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[[quoteright:350:[[WesternAnimation/PhineasAndFerb http://static.tvtropes.org/pmwiki/pub/images/mad_scientists_beautiful_daughter_7.jpg]]]]
[[caption-width-right:350:As you can see, [[UglyGuysHotDaughter she took after her mother]].]]

->''"He's a mad scientist and I'm his beautiful daughter."''
-->-- '''Deety Burroughs''' opening line, ''Literature/TheNumberOfTheBeast'' by Creator/RobertAHeinlein

A traditional character, although something of a DiscreditedTrope these days: a MadScientist almost always has only one child -- a [[TheIngenue beautiful but innocent girl]] in her late teens or early twenties, who loves her father dearly, and whom he has kept cloistered away from the world. Sometimes she has some small doubts about his goals or methods.

When the question of how a shriveled ugly man has a gorgeous daughter comes up, the response is sometimes "[[UglyGuyHotWife she looks like her mother.]]" Or sometimes because [[IWasQuiteALooker he looked better in his youth]].

When the MadScientist is a good guy, the Daughter is not nearly so cloistered, although she is still a prime candidate as a love interest. Sometimes she ends up TheChick or TheSmartGirl in a FiveManBand when a team relies on the Scientist for their {{Phlebotinum}}. This latter version is more common nowadays.

This trope is OlderThanFeudalism, Medea -- and many FairyTale heroines -- being a recognizable form of it, even if it's the mad wizard's beautiful daughter.

Often overlaps with TheUglyGuysHotDaughter. May overlap with DaddysLittleVillain.


[[folder:Anime & Manga]]
* ''{{Anime/Bakugan}}'':
** There is a Mad Scientist's Beautiful ''Granddaughter'' in Alice, granddaughter of Dr. Michael, [[TheDragon The Dragon]] (not literally, the literal dragon is the [[BigBad Big Bad]]. [[spoiler:Somewhat {{subverted}} in that he's not ''exactly'' evil, just heavily affected by the negative energy after an experiment.]]
* ''Anime/TenchiMuyo'':
** Ryoko, daughter of Washuu, is anything but cloistered or innocent. The mad scientist in question is her ''mother'', and Ryoko generally refuses to even admit they're related (even though the resemblance could hardly be more obvious) -- but she still falls for the hero.
** As it is, her mad scientist mother falls for the hero as well.
** Some adaptations of ''Tenchi'' do have Ryoko rather scared of her [[AbusiveParents mother]] because she likes [[GuineaPigFamily using her as a guinea pig.]]
* ''Anime/SailorMoon'':
** Professor Souichi Tomoe, the MadScientist of the third season, has a beautiful young daughter named Hotaru. Who actually happens to be a) possessed by Mistress 9, the season's [[TheDragon Dragon]], and b) unknown even to herself until the end, the heroic MagicalGirl Sailor Saturn. (Oh, and she's also about twelve years old. Most of the time. And in the [[Manga/SailorMoon manga]], a {{cyborg}}. She becomes fully human later though)
** Hotaru is a slight subversion as she's only around 12 when she's introduced her being reborn as an infant and later grows up to around this age, but appears younger (possibly due to change in art style in the last season) complicates her real age. However when she's possesed by Mistress 9 her body grows up into a beautiful young woman.
* In the continuities where Juuzo Kabuto is crazier, Kouji Kabuto from ''Anime/MazingerZ'' fits like the Mad Scientist's Cute Grandson.
** Lorelei -a secondary character from ''Anime/ShinMazinger'' Shiro got a crush on- also fits.
** Lisa, on the other hand, subverted it. Her father -Professor Gordon- was completely sane.
* In ''Anime/RomeoXJuliet'', [[DefectingForLove Romeo Condore Van diMontague]] is the son of the dictator of Neo Verona, the ruthless Leontes Montague, as well as the love interest of Juliet Fiamatta Errs diCapulet, the long-lost heiress of the Capulets. [[spoiler: Actually, there are '''two''' Mad Dictator's Handsome Sons: one is Romeo and the other is [[AloofBigBrother his half-brother Tybalt]], who is still Juliet's cousin since his mom was a Capulet. Or '''three''', if we count Mercutio...]] Dude, that's one messed-up family tree.
* ''Franchise/{{Gundam}}:''
** Aina Sahalin in ''Anime/MobileSuitGundamThe08thMSTeam'' is the Mad Scientist's Beautiful Sister, as well as the test pilot for her brother Ghinias's doomsday device. She eventually decides to turn against him when he goes full-on underpants-on-head crazy and starts shooting at her for trying to negotiate a truce.
** The original ''Anime/MobileSuitGundam'' inverts this with the aging leader of Zeon Degwin Zabi, who's fairly reasonable for a tyrannical dictator with a shady past, at least compared to his more handsome son Gihren, who's basically a [[ANaziByAnyOtherName space Nazi.]] In the end, Degwin attempts to surrender to the Federation, and Gihren wipes him out along with half of the Federation's forces with the [[WaveMotionGun Colony Laser.]]
** From the perspective of "everyone not living in Zeon and consequently fearing the entire Zabi family", Degwin's ''very pretty looking'' youngest son Garma is this played straight.
* Athrun Zala in ''Anime/MobileSuitGundamSEED'' is this note-for-note. He tries to deal with the consequences in the [[Anime/MobileSuitGundamSEEDDestiny sequel]].
* ''Franchise/LyricalNanoha''
** Fate Testarossa fits surprisingly well despite being TheDragon in the first season of ''Anime/MagicalGirlLyricalNanoha''. Beautiful but innocent girl? [[TheWoobie Check]]. Loves her (equally beautiful) MadScientist mother dearly? [[LoveMartyr Check]]. Cloistered away from world? Check. Betray mother at inopportune time? Check, though she still held out for her mother's redemption after helping in StormingTheCastle. Did so because she fell in love with the heroine? [[ShipToShipCombat Depending on who you ask]], [[HeterosexualLifePartners small, kinda check]] or [[HappilyMarried very, very big check]].
** Jail Scaglietti from ''Anime/MagicalGirlLyricalNanohaStrikers'' considers his twelve Numbers as daughters, who see him as their father as well. And the whole family have only good looking members. Only five (actually four[[note]]one of the five is just loyal to the other sister[[/note]]) of them are [[DaddysLittleVillain Daddy's Little Villains]], the other seven pull a HeelFaceTurn after being arrested by the TSAB.
* Played with in ''Manga/MidoriDays'', where MadScientist Shiro Makinoha wants to capture Seiji and Midori so he can experiment on them, and his daughter Nao wants to stop Shiro since she is in love with ... [[SchoolgirlLesbians Midori]].
* ''Manga/FrankenFran'':
** Made more of in the manga. Madaraki Fran is certainly the beautiful daughter of Dr. Madaraki, for a given value of [[CuteMonsterGirl "beautiful"]], and for a given value of [[ArtificialHuman "daughter"]]. She actually [[MadScientist takes after her father]] and generally (almost) [[HalfHumanHybrid everything]] [[BodyHorror that happens]] [[MultipleHeadCase in the manga]] is her fault.
* In ''Manga/DGrayMan'', the ActionGirl Lenalee Lee is the younger sister of Mad Scientist Komui, [[PromotionToParent who raised her]]. Being an active fighter of evil, Lenalee isn't exactly sheltered, but her brother's attempts to [[BigBrotherInstinct protect]] her [[StealthPun Innocence]] is [[KnightTemplarBigBrother the stuff of legends]]; i.e., [[HeavySleeper When all other attempts have failed]], he is [[RunningGag usually]] woken up by being told that Lenalee is getting married, which causes him to immediately wake up and starts freaking out about it.
* Ennis of ''LightNovel/{{Baccano}}'', creation and "daughter" of the 1930 arc's BigBad, Szilard. She does twist it slightly in that [[spoiler: she betrays him not for TheHero, Firo (who, at that point, she thought was dead), but for the [[PluckyComicRelief comic]] OutlawCouple, Isaac and Miria]]. There's also the daughter of MadScientist and unapologetic ManipulativeBastard Huey Laforet, Chane Laforet, who falls in love with the AntiHero and professional assassin, Claire Stanfield. This ends up being subverted in that [[spoiler:Chane doesn't betray her father for him - instead, Huey just hires Claire.]]
* ''Anime/NeonGenesisEvangelion'':
** Ritsuko and Misato, the former of which takes up the mad science herself, but has yet to procreate. Shinji himself may count as the Mad Scientist's [[{{Bishonen}} Cute-looking]] Son, depending on your view. One of the few examples to have mad science on ''both'' sides of his family.
** Asuka. Beautiful? Check, Smart? Check, Love Interest? [[FlameWar Check]], Loves MadScientist mother dearly? Check. Mother is insane? Check ([[spoiler:Unless you call: A) Reattempting an experiment that ATE the previous person. B) hanging yourself (After losing what sanity you had in said experiment) so that your daughter would be the first person to find your body. Sane]])
** Although Rei is not biologically related to Gendo, she is very much introduced this way in a more archetypical fashion than any of the above (socially inexperienced quiet girl, the only one Gendo shows anything resembling humanity around, protagonist gets interested in her, gradually comes to doubt Gendo's methods and betrays him for the protagonist, etc.)
* ''Huge'' subversion in ''Anime/MobileFighterGGundam''. [[spoiler: We thought that main character Domon Kasshu was the Mad Scientists's Handsome Son... but he wasn't. Then we thought he was the Magnificent Bastard's Handsome Younger Brother... Guess what. He wasn't. His partner Rain Mikamura, on the other hand...]]
* ''Manga/GetterRobo'''s Michiru counts as this in several continuities.
* ''Anime/StarBlazers'':
** Dubbing created one of these, with Princess Invidia in the second series, rewritten to be Zordar's daughter instead of a lover. Because of the prevalence of this trope, the change was fairly plausible.
** The Japanese manga omake "The Eternal Story of Jura", about Desslok's daughter. The pretty daughter part of it is played pretty straight; even though she's past the doubting stage about his methods and knows he's evil, she loves him. The betrayal was also done by Jura's mother, not Jura, but Jura condoned it.
* ''Manga/SoulEater'': Medusa's [[AmbiguousGender child]] Chrona [[spoiler:joins the heroes, albeit unwillingly at first. They become affectionate towards Maka, and to a lesser extent the other protagonists, but are kidnapped back and driven (more) insane. They do eventually betray Medusa, but remain an antagonist until the end of the series.]]
* ''Manga/FullmetalAlchemist'': Riza Hawkeye is the Crazy Alchemist's Beautiful Daughter.
** Not to mention Nina. Sure, she is just five and anything but a love interest to the heroes, but she is cute, adorable, adores her State Alchemist Dad who shelters her [[spoiler: and maybe would have grown into a very cute young woman if her father hadn't used her for chimera experiments that ultimately doomed her.]]
* Saiko Waitazuki from ''Anime/SupercarGattiger'', though her father isn't mad, but serves as the team's lead scientist. She, of course, ends up as TheChick in their FiveManBand.
* ''LightNovel/{{Durarara}}'' has Shinra as the Mad Doctor's Handsome Son. He's... slightly more normal than his father Shingen, but he didn't get away without a screw or two loose.
* Minato Sahashi is a male example, in ''Manga/{{Sekirei}}''. His mother is the head scientist of the Sekirei Plan, and leaves him innocent and oblivious to her work, as well as the identity of his father. [[spoiler: It is, of course, BigBad Minaka]]. Higa mistakenly believes the younger Sahashi sibling, Yukari, to be this as well. She's [[DaddysLittleVillain not]], and sets fire to his penthouse on her way out.
* ''Manga/{{Cyborg 009}}'':
** Dr. Isaac Gilmore is child-less, and he subverts this by gaining the Cyborgs as his adoptive children ''after'' he stops being a MadScientist. [[spoiler: And there's the little detail that he was among the {{mad scientist}}s who ''created the cyborg team'' [[TheAtoner in the first place]].]]
** Also subverted by Cynthia Findor, since her father ''is'' doing really crazy experiments [[ReluctantMadScientist but NOT willingly]]. In fact, Black Ghost kidnapped ''her'' to reinforce their intentions to keep Dr. Findor under their thumb.
* ''Anime/KillLaKill'': Subverted with Ryuko, since her father Isshin was a perfectly sane man and the BigGood of the story, despite his eccentric appearance. [[spoiler:Double Subverted when it's shown that her mother is [[KnightOfCerebus Ragyo]], who experimented on and threw her away as a child]]. [[spoiler:This also means that Satsuki counts, as well]].
* ''Franchise/{{Naruto}}'': [[spoiler: It turns out that Mitsuki is the Mad Scientist Orochimaru's Handsome Son. Mitsuki says he respects his parent, but thankfully, doesn't seem to have inherited Oro's twisted personality and madness.]]
* ''Manga/TokyoGhoul'' has Akira Mado, the stunning daughter of "Quinque Maniac" Kureo Mado. She shares her father's passion for Quinque, and works closely with the Research division in her spare time. She inherited her looks from her late mother, and becomes Amon's new partner and LoveInterest after her introduction.
* Anime/{{Ponyo|OnTheCliffByTheSea}} is the prepubescent form of this: a Mad Sorcerer's Adorable Daughter.
* ''Manga/MadeInAbyss'' has Prushka, [[spoiler:the adoptive daughter of the White Whistle Bondrewd the Novel]]. Unlike most examples, her awareness of her father's actions is fairly significant. The degree of isolation that she lives in is enough for her to be incapable of seeing anything wrong with it, though, [[spoiler:to the extent of seeing the failed Praying Hands as a tragic necessity and being unbothered when she discovers her father's [[PoweredByAForsakenChild Cartridges]] ]].

