These characters typically weren't born immortal, but they didn't let that stop them. They find or create an object, magical or scientific, that will grant them that which they seek.

This trope happens whenever a character is immortal through the agency of a physical object. How the object works can be very varied. It may be PoweredByAForsakenChild, thus invoking ImmortalityImmorality, or it could be powered by harmless TechnoBabble.

The extent to which it works and what kind of {{immortality}} it bestows also varies. It might only work on a single character, or it could work on anyone in the vicinity. It may also have negative side effects, especially if it's a prototype or created by a MadScientist. Said object will often be an AmuletOfDependency: they will typically lose that immortality if the object is destroyed or sometimes just if they lose contact with the object, often resulting in NoImmortalInertia.

In some cases, characters may try to merge with this item in order to gain its effects permanently. This may work, or it might backfire horribly, depending on the story and what the object is.

There are typically three forms this trope can take: the object simply existing grants them immortality, the object must be used in some way periodically to keep them immortal, or the object must be worn or carried in order to make them immortal.

Likely to be a MacGuffin or PlotCoupon. If the Immortality Inducer can be mass-produced, it may lead to a SocietyOfImmortals.

Supertrope to SoulJar and HeartDrive. Subtrope of {{Immortality}}.

Contrast ArtifactOfDeath.


[[folder:Anime and Manga]]
* ''Manga/{{Bleach}}'': the Hogyoku was originally created to eliminate the barrier between shinigami and hollow. Later, it is revealed to grant the heart's truest desires; assuming the Hogyoku is exposed to twice captain level reiatsu, and that one has the inherent potential to fulfill their wish. And then...? [[spoiler: Aizen merged with it and was somehow granted immortality. So... either he was immortal to begin with, or had the potential to become...?]]
* In OnePiece, some devil fruits give their user immunity to some lethal attacks. To gain such immortality, a person has to eat a devilfruit.
** Logias are immune to everything except their natural weaknesses, devilfruit weaknesses or haki users.
** Buggy is immune to slashes. Even Mihawk, the 'greatest swordsman in the world', couldn't kill Buggy with his sword.
** Brook's power is the closest to immortality of any of the fruits. After dying, his ghost was able to reanimate his skeleton body. With a lack of organs, most attacks cannot kill Brook, though he can still suffer pain and be defeated in battle. Brook can also turn into a ghost by escaping his body.
* The Grand Panacea from ''LightNovel/{{Baccano}}'' has this effect; anyone who drinks it ceases aging and [[GoodThingYouCanHeal almost immediately]] recovers from any injury (seriously, if they're burned the ash turns right back into flesh). The only way to "kill" an immortal is for another to [[IdentityAbsorption absorb]] them (which gives them their memories in the process). There's also lesser versions of it that grant invulnerability and the weakness to being absorbed but not immunity to aging.
** According to the novels, Baccano immortals are actually immune to fire and acid, not just able to recover from it. Szilard's research has shown that their individual cells are completely indestructible and anything that involved breaking down things on a cellular level such as burning (or acid), won't actually do anything to them. The damage that fire/acid does to the outer portion of their cells is so small it regenerates instantly resulting in immortals that don't give off smoke while on fire since their cells don't even have time to turn into ash, and fires that will burn literally forever as long as they have enough heat/oxygen to keep the reaction going since the immortal's body provides unlimited fuel. That's not to say it doesn't hurt them, since their nerves can still sense the heat and register it as pain.
* In ''ZombiePowder'', various "powder hunters" search for the Rings of the Dead, which when brought together produce a substance called Zombie Powder that can be used to either raise the dead or grant immortality to the living.
* Rin and Mimi in ''{{Mnemosyne}}'' became immortal when "time spores" entered their bodies. They can sustain severe injuries and regenerate themselves fully, as is shown with the often [[{{Gorn}} gruesome stuff]] that is inflicted on Rin. There is one character in the show who actually eats time spores, preferably old ones, so Rin and Mimi still have to watch their step.
* The Philosopher's Stones in ''Manga/FullmetalAlchemist''. Every character laying claim to immortality possesses at least one, allowing them to regenerate from injuries (including fatal ones); however, this expends their Philosopher's Stones, meaning that a [[{{Badass}} sufficiently]] [[{{Determinator}} tenacious]] opponent can still kill them. It's also possible to destroy their Philosopher's Stones directly through alchemy, or even rip them out [[spoiler:as Envy [[DrivenToSuicide does to himself]] [[TalkingTheMonsterToDeath after he's called on his hypocrisy]].]] Exactly how many "lives" a Philosopher's Stone grants is dependent on [[spoiler:how many human souls are contained within it]].
* In ''Manga/FairyTail'', during the Tenrou Island arc, both sides possess one.
* ''SamuraiSeven'' has a ruler enthroned in a machine that prolongs his life.
* Both Yukiko and Liselotte Werckmeister from ''VisualNovel/ElevenEyes'' share the same immortality that comes with an rapid HealingFactor and [[TheAgeless the inability to age]]. It is revealed that the Voidstone is the source of the immortality and separating it from the host will disable that immortality.
* In L. Jagi Lamplighter's ''ProsperosDaughter'' trilogy, Prospero and his children are immortal between the effects of Miranda's Water of Life, and Eramus's staff's ability to cure.
* In ''Manga/JojosBizarreAdventure'', the Stone Mask created by the Pillarman Kars can grant immortality in the form of vampirism to humans. When combined with the Red Stone of Aja, the Mask can bestow CompleteImmortality.

