%% This list of examples has been alphabetized. Please add your example in the proper place. Thanks!
[[quoteright:350:[[Literature/TheBible http://static.tvtropes.org/pmwiki/pub/images/Ghent_Altarpiece_A_-_Cain_-_Abel_-_murder.jpg]]]]
[[caption-width-right:350:[[TropeNamer The brothers]], [[BlatantLies "ironing" out their differences]].]]
[-[[caption-width-right:350:[[https://en.wikipedia.org/wiki/Ghent_Altarpiece Image]] by Hubert and Jan van Eyck]]-]

->Then the Lord said to Cain, “Where is Abel your brother?” He said, “I do not know; am I my brother’s keeper?”\\
And the Lord said, “What have you done? The voice of your brother’s blood is crying to me from the ground."
-->-- Literature/{{Genesis}} 4:9-10

Sometimes SiblingRivalry can get a little… intense. Maybe one who MissedTheCall [[TheRival gets]] overly [[GreenEyedMonster jealous]] that the other has become TheChosenOne, maybe grand powers or knighthood run in the family and one just happens to have been tempted to TheDarkSide, maybe one of them [[DeceptiveDisciple betrayed their master or father]] and the other has to stop him, or maybe it's just BecauseDestinySaysSo, dammit. Whatever the case may be, now one's the hero and one's the villain, and they must do battle. Commence the angst.

For whatever reason, the older sibling is almost always the villainous one. Probably because being younger and less experienced makes the [[YoungestChildWins younger sibling]] the underdog, whom we are supposed to root for. And because the AloofBigBrother always looks eviler. The major exception is the case of TheEvilPrince, who is usually the younger of two princes, and who will do anything to make sure ''he'' succeeds their father instead of his brother (or in the case of the prince being the ''king'''s brother, to take the throne for himself directly).

It's not always siblings--ChildhoodFriends get to experience all the same woes from beating up someone they grew up with--but there's a certain poetry when they're [[ThickerThanWater actually related]]. Note that they are traditionally always of the same sex: brothers or sisters (though there are exceptions).

In cases where the Cain turns out to be TheUnfavourite, he's likely to be viewed from [[SympatheticPOV a more sympathetic angle]]. Of course, this would partially also depend on the sibling's attitude in all this. Sometimes the siblings will become TheOnlyOneAllowedToDefeatYou, or realize they're NotSoDifferent. If the hero isn't aware of the relation until late in the series, it's also a LukeIAmYourFather. WeUsedToBeFriends and EvilFormerFriend also counts if the siblings in question were former friends with each other. Compare OedipusComplex. Contrast SiblingTeam. Also contrast BashBrothers, where the two people (who may or may not be brothers) beat up other people instead of each other. When Cain is gunning for mom and dad instead of Abel see AntagonisticOffspring.

The trope title, of course, comes from the biblical story of the first siblings to exist. See also NameOfCain. When ThereIsAnother, compare CainAndAbelAndSeth. May overlap with BigBrotherBully if said bully is truly malignant. If not a Good vs. Evil situation, see SiblingRivalry.


** CainAndAbel/{{Literature}}


[[folder:Anime & Manga]]
* In ''Manga/{{Area 88}}'', the Asran civil war was started by two royal brothers--King Zak and Prince Abdael--with different visions for the future of their country. Tensions erupted years before the conflict, when their father chose the younger brother (Zak) to succeed him.
* ''Manga/AstroBoy'' has Astro and Atlas.
* In ''WebComic/AxisPowersHetalia'', the characters of China and Japan enact this trope in their BackStory, with China as the Abel (despite being the elder) and Japan as the Cain. Japan was raised by China as his younger brother, yet never really considered himself his brother, and in the end he injures China with his katana and abandons him. Even when they're shown later to be in more civil terms, the bad blood is not exactly gone.
** The character of "Korea" represents only South Korea, due to the obvious RealLife issues surrounding the two countries in the peninsula. When fanworkers create an OriginalCharacter representing North Korea (sometimes male, sometimes female), they and South Korea end up recreating this trope as well.
** Due to the [[NationsAsPeople nature of the show]], there's really a lot of this going on: [[LoveFreak America]] and [[{{Tsundere}} England]] have this dynamic in America's flashback about his revolution (which [[LoveHurts England is still upset about]]), too, and anytime fanwork depicts a conflict between two related nations it becomes this very quickly.
** {{Fanon}} characters 2P!America and 2P!Canada are generally depicted like this, too, with 2P!Canada as the Abel to 2P!America's Cain.
* In ''Manga/BetrayalKnowsMyName'', it turns out that Kanata, Yuki's childhood friend from the orphanage where he grew up, who was like an older brother to him, is actually [[spoiler:Reiga, the BigBad]].
* In ''Anime/BloodPlus'', a natural scientist finds Saya and Diva's mother's corpse and hatches the infants from their cocoons ([[OurVampiresAreDifferent it's complicated]]). As part of an experiment, he raises Saya as his own daughter and locks Diva in a tower to be a guinea pig. Saya is raised as a normal human girl; Diva is experimented on and denied anything more than a blanket and a meagre amount of food. Saya grows up seeing humans as equals; Diva grows up seeing humans as torturers and also food. One day Saya meets Diva and lets her out. The resulting bloodbath started a conflict between the two sisters that lasted for over a century.
* ''Manga/BlueExorcist'':
** The tragic aspect of this ''almost'' happens to Rin (HotBlooded AntiAntiChrist) and Yukio (genius exorcist and Rin's younger twin brother) when the former discovers he's the son of Satan and then learns that the latter ''knew it all along'' and now wants to kill him ([[DefiedTrope they get better]]) but there ''are'' still hints that [[spoiler:Yukio is more susceptible to the dark side]].
** Secondary case with [[spoiler: the other two sons of Satan]], Mephisto Pheles (AKA Johann {{Faust}} V) and Amaimon: Mephisto is outgoing and clownish (similar to [[Manga/DGrayMan The Millennium Earl]], complete with umbrella) while Amaimon seems to be quieter and darker.
* ''Manga/ChronoCrusade'' uses this trope not once, not twice, but ''three'' times.
** Aion and Chrono, as they often seem to be [[HoYay even more]] than brothers… in the manga Aion and Chrono were close friends and described as "like brothers"--demons in the series are BeePeople and don't exactly have the concept of family. [[spoiler:Except Chrono and Aion were turned into demons when their (human) mother was pregnant with them--[[LukeIAmYourFather they're twins]].]] Aion is rather obsessed with getting Chrono back on his side, although when he refuses Aion gleefully tortures him for it. The anime version makes the pair have a more distant relationship, but also implies that they're two sides of the same coin. (Not to mention giving the pair their fair share of HoYay.)