* ''Literature/YoungBeichan'' is a rationalized version of the FairyTale -- DoingInTheWizard was applied -- but the heroine still can be recognized as this trope.

* ''ComicBook/{{Shazam}}'':
** Doctor Sivana, nemesis of Captain Marvel, has a daughter with the painfully obvious name "Beautia"; naturally she sides with the Captain against her father.
** In this case Sivana also has a good/handsome son ''and'' an evil/ugly daughter and son, who are perfectly happy to help their dad go up against Captain Marvel.
** Though in more modern works, his handsome son and daughter are portrayed as self-centered, spoiled brats while his ugly, brilliant children are their mother's [[TheUnFavorite un-favorites]] and running their own experiments just to impress their mostly absent father.
* Talia, the daughter of Ra's Al Ghul in the ''Franchise/{{Batman}}'' comics. Her loyalty to her father is... complicated. In the comics, it is usually unwavering. She foils his [[spoiler: 'destroy the written word' scheme]], a lackey shoots her in the leg and the lackey is fed to lions.
** In the video game, ''VideoGame/BatmanArkhamCity'', it's played darkly [[spoiler:[[InTheBack when he makes a move of threatening Batman with her life]] if he does not kill him]]. This results her in leaving him [[spoiler:after Batman saves her]].
* Recently, Sofia Branch turned up in ''ComicBook/BatmanTheBlackMirror'' as the manager of Gotham's fastest growing bank. Who is Sofia Branch? She's the daughter of Tony Zucco, the killer of Dick Grayson's parents.
* Princess Aura, daughter of Ming The Merciless, in the various versions of ''ComicStrip/FlashGordon''.
* Alicia Masters of the ''ComicBook/FantasticFour'', stepdaughter of the Puppet Master.
* The Yellow Claw, a Creator/MarvelComics CaptainErsatz for Fu Manchu, had a Beautiful Grandniece, who repeatedly betrayed him due to her love for FBI agent [[ComicBook/AgentsOfAtlas Jimmy Woo]]. Eventually, he put her in [[HumanPopsicle suspended animation]] until he could fuse her soul with that of a suitably power-mad Egyptian princess. Really.
* Sorta done in ''ComicBook/WerewolfByNight''. When traveling to an island for a cure for his werewolfism, Jack meets the local mad scientist Miles Blackgar and the beautiful daughter Marlene. Marlene helps Jack at first and doesn't even fear him when he's in wolf form, but after he knocks out her father she [[spoiler:turns out to have a Gorgon gaze and turns Jack to stone for grabbing her arm.]] She also seems to help Jack more out of self preservation, since she mentions that her father ultimately intended to experiment on her, [[spoiler:to cure her gaze of stone.]]
* Since ComicBook/{{Magneto}} also is a scientist, the ComicBook/ScarletWitch and her (on and off, currently on) half-sister Polaris qualify. Wanda looks [[UncannyFamilyResemblance almost exactly like her mother]].
* Laura "ComicBook/{{X 23}}" Kinney is this. Her creator, Dr. Sarah Kinney, was described as the foremost expert on mutant genetics and was hired by the Facility after her proposal to clone ComicBook/{{Wolverine}}. Despite the ethics of the project, Sarah's interest was purely ForScience, directly likening the idea of cloning a ''mutant'', when mainstream science had only ''just'' cracked cloning sheep and cats, to [[AGodAmI godhood]]. All this knowing full well that the child would be raised to be a LivingWeapon heading in. Laura herself is frequently described as Sarah's spitting-image (explained by some writers as Sarah using her own DNA to stabilize the sample taken from Wolverine), and it's made quite clear Laura is intended to be a quite beautiful young woman.
* Dr. Zabo/Mr. Hyde doesn't have much in the looks department (and his inside matches is outside), which is probably why he frequented prostitutes. His daughter, Daisy Johnson/Quake is consistently described as gorgeous, and is one of SHIELD's real lookers, and can't seem to do anything in civilian mode without someone hitting on her.
* Linea in ''ComicBook/WarlordOfMars'' is a Black Martian noblewoman whose father is a mad priest of Issus that wants to activate a DoomsdayDevice that will wipe out all life on Mars (since the defeat of their people at the hand of the Red Martians, he would rather destroy the planet than let themselves be ruled by lesser races). Its revealed that [[spoiler:her grandmother was Issus herself, and she qualifies as a Mad Goddess' Beautiful Granddaughter too]].
* ''ComicBook/NewGods'': Orion's wife Bekka is the daughter of Himon, the scientist that created the Mother Box and was even forced to work for [[EvilOverlord Darkseid]]. During the "Death of the New Gods" its implied that he became a SerialKiller and started murdering New Gods left and right, regardless if they were from Apokolipis or New Genesis. [[spoiler:Turns out to be a RedHerring, the actual culprit is Infinity Man]].