[[folder:Comic Books]]
* One anthology issue of ''Comicbook/TheTombOfDracula'' featured a underground pool of blood that made any mortal contacting it immortal.
* ''SupermanAndBatmanGenerations'': There is a pool that makes a person submerged in it immortal, but two people have to enter together and one of them will die.
* The Lazarus Pits used by Franchise/{{Batman}} archfoe Ra's Al Ghul and others can rejuvenate the dying. Ra's Al Ghul is hundreds of years old thanks to the Pits.
* MarvelComics' [[ Ulysses Bloodstone]] is immortal because of a meteorite/gem shard stuck in his chest. At the end of his story, it gets surgically removed by some bad guys and he dies.
* The Sphinx, an enemy of Comicbook/{{Nova}}, was an Ancient Egyptian Priest given immortality and great powers by a gem he found in a mysterious temple. But he came to [[WhoWantsToLiveForever regret living for thousands of years]]; his main motivation was to find a way to end his own existence.
* VandalSavage was a Cro-Magnon man named Vadar Adg who found a strange meteorite that fell to Earth one cold night. He fell asleep near it, being bathed in its rays during the night, and he woke up an immortal being. However, the meteorite's effects aren't permanent; Vandal occasionally needs to eat the flesh and organs of his own descendants to maintain his immortality. (That bit is NewerThanTheyThink, added after the appearance of the immortal character with the same weakness in ''{{Smallville}}''.)
* NickFury stopped aging thanks to the Infinity Formula. His ArchEnemy Baron Strucker is also immortal thanks to the Death Spore and other serums HYDRA used on him.
* Mammoth Mogul from ''ComicBook/ArchieComicsSonicTheHedgehog'' is immortal thanks to the Chaos Emerald embedded in his chest.

[[folder:Film -- Animated]]
* In ''Disney/{{Tangled}}'', the magic flower and later Rapunzel's hair serve this role for Mother Gothel. Singing the magic song restores her youth.

[[folder:Film -- Live-Action]]
* ''Film/TheLeagueOfExtraordinaryGentlemen''. Dorian Gray's portrait, as in the original novel ''Literature/ThePictureOfDorianGray''.
* In ''IndianaJonesAndTheLastCrusade'', [[spoiler:the knight]] remains alive (but frail) by drinking from the Holy Grail.