** Meanwhile, Rosette [[DealWithTheDevil made a contract]] with Chrono in order to save her brother, Joshua, after he was kidnapped by Aion. It turns out that Joshua is radically devoted to Aion (partially because he's been given power that [[ComesGreatInsanity drives him mad]]), which causes the pair to fight… when Joshua remembers Rosette is his sister at all.
** Satella reveals early on that [[ChekhovsGunman she's searching for her missing sister.]] [[spoiler:Guess who also happens to be working for Aion? Her sister Florette, now called "Fiore".]] When this is revealed the pair naturally ends up fighting each other.
* [[TheAtoner Ogami]] and his older brother from ''Manga/CodeBreaker''. They're even [[DarkIsNotEvil color]] [[LightIsNotGood coded]]!
* ''Anime/CodeGeass'': Lelouch and Suzaku, in the childhood friends variety, although for a while they aren't even aware they're on opposite sides. It kicks into high gear after the WhamEpisode, though, when one of them ends up killing someone they both loved. Not only that, but the whole driving force behind the plot is Lelouch's revenge-fueled crusade to slaughter almost his ''entire family'' aside from his little sister.
* In ''LightNovel/{{Corsair}}'', Jean-Hughes blamed Canale for everything that went wrong with their family and tried to kill him several times as a child (thinking he succeeded). When he finds out Canale is, in fact, still alive he continues to plan to do him off. While Canale has a lot of blood on his hands at this point, Jean-Hughes is clearly the "evil" brother and [[spoiler:in the end Canale kills him instead]].
* In ''[[Manga/CountCain Cain Saga]]'', Earl Cain is, ironically, the Abel to his psychopathic and [[BastardBastard illegitimate]] elder half-brother [[spoiler: Jizabel]].
* Heine is the Abel to Giovanni's Cain in ''Manga/DogsBulletsAndCarnage'', although they aren't blood brothers but were simply raised in the same research facility by the same MadScientist "mother".
* Goku and Raditz from ''Anime/DragonBallZ''. Cooler, Freeza's StrongerSibling, notes that they would have been this sooner or later if Goku hadn't beaten Freeza first.
* [[spoiler:Holland]] and [[ColonelBadass Col.]] Dewey Novak in ''Anime/EurekaSeven''.
* Agon and Unsui of ''Manga/{{Eyeshield 21}}'' seem to be set up as this at first, with the younger sibling being blessed with unlimited talent and the elder having to suffer hellish training just to be half as skilled. However, while there's definitely some tension between them, the older brother ends up being more dutiful to the younger rather than hateful.
* ''Manga/FairyTail'' has Natsu and [[spoiler: Zeref]], once [[LukeIAmYourFather the revelation]] comes out.
* ''Manga/FistOfTheNorthStar'': The villains, Raoh and Jagi, are the series's Cain to Kenshiro and Toki's Abel. Though Kenshiro and Jagi's relationship is more direct (with the former killing the latter instead of the other way around), NobleDemon Raoh subverts this. [[spoiler: While he defeated Toki in combat, Raoh sheds enormous amounts of TenderTears, knowing his condition due to radiation sickness]]. Raoh and Kenshiro also has their first and final battles. While the first fight between the two is seemingly played straight, the final one isn't. Raoh held his brother's face like a true big brother after his defeat.
* In the ''Anime/FullmetalAlchemist'' anime, the homonculus [[spoiler:Envy]] turns out to be [[spoiler:the result of attempted resurrection of Hohenheim and Dante's son, making him Ed and Al's older (by a few hundred years) brother]]. This is foreshadowed repeatedly through the series, with much of [[spoiler:Envy]]'s actions being a result of [[spoiler:his, well, [[MeaningfulName Envy]] of Ed and Al for being their father's favourites, as well as a burning hatred for his father. Envy even ends up killing Ed (albeit temporarily) like the TropeNamer, for bonus points in this trope.]]
** The trope is in action in a truly bizarre way in the [[Manga/FullMetalAlchemist manga and]] ''[[Manga/FullMetalAlchemist Brotherhood]]'' [[Manga/FullMetalAlchemist anime]], where BigBad [[spoiler:Father]] was created from Hohenheim's blood, making him Ed and Al's spiritual and biological brother, and his children, the Homunculi, their nieces and nephews.
* Another childhood friends one: Miaka Yuuki and Yui Hongo in ''Manga/FushigiYuugi''.
* [[spoiler:Kagura]] and [[spoiler:Kamui]] of ''Manga/{{Gintama}}'', estranged siblings who would probably have gotten along [[spoiler:were Kamui not such a jerkass (trying to kill your dad then disappearing for years is not the way to forge strong family bonds). As it is, Kagura considers all their bonds severed and Kamui seems to want little to do with her.]]
* ''Anime/GlassFleet'': [[spoiler: Vetti and Cleo.]] Though they don't know they're related until the very end of the series, combining this with the Separated at Birth trope.
* In ''Anime/GodMars'', the relationship of Takeru with his brother Ma, which fate would have it, pitted the two against each other in the war.
* ''Franchise/{{Gundam}}'' has a lot of them:
** ''[[Anime/MobileSuitGundamSEED Gundam SEED]]'' gets Kira and Athrun, who're the childhood friends version. Unusual in that neither is really a villain, and both end up in a third faction after both sides they worked with turn out to be villainous. Though not before a climactic and nearly fatal final duel halfway through the series, naturally.
*** There's also Mu La Flaga and his father's clone [[spoiler:Rau Le Creuset]]; one is TheAce, the other the BigBad.
** Kyouji Kasshu and his little brother Domon from ''[[Anime/MobileFighterGGundam G Gundam]]''… [[spoiler: Or so we think. ]]
** Ginias Sahalin from ''Anime/MobileSuitGundamThe08thMSTeam''. We meet him as Aina's caring-but-aloof brother. Twelve episodes later we bid farewell an obsessive, murderous mad scientist who forces his once-beloved sister to pilot his giant mechanical monstrosity, tells her that "Love is an ''illusion''', produced by your body's glands!", and then shoots her. (This is between blowing up/poisoning his allies, working his minions to death, and destroying perfectly good viewscreens.) She doesn't really object when her Main Character boyfriend tells her "Sorry, but I have to kill your brother now", even when she's not exactly happy either.
** ''Anime/MobileSuitGundamUnicorn'': [[spoiler:Alberto is The Half brother and Cain to Banagher and his Abel]]
** In the original ''Anime/MobileSuitGundam'' we have [[TheBaroness Kycilia]] and [[TheEvilPrince Gihren Zabi]], a pair of cold-blooded {{Manipulative Bastard}}s and social climbers who are perfectly willing to kill one another if it means ascending to control of the family. More like Cain and Cain really.
* ''VisualNovel/HigurashiWhenTheyCry'' involves this with the twin Sonozaki sisters, Mion and Shion, as one of the two is the only one (besides those who already knew the whole story) who doesn't get infected with the HatePlague, while the other, when infected, throws her conscience out the window even ''before'' she loses her mind and racks up the highest body count in the series besides [[BigBad the instigator herself]]. Yes, the elder is the "evil" one--[[spoiler:the murderer was Shion pretending to be Mion most of the time, but because of a mix-up in their childhoods, the elder girl, originally named Mion, ended up living as Shion due to a TwinSwitch, so Mion was pretending to be Shion pretending to be Mion.]]