[[folder:Fairy Tales]]
* ''Literature/SnowWhiteFireRed'':
** She regards herself as an ogress's daughter -- it's never explained whose daughter she is, if not -- but runs off with the prince.
** Similarly in ''Anthousa, Xanthousa, Chrisomalousa'', and in ''[[http://www.surlalunefairytales.com/rapunzel/stories/fairang.html The Fair Angiola]]'' where she's a foster daughter
** In ''[[http://www.mythfolklore.net/andrewlang/328.htm Geirlug The King's Daughter]]'', she helps him flee her stepmother.
* In ''[[http://www.surlalunefairytales.com/authors/grimms/113twokingschildren.html The Two Kings' Children]]'', the daughter advises the prince how to carry out her father's ImpossibleTask.
* Literature/{{Prunella}} is helped by the witch's handsome son.

[[folder:Fan Works]]
* ''Literature/HarryPotter'':
** In the French fandom, Voldemort was supposed to have a daughter called Ange (false rumors copied on every fan site). She was rumored to enter Hogwarts in book five. Actually it was one of many false rumors that were copied from one French Harry Potter fansite to another.
** If fanfiction is anything to go by, Voldemort has about a million MarySue daughters. It seems he mostly sends them to Hogwarts to kill Harry only for them to (of course) fall in love with Harry. Expect her to show up openly using "Riddle" as her surname with the author acting as though we won't see TheReveal coming a mile away. If it's explained who her mother is, it will probably be Bellatrix.
** For awhile, it was rumored that Snape was Luna Lovegood's father, which would have kind of fit this trope. Too bad the identity of Luna's father was firmly established from the moment of her first appearance. Still Creator/JKRowling ended up [[http://www.jkrowling.com/textonly/en/rumours_view.cfm?id=35 refuting this on her website.]]
* Globally subverted in the forum story ''FanFic/TheMadScientistWars''. In the story, the trope is reimagined as the "Mad Scientist's Beautiful Daughter ploy", in which the daughter will ''always'' pretend to help the hero escape, then drop him into some even nastier bit of trouble. Apparently, it's hard on the heroes and fun for the daughters.

[[folder:Films -- Animation]]
* ''Disney/BeautyAndTheBeast'' utilizes this with Belle and her father, with alterations in the form of the 'mad scientist' being a good person (more of a BunglingInventor, really) and the fact that plot starts because the mad scientist's daughter is ''loyal'' to him.
* ''WesternAnimation/TheNightmareBeforeChristmas'':
** Dr. Finklestein and his beautiful artificial creation Sally. He's [[OverprotectiveDad smotheringly overprotective]], to the point that she has to poison him repeatedly to get a simple night out. Also, Finklestein is actually on friendly terms with Skellington -- really, the person he antagonizes most is Sally.
** Interestingly, in an alternative ending, [[spoiler: Finklestein being on friendly terms with Jack is subverted with Finklestein [[TheManBehindTheCurtain being]] ''Oogie Boogie'', in order to teach Sally about [[GreenEyedMonster choosing Jack over him]], making the Finklestein/Sally relationship seem more carnal.]] This, along with canonically the next person the Doc creates to replace Sally seems to be a wife ([[ScrewYourself who looks exactly like him and even shares half his brain]]), has quite a few fans calling [[AlternateCharacterInterpretation bullshit]] on the "beautiful daughter" explanation.
* For ''WesternAnimation/DespicableMe'': We have the cutest daughters, Margo, Edith, and Agnes.

[[folder:Films -- Live-Action]]
* In the 1996 film adaptation of ''Film/TheIslandOfDoctorMoreau'', they give the title doctor a beautiful cat-woman daughter -- who conveniently slides into love interest for the hero Douglas.
** ''Film/IslandOfLostSouls'' started the cat-woman daughter of the mad scientist.
* As [[Film/TheRockyHorrorPictureShow the song]] goes, "Anne Francis stars in ''Film/ForbiddenPlanet''", based on ''Theatre/TheTempest'', as Altaira, the Beautiful Daughter of the Mad Scientist, Dr. Morbius.
** Actually a semi-aversion, though, since Morbius specifically denies being a mad scientist, and is ultimately proven to be misguided rather than crazy.
* Occasionally appearing in a ''Franchise/{{Godzilla}}'' movie as well, most notable being Katsura from ''Film/TerrorOfMechagodzilla'', cyborg daughter of Dr. Mafune. Also, it is worth mentioning that Emiko Yamane, heroine of the original ''Film/{{Gojira}}'' film, was TheProfessor's daughter.
* Natalie Connors from ''Film/AgentCodyBanks'' fulfills this trope as if the writer had been reading this Wiki.
* Freder Frederson of ''Film/{{Metropolis}}'' is a Slightly Unhinged Dictator's Handsome Son. Incidentally, the MadScientist was in love with Freder's mom.
* In ''Film/{{Willow}}'', Sorsha plays the Mad Sorceress's Beautiful Daughter. With some help from a LovePotion and HeelFaceTurn from her mother.
* Tara from ''Film/AttackOfTheKillerTomatoes'' fits the trope almost perfectly (right down to the betrayal part), except for having been created by her mad-scientist father to be a cook, house-cleaner and sex-slave. You may {{squick}} if you wish.
* ''Film/{{Bullshot}}'' (1983). Rosemary Fenton, though her father is more of an AbsentMindedProfessor who's being forced to work for the villain. She does fall in love with the hero though.
* Cally in ''Film/{{Doomsday}}''. Notable mostly because her father's paranoia over her brother's rebellion causes her to fear for her life from him, justifiably as he winds up blaming her for bringing in "impurity". Also notable because the main character is a woman, so Cally winds up a sort of ImpliedLoveInterest for a more minor character.
* ''Film/{{Blade}}''. One of the vampire scions helps bring down her house.
* Helen Kokintz in ''Film/TheMouseThatRoared'', except that her father is not mad.
* Nanelia in ''Film/BattleBeyondTheStars'' is a fairly archetypal example.
* Dione, the daughter of Melanthius in ''Film/SinbadAndTheEyeOfTheTiger'' is an example of the daughter of a good scientist. And he is not really mad, just a little batty.
* ''Film/YoungSherlockHolmes''. Professor Waxflatter is more eccentric than mad, but his daughter is quite beautiful.
* The learned Rabbi of the silent movie ''Film/TheGolem'' has his beautiful daughter Miriam, who promptly falls in a forbidden love with the christian Knight Florian. Their romance turns out to be a RedHerringTwist, though.
* Amy Szalinski in ''Film/HoneyIShrunkTheKids'' is an example of the daughter of a good guy mad scientist, Wayne Szalinski. However, she's not an only child, as she has a younger brother, Nick, and the sequels include another younger brother named Adam. She is, however, the only girl.
* Elsa Frankenstein from ''Film/TheGhostOfFrankenstein'' is Dr. Wolf Frankenstein's beautiful daughter. She has a more prominent role as the titular MadScientist in the sequel ''Film/FrankensteinMeetsTheWolfMan''.
* Kyra in ''Film/SinbadOfTheSevenSeas'' is the daughter of the CloudCuckooLander inventor and "wizard" Nadir, and ends up as Sinbad's LoveInterest.
* In ''Film/TheImaginariumOfDoctorParnassus'', Valentina is this to the doctor (who's not technically a scientist, but rather a mystic who made a DealWithTheDevil).