* ''Literature/{{Animorphs}}'': During one of their several TimeTravel adventures, the team sans Jake are given this as part of two godlike characters' game. [[spoiler: The Ellimist exploited the ExactWords of the deal Crayak made to send the gang through time to chase Visser Four. Crayak demanded one life as payment, so he ''only'' got one: once Jake was killed, the others become Jack Harkness-esque immortal, instantly reverting to normal after damage no matter how [[ChunkySalsaRule chunky salsa-ified]] they get.]]
* ''Literature/ThePictureOfDorianGray'': the caveat is that the immortality wears off if the titular picture is destroyed.
* In ''Literature/HarryPotterAndThePhilosophersStone'', the title object turns out to be one of these, as you might expect. It produces the Elixir of Life, which makes the drinker temporarily immortal.
** In the last book, ''Literature/HarryPotterAndTheDeathlyHallows'', it's also believed that reuniting all three of the titular objects will grant immortality -- becoming the "Master of Death." [[spoiler:It turns out to be a subversion, wherein the true "Master of Death" realizes that death is inevitable in spite of the existence of magic, and that, in the end, there are far worse fates than dying.]]
* In ''Literature/{{Gor}}'', humans have immortality thanks to "stabilization serums" - shots - developed by the Caste of Physicians; basically, it's an immunization against old age. In one book, a woman from Earth actually gets de-aged from her 60s to age 18 or so thanks to the serum. The priest-kings, alien gods of the planet, have even more advanced stabilization serums which make them immortal until they decide to die, although they can be killed.
* "Anti-gerosome" in Creator/KurtVonnegut's short story "Tomorrow And Tomorrow And Tomorrow" is a cheaply produced serum that stops ageing. This makes the world horribly over-populated, and static - one family's great-great-grandfather is still holding sway over all the descendants crammed into his home.
* The Font of Immortality (the drink, not the typing) is one of the five artifacts in ''Literature/{{Fablehaven}}''. The catch is that it must be drank from at least once a week (don't worry, it's infinite), or else the drinker will spontaneously [[NoBodyLeftBehind turn to dust]].
* [[EvilOverlord The Lord Ruler's]] bracers in ''{{Mistborn}}'', which work due to the fact that [[spoiler: he's a master of two metal-based magic systems which have odd interactions between them]]. They're made of [[{{Unobtainium}} atium]] which [[spoiler: the Lord Ruler can use to store youth for later consumption using Feruchemy- with the side effect that he has to become old for an equivalent amount of time that he's young, because Feruchemy is an EquivalentExchange system]]. Add his ''other'' magic system, Allomancy, which lets him draw power from the metal itself- [[spoiler: by "burning" the bracers he's charged with Feruchemy, he's got a pair of magical objects that make him- and only him- infinitely young]]. This neat trick is called "compounding", and was the source of his [[PhysicalGod godlike general abilities]], though only the bracers are this trope.
* In Megan Whalen Turner's ''[[TheQueensThief The Thief]]'', Gen ([[ExactlyWhatItSaysOnTheTin the titular character]]) is recruited to help find a stone that grants immortality to whoever is wearing it. [[spoiler:After he steals it, he hides it in his hair and attempts to escape, but is caught up in a fight and stabbed in the chest. When the sword is removed Gen describes it as feeling as though his life is being stretched thin by the blade, and it causes him an immense amount of pain. Gen decides the pain isn't worth it and swears off ever wanting to be immortal again.]]
* [[spoiler:Durzo Blint, and later Azoth/Kylar Stern gain immortality after bonding with the Black Ka'kari]] from ''Literature/TheNightAngelTrilogy'' by Brent Weeks.
* Wowbagger the Infinitely Prolonged from ''Literature/LifeTheUniverseAndEverything'' gained immortality during an incident with a particle accelerator, rubber bands, and a liquid lunch. [[spoiler:In ''Literature/AndAnotherThing'', his immortality is revoked when those same rubber bands wrap around Thor's hammer.]]
* The Denarians in ''Literature/TheDresdenFiles'' are immortal due to the presence of the {{Fallen| Angel}} contained in the silver denarius coin each one carries. Furthermore, Nicodemus is given extra protection by the fact that he wears the noose Judas Iscariot supposedly used to commit suicide around his neck, which allows him to regenerate damage that would drop even other Denarians who are protected by their respective Fallen.
* In JohnCWright's ''[[Literature/TheGoldenOecumene Golden Age]]'' trilogy, nomenual recordings allow effective immortality. Although it is a major plot point that the heat death of the universe will ensure that this is not actually living ''forever'' -- the most that is possible is until every form of energy in the universe is completely consumed.
* In Creator/RobertEHoward's ''ConanTheBarbarian'' story "Literature/TheTowerOfTheElephant", Yara is said to be centuries old, and immortal because of his [[MineralMacGuffin gem]], the Heart of the Elephant.
* In ''Literature/LordOfTheRings'', this is one of the things the One Ring can do. Gollum's unnatural age is thanks to it. The Nine for the Nazgūl also serve this function. It's not a pleasant experience however, as it makes you feel "sort of stretched, like... butter scraped over too much bread."
* In ''TheHistoryOfTheRunestaff'', King-Emperor Huon's life is indefinitely prolonged by the Throne Globe, an elaborate piece of LostTechnology. From the outside, it looks like a glass sphere full of translucent fluid in which Huon floats. He can talk to people in the room, but he can't leave the sphere or move it. If it were to be destroyed, which would not be terribly hard considering it's made of glass, he would die.
* The narrator in Xanadu by ''{{Rush}}'' gains immortality after entering the Pleasure Dome, dining on the honeydew, and drinking the milk of paradise. He is ''not'' happy about it.
* In ''{{Dragonlance}}'', [[EvilSorcerer Fistandantilus's]] bloodstone pendant allowed him to drain the life-force from other wizards to prolong his own existence. [[spoiler: Unfortunely for him, his BastardUnderstudy Raistlin figured out that he would be the next victim and turned the tables, stealing the bloodstone and using it on Fistandantilus himself, killing him, absorbing his memories and life-force, and stealing his identity to boot]].