* In ''Manga/HonooNoAlpenRose'' we have the sibling version with [[spoiler: the Courtot brothers. Older brother Jean-Paul is a ColdSniper hitman Cain, younger brother Lundi is an ActionSurvivor Abel.]]
** In the manga, there's also [[spoiler: the Toulonchamp sisters. Older sister [[DefectorFromDecadence Madeleine]] is the Abel, while little sister [[DaddysLittleVillain Mathilda]] is the Cain.]]
* ''Manga/InuYasha''
** As a result of Inuyasha claiming the sword Sesshoumaru's been pursuing for years, their SiblingRivalry escalates into this trope for a while, mainly due to Sesshoumaru's belief that Inuyasha's claim proves he's TheUnfavourite he's always secretly feared he was. This is eventually resolved.
** Ginka and Kinka are from a {{youkai}} race where two heads (with associated identities and personalities) are born to a single body and one personality must kill the other (and devour the defeated head) before they reach adulthood because it's the only way their race can survive. Unfortunately for everyone, Ginka and Kinka have made it to adulthood, both alive, both still firmly attached to each other, and both still trying to kill the other. Their fight can lay entire villages to waste. It's so bad they even have to negotiate when they go to sleep and for how long just in case one takes advantage of the situation.
* Tsubasa and Souma Ohgami from ''Manga/KannazukiNoMiko'', though [[spoiler:Tsubasa isn't really a bad guy and undergoes a rather spectacular HeelFaceTurn late in the series.]] What's more, technically, they are both Necks of {{Orochi}}, only that Souma has a good reason to fight against his "heritage".
* Belphegor and Rasiel from ''Manga/KatekyoHitmanReborn'', possibly subverted in the fact that [[spoiler: Rasiel isn't dead.]]
* Kazuya and Kyoshiro from ''Anime/ShatteredAngels''. [[spoiler:No, Kazuya doesn't commit any redeeming acts like Tsubasa.]]
* Subaru and [[spoiler:the [[QuirkyMinibossSquad Numbers]] [[HollywoodCyborg Cyborg]] Nove]] in ''Anime/MagicalGirlLyricalNanohaStrikerS'', a case where the good one is the older sibling [[spoiler:[[TrulySingleParent by virtue of being an earlier Quint clone]]]]. [[spoiler:Of course, this being ''[[DefeatMeansFriendship Nanoha]]'', [[HeelFaceTurn this stops being the case by the end of the season]]]].
* ''Anime/MawaruPenguindrum'': [[spoiler: Kanba]] is the Cain to [[spoiler: Shouma]]'s Abel, largely because [[spoiler: Kanba is in love with Himari, their (un)related sister and believes he has an obligation to protect her]] but [[spoiler: Shouma saved her when she was younger (''and'' he also saved Kanba when they met)]], and also disagrees about how [[spoiler: Kanba has become more and more embittered, desperate and extreme in his methods in order to [[AlwaysSaveTheGirl save Himari]] while Shouma is much more honourable and still believes things can be done without such extremes.]] It leads to [[spoiler: QUITE the showdown, in which ''both'' guys get into a fist fight, before the last episode sees them face off.]]
** There is also [[spoiler: Masako]] who is an Abel [[spoiler: herself to Kanba, as his twin sister who desperately wants him to come back home after he made a deal with their DisappearedDad to protect Masako ''and'' their little brother Mario from danger]].
** [[spoiler: Kanba in general]] is portrayed as a much more sympathetic version of Cain in general, as his reasons to be in such a position are less about his own benefit and more about [[spoiler: genuinely but VERY misguidedly wishing to save Himari.]]
* Johan Liebert and Nina Fortner from ''{{Manga/Monster}}''.
* Tiger (older) and Gray Wolf (younger) in ''Anime/MonsterRancher''. The roles are inverted with Tiger being the Abel to Gray Wolf's Cain. It's tragic because Tiger was a well-intentioned AloofBigBrother who wanted to toughen his brother up. Unfortunately, this only fueled Gray Wolf's inferiority complex. And once [[BigBad Moo]] captures Gray Wolf, he [[MoreThanMindControl magnifies these insecurities]] to the point Gray Wolf becomes a full-blown GreenEyedMonster who wants to ''kill'' his own brother, much to Tiger's horror.
* Prince Kaito from ''Manga/MurderPrincess'' is of TheEvilPrince variety. Though the actual Princess Alita (his younger sister) doesn't really fight him, as she previously [[FreakyFriday switched bodies]] with the ActionGirl Falis who handles the fighting part for her.
* Michio Yuki from Creator/OsamuTezuka's manga, ''{{Manga/MW}}'', has this kind of relationship with his lookalike older brother, Tamanojo Kawamoto.
* ''Manga/{{Naruto}}'':
** Sasuke and Itachi Uchiha. To some degree, Hiashi and Hizashi Hyuga.
** While they are cousins rather than siblings (although Hinata thinks of Neji as a brother) Neji is quite bitter toward Hinata and initially sees her as almost completely worthless until he loses to Naruto and [[HeelFaceTurn rethinks his worldview]]. Hanabi's relationship with her older sister Hinata is not this trope,as both sisters love each other very much.
** It's [[spoiler:revealed that the history of the Uchiha clan and Konoha is based on this. Essentially the Uchiha and Senju clans are descended from the elder and younger sons of the first ninja. The elder Uchiha brother was the Cain whilst the younger Senju brother was the Abel]]. Turns out that these two men were the grandchildren of [[spoiler: a princess who ate the forbidden fruit from the God Tree, much as the Trope Namers were the sons of Eve.]]
* ''Manga/OnePiece'':
** Marshall D. Teach and Thatch. On the crew of the great pirate Whitebeard, all of his crew mates are considered his adopted children; likewise, they consider him "father," and one-another brothers. Since Teach and Thatch were crew mates, the former killing the latter players this trope surprisingly well.
** The reason Trafalgar Law has it in for Doflamingo is because [[spoiler:Doflamingo murdered his own younger brother Corazon, whom Law deeply admired. Ironically, Doflamingo had been grooming Law to take Corazon's place in his crew.]]
* Hana and Ageha from ''PapillonHanaToChou'': Hana is a popular city girl and a little [[ManipulativeBitch manipulative]] while Ageha is plain country girl and [[TheWoobie walked all over]]. When Hana steals Ageha's potential love interest, Ageha is nearly DrivenToSuicide. Their mom is a [[WellDoneSonGuy Well Done Daughter Gal]] to boot: Ageha was sent to the country because her constant crying aggravated her post-partum depression. [[spoiler: As Ageha gains confidence she and her mom's relationship improves while Hana's behavior gets worse: Her latest scheme to ruin her sister's life caused Ageha's current boyfriend to break up with her, although [[HotForStudent they shouldn't have been together in the first place]](eh, if he couldn't tell them apart he's probably not worth it anyway)]]
* ''Manga/PrincessResurrection''. All the royal siblings virtually are fighting to the death for the throne except for the main character Hime who has no interest in it.