* The above two comic book examples both draw elements from Sax Rohmer's ''Literature/FuManchu'' mythos, including the Beautiful Daughter; however, Fu's own daughter Fah Lo Suee was a full-fledged FemmeFatale (or even [[TheVamp Vamp]]) rather than a cloistered innocent -- just as likely to turn against him, but because she wanted to take his job....
* A LampshadeHanging: in Creator/RobertAHeinlein's novel ''Literature/TheNumberOfTheBeast'', Deety Burroughs introduces her father and herself to her future husband Zeb Carter by declaring, "He's a Mad Scientist, and I'm his Beautiful Daughter." Zeb, in his role as the {{Narrator}}, comments immediately on the cliché.
* Hawthorne published ''Rappaccini's Daughter'' in 1844. This story has an [[PoisonousPerson interesting twist]] on the trope.
* Though Sloan from the ''Literature/InheritanceCycle'' is more JerkAss than BigBad ([[spoiler: though he does betray his village in Book 2]]), his daughter Katrina might count.
* Creator/PhilipJoseFarmer gleefully inverted this trope with "The Beautiful Scientist and her Mad Daughter."
* Children's author Allan Ahlberg wrote a notably creepy poem called ''The Mad Professor's daughter''.
* Subverted in Alexander Belayev's ''The Air Seller'': while Nora Engelbrecht is certainly that trope, her father turns out to be not really mad. He is forced to serve the BigBad Bayley, who secretly threatens to murder Nora if Prof. Engelbrecht will not help him with his DoomsdayDevice. At the end, [[spoiler:Nora commits suicide to free her father and save the world]].
* In the ''Literature/{{Animorphs}}'' series, the Andalite Estrid fits this outline fairly well, although she is only a protege of the Mad Scientist character, Arbat. (Ax speculates that Estrid may be Arbat's niece, but she is no relation at all.) Arbat is a kind of alien GeneralRipper who intends to deploy a biological weapon (which he designed with help from Estrid) that will destroy both the Yeerks that are invading planet Earth--and probably the human race along with them. When Estrid meets the Andalite main character Ax, they hit it off and she becomes Ax's GirlOfTheWeek. Estrid was initially a WellIntentionedExtremist who agreed with Arbat's goals, but she became convinced it was wrong and helped to defeat Arbat.
* ''Literature/TheFirstLaw'' plays this straight with Bayaz and Tolomei. [[spoiler:Then, in a brutal twist, it is revealed that Bayaz was the one who threw her from the tower, not her MadScientist father, in order to hold a monopoly over the secrets which she possessed.]]
* The heroine of Creator/EdgarRiceBurroughs's ''Literature/TheMonsterMen'' is the daughter of a mad scientist who is producing the title Monster Men -- he hopes to marry her off to one. (He gets better, though.)
* The likeliest [[TheIgor "tradithion"]] to spawn the beautiful [[CuteMonsterGirl Igorinas]] in the Literature/{{Discworld}}.
* ''Literature/HeraldsOfValdemar'':
** The ''Mage Winds'' trilogy features Nyara, biological daughter and sexual/magical plaything of BigBad Ma'ar in his latest [[GrandTheftMe incarnation]]. She "[[TheMole attempts escape]]" several times, but her HeelFaceTurn doesn't actually occur until Skif [[HeroicSacrifice nearly dies]] to save her.
** Lackey's retelling of ''Theatre/SwanLake'', ''Literature/TheBlackSwan'', makes Odile into one of these. Her father expects her to betray him, which is painfully ironic since she is a textbook example of a [[WellDoneSonGuy Well Done Daughter Girl]] -- the HeelFaceTurn starts because she starts actually spending time with the swans, instead of just looking down on them. The supernatural control, ie him using her as "Odette" ''without her permission'', is just the last straw that makes her realize his true character. [[spoiler: And her turning on him is hardly subtle - ''she's'' the one to kill him, after all.]]
* In ''Literature/ASongOfIceAndFire'' [[TheCaligula King Aerys]] managed to beget a ridiculously good offspring (well, if you don't mind Viserys' mental health). Rhaegar was always in the collective imagination (don't mind [[{{Archenemy}} Robert Baratheon]]) the Mad King's handsome and noble son, who'd have made a great king some day. Daenerys is as well a bright young woman who before hitting 16 is already considered WorldsMostBeautifulWoman and tries hard to not make the same mistakes her family did.
* Elizabeth Faulkner, the daughter of an irrational Elizabethan steam-engineer, in ''Phra the Phonecian'' by Edwin Arnold.
* Georgette Cuvelier in Harry Dickson's Adventures. The young woman turns out to be the daughter of [[spoiler: Pr Flax]], a former archenemy of the hero. Played straight in that she has a huge crush on Harry Dickson. Subverted in that [[spoiler: she remains evil and would rather avenge her father and die than surrender]].
* Angie Mitchell in Creator/WilliamGibson's ''Literature/SprawlTrilogy'', particularly in ''Literature/CountZero''.
* [[PlayingWithATrope Played with]] in Theodora Goss's short story [[http://strangehorizons.com/2010/20100118/daughter-f.shtml "The Mad Scientist's Daughter,"]] which also namedrops a who's who of iconic [[MadScientist Mad Scientists]] in fiction.
* Andre Caroff's ''Madame Atomos'' was a vengeful scientist with a hard-on for radioactive zombies and madness beams. She [[CloningBlues created a younger version of herself]] named Mie as a backup plan, who promptly turned on her after falling for Atomos's nemesis, Smith Beffort of the FBI.
* In the short story "The Girl of My Dreams" by Hilary Ayer (a crossover between the ''Torg'' and ''TabletopGame/{{Paranoia}}'' roleplaying universes), this is not just a trope, but a law of nature.
-->'''Professor Thistlebottam:''' I was a Scientist, therefore I had to be either Sinister or Mad. I seem to have been cast as Mad, therefore by the laws of the cosm, I had to have a Beautiful Daughter.
* In ''The Bride of the Wind'', the eponymous character's father was a scientist, and she said to be beautiful, if unique-looking.
* In one of the ''Schaduw'' (Shadow) detective/policiers by Havank, a Dutch writer, the eponymous main character encounters the most beautiful young woman he's ever seen. As this happens in a remote castle somewhere in Normandy, she can't be anything but a MadScientist's daughter. The guy has engineered spiders to be a bit bigger and powerful (the biggest eats a grown pig in a couple of seconds), but he's disappointed their brains have not kept up. But now this human brain has come walking in ... perfect. The kicker: he's named his daughter [[UnfortunateName Aranea]] (could have qualified as a MeaningfulName, but she herself tries to keep herself away from his shenanigans).
* Miranda Taligent from the SteamPunk novel ''Literature/TheDreamOfPerpetualMotion''. She eventually goes mad herself.
* More or less gender-inverted in ''Literature/MistbornTheOriginalTrilogy'' by Elend Venture, who is the handsome but innocent son of EvilOverlord Straff Venture. Ends up DefectingForLove.
* Invoked in Creator/GeneWolfe's "The Last Thrilling Wonder Story": the author is deliberately writing a pulp story, so ''of course'' the scientist has a beautiful daughter, and the protagonist knows he will love her before they even meet.
* Subverted in ''Literature/DieAlchimistin''. Aura Institoris is certainly beautiful, and kept cloistered in her castle and then at the institute at her father's wish, and her father in an alchemist who is most definitely not all there, and she is (in the beginning) his favorite child, but [[spoiler:it turns out that he was maintaining their bond and keeping her away from theyo turns out that Aura's mother was her father's daughter as well]].
* In ''Literature/TheReefsOfSpace'', Donna Creery is the daughter of the Planner of Earth, chief executive of the [[MasterComputer computer-controlled]] dictatorship which rules Earth, but she's sympathetic to Steve Ryeland, the scientist who's been arrested for reasons he doesn't understand. She eventually helps him escape when he ends up facing a death sentence.
* In Fyodor Sologub's ''The Poisoned Garden'', the Professor's daughter, only called the Beauty, is an example. He uses her to lure young men into his garden and poison them in revenge for his ancestor's death.
* The title institution of ''TheSecretsOfDrearcliffGrangeSchool'' is basically a finishing school that turns mad scientist's beautiful daughters into femmes fatales to help them snag a good superhero (or villain) husband. While the viewpoint character ''isn't'' this trope, many of the other students have diabolical masterminds as children.