** Berem, the "Everman", has a green stone embedded in his chest granting immortality. He tried to steal it from the Foundation Stone.
* In the Old Norse ''Literature/TaleOfNornaGest'', the magic of a norn makes Norna-Gest immortal so long as a certain candle is not destroyed.
* In Creator/UrsulaKLeGuin's ''Literature/ChangingPlanes'', one world that the narrator visits has an island which has a small population of immortals, whose eternal life is believed to be granted by the mosquitoes that are endemic there. Unfortunately, this is Type VI immortality, with a normal human ability to heal. The immortal that she is fortunate enough to meet is a withered husk after having survived falling into a lava stream. The natives don't seem to worry about this fate because, according to them, [[spoiler:there is just one]].
* Cell activators in ''Literature/PerryRhodan'' are the AmuletOfDependency type in that once one has been worn for too long, the wearer will die from accelerated cellular decay after about 62 hours if they ever lose it. The benefits do, however, include lack of aging, a modest HealingFactor, and virtual immunity to all but the fastest-acting of poisons. The "classic" version was a literal amulet (a small egg-shaped pendant traditionally worn on a chain), which had the obvious drawbacks but also the advantage that it could be temporarily loaned to other characters to let them take advantage of its healing properties; the "modern" one is an implanted chip, which is rather harder to lose (without resorting to surgery, which some prospective thieves ''have'' tried) but also can no longer be used to help others in that fashion.
** Before the activators, there was the "cell shower" -- a fairly brief and painless treatment that would stop the aging process (only) for 62 years, with chronological age presumably catching up soon afterwards if not repeated. The catch in ''this'' case was that this treatment was available only on the planet of the SufficientlyAdvancedAlien who provided it to sufficiently worthy individuals, and that planet could at times prove rather elusive and was in any case eventually destroyed. (It's since been replaced at least once, but IT -- the alien in question -- now seems to feel that the activators are sufficient by themselves.)
* In the StarWarsExpandedUniverse, there is a whole planet, Iego, that works as this. Anyone living on this planet doesn't age and doesn't need nutrition as long as they don't leave. If they leave, no ill effects happen, the biological processes just resume. Of course, the catch is that Iego is a DeathWorld by itself, and grants no immunity to violent death.
* In ''{{Nightside}}'' a street vendor is selling immortality serum. The real deal. "One sip, and you'll live forever. [[note]]You'll be a frog, but you'll live forever.[[/note]]"
* Ritual from {{Repairman Jack}} novel ''The Haunted Air''. [[PoweredByAForsakenChild A living child heart has to be eaten between summer solstice and the autumnal equinox every year.]] After 29 times user stops aging and becomes immune to harm and diseases for as long as ritual is kept up. [[NoImmortalInertia Else...]]
** Also, the necklaces worn by Kolabati and Kusum in ''The Tomb'' could grant a person [[TheAgeless agelessness]] if worn for an extended period of time. Problem is, they'll become [[AmuletOfDependency Amulets of Dependency]] after a while and their wearers will rapidly age if separated from them.
* ''Literature/GloryInTheThunder'': When an Aspect of the Divinity decides it has finally found the right person, it will resurrect them as an immortal when they die. They usually make [[GodIsEvil rather poor choices]].
* The CR (Cellular Regeneration) treatment in ''Literature/CaptainFrenchOrTheQuestForParadise'' has turned humanity into TheAgeless. Overpopulation is managed both by PopulationControl (in the form of child licenses and easily-available and reversible sterility) and settling new worlds. People still die from violence or accidents, although WeWillHavePerfectHealthInTheFuture is also in effect. The titular character is biologically over 2000 years old, although he was born 20,000 years ago (thank TimeDilation), and was one of the first to receive the treatment (albeit quite late in life; most people do it in their 20s, while he did it in his 50s and shocks people with his grey hair).
* In Aleksandr Zarevin's ''Lonely Gods of the Universe'', the titular "gods" are HumanAliens who have arrived to Earth thousands of years ago to escape the BigBad. One of the first things they did was plant an herb from their homeworld called ambrosia. Surprisingly, the herb grows into a plant overnight. They make a meal with ambrosia and eat it. Suddenly, they all feel excrutiating pain and faint. Some time later, they wake up, feeling better than ever. The old professor in their group has somehow become a young man again. They find out that they have become TheAgeless and have a limited HealingFactor. Unfortunately, ambrosia withers in a matter of days, although they manage to dry some of it and store it for the future (the main character ends up taking some to regrow his legs lost during a PortalCut and become immortal). The characters become the rulers/gods to the primitive humans who live on their island, turning them into a powerful civilization with a navy that establishes colonies all over the Mediterranean. They name their island Atl-antis after their home country and the hill where their palace is built Oll-ympus after their homeworld. A security guard sent with them becomes the commander of the island's armed forces. His name? Mars Ares. The island is later sunk by a comet strike.
* Immortality in ''Literature/ClocksThatDontTick'' was reverse-engineered from a girl whose unique mutation prevented her from growing. After throwing in super white blood cells to stave off disease, it became marketable. But it doesn't come cheap.
* In the ''Literature/MediochreQSethSeries'', dragon's blood has healing and regenerative properties on living things. More than one villain has tried to exploit this in some way. Of particular note, in the first book, [[ArchEnemy Maelstrom]] managed to survive for centuries by regularly injecting himself with the stuff.
* The Large Hadron Collider at CERN is jury-rigged to become an Immortality Inducer in ''[[Literature/ZeusIsDead Zeus Is Dead: A Monstrously Inconvenient Adventure]]'' via some material from Saturn's rings, some "really good fudge," and a few extra tweaks of [[spoiler: Zeus's power]].