* Pops up in season 2 of ''Anime/PrincessTutu'', when [[spoiler:Mytho becomes tainted with Raven's blood]] and performs a FaceHeelTurn. [[spoiler:Fakir]] is constantly forced to fight against him, even though they were practically raised as brothers.
* It's hard to avoid in ''Manga/RozenMaiden'', where ThereCanBeOnlyOne of seven sisters that survives [[spoiler: (unless that cryptic statement at the end of season two has anything to say about it)]]. Suigintou and Shinku in particular have exactly this relationship, although who is the betrayer and who is the good underdog switches around in different points of the timeline.
* In ''Manga/SaintSeiya'', Kanon (younger) and Saga (older). [[spoiler: In the beginning, Kanon was evil and Saga was good, but Saga went insane for having a SuperpoweredEvilSide (coms with being the *Gemini* Saint, of all Gold Saints) and turned evil. Kanon *knew* his brother would become evil and used it to his advantage, staging an epic GambitRoulette that covers several arcs of the story (two in the manga, three in the anime), where Saga was the first BigBad and Kanon was the ManBehindTheMan from both him ''and'' his boss. However, later Kanon pulls a HeelFaceTurn and joins the good guys, while Saga turns evil… apparently.]].
** Phenix Ikki (older) and Andromeda Shun (younger) were at first like this. Still, Ikki pulls a HeelFaceTurn early in the story and joins the FiveManBand.
** Apparently Kurumada loves this trope very much because now in ''Next Dimension'' [[spoiler: we get the real Abel and Cain, and once again Cain is the older one.]]
* ''Manga/SaintSeiyaTheLostCanvas'' is rife with this.
** [[PhysicalGod Sasha]] and [[EvilFormerFriend Alone]], a brother and a sister who are actually reincarnations of [[ThePowerOfLove Athena]] and [[OmnicidalManiac Hades]] and are in war against each other for the fate of humans. Sasha is Abel and Alone is Cain.
** [[TheHero Tenma]] and Alone play the childhood friends version of this, with Tenma as the Abel and Alone as the Cain.
** [[ActionGirl Yuzuriha]] and her younger brother Tokusa, [[spoiler: who awakened as a Specter after [[SelfMadeOrphan killing their parents]].]]
** Another childhood friends version comes into play with [[AnIcePerson Aquarius Degel]] and [[spoiler:[[GrimUpNorth Sea Dragon Unity]], who decided it would be cool to revive Poseidon.]] [[spoiler:Unity]] eventually has a HeelRealization, but Pandora [[TooDumbToLive wrecks everything]], and Degel has to [[spoiler:[[HeroicSacrifice freeze himself along with the entire city of Atlantis to prevent Poseidon's awakening.]]]]
** As usual, the [[spoiler:Gemini Saints]] end up playing this trope. It's [[SubvertedTrope subverted]] in that, while [[spoiler:[[TheUnfavorite Defteros]]]] was treated badly in the Sanctuary, it was [[spoiler:[[TheChosenOne Aspros]]]] who became the [[spoiler:EvilTwin]], due to a growing fear of [[spoiler:Defteros]]' determination to become his brother's equal. He tried to use [[spoiler:Defteros]] [[BrainwashedAndCrazy as a pawn]] to kill the Pope (no, not [[UsefulNotes/ThePope that Pope]]), and wound up [[spoiler:getting killed by Defteros.]] [[spoiler:When he was [[BackFromTheDead revived by Alone]], he and Defteros had their face-off, and Defteros made a HeroicSacrifice to restore Aspros' sanity. When Aspros realized [[HeelRealization what]] [[HeelFaceTurn had]] [[RedemptionEqualsDeath happened]]…]]
* Teru and ''{{Manga/Saki}}'' were once close while growing up, but an incident during their childhood, the full details of which have not been revealed yet, resulted in their parents separating, [[SolomonDivorce each taking custody of one of their daughters]], and Teru hating Saki enough to stop talking with her and even [[IHaveNoSon deny having a sister]]. Saki's goal in the series is to face Teru in mahjong and somehow reconcile with her.
* Prince Forsis and Pacifica in ''LightNovel/ScrappedPrincess''. You know…
* Asakura Yoh and [[spoiler:his older twin brother Hao]] in ''Manga/ShamanKing''
* Sisters Rally and Rosa Cheyenne fall into this in ''Manga/SilentMobius.'' In this case, the elder sister (Rally) is the good one.
* ''Manga/SoulEater'' has [[spoiler:Asura (Cain) and Death the Kid (Abel). As this is revealed to Kid only in the finale, he barely has time to deal with this fact before his 'older brother' is [[SealedEvilInACan imprisoned]] once more. Up until this point he had thought [[MadGod Asura]] was merely his [[GrimReaper father's]] adversary. Recognising that a fight between AnthropomorphicPersonifications could potentially cause [[ApocalypseHow Metaphysical Annihilation]] if either invokes their RealityWarper abilities Kid rejects his brother's WeCanRuleTogether offer and decides to TakeAThirdOption by siding with [[HumansAreSpecial humanity]].]]
** Also had Masumune (Cain) and Tsubaki (Abel).
* The sisters Harulu and Karala from ''Anime/SpaceRunawayIdeon'' are an archetypal example: the [[AloofBigBrother older, more socially awkward but decisive]] Harulu grows jealous of the [[LoveYouAndEverybody dreamy, honest but romantically successful]] Karala and shoots her to death (during the KillEmAll), only realizing her true reasons afterwards.
* In ''Manga/{{Spiral}}'', Ayumu is struggling with the shadow of his elder brother [[TheChessmaster Kiyotaka]], [[spoiler:although they don't actually ''fight'' until]] the end of the manga. Also Kanone and the other Blade Children, as they were childhood friends (and, again only in the manga, [[spoiler:actually also all half-siblings]].
* ''Anime/StrainStrategicArmoredInfantry'': Sara is happy, bright, and has an enormous case of BigBrotherWorship. Then Ralph, said big brother, turns out to be a psycho that wants to [[OmnicidalManiac kill all humans]], starting with [[EverybodysDeadDave the entire population of Sara's school]]. It all goes downhill from there.
* ''Anime/TekkamanBlade''. The English dub (''Teknoman'') actually names one of the brothers Cain, and ''Tekkaman Blade II'' includes the biblical Cain and Abel story in its title crawl. This is also slightly reversed: the elder brother (Takaya/Blade aka Tekkaman Blade) is good, the younger brother (Shinya/Cain aka Evil/Sabre) is evil.