[[folder:Live-Action TV]]
* In the ''Series/{{Angel}}'' episode "Guise Will Be Guise", plays this straight - [[InSpace with MAGIC]]! In order to save [[DamselInDistress Cordelia]], [[NonActionGuy Wesley]] is [[MostDefinitelyNotAnImpostor forced to impersonate]] Angel and ends up playing bodyguard to an evil Warlock's beautiful daughter. HilarityEnsues.
* Play straight in ''Series/DenjiSentaiMegaranger'' which Hinelar had beautiful daughter name shizuka.
* ''Series/StarTrekTheOriginalSeries'':
** Such as Rayna, Flint's "ward" from "Requiem for Methuselah". He was neither evil nor mad, he just didn't want his privacy to be disturbed (and for good reason).
** Inverted in "Conscience of the King", where it is the daughter who is the mad one, trying to protect her accused father (he wasn't squeaky clean either tho).
* And then there's Tora Ziyal from ''Series/StarTrekDeepSpaceNine'', the innocent daughter of Gul Dukat who always tried to give her father the benefit of the doubt. It didn't end well for her: [[spoiler: she dies a pretty pointless death at the hands of Dukat's [[TheDragon Dragon]] when even she was forced to accept that her father had run out of excuses for the way he behaved and the decisions he took. Always mentally unstable at best, her death was what snapped the last remaining thread of sanity Dukat had ever possessed]].
* Alex on ''Series/{{Lost}}'' fits this role, giving information learned from her adoptive father to the crash survivors. Different because it was, perhaps, simply a form of teenage rebellion against him, especially his treatment of her boyfriend.
* Her dad isn't really a Mad Scientist (he employs them instead), but Elle from ''Series/{{Heroes}}'' works too, down to flirting with the protagonist (Peter). Of course, she's pretty damn evil, and her way of flirting is to electrocute him a little bit each day to make him want it, but still....
* Ziva David in ''Series/{{NCIS}}'' could be considered this, to a point. Her father could be viewed as a WellIntentionedExtremist but he's more likely just a {{Jerkass}}. Gibbs himself points out to Ziva that her father, despite being the director of Mossad, is dirty and sometimes crosses the MoralEventHorizon into pure, selfish evil. Her response? Sometimes she's on his side, sometimes she's on Gibbs... and now she seems to have crossed permanently into Gibbs' camp by [[spoiler:quitting Mossad and terminating all contact with dear old dad.]]
* ''Series/{{Fringe}}'': Male example: The series has a female lead and the son of a MadScientist who doesn't exactly approve of his father's activities. By the end of season 2 romance between Peter and [[TheHero Olivia]] is canon.
* Parodied in an episode of ''Series/{{The Monkees}}'' where they spend the night in a mad scientist's house. Micky opens a door and finds a woman standing there:
-->'''Micky:''' Who are you?\\
'''Woman:''' I'm the doctor's beautiful daughter.\\
'''Micky:''' Well, what do you have to do with all this?\\
'''Woman:''' Nothing, I'm in the sequel.
* Lampshaded in ''Series/DangerUXB'' when Lieutenant Ash delivers a defused bomb to Dr Gillespie and his daughter Susan, who are building a HeathRobinsonMachine in their backyard for steaming explosives out of unexploded German bombs. Ash later reports to his superiors on the phone, deriding the device as completely impractical and describing Gillespie as the proverbial MadScientist who even has the requisite beautiful daughter said daughter has of course [[RightBehindMe just entered the room behind him]].
* ''Series/{{Spooks}}'': Ros Myers isn't exactly sweet or innocent, but she ''does'' prove to be the weak link in her father's WellIntentionedExtremist conspiracy.
* ''Series/DoctorWho'':
** In "[[Recap/DoctorWhoS4E9TheEvilOfTheDaleks The Evil of the Daleks]]", Maxtible and Waterfield have one innocent, beautiful daughter each: Ruth and Victoria, respectively. Victoria even becomes a companion.
** In "The Web of Fear", Professor Travers has one, Anne Travers, who is also a MadScientist herself. She and Victoria appear to bond somewhat over the similarities between their fathers.
** Mad Scientist's Beautiful Granddaughter: Susan Foreman, the first Companion of William Hartnell's Doctor. While she is his granddaughter, they have this exact relationship, and she was obviously intended to fit this trope (until the series began to GrowTheBeard and the Doctor became something much, much odder than simply the mad scientist he was conceived as).
** The Literature/EighthDoctorAdventures kind of introduce Susan's mother, in the form of a young girl whom the Doctor adopts who seems to be Gallifreyan. She happens to be named [[Theatre/TheTempest Miranda]] and happens to have that beautiful-but-[[TheIngenue sheltered]]-and-ObliviousToLove thing going on (at first), and the Doctor has a few scenes of doing [[ScienceHero sciencey laboratory stuff]] throughout the book.

[[folder:Myths & Religion]]
* From Myth/ClassicalMythology: Medea of "Jason and the Golden Fleece" fame -- she is the daughter of King Aeëtes who sets seemingly impossible tasks for TheHero Jason before he can have the fleece. Although Medea herself is evil and out to serve only her own interests; she eventually betrays Jason, too, although not before killing her own brother ''and'' her own children. However, she only killed her children intentionally if you rely on the [[Theatre/{{Medea}} Euripides version]] of the myth. Earlier versions had it either being an accident, or murder by ''other people''. She also only killed her brother to save Jason from her father. In fact, the only people she ''didn't'' kill for Jason, according to the earlier myths, were the princess of Corinth, whom Jason abandoned her for, and the King of Corinth, who died trying to save his daughter.
*** Even the Euripides version assigns most of the actual blame for how things worked out to Jason's heroic flaw of ambition, and presents her desire to destroy the legacy that she'd lost everything to create for him (the fact that she did most of the work in her section of the Argonauts story is lampshaded thoroughly) is treated less as the sinister kind of evil and more the righteous rage of a betrayed demigod whose strained patience at being slowly discarded finally snapped.
* Theseus and Ariadne of Chrete. Ariadne betrayed her father and her people for Theseus and his friends. Theseus and Ariadne fall in love, but Theseus comes up with an interesting way to break it off -- leaving Ariadne stranded in an island in the middle of nowhere because of a dream.\\
Some myths explain that the dream was sent by a god (more exactly, Dionysius [[TheHedonist the god of wine, theater and fertility]]), and basically was a "Hands off my woman" message. It may have included a fairly detailed explanation of why one does not want to play the RomanticFalseLead ''to a god''. He picked her up after Theseus decided to wisely drop her off; one hopes he told her ''why'' instead of just shoving her overboard at the suggested drop site and fleeing.\\
Also, Theseus soon gets some LaserGuidedKarma for abandoning Ariadne [[KickTheDog like he did.]] He had promised to use white sails on his ship to let his beloved father Aegeus know he was alive... he forgot to change his black sails, Egeus saw that and was DrivenToSuicide. And not to mention what happened when he got involved with Ariadne's ''sister'' Phaedria, too...

* OlderThanSteam: Miranda, the daughter of the sorcerer Prospero in Creator/WilliamShakespeare's ''Theatre/TheTempest''. She fits the trope, except for the betrayal part. Prospero's actually for the match, he just wants to make sure Ferdinand's love-at-first-sight won't end up as out of sight, out of mind.
* Odile from ''Theatre/SwanLake''. Daughter of the evil sorcerer, he sent her to seduce the hero.
* Though not quite a mad scientist, Caldwell B. Cladwell's daughter (appropriately named Hope) in ''Theatre/{{Urinetown}}'' certainly fits. It is often remarked upon how beautiful she is, she has no idea how cruel her father is, and, of course, falls in love with Bobby Strong. Also a good example of a DaddysGirl.