[[folder:Live-Action TV]]
* In ''Series/DoctorWho'', despite regaining a set of regenerations, the John Simm version of the Master forces himself not to, storing his essence inside a ring to revive himself later.
** Similarly, the Kastrian Eldrad was blown into a single hand. He and his entire race could store their genetic imprint into a ring to be reawakened with a burst of radiation even after over a hundred million years.
** Then there's the Time Vortex, which can do virtually anything. When Rose absorbs it, she uses it to revive the recently-killed Captain Jack Harkness. However, since she is an inexperienced "Time Goddess", she ends up reviving him ''permanently'' (essentially setting his "revive" setting to "always on"). Nothing can kill him (unless [[spoiler:a giant vagina in Earth makes him mortal again, overriding the Time Vortex]]).
* ''{{Space 1999}}'' episode "The Exiles". Two prisoners have extended lifespans due to skintight membranes covering their bodies. If the membrane is ripped and their bodies are exposed, they're subjected to RapidAging and die.
* Goa'uld sarcophagi in ''Series/StargateSG1'' are best described as {{Autodoc}}s, but they're so effective that they can ''raise the dead''. The System Lords are thousands of years old thanks to them. Shame about the [[AGodAmI side effects]].
** As evidenced by Lord Yu, even a sarcophagus can, eventually, prove useless, if a symbiote is extremely old. Yu is shown to be suffering from the Goa'uld version of senility, such as ordering fleets to a battle that was fought long ago. His [[NumberTwo First Prime]] complies, of course, but then conspires with Teal'c to turn command of the fleets over to [[MagnificentBastard Ba'al]]. Ba'al is, at first, outraged that a First Prime would betray his god, but relents after Teal'c suggests offering the deal to a rival System Lord.
* In ''Series/TorchwoodMiracleDay'', [[spoiler:the Blessing]] is this, coupled with [[spoiler:Jack's immortal blood]].