** It should also be mentioned that, in the original, [[spoiler:the BigBad, Kengo/Conrad aka Tekkaman Omega, was also Blade ''and'' Evil's older brother. And their youngest sister, Miyuki/Shara aka Tekkaman Rapier, is the gentle SacrificialLamb who chooses to die through HeroicSacrifice rather than through her fatal illness]].
* In ''Anime/TransformersRobotsInDisguise'', Optimus Prime's brother Ultra Magnus shows up on Earth with a serious grudge over the Matrix of Leadership having gone to Optimus instead of him, and quite a bit of firepower:
-->'''Optimus''': He's grown a little bitter over the years.
-->'''Side Burn''': Bitter? Bitter is not sending you postcards, but this wacko… He knocked you off a cliff!
* ''Manga/{{Trigun}}'': Vash and Knives.
** These two are notably twins with no idea who's older, and the Japanese word they use for their relationship is the incredibly vague "brethren" but because of the conventions of this trope many fans tend to treat Knives as the elder brother.
** Given the vague Christian references that get tossed in, the anime scene that confuses who's supposed to be the Cain here was probably intentional: shortly after [[BigBad Knives]] kills ''[[KillAllHumans pretty much everyone else]]'', little Vash stands over him at night with a big rock trying to work up the nerve to bash his sleeping brains out. He doesn't manage it.
* ''LightNovel/TrinityBlood'': The battling twins at the center of the story are literally named, "Cain and Abel." Care to guess which of these is the villain and which is the hero? (And to REALLY beat the biblical reference over your head, their little Crusnik "sister" is, of course, named Seth. And their common maternal figure is named Lilith.) Subverted in that it was Abel who first went after Cain because he murdered Lilith.
* You've got a BigScrewedUpFamily trapped in a mansion possibly murdering each other… Given the context, it would've been astounding if ''VisualNovel/UminekoWhenTheyCry'' ''could'' have gone without invoking this trope. It's been invoked at a bare minimum, three times.
* Zero and Ichiru from ''Manga/VampireKnight''.
* Folken Lacour de Fanel (Cain) and Van Slanzar de Fanel (Abel) from ''Anime/TheVisionOfEscaflowne'', [[spoiler:though Folken goes for a HeelFaceTurn mid-series. After all he had done, though, it still takes a ''lot'' for Van to forgive him.]]
** This is a slight variation in that there's nothing personal about it from Folken's point of view: they just happened to wind up on [[WellIntentionedExtremist different sides]] of an ideological dispute. It's played straighter in [[NonSerialMovie The Movie]], which casts Folken as a straight-up GreenEyedMonster Cain over not being named heir.
* Ditto with an older example--''Anime/VoltesV'': [[spoiler:Prince Heinel and Kenichi Go]]. And unlike in most cases of this trope, they have much in common, personality-wise.
* ''Manga/{{X1999}}'':
** Kamui and Fuuma, in another friendship variety.
** The sisters Hinoto and Kanoe count as well. The younger one, Kanoe, is the evil one though.
* In ''Anime/YuGiOhGX'', Manjyome hated ''both'' his brothers. The originally had a plan to TakeOverTheWorld via business, politics, and Duel Monsters, with him providing the last. However, Manjyome really never had any say in the matter. Eventually, he realized he was just a pawn to them, and quit. He got his revenge against them in spades; when they attempted to take over Duel Academy on their own, they demanded a duel from him with him using only monsters that had Attack Points of 500 or less. Manjyome took this one step further, using only monsters with ''zero'' Attack Points, and ''still'' won, humiliating them beyond belief.
** A far worse example in the franchise was Lotten, the main antagonist of the Crashtown arc in ''Anime/YuGiOh5Ds'', who double-crossed his brother Malcolm to take over Crashtown. Of course, Malcolm was a crook himself, but Lotten was likely the only person he trusted. Bad idea; this was truly a case of NoHonorAmongThieves.
* ''Manga/ZatchBell'': Zatch and Zeno (Gash and Zeon in the original). Zeno hates Zatch because the latter received the powerful "Bao" spells. In the manga, they end up reconciling, but Zeno hates Zatch to the [[GeckoEnding end in the anime]].
* ''Manga/ShoukokuNoAltair'': Egomaniac Sultan Balaban is the Cain and his kind-hearted younger brother Prince Beyazit is the Abel, however in a twist [[spoiler:Beyazit ends up dethroning and killing Balaban to end his tyranny]].

[[folder:Comic Books]]
* Comicbook/{{Aquaman}} frequently faces off against his evil brother Orm, the Ocean Master.
** In the New 52, it's only somewhat of an example. Orm isn't portrayed as outright evil, and the two actually get along pretty well, but once Orm decided to attack the surface, it became this. The reboot also made it a case of WeUsedToBeFriends, where the two are portrayed as having been very close as teenagers.
* Pakrat the thief and his brother Rident Oly the intergalactic police officer in ''ComicBook/AtariForce''.
* ComicBook/{{Batgirl|2011}} Barbara Gordon and her brother James Jr.: In ''[[ComicBook/BatmanTheBlackMirror The Black Mirror]]'', James attempted to murder Barbara by driving knives into the arteries in her legs and then pulling one out himself. He also set his sister up in ''ComicBook/DeathOfTheFamily''.
* Since his resurrection, [[DeadSidekick Jason Todd]] has repeatedly attacked his adoptive brothers [[Franchise/{{Batman}} Dick Grayson and Tim Drake]]. It came to the point that in ''Battle for the Cowl'' he actually tried to kill them.
** [[TykeBomb Damian]] also has this toward Tim, reasoning that he would have to kill the then-current Robin to get Batman's respect. He's undergone some CharacterDevelopment since then, but there still isn't much brotherly love between him and Tim.
** In the ComicBook/{{New 52}}, [[spoiler:Owlman is (supposedly) Thomas Wayne Jr., Bruce's brother.]]
** In one story in the ''Batman Black and White'' motion comics, one of Harvey Dent's many, many attempts to become sane again is ruined because his plastic surgeon fiance had a psychotic twin sister who was even crazier than Two-Face.
* Rose and her sister, from the epic adventure ''ComicBook/{{Bone}}'' by Jeff Smith.
* Kalibak, son of {{ComicBook/Darkseid}}, is the adopted brother of Mister Miracle, the biological brother of Orion, and an enemy to them both.
* ComicBook/{{Hawkeye}} and his older brother Trickshot. Trickshot even impersonated his brother during his time with the ComicBook/DarkAvengers, just to piss him off.
* [[BarbarianHero Skaar]] and [[UtopiaJustifiesTheMeans Hiro Kala]], the twin sons of TheHulk. Hiro-Kala wanted to kill Skaar, and then himself, to finally destroy the Old Power they inherited from their mother, as he believed it would eventually destroy the universe. Main problem was that he was going to do this by crashing a Mars-size planet into Earth to destroy both worlds, in his words "sacrificing billions to save trillions."
