
* ''WesternAnimation/JusticeLeague''
** As mentioned in the comics section, Solomon Grundy does not fight against Franchise/GreenLantern ''or'' Franchise/{{Batman}}, but instead against Franchise/{{Superman}} and Hawkgirl.
** ''Unlimited'' portrayed Devil Ray (the CaptainErsatz of Black Manta) as a foe of Franchise/WonderWoman instead of ComicBook/{{Aquaman}}. This was due to rights issues with the failed ''Mercy Reef'' pilot that kept Aquaman himself from appearing in the last season of JLU.
** Gentleman Ghost and Shadow Thief spend most of their time fighting Franchise/GreenLantern instead of Hawkman, although it is due to their LoveTriangle involving Hawkgirl.
* ''WesternAnimation/BatmanTheAnimatedSeries'' used Clock King and Count Vertigo, who were originally Comicbook/GreenArrow villains in the comics. Vertigo returned in ''WesternAnimation/TheBatman'' but this was in the last season when the show started focusing on assembling the Franchise/{{Justice League|OfAmerica}} and the episode he was in Batman shared with Comicbook/GreenArrow as a supporting role.
* ''WesternAnimation/GreenLanternTheAnimatedSeries'' uses Byth Rok, who is traditionally a foe of Comicbook/{{Hawkman}}.
* ''WesternAnimation/BewareTheBatman'' uses Tobias Whale, who is traditionally an enemy of Comicbook/BlackLightning.
* Big Bad Pete originally appeared in Creator/WaltDisney's ''WesternAnimation/AliceComedies'' before becoming an enemy of WesternAnimation/OswaldTheLuckyRabbit and eventually Mickey Mouse. In the later years of Disney shorts, Pete mainly menaced WesternAnimation/{{Donald|Duck}}, though mainly as a [[JerkAss bullying jerkass]] than a straight up villain. To modern audiences he's probably best known for his role as Goofy's PoisonousFriend on ''WesternAnimation/GoofTroop'', or his role in the ''Franchise/KingdomHearts'' series.
** And speaking of Disney comic book villains: [[MadScientist Emil Eagle]] originally was made up to give Gyro Gearloose a criminal rival, but he later became a recurring character in Mickey Mouse comics by Paul Murry et al., mostly to explain how people like [[ThoseTwoBadGuys Idget the Midget and Dangerous Dan McBoo]] or [[PsychoForHire Pete]] could have sophisticated plans or super-science equipment.
* They aren't really villains, but WesternAnimation/ChipAndDale originally started out as recurring antagonists for [[WesternAnimation/PlutoThePup Pluto]]. Though they still pester Pluto at times, they're far better known nowadays for always bothering DonaldDuck.
* The Mad Thinker and Awesome Android pop up in ''WesternAnimation/IronManArmoredAdventures'' as enemies (and classmates) of Tony and his buddies. In the comics, they're traditionally enemies of the Comicbook/FantasticFour. And then there's DoctorDoom and Comicbook/{{Magneto}}, who both show up in Season 2.
** The 90's ''WesternAnimation/IronMan'' animated series had an episode with the Beetle, who as mentioned above is primarily a Spider-Man villain. The fact that he uses a suit of PoweredArmor like Iron Man and Comicbook/WarMachine allowed him to be depicted as one of Tony's {{Evil Counterpart}}s.
* Taken to the extreme in ''WesternAnimation/{{Ultimate Spider-Man}}'', as part of the show's apparent attempt to be as different as possible to the traditional Spider-Man formula. So far, the show has largely avoided classic Spider-Man antagonists, the only ones showing up after more than ''twenty'' episodes being ComicBook/{{Venom}} ([[spoiler:with Harry Osborn as the host instead of Eddie Brock]]), DoctorOctopus, NormanOsborn (who doesn't become the Green Goblin until the ''season finale'') and Sandman. The other episodes involve either crossover episodes with other heroes involving villains from the guest-star's rogue gallery (Living Laser for Comicbook/IronMan, Loki for [[Comicbook/TheMightyThor Thor]], Zzzax for [[Comicbook/IncredibleHulk Hulk]], Mesmero and Sabretooth for Comicbook/{{Wolverine}}) or villains from other Rogues Galleries who are treated like they were Spider-Man's regular villains (SelfDemonstrating/DoctorDoom, the Frightful Four, Batroc the Leaper, {{Taskmaster}}, Whirlwind, [[ComicBook/{{X-Men}} the Juggernaut]]) As an added twist, some of Spider-Man's foes are now tied to other heroes, such as Kraven being the one who killed ComicBook/WhiteTiger's father, and the Scorpion being from the same mythical city as [[ComicBook/ImmortalIronFist Iron Fist]].
* ''WesternAnimation/HulkAndTheAgentsOfSMASH'' has put the Hulks up against Annihilus, Blastaar, and Ego, the Living Planet, all longtime ''Comicbook/FantasticFour'' headaches. Bonus points for ''{{X-Men}}'' foe Sauron. However, TheManBehindTheMan villain of the series is the Leader, who ''is'' a Hulk villain.
* ''WesternAnimation/AvengersAssemble'' uses Impossible Man, another Comicbook/FantasticFour enemy, as well as DoctorDoom.
* Dick Dastardly and Muttley started out as the enemies of the other racers in ''WesternAnimation/WackyRaces'' but then they gained a new enemy in Yankee Doodle Pidgeon in their own show, ''WesternAnimation/DastardlyAndMuttleyInTheirFlyingMachines''. But then the two started antagonizing ''WesternAnimation/YogiBear'' and the others starting with ''WesternAnimation/YogisTreasureHunt'', then it continues in ''Fender Bender 500'', ''WesternAnimation/YoYogi!'' and the ride ''The Funtastic World of Hanna Barbera''. However due to rights issues they were replaced with Dread Baron and Mumbly and they antagonized Yogi and the others in ''[[WesternAnimation/LaffALympics Laff-A-Lympics]]'' and ''Yogi Bear and the Magical Flight of the Spruce Goose'', but the latter made them sound and act more like Dick Dastardly and Muttley so it's obvious on who they're replacing.
* While he isn't referred to by his real name, the same voice actor, the mirror mask, blue uniform hidden under trenchcoat and yelling "COBRA!" at the end of the episode made rather obvious the man called Old Snake, one-episode antagonist from ''WesternANimation/TheTransformers'', is [[WesternAnimation/GIJoeARealAmericanHero Cobra Commander]].
[[/folder]]

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