* In RagnarokOnline, the Soul Linker job change implies that your character owns several.
--> This Witherless Rose will wither away instead of you...\\
This Immortal Heart will cease to pump blood, instead of yours.\\
This Diamond will turn to dust in place of your mortal body.

* The Fountain of Youth.
* This was said to be one of the many effects of the Philosopher's Stone.
** The ultimate goal of Chinese alchemy, rather than the western "lead into gold," was to create an elixir that granted immortality.
** For some western alchemists, the point of turning lead into gold was also to create an elixir of immortality: the the thinking was that gold is the purest metal, and transmuting the base dross of lead into gold would mean turning common flesh into angelic perfection.
* In ChineseMythology, the Peaches of Immortality grow in the garden of the Jade Emperor of Heaven and are given to gods, sages and others deemed worthy of them.
* In JapaneseMythology, Ningyo or Mermaid flesh was said to give near infinite vitality unto the eater.
* In GreekMythology, the food of the gods, grows on Mt. Olympus and grants their immortality.
* In NorseMythology, the gods maintain their immortality by the eating of [[HowDoYouLikeThemApples golden apples]] cultivated by the goddess Išunn. You might be noticing a pattern here.

[[folder:Tabletop Games]]
* The CCG ''TabletopGame/{{Illuminati}}'' had the card [[ Immortality Serum]], which not only made the affected character indestructible, it could be played on an opponent's characters to make them defect!
* ''MagicTheGathering''
[[ The Fountain of Youth]] gives players a cheap method of increasing their life points. Only the pigeons ever discovered its secrets, since no one in their right mind would drink from a dirty public fountain (especially if pigeons bathe in it).
[[ Elixir of Immortality]] is, according to its FlavorText, literally bottled life, though somewhat stale and not particularly palatable.
* ''TabletopGame/CallOfCthulhu''
** ''Cthulhu Companion'' adventure "The Secret of Castronegro". Bernardo Diaz has lived for 300 years due to the ruby ring he wears. If it's removed from his finger, he will instantly die and his body will shrivel.
** ''The Fungi from Yuggoth'' adventure "By the Bay Part I". Lang Fu's Coat of Life has allowed him to live for centuries. If it is ever removed for more than a few minutes, his body will begin an [[RapidAging irreversible aging process that will cause his rapid death]].
* In ''TabletopGame/{{Warhammer 40000}}'', the life of the [[GodEmperor God-Emperor of Man]] is preserved by technology in his throne. Probably influenced by the ''Runestaff'' books; certainly much better known nowadays. One of the signs of the Imperium's gradual decay is that the Golden Throne is starting to fail.
** A better example would be the Gene-seed. One of the fringe benefits of becoming a [[SuperSoldier Space Marine]] is that you become incredibly long-lived, if not immortal. [[CaptainObvious Of course]], [[BlessedWithSuck it isn't all sunshine and roses]]. More well-off Imperial civilians can afford the Juvenat process, which staves off aging.
** For Chaos Space Marines, the powers of the Warp allow you to stave off aging. Again, [[DealWithTheDevil considering]] ''[[DealWithTheDevil where]]'' [[DealWithTheDevil you get the immortality from]]...
** The Craftworld Eldar use Soulstones to capture their souls upon death and put them into stasis [[note]]if you're wondering why they do is, there is a ''[[EldritchAbomination very]]'' [[FateWorseThanDeath good reason]][[/note]], where they're either placed in an Infinity Matrix, or a wraith construct. It's actually a pretty good deal, if you don't mind becoming either a) a ghost who will probably spend eternity giving out advice and information to the living, or b) a {{Golem}}-esque war machine who will probably spend eternity fighting the craftworld's enemies.
*** The Dark Eldar cheat death in a much more sinister fashion, naturally. They capture slaves and feed on their souls and suffering to rejuvenate themselves. They're basically [[OurVampiresAreDifferent vampires]]... [[RecycledInSpace IN SPACE]]!
** The Necrons were once incredibly short-lived beings who longed for immortality. One day, they were approached by {{Eldritch Abomination}}s who offered for them to be transferred into metal bodies. This turned out, of course, to be a stupendously bad idea; said horrors enslaved and brainwashed them. Nearly all of them have lost their higher-level functions and are now effectively mindless drones, and the ones who still retain free thinking and self-control are batshit insane.