* The Marvel versions of Hercules and Ares are bitter rivals throughout their comics histories. In ''ComicBook/TheIncredibleHercules'', ComicBook/{{Ares}}' primary reason for despising Hercules is said to be his anger that mortals favoured Hercules over him, despite all the benefits (fame, power, empire) that war brings. But he overlooks the bad things of war (death, destruction, fear and often a heavy poverty)
* Black Bolt, leader of ComicBook/TheInhumans, and his brother Maximus "the Mad".
* ComicBook/JudgeDredd and his brother, Rico. Dredd arrests Rico after he goes rogue. Twenty years later, Rico comes back for revenge and Dredd is forced to kill him.
* Lightning Lad/Live Wire and Lightning Lord in ''Comicbook/{{Legion Of Super-Heroes}}''.
* ''ComicBook/LukeCageHeroForHire'': Luke Cage and his brother Coldfire.
* ''ComicBook/ImmortalIronFist'' has the friendship version of this between Luke Cage and Davos/Steel Serpent.
* J'onn J'onnz, the ComicBook/MartianManhunter, also had his share of troubles with his evil sibling Malefic, who was responsible for wiping out the entirety of their species, before J'onn tossed him into the sun.
* ComicBook/TheMightyThor's archenemy is his adopted brother, Loki.
* Though it's never established if they're blood siblings or not, John Doe and Alfie O'Meagan from ''ComicBook/NthManTheUltimateNinja'' are same-age infants who were found and raised in the same orphanage. The series centers around John's efforts to stop Alfie from destroying the world.
* ''ComicBook/TheSandman'' and associated titles feature Dreaming versions of the original Cain and Abel. Abel is harmless, but Cain feels driven to repeatedly murder him. Furthermore, Cain won't stand for anyone else harming Abel. These versions of the characters are originally from DC's 70s horror titles.
** In a less literal example, Desire has sworn to set the Kindly Ones on his/her brother Dream. In this case, Desire is the younger sibling.
* In the ''[[Comicbook/ArchieComicsSonicTheHedgehog Sonic the Hedgehog]]'' comics, [[TheBaroness Lien-Da]] and her brother Kragok hated their half-sister Julie-Su due to their belief that their father [[ParentalFavoritism liked her]] [[FreudianExcuse better]]. Kragok's dead these days, but the rivalry between Lien-Da and Julie-Su is still going strong--and it's not helped any by Lien-Da working for [[BigBad Eggman]] and Julie-Su being [[TheLancer Knuckles']] girlfriend.
** Lien-Da's actually been on both sides of this--she and Kragok were supposed to take over the Dark Legion together after [[KlingonPromotion killing]] [[SelfMadeOrphan their father]], but Kragok set things up so that Lien-Da would be badly injured in the process, so he could cheat her out of the position.
** Going further back in Echidna history we have the twin brothers Dimitri and Edmund. Dimitri became [[PhysicalGod infused with the power of eleven chaos emeralds]] following a FreakLabAccident and tried to conquer the world. Edmund became the first Guardian and helped stop his brother's mad plans. That's just the beginning though as Edmund's descendants continued to pass on the mantle Guardians of Angel Island from parent to child, while Dimitri's descendents became the grandmasters of the Dark Legion. The two groups continue to battle each other to this very day turning a Cain and Abel scenario into a generations long blood feud.
** In a more metaphorical sense, there's Shard (the original and [[HeelFaceTurn reformed]] Mecha Sonic rebuilt by the Secret Freedom Fighters) and the current Metal Sonic (still loyal to Eggman), who view each other as brothers, with Metal dedicated to destroying Shard.
* ComicBook/BlackPanther and his adopted brother, White Wolf.
* Likewise, Shang-Chi and his adopted brother, Midnight Sun.
* ''Comicbook/{{Spider-Man}}'' had [[ComicBook/ScarletSpider Ben Reilly]] and Kaine, who were [[CloningBlues sort of]] brothers. They managed to [[NotSoDifferent work it out]] just in time for Ben to die.
** Kaine to Peter, too.
* Tambi and Bambi Baker from ''ComicBook/StrangersInParadise''.
* During a brief DorkAge, that was thankfully swept away by ''ComicBook/InfiniteCrisis'', ComicBook/{{Supergirl}}'s father Zor-El hated his brother Jor, and sent Kara to Earth to kill [[{{Superman}} Jor-El's infant son]]. Or he just didn't get on with his brother, and knew that Kal-El would "infect" Earth with evil spirits from the Phantom Zone. Or… look never mind, [[AuthorsSavingThrow it's gone]]!
* In ''ComicBook/SupermanAndBatmanGenerations'', Joel Kent, who was prenatally stripped of his Kryptonian superpowers by Gold Kryptonite exposure, was the Cain to his sister Kara's Abel, and in the same Biblical fashion ended up killing her when he got superpowers.
* Ulic and Cay Qel-Droma from ''ComicBook/TalesOfTheJedi''. There isn't any SiblingRivalry until their master is killed and Ulic's attempt to become a FakeDefector results in him ''actually'' falling to the dark side and becoming the Sith Lord Exar Kun's NumberTwo. Nevertheless, Cay stubbornly believes that there's still good in his brother and tries to talk him back even after Ulic shoots his starfighter down. [[spoiler:It doesn't work--Ulic kills him in a lightsaber duel. It's only after that when Ulic turns back out of remorse.]]
* Anyone who's a fan of the ''WesternAnimation/TeenTitans'' cartoon knows that ComicBook/{{Starfire}} and her sister Blackfire are enemies… Their hatred for each other is a ''lot'' worse in the comics.
* Starfox and {{Thanos}} the Mad Titan. Their father forced them to agree to meet once every thousand years on peaceful terms in the hopes that they would eventually stop fighting altogether. So far they haven't.
* Tomoe and her EvilCounterpart Noriko from ''ComicBook/UsagiYojimbo''.
* Heroic trucker Ulysses Solomon Archer and his villainous brother the Highwayman from Marvel's shortlived toy tie-in comic ''U.S. 1'' (and now officially part of the MarvelUniverse).
* ''ComicBook/XMen'' has a number of examples.
** Although they're both heroes, ComicBook/{{Cyclops}} and Havok frequently find themselves fighting against each other. Played straight between Cyclops and his other brother Vulcan, and played even more straight between Havok and Vulcan after the latter killed their father.
** Comicbook/{{Cable}} and his brother/clone Stryfe.
** Juggernaut '''Cain''' Marko and step-brother Charles Xavier.
** And in a metaphorical vein, Charles "Professor X" Xavier and Erik Magnus "Magneto" Lensherr--once the closest of friends, now on opposite sides of an ideological gulf on mutant/human relations.