[[folder:Video Games]]
* ''VideoGame/{{Disgaea 2|Cursed Memories}}'' features Rozalin, the Evil Overlord Zenon's Beautiful but Spoiled Daughter who's contractually bound -- much to her annoyance -- to follow the [[IdiotHero ridiculously impulsive hero]] on his quest to kick her father's ass. While she starts out as outright murderous, things do start to change when she starts realizing that daddy doesn't seem to want her back safely so much as he wants her out of the way. Then again, [[spoiler: he's not actually her father. Or [[SamusIsAGirl the real Overlord Zenon]], for that matter...]]
* ''VideoGame/SuperRobotWars'':
** Due to the traits of [[MadScientist Lemon Browning]], Lamia Loveless fits here, as she is the creation of Lemon that eventually got her own conscience and rebels against her creator. She's not the only daughter, however. Lemon also has another daughter and another son (though they did not directly rebel)
** A Mad Dictator's Handsome Son variation exists in ''VideoGame/SuperRobotWars Destiny'', the male protagonist Joshua Radcliff. He did respect his father in a way, but in the same time, he dislikes his father for being too workaholic and bordering a MadScientist, because he experimented Rim mercilessly to further his research/job, uncaring that she develops a SplitPersonality afterwards. And guess what, [[spoiler:said father got killed and absorbed into the BigBad Perfectio and Joshua ends up killing his father to amend his wrongdoings.]]
** Lune Zoldark, daughter of the original BigBad MadScientist Bian Zoldark, who eventually joins the good guys because she got a crush on one of the heroes, Masaki Andoh. Her defection from her father and falling in love are backwards, (she meets up with the good guys when she's coming back to fight her father, who she thinks has been corrupted by power, and [[spoiler: ''after'' they've already defeated him]]), but she's probably one of the best examples.
* ''Franchise/FireEmblem'' has several:
** ''Thracia 776'' has Sara, who is the adorable-looking granddaughter of [[spoiler: the mad priest Manfloy.]]
** ''Blazing Blade'' has ''both'' the Handsome Son (though "younger" than most, in a sense) and the Beautiful Daughter. [[spoiler: Ninian and Nils are the children of the BigBad of the game, the Dark Druid Nergal. ]]
*** Not to mention another beautiful -- okay, ''[[{{Moe}} cute]]'' -- daughter in Sonia's (adopted) child, Nino. [[spoiler:Sonia is actually one of Nergal's morphs]].
** In ''VideoGame/FireEmblemAwakening'', [[spoiler: the ''PlayerCharacter'' is the runaway son/daughter of [[UglyGuysHotDaughter the very weird-looking]] [[TheDragon Dragon]], [[EvilSorcerer Validar]]. Even when using the older builds for the character (especially the 'older male' one), s/he is always said to be good-looking by the other characters.]]
* ''VideoGame/JadeEmpire'' has Silk Fox, the insane emperor's beautiful daughter.
* ''Franchise/MassEffect'':
** Liara is the daughter of [[TheDragon Matriach Benezia]], and it is possible to romance her whether your character is man or [[GayOption woman]]. [[spoiler:Benezia's "madness" isn't her fault, though. It's somewhere between {{Brainwashed}} and MoreThanMindControl in her case.]]
** In ''VideoGame/MassEffect2'', we discover [[spoiler:Tali's father Rael]], who performs some ethically questionable experiments on [[spoiler:geth]], even if he is not evil ''per se''.
** Miranda Lawson is a subversion, since her father clearly ''intended'' her to to be this, having created her in a lab [[OppositeSexClone from his own DNA]] to create the ''perfect'' daughter and secure his dynasty. Naturally, Miranda had ''[[RebelliousPrincess other]]'' ideas.
* ''VideoGame/HalfLife'':
** There's also Alyx Vance, daughter of relatively stable physicist and teleporter scientist Eli Vance. Given that he worked in the Lambda complex and was therefore at least partially responsible for the events which brought the Combine to earth, he probably counts as a little bit mad.
** Next to [[GoodIsNotNice Doctor Magnusson]], Eli is arguably the most sane among the Black Mesa survivors. Alyx's "uncle" and family-friend Isaac Kliener definitely fits the role of Mad Scientist, however; not only does he dabble in experimental and often dangerous technology (such as teleportation and patchwork rockets), he also keeps a defanged, flesh-eating alien parasite for a pet.
* ''VideoGame/WarioWare'' has Penny Crygor, Mad Scientist's Beautiful ''Grand''daughter. Of course, she's just as crazy and intelligent as her grandfather, and given the [[{{Jerkass}} males]] [[FunnyAfro of]] [[InterspeciesRomance the]] [[{{Nerd}} series]], is probably grateful for the lack of romance.
* [[spoiler:Marta]] in ''VideoGame/TalesOfSymphoniaDawnOfTheNewWorld''.
* Nina Cortex from ''VideoGame/CrashOfTheTitans'', the young niece of longtime series BigBad, Dr. Neo Cortex. More of a subversion, if anything; She's not exactly 'beautiful', and the reason for betraying Cortex was because she felt he wasn't being evil ENOUGH, and becomes the game's Big Bad. She's still a villain, if somewhat more minor, in her other appearances.
* Keira from ''Franchise/JakAndDaxter'' is the daughter of a mad green eco sage who serves as the [[FirstGirlWins main love interest]], and serves as the resident WrenchWench.
* In ''VideoGame/{{Overlord}}'', [[spoiler:either mistress you run into in the game turns out to be a daughter of the BigBad (or rather, they are daughters of the wizard who became possessed by the BigBad)]].
* In ''VideoGame/TraumaTeam'', we have [[spoiler: Rosalia Rossellini, Professor Sartre's adopted daughter]].
* ''[[VideoGame/{{Twinbee}} Pop'n Twin Bee]]'' has Dr. Murdock and Madoka.
* ''VideoGame/ChronoTrigger'':
** Schala is a {{Magitek}} version of this. Her mother, [[GodSaveUsFromTheQueen Queen Zeal]], ordered the creation of the [[DoomsdayDevice Mammon Machine]] and [[OminousFloatingCastle Black Omen]] which exploits the power of [[EldritchAbomination Lavos]] which in turn is eating the planet from its core. She succeeds, and become an immortal [[MoralEventHorizon at the cost of Schala and Janus.]]
** Lucca and her dad are a {{Subversion}} in that both of them are fairly mad (10th century time machine!), but are otherwise decent people and are on your side.
* Scarlet Nova is the daughter of the evil emperor of Gravora in the B-Movie inspired game ''VideoGame/TheDeadlyTowerOfMonsters.''
* ''VideoGame/ChronoCross'': [[spoiler:Kid is Schala's clone/reincarnation/[[MindScrew something like that]].]]
* From ''VideoGame/PokemonBlackAndWhite'': [[spoiler:N. Let's see: Mad dictator for father? Check. Only son? Check. (If they are related at all...) Beautiful? [[{{Bishonen}} I think we can let the fangirls field this one.]] Innocent? His views about the relations between Pokemon and Humans are certainly naive. Late teens? Check. Loves his father dearly? Unfortunately. Kept cloistered from the rest of the world? Oh yeah, to the point where much of Ghetsis' plan revolved around the way this would warp his views! Sometimes has doubts about his methods? He certainly starts to question himself after hearing the PC's Pokemon talk. Falls in love with the hero/heroine? Well...something like that, anyway. At the very least, he comes to see the PC as a friend. Betrays his father? Not until said father has already revealed himself as a monster, so that's a no, but otherwise, N has this trope ''covered''.]]
* Lady in ''VideoGame/DevilMayCry3DantesAwakening'' is [[spoiler:eventually revealed to be the daughter of Arkham. She chose to use the name Lady to distance herself from him]].
* In ''VideoGame/TacticsOgre'', we have Mad Necromancer Nybeth, who loves experimenting with the dead. He has ''three'' beautiful daughters, two of which rebel against him.
* ''VideoGame/ResidentEvil6'': Sherry Birkin, in addition to ShesAllGrownUp.
* ''VideoGame/{{Borderlands 2}}'' has [[spoiler:Angel, the daughter of Handsome Jack who communicates to the player through their ECHO devices initially as part of Jack's scheme to take down Sanctuary but later to help the heroes take down her father (who keeps her around as more or less a supercomputer due to her Siren powers)]].
* Oblio of video game Dance Central, is the son of the evil mad scientist Dr.Tan, but unlike his father, is beautiful.
* In ''VideoGame/MadFather'', Aya is one to Dr. Drevis.[[spoiler:Of course, this makes her father more eager to make her into a doll, and she becomes a MadScientist like her father in the true ending.]]
* ''Franchise/MortalKombat'' has plenty of this:
** Shang Tsung's creations include Mileena (who starts as a {{Stripperific}} ButterFace and later switches to CuteMonsterGirl), Ermac ([[IAmLegion Whom are a collection of souls bound into a red ninja]]) and Skarlet (who is similar to Ermac, but with [[InterplayOfSexAndViolence blood instead of souls]]) While both Mileena and Skarlet are achingly beautiful (for the most part), Shang Tsung himself bounces between playing straight and subverting this trope as well.
** Quan Chi plays this somewhat straight in ''[[VideoGame/MortalKombatX X]]'', where the Revenants that he makes are of the [[spoiler:dead fighters from ''VideoGame/MortalKombat9,]] all of which are better looking than he is.
* In the third installment of the ''VideoGame/DrBrain'' series, "The Lost Mind of Dr. Brain", we are introduced to his assistant, his niece, Elaina, who provides the player with instructions on each mission, as well as hints, if the need arises.