[[folder:Video Games]]
* The TropeNamer is the +ii emitter in ''Videogame/IMissTheSunrise'', affectionately referred to as the "immortality inducer" by some characters. It works by emitting radiation that stops cell aging, and is mass-produced, effectively making the entire human race immortal. It induces type II immortality.
** In the sequel, ''VideoGame/TheReconstruction'', it is also [[spoiler:the "artifact" that Havan finds. Tezkhra reveals in the GoldenEnding that there are five in total. Four are destroyed or deactivated by Tezkhra, so the fifth is likely a SequelHook.]]
* ''VideoGame/WarGods'' features a mystical stone known as the Ore. Induces eight humans, one cyborg and one stone idol to immortality thanks to many chunks of ore. As a result, [[ThereCanBeOnlyOne they're fighting each other until one becomes the true superior God]]... ([[ExcusePlot or so it seems.]])
* [[spoiler: Jacob Crow]] in ''VideoGame/TimeSplitters'' achieves immortality by merging himself with one of these, or turning himself into one, it would seem. The good? He is immortal and can time-travel at will. The bad? His [[BodyHorror body is plastered to a giant bipedal mech, and he has absolutely no hands whatsoever]].
* In ''MetalGearSolid4'', [[spoiler:Vamp, who previously demonstrated his immortality in ''MetalGearSolid2'', is revealed to have nanomachines [[DoingInTheWizard (what else?)]] in his body that enhance his already impressive [[HealingFactor natural healing abilities]], making him practically immortal. Naturally, the only way to beat him later on is to inject him with a shot that supresses his nanomachines.]]
* The ''VideoGame/{{Touhou}}'' series has the Hourai Elixir, which was literally created by distilling the concept of eternity into liquid form. It makes whoever drinks it immortal by removing the very concept of death from their being: they will never age, never grow sick, and will heal any injury, no matter how severe (even ''instantly'' in Kaguya's case, due to her other power). The closest one can get to defeating one is beating them down until the pain makes them not want to fight you anymore. Even if you could time-travel to before they drank the elixir and tried to kill them then, it ''still'' wouldn't work; death was removed from the ''entirety'' of their history. Fortunately, only three people have consumed the Elixir, and noone of them is particularly interested in a fight to the death ([[CycleOfRevenge except between]] two [[RevengeBeforeReason of them]]). The Elixir remains in the immortal's body - should someone be skilled enough to disable a Hourai immortal and eat his or her liver without cooking it, they will also be granted the effects of the Elixir.
* ''Franchise/{{Pokemon}}'':
** In ''VideoGame/PokemonRanger: Guardian Signs'', [[spoiler:The Societea become immortal by wearing pieces of the Golden Armor. This seems to be of the "stop the aging process and survive mortal blows" kind, but we never actually see them suffer any direct physical harm until after they lose their armor to [[TheStarscream Purple Eyes]], so we can't be sure about the latter. After Purple Eyes is defeated, the armor disappears, thus making sure no one remains immortal.]]
** In ''VideoGame/PokemonXAndY'', [[spoiler:the Ultimate Weapon]] can grant eternal life.
* The Heart of Chaos serves this purpose for Caius of ''VideoGame/{{Final Fantasy XIII-2}}''. As long as it beats in his chest, he always revives instantly after being defeated, {{Justified|Trope}} via him having the Auto-Raise status boost. If it's destroyed, he dies [[spoiler:and so does the goddess who gave it to him.]]
* Miss Fortune of VideoGame/{{Skullgirls}}, upon swallowing the Life Gem. She was cut into pieces shortly afterwards, though not only did she survive the ordeal, the gory extent of splitting apart her undying body is utilized in her fighting style.
* ''VideoGame/TheLegendOfZeldaMajorasMask'': Igos du Ikana, Igos du Ikana's bodyguards, Flat, Sharp and every undead inhabitant of the Ikana Canyon revived by Skull Kid wearing the Majora's Mask and mantained alive by Twinmold.
* [[BigBad Mundus]] in ''VideoGame/DMCDevilMayCry'' is an immortal demon lord in Limbo. However, the human body he uses to control events in the real world as a CorruptCorporateExecutive is as mortal as any other human. The Hellgate in his office serves the dual purposes of preventing most humans from seeing demons (Dante's psychic ally Kat is one exception) and ensuring that he is still immortal as a human. Vergil's entire plan consists of finding a way to make Mundus angry enough to leave the Hellgate unguarded so Vergil can shut down the Hellgate, exposing the existence of demons to humanity and rendering Mundus mortal.
* The Twenty-seven True Runes in the Suikoden games will stop their bearers from aging.
** However, given the nature of the True Runes, you're more likely to die just by ''having one''.
* ''VideoGame/DarkSouls'' has the Primordial Crystal, which grants immortality to [[spoiler:Seath the Scaleless, who stole it when he defected from the Eternal Dragons. Having been born without the scales that granted his species their immortality, the crystal gave him exactly what he wanted most.]]
* The Eye of Isis artifact in ''VideoGame/TombRaider III'' can apparently grant its bearer immortality or at least have drastically slow aging. Cosmetics tycoon Sophia Leigh posses the Isis and uses it in conjunction with her experiments to get true everlasting beauty. Unfortunately, all the people she experimented on were LeftForDead after their face and flesh rotted away and got booted down to the abandoned train tubes of Aldwych. When the men who were affected by the experiment tried to kill themselves, they discovered that it didn't work because they became immortal.