** Also Professor X and Cassandra Nova, making him a triple header on this one.
** Banshee's cousin Black Tom is his brother in the AnimatedAdaptation.
** {{Wolverine}} and ComicBook/{{Sabretooth}} aren't brothers ''per se'', but they were both products of the Weapon X project, and at one point it was (wrongly) believed Sabretooth was Wolverine's father. Creator/ChrisClaremont has suggested that Sabertooth being Wolverine's father ''was'' the original plan.
** ComicBook/EmmaFrost and her sisters, especially Adrienne whom she shot to death after Adrienne's actions led to Synch's death.
** There's also the human Graydon Creed and his mutant half-brother Kurt Wagner/Nightcrawler.
** Now {{ComicBook/Daken}} and ComicBook/{{X 23}} can be added to the list, being the son and daughter of Wolverine. Daken is what Wolverine is trying to make sure X-23 does NOT end up like.
** Colossus and his (now currently deceased) brother Mikhael Rasputin. His relationship with his little sister Ilyana is only slightly better: Colossus is fiercely protective of her to the near detriment of every other aspect of his life, but she's a soulless demonic being (who nonetheless still loves Colossus as much as a soulless demonic being is capable of love). Eventually Ilyana forced Colossus to understand that she isn't the same innocent little sister he loved by manipulating him into suffering demonic possession as the new Juggernaut. When Colossus learned the truth, as well as the fact that Ilyana could have freed him at any time, he vows to kill her if they ever meet again. Ilyana is disturbingly pleased by this.
** In a CrowningMomentOfAwesome in ''ComicBook/AvengersVsXMen'', a badly injured ComicBook/SpiderMan manages to take down Pitor and Ilyana (both of whom have received insane power upgrades courtesy of the Phoenix Force) by tricking them into fighting one another.
* In ''Comicbook/{{Fables}}'', [[spoiler:Snow White and Rose Red]] are descended from a line of powerful female magic users. Each generation of the family has been doomed to suffer from this because their power [[ThereCanBeOnlyOne can only be inherited by one person]]. Many generations have tried to avert the trope by not fighting or not having children. So far, nothing's worked. Their mother tried to avert it in multiple ways, and failed each time. First by abstaining from the conflict, which failed when her remaining sister hunted her down anyway and she was forced to kill her in self-defense (though it's also implied she planned this all along). Then she resolved to die without bearing any children by remaining single for life, which failed when she fell in LoveAtFirstSight with a man who wandered onto her home by complete accident (implied to be destiny at work to propagate the curse). Finally, she resolved to only have ''one'' child, [[spoiler:which failed when she gave birth to the twins Snow and Rose.]] Learning all of this convinces [[spoiler:Rose Red]] that a fight to the death with her sibling is inevitable. Since she's also convinced that she would lose in a fair fight, she also resolves to fight dirty…

[[folder:Fairy Tales]]
* In "[[http://www.surlalunefairytales.com/cinderella/stories/fair.html Fair, Brown, and Trembling]]", the two older sisters refuse to let their sister out of the house for fear she would marry before them. When she succeeds in marrying anyway, her oldest sister pushes her into the sea and takes her place.
* In "[[http://www.surlalunefairytales.com/cinderella/stories/finettecendron.html Finette Cendron]]", Finette's sisters force her to stay home from the ball.
* In "[[http://www.surlalunefairytales.com/firebird/stories/goldbird.html The Golden Bird]]", the hero's [[GreenEyedMonster envious]] brothers have him ThrownDownAWell, and succeed in trapping him there.
** Similarly, the brothers in "[[http://www.mythfolklore.net/andrewlang/412.htm The Bird Grip]]" throw the hero into a lions' den, and in "[[http://www.mythfolklore.net/andrewlang/368.htm The Golden Blackbird]]", into a lake.
* In "[[http://www.mythfolklore.net/andrewlang/392.htm The Golden Mermaid]]", the [[GreenEyedMonster envious]] older brothers beat [[YoungestChildWins their younger brother]] to death. The [[TalkingAnimal talking fox]] and golden mermaid [[BackFromTheDead revive him]], and when he reaches court, the king banishes his older brothers.
* In "Literature/TheGratefulBeasts", Ferko's brothers put out his eyes and break his legs. Then they slander him to the king to persuade him to set Ferko to {{Impossible Task}}s until, finally, Ferko has wolves eat the king, his own brothers, and all the court.
* In "[[http://www.surlalunefairytales.com/authors/grimms/28singingbone.html The Singing Bone]]", the younger brother is murdered by the [[GreenEyedMonster envious]] older. His corpse rots, someone retrieves a bone from it and makes a flute, and the flute begins to sing of the murder. (Music/GustavMahler adapted this tale for his early work ''Das klagende Lied''.)
* In "Literature/TsarevitchIvanTheFireBirdAndTheGrayWolf", the [[GreenEyedMonster envious]] older brothers kill [[YoungestChildWins the youngest, Prince Ivan]]. The [[TalkingAnimal talking wolf]] puts him back together and [[BackFromTheDead restores him to life]], and they get word to his father, who turns his oldest sons into menial servants and make Ivan his heir.
** The same sort of thing happens in a large percentage of Russian fairy tales. Either there will be three brothers or three sisters. If there are three brothers, then the two oldest will be greedy and ambitious, and the youngest will be lazy, considered a fool, and usually named Ivan. The youngest brother will compete with his older brothers for something, and will always win through kindness and wisdom. If there are three sisters, the oldest two will be lazy, greedy, and vain, and the youngest will be the only one who ever does any work. The youngest will always get to marry the prince.
* In "[[http://www.surlalunefairytales.com/eastsunwestmoon/stories/unseen.html The Unseen Bridegroom]]", Anima's sisters incite her to [[ForbiddenFruit look at him at night, against his command]], because they are [[GreenEyedMonster envious]].

[[folder: Fan Works]]
* [[Franchise/AceAttorney Kristoph and Klavier Gavin]] in ''Fanfic/DirtySympathy''. While they have not hurt each other directly, there's a reason that Klavier is willing to [[FrameUp frame]] his brother and he tells Apollo outright that he would have been in Apollo's [[BadBoss posi]][[SexSlave tion]] if he hadn't left. Notably, it's the Abel who struck first, by getting the Cain sent to jail before he could do anything.
* In ''Fanfic/GettingBackOnYourHooves'', it's revealed that [[spoiler:the BigBad [[TheSociopath Checker]] [[ManipulativeBastard Monarch]] who's trying to ruin Trixie's life is actually her big sister.]]
* ''Fanfic/GraduateMeetingOfMutualKilling'' has brothers Reiji and Yukio Ohmoto. [[spoiler:The former was the Assistant, while the latter was the Master. After a blunder Yukio did was quickly (and unsuccessfully) concealed via Twin Switch, Reiji got a spot in the Administrative Council of Hope's Peak. The influence and position of that spot gave Reiji what he needed to usurp Yukio's title and past, ending with Reiji as the Master and Yukio as the Asisstant.]]