[[folder:Visual Novels]]
* ''VisualNovel/AceAttorney'':
** Change "scientist" to prosecutor, and "daughter" to "adopted son", and you get Miles Edgeworth, especially if you take into consideration the strong emotional bond (platonic [[FoeYay or]] [[HoYay otherwise]]) between him and Phoenix.
** Franziska von Karma, Manfred von Karma's ''actual'' daughter and while she holds to her father's perfectionist ways she's actually got some moral fiber to her. [[spoiler:In the third game she becomes an indispensable ally. Edgeworth needs to be a defense lawyer in Wright's place, but apparently he can't technically do that. After they make sure they get a judge who doesn't know Edgeworth, Franziska comes in to serve as prosecutor because she's the only one who won't rat him out.]]
** In ''VisualNovel/ApolloJustice'', take the MadArtist's pretty daughter, Vera Misham.

[[folder:Web Comics]]
* The superhero Falchion from ''Webcomic/DoesNotPlayWellWithOthers'' is dating the daughter of his arch-nemesis. [[spoiler:Actually, she ''is'' his arch-nemesis, who wears a suit of PoweredArmor with a voice changer to make her look and sound male, and she {{exploited| Trope}} this trope for all it's worth to save her own ass when Falchion showed up at her evil lair unannounced while she wasn't wearing the suit. [[AllWomenAreLustful The fact that it also helped her get into his pants was a bonus]].]]
* ''Webcomic/GirlGenius'': Given the backstory, "{{Mad Scientist}}s rule the world. Badly", it's not surprising that there are a lot of these, played straight, inverted, bent, folded, spindled, or otherwise mutilated:
** BackStory-only: Lucrezia Mongfish, daughter of evil MadScientist Lucifer Mongfish, and a MadScientist herself. She denounces her father's evil and marries TheHero MadScientist Bill Heterodyne. Since Bill, his brother Barry, and all of their TrueCompanions are immortalized in the "[[FamedInStory Heterodyne stories]]," she is regarded as a [[TropeCodifier Codifier for this trope]] in universe[[note]](Especially the part where the audience likes her more before the obligatory HighHeelFaceTurn.)[[/note]]. [[spoiler:She turns out to be more evil than her father, and is in fact the BigBad. [[EpilepticTrees Maybe]]]]. Her two sisters qualify for this as well. maybe.
** Agatha Heterodyne, Bill and Lucrezia's daughter, the protagonist. Also a MadScientist. Agatha's not really innocent, though, being trained as a spark herself. And both her birth and her real parents were firmly good-aligned, so she's not really rebelling. So she's more of a deconstruction of the trope.
** Gilgamesh Wulfenbach, Handsome Son of the MadScientist and AntiVillain (not-so) EvilOverlord Klaus Wulfenbach. Also (say it with me) a MadScientist.
** Tarvek Sturmvoraus, Handsome Son of [[spoiler:the current (now deceased)leader of a not-so-AncientConspiracy]]. Potential love interest and also (you knew this was coming) a MadScientist. He has a sister, who decidedly does not fit the trope.
** The whole thing gets sent up by Othar Tryggvassen, GentlemanAdventurer (and, of course, MadScientist): he meets Agatha while imprisoned aboard Klaus's flying airship castle, and assumes she must be his captor's previously-unknown beautiful daughter, there to either taunt him or set him free.
** Zola, [[spoiler: Lucrezia's niece,]] is at least a mad scientist's beautiful granddaughter. Though unlike just about every other example in this work she doesn't show any sign of having inherited [[ScienceRelatedMemeticDisorder the Spark]].
** If WordOfGod is to be trusted about Zeetha [[spoiler:being Baron Wulfenbach's daughter and Gil's twin]], then she is an ActionGirl but, like Zola, is not actually a MadScientist herself.
** Colette, daughter of the Master of Paris, is so far the straightest yet iteration of this trope, being the beautiful daughter of a (take a shot) MadScientist, who helps out the heroes - but ''not'' in defiance of her father, because the Master of Paris is on the good guys' side, [[GoodIsNotNice just rather stern.]] [[spoiler: Colette ends up ascending to the role of Master of Paris upon her father's death, while finally breaking through to become a Mad Scientist in her own right.]]
* Michelle Flammel from ''Webcomic/{{Monsterful}}'', her father Lionel Flammel is a handsome MadScientist/alchemist/magician known for his mad creations. Michelle loves her father dearly but she also thinks that he can be very stupid at times.
* This is expanded in the ongoing ''Narbonic'' fanstory ''FanFic/TheMadScientistWars'', where Jane Narbon is the (incredibly beautiful) daughter of Helen Beta and Dave. In addition to being TheVamp, she's also (yup) [[MadScientist Mad]].
* Helen Beta Narbon, the main character of ''Webcomic/{{Narbonic}}'', who is actually a clone of her mother (and comes from a long line of clones) and a mad scientist herself.
* Hannelore from ''Webcomic/QuestionableContent''. [[MundaneFantastic Raised on a space station]] by a MadScientist and a CorruptCorporateExecutive. She rebels, but doesn't betray either of them. Also, she was less "cloistered away" and more "neurotic to the point she wouldn't talk to anyone except the station's AI".
* ''WebComic/{{Shortpacked}}'':
** Her name is Conquest (Connie for short), and the phrase AnythingThatMoves hardly does her justice. She is known for giving out sex "free with purchase", any purchase, at her father Galasso's toy store. Nevertheless, he seems to be under the impression that she is a virgin, even though he has continually forced her to copulate with anyone he considers capable of producing a (male) heir for him. There's even mention of a time he witnessed a heroic horse, and tried to [[{{Squick}} use her to breed centaurs]]. Despite having a head full of air and a libido that's UpToEleven, she is surprisingly canny and eventually rebelled against her tyranical father, and is now apparently one of his main business rivals. She's still a tramp, though, and considers a tryst with one of Galasso's more attractive male employees a suitable substitute for a briefcase full of cash as a bribe.
** She's also a direct parody of [[Franchise/{{Batman}} Talia al Ghul]] (see above). Galasso decided to name Ethan his successor, and gave him Conquest as part of the deal. He went for it at the time, but later discovered that he is gay and refused to go through with it any more. Galasso didn't even seem to understand the concept, and then ordered Robin to impregnate Connie instead. For the record, Robin is a girl. Yeah, the jury's still out on how someone like Galasso managed to acquire a daughter to begin with.
* Oasis was one of these to Dr. Steve during her first appearance in ''Webcomic/SluggyFreelance''. Interestingly, Steve actually uses his mind control device to ''make'' Oasis fall in love with Torg, much to Torg's [[{{Yandere}} displeasure]].
* Tabitha in ''Webcomic/FarOutThere'' is not only a [[http://faroutthere.smackjeeves.com/comics/1794321/page-566-just-keep-doing-what-youre-doing looker]], but followed her Daddy's footsteps into being a MadScientist herself.