[[folder:Web Original]]
* From the Wiki/SCPFoundation, there's [[ SCP-963]], a talisman which, if you are killed while holding it, is imprinted with your soul. From then on, anyone else who touches the talisman has their personality overwritten with whoever is contained inside. It's actually possible to make multiple copies of yourself this way.
** Unfortunately, SCP-963 currently belongs to the [[BunnyEarsLawyer quite-possibly-insane]] Dr. Bright, which led to several (actually pretty funny) restrictions such as "SCP-963 is not a joy-buzzer.", "SCP-963 is not to be used in a game of 'hot potato'.", and "Dr. Bright is not allowed to apply SCP-963 to any major political figures. Again."
** Anyone who touches [[ SCP-596]] is kept alive forever until they release it, even regenerating from any injury. Not that you would want to be however, since you're kept alive in permanent agony, and the only way to let go is for someone else to touch it at which point it's their problem and you instantly die. Its heavily hinted that it was a booby trap to curse tomb robbers with a case of AndIMustScream.
* In ''Webcomic/{{Jix}}'' Kelelder the Planet Thief was made immortal due to a glitch in a cloning and mind transfer device. He's also made a couple of servants immortal using his blood, Heleatra too due to a deal with Remula.
* The Guardian Emerald in SonicTheComicOnline when Knuckles died, it would always resurrected him, but when then Floating Island's systems fell into disrepair most of Knuckles's memories were lost, as such he does not know the fate of his race and for it to work a being from the spiritual plane must be willing to exist in the mortal realm, unfortunately for the Echidnas, and perhaps all of Mobius, the only willing candidate was Vichama, the God of Death. [[/folder]]

[[folder:Western Animation]]
* The Dog talisman in ''WesternAnimation/JackieChanAdventures'' gives someone immortality with youthful energy, but (the baddies, at least) can still feel pain from blunt force trauma. The Horse Talisman could probably provide FromASingleCell-type immortality, although its regenerative powers was never taken to the limits in the show. Together, they provide CompleteImmortality.
* Starscream, in ''TransformersAnimated'', becomes immortal due to a shard of the [=AllSpark=] lodged in his head. [[spoiler:Prowl removes it in the series finale.]]
* In ''WesternAnimation/{{Gargoyles}}'', Demona and Macbeth are each other's immortality inducers. As long as one is alive, the other cannot die. The only way either of them can die is if they [[MutualKill kill each other.]] By the time of his first appearance in the series, [[WhoWantsToLiveForever after hundreds of years living this way, this is exactly what Macbeth wants]]
* In ''WesternAnimation/AdventureTime'', [[spoiler:the Ice King's Crown]] grants its wearer, among other things, immortality.
* In the ''WesternAnimation/XMen'' animated series, the secret to Apocalypse's immortality is the Lazarus Chamber, an ancient device located inside his pyramidal headquarters in Cairo. It allows him to rejuvinate himself every hundred or so years and restore his power to its prime.

[[folder:Real Life]]
* Certain mutations in genes such as BRCA 1, Rb, c-Myc ''et al.'' can prevent your cells from dying after a preset number of divisions. Unforunately, scientists call this condition ''cancer''. So while your individual cells become immortal (the tumour cells taken from the body of Henrietta Lacks are still alive today; they will continue to live as long as the field of biology exists), but ''you'' will die.