[[folder:Web Original]]
* Jadis Diabolik of the ''Literature/WhateleyUniverse'', in her first (chronological) appearance, even [[LampshadeHanging references this trope]]. It's one of her [[BerserkButton hot buttons]] that she's the daughter of the [[WellIntentionedExtremist infamous mass murderer]] [[MadScientist Dr. Diabolik]], and she has the Exemplar superpower, but she's isn't actually beautiful - she's plain, and elsewhere would be considered moderately attractive, but compared to all the other Exemplars running around, she feels incredibly ugly (plus, it hasn't been stated for certain that she is an Exemplar or if something her father did just mimics the effects). She is [[ACupAngst particularly sensitive]] about not having the MostCommonSuperpower, which is almost universal in female Exemplars (at lest those who don't get a BodyHorror result instead). Despite this, she did have a guy vying for her attention after she saved him from a smalltime super villain thug, and two others at Whateley (though one's a creep who imagines himself to a ComicBook/{{Batman}}-esque ByronicHero, and the other just wants favours from her father and the parents of the other Bad Seeds).
* ''Website/GaiaOnline'''s Gino Gambino might be a [[DudeLooksLikeALady dude]], but he otherwise fits this trope.
* Doctor Gladiola Thanos, a DiabolicalMastermind from the ''Roleplay/GlobalGuardiansPBEMUniverse'' is the daughter of MadScientist Doctor Thaddeus Thanos. Her father was active in the 1980s and regularly fought the heroic Captain Challenger until he was killed during a lab explosion that resulted from a fight between the hero and Doctor Thanos's minions. While she originally followed this trope by helping the hero fight against her father's diabolical plots, his death sent her into a HeroicBSOD that ended with her following in his footsteps as a supervillain. Her first act of villainy was to find and kill Captain Challenger and his entire family.
* An unofficial ''TabletopGame/{{Champions}}'' character named [[http://www.rogermwilcox.com/champions/scientist.html The Scientist]] has a young, beautiful, virgin daughter. And he always calls her that, much to her chagrin, until her kidnappers (the evil [[http://www.rogermwilcox.com/champions/macron.html M.A.C.R.O.N.]]) return her and say "Here you are, your young, beautiful ... daughter." ("It was my idea, daddy. Have you ''seen'' what this hunk looks like under his armor?!")
* ''WebAnimation/DrHavocsDiary'': We have Ally Havoc, the daughter of the titular Dr. Darren Havoc.

[[folder:Western Animation]]
* Though a departure from her portrayal in the comics, Lorna Dane a.k.a. Polaris is made into something of a Mad Scientist's beautiful daughter in ''WesternAnimation/WolverineAndTheXMen''. She, unlike her siblings, is intentionally kept innocent and naive of the reality of the society her father (Magneto) created on Genosha. And in one episode she falls for Gambit who, ''[[AntiHero while his status as a hero may be suspect]]'', is the enemy of her father (in that ''[[GentlemanThief he plans to steal from him]]''.)
* Aelita from ''WesternAnimation/CodeLyoko'', though her father's sanity is more questionable than definitely not present.
* Bonnie Lepton in the ''WesternAnimation/BuzzLightyearOfStarCommand'' episode "Eye of the Tempest", the [[SheIsAllGrownUp All Grown Up]] daughter of a former Star Command scientist who became [[WithGreatPowerComesGreatInsanity mad after experimenting on himself]].
* ''WesternAnimation/JimmyNeutron'''s nemesis, Professor Calamitous, has a daughter who's actually named "Beautiful Gorgeous". Contrary to the trope, she's possibly more evil than her father, and almost certainly more effective at it.
* ''WesternAnimation/MyLifeAsATeenageRobot'':
** Melody is a mad scientist's beautiful ''robot'' "daughter"... unbeknownst to her love interest Brad as he struggles to escape from her father's captivity.
** Jenny herself, though it was her ''mother'' who made her. At first, she was only allowed out to save the world.
* ''WesternAnimation/PhineasAndFerb'':
** Vanessa Doofenshmirtz (pictured) plays with this trope in different ways. In early episodes she was outright disdainful towards her father and his experiments, generally playing the role of DeadpanSnarker. She [[CharacterDevelopment warmed up to him in later episodes]], though she remains somewhat annoyed by his exploits and his attempts to make her into a DaddysLittleVillain (though some of her actions hint she may head down that path anyway). She's also notably uncloistered (she only spends [[VisitByDivorcedDad alternate weekends]] with her father anyway) and keeps her relationship with [[AnimalSuperhero his]] [[EverythingsBetterWithPlatypi nemesis]] friendly but strictly platonic.
** {{Played Straight}}er in recent episodes, when she has developed an interest in Major Monogram's son, (human) secret agent Monty Monogram. However, their first date actually devolved into a fight when Monty made a comment about her father, so the betrayal part probably isn't going to happen.
* Kitten from ''WesternAnimation/TeenTitans'' may [[AmbiguouslyHuman not even truly have been human]], seeing as her father was Killer Moth, and her [[DaddysLittleVillain beauty was clearly only skin deep]] but given the nature of Killer Moth's scheme's she technically qualifies.
* Subverted in the short-lived Creator/{{MTV}} cartoon ''WesternAnimation/SpyGroove'' with Sierra Nevada, the daughter of a mad robotics genius/casino owner. Turned out ''she'' was the mad genius; daddy was just a robot she built to draw attention away from her while she played this trope to the hilt to fool do-gooders.
* In ''[[Literature/InterviewingLeather Interviewing Trey]]'', the beautiful (to the point of actual paranormal charisma) Beguile is the daughter of the mad scientist Doctor Guile.
* The second season of ''WesternAnimation/JonnyQuestTheRealAdventures'' not only brought back the Quests' arch-nemesis Dr. Zin, it also gave him two daughters, Anaya and Melana, one whom becomes romantically involved with Hadji.
* Though not necessarily a bad guy, Dr. Orpheus from ''WesternAnimation/TheVentureBrothers'' is a mad scientist/necromancer with a relatively normal teenage daughter, Triana, whom he loves and cares for, humorously mixing his medieval, renaissance faire-like attitude with the trials of a modern-day single dad.
* In ''WesternAnimation/DannyPhantom'', Jazz defiantly takes after her mother. Even when she won't admit it ''and'' when Jack Fenton is more bumbling than mad.
* In ''WesternAnimation/TheLegendOfKorra'' [[spoiler:Asami Sato is a case where she didn't ''know'' she was the daughter of a mad scientist who hid behind the image of a successful business owner that secretly supplies weapons and MiniMecha to the [[MugglePower Equalists]]. Even if her father had a strong FreudianExcuse for doing so, she is not happy to discover this]].
** And [[spoiler: the leader of the Equalists, Amon/Noatak, was the TallDarkAndHandsome son of would-be mad dictador Yakone. Same goes to his younger brother, Tarrlok.]]
* Farmer Brown from the ''WesternAnimation/BatmanTheAnimatedSeries'' episode "Critters" can count as a Mad Scientist, seeing as he was using microbiology to create monstrous farm animals. And he did indeed have a beautiful daughter named Emmylou. She was also his enforcer, and was ''much'' stronger than her almost petite frame would appear, being more than a match for Batgirl. (She claimed it was due to beef steroids, clearly another of her dad's experiments.)
* In ''WesternAnimation/SkysurferStrikeForce'', Cerina is the daughter to show BigBad, Cybron. Unlike most of the examples though, she's clearly evil.
* Julie Kane in ''{{WesternAnimation/Motorcity}}.'' Abraham Kane's technically not a mad scientist, but she still fits the trope. She also kept it a secret, fearing her friends will think she's just like him.
* Dr. Vahtoss and his daughter Carmalita from ''WesternAnimation/TheTick''.
* The ''WesternAnimation/{{Ben 10}}'' series invokes this with Attea, daughter of Emperor Milleous. Her father has her carefully watched, but she [[spoiler:manages to betray him, fall for the hero (when he's the same species), and take over daddy's empire]] over the course of a [[TwoPartEpisode two-parter]].
* In ''WesternAnimation/RickAndMorty'', Beth (the daughter of Rick and mother of Morty) is older than the typical example, but still qualifies. Much like Rick, she's smart, selfish, and an alcoholic, albeit to a lesser extent. She slips into the typical DaddysGirl, often giving Rick the benefit of the doubt and putting him ahead of other family members, but isn't above calling him out when his antics are particularly egregious.

[[folder:Real Life]]
* Catherine Barton was the ''niece'' of UsefulNotes/IsaacNewton (he never married and had no children), but she did live in his house in London. She was renowned for her beauty and wit. Newton himself was an Alchemist and heavily into the occult and weird.