* [[NobleDemon Bataar]] and [[PsychopathicManchild Unegan]] in ''FanFic/{{Hachin}}''. Notably, it's actually the younger brother who's the Cain is this case.
* ''FanFic/InnerDemons'': [[spoiler: Sweetie Belle]] and [[spoiler: Scootaloo]] [[FaceHeelTurn join]] [[BigBad Queen!]][[FaceHeelTurn Twilight]], turning on [[spoiler: Rarity]] and [[spoiler: Rainbow Dash]], their respective sister and sister-figure. And of course, Queen!Twilight herself ends up in this relationship with Shining Armor (though that's not her [[VillainousIncest original]] plan). In all three cases, it's the younger one who's evil.
* Inuyasha and Sesshomaru, Kagoyasha and Inukyo in {{WebVideo/Inuyasha The Real World}}.
* Mufasa and Scar in ''Fanfic/TheLionKingAdventures''. [[spoiler: Although neither of them kills the other.]]
** Hago and Bora, too. [[spoiler: Hago slits his brother's throat after his first resurrection in ''The Return of Hago''.]]
* Roll and Maylu are into this in ''[[FanFic/MaylusRevenge Maylu's Revenge]]''.
* [[StrawLoser Ace Ray]] (whose "crime" is [[TheComplainerIsAlwaysWrong complaining about Starfleet]]) and his sister Skye from ''Fanfic/MyLittleUnicorn''.
* The ''FanFic/PonyPOVSeries'' [[BadFuture Dark World Series]] has a few examples. The backstory has two symbolic examples--[[TheDragon Twilight Tragedy]] and [[HeroAntagonist Queen Cadence]] and [[WoobieDestroyerOfWorlds Traitor Dash]] and [[RebelLeader Scootaloo]]--while the present has [[TheBrute Angry Pie]] and [[CheerfulChild Apple Pie]] as a more traditional blood relation (albeit ''[[ReallySevenHundredYearsOld distantly]]'' related).
** In the Shining Armor Arc, it eventually turns out that [[spoiler: [[BigBad Makarov]] and [[RebelLeader Dima]]]] are half-brothers, with the former being the Cain.
** The former is also the Cain in a more symbolic relationship: [[spoiler: when he starts [[RewritingReality warping reality]] to wipe out his enemies and make himself the grand hero of the world, he kills all the Changelings, including Chrysalis; both Makarov and Chrysalis were created by Pandora, making them siblings of sorts.]] Of course in this case [[spoiler:Chrysalis is [[EvilVersusEvil just as much of monster as her "brother"]].]]
** On that note, [[spoiler: it's revealed that Chrysalis was created from the Shadow of Existence of the original Cadenza, while Cadence was made from her Light. This makes them "twin sisters", as Chrysalis puts it, making her the Cain to Cadence's Abel.]]
* In ''FanFic/TalesOfTheEmperasque'', Corvus and [[TheAce Roboute]] are Abel to [[DemonicPossession Fulgrim]]'s Cain, and Leman and Lion go for each other's throats the first moment they can, although which one is Cain and which is Abel is complex and twisted case.
* In ''FanFic/TheGoodTheBadAndTheDemon'' [[WesternAnimation/TeenageMutantNinjaTurtles2012 April O'Neil]] gets into this with her [[LukeIAmYourFather older sister]], [[VideoGame/SoulHackers Nemissa]] due to the tragedy caused by the latter out of jealousy of the former hanging out with Hitomi Tono.
* Fanfic/AngelOfTheBat features its main antagonist The Seraphim, who is the Cain to his older brother Joshua's Abel.

[[folder:Film - Animated]]
* The Faery Prince and the Shapeshifter in ''WesternAnimation/{{Faeries1999}}''.
* Zeus and [[EverybodyHatesHades Hades]] in ''Disney/{{Hercules}}''.
* Mufasa and Scar in ''Disney/TheLionKing'', with the unfortunate addendum that Mufasa had no idea Scar was plotting against him until it was too late. A rare case where the younger brother is the evil one.
* In an interesting if debated adaptation choice, the film ''WesternAnimation/ThePrinceOfEgypt'' made Moses the adopted brother of Rameses instead of his nephew, then played this trope to the hilt.
** The Biblical version had Moses found by Pharaoh's daughter, while ''The Prince of Egypt'' had his foster mother as Pharaoh's wife. Given [[BrotherSisterIncest marriage customs among Egyptian royalty of the time period]], the same woman could easily be the daughter of Pharaoh X and the wife of his successor, Pharaoh Y. Thus, identifying her by her relationship to a Pharaoh depends on which Pharaoh is the point of reference.
* Avatar and Blackwolf in Creator/RalphBakshi's {{WesternAnimation/Wizards}}. And how.
--> [[spoiler:"I'm glad you changed your name, you son of a bitch!"]]

[[folder:Film - Live Action]]
* Joey and Richie Cusack in ''Film/AHistoryOfViolence''.
* The vicious Red Queen in Creator/TimBurton's ''Film/AliceInWonderland'' jealously loathes her younger sister, the benevolent White Queen, because the latter is adored by the populace (and, to judge by a throwaway line toward the end of the film, was the favorite of their parents).
* A deleted scene for ''Film/AnchormanTheLegendOfRonBurgundy'' reveals that the eponymous character and [[spoiler:Wes Mantooth]] are half-brothers.
-->[[spoiler:'''Wes Mantooth:''']] I hate you Ron Burgundy! ''I hate you.''
* Angus and Henry Oldfield in ''Film/BlackSheep2007''. Angus leaves Henry to be killed by man-eating sheep, and is later [[spoiler: turned into a weresheep, at which point Henry does try to kill him as well.]]
* In ''Film/TheHungerGames'', if Gloss and Cashmere had [[spoiler: survived]] to the end of the Quarter Quell, this would have [[FridgeHorror been their fate]]. It's stated that the siblings share a close and loving relationship, so it's possible that they would've refused (like Katniss and Peeta) and preferred to die together instead of committing fratricide for a society that's already betrayed them. The Capitol citizens are at least somewhat horrified as well. Gloss and Cashmere are likely the first siblings to be pitted against each other in the same Games, and the pair visibly play this up for sympathy with hopes of the Quarter Quell being cancelled.
-->'''Caesar''': You became everyone's brother and sister. I don't know how we're going to let you go.
-->'''Gloss''': We aren't going by choice.
* Played with in Creator/WoodyAllen's ''Cassandra's Dream''.
* Lucas Strong and Kid Shaleen in the musical western ''Film/CatBallou''.
* In ''The Challenge'', ToshiroMifune plays a modern samurai master fighting his evil younger brother over ownership of "The Equals", a pair of sacred katana swords.
* In the backstory of ''Film/TheCurseOfTheMummysTomb'', Ra-Antef, the {{Mummy}} of the film, was a noble man who sought knowledge as the forthcoming Pharaoh and his brother Re was a scheming hedonist who was so jealous for his older brother's success that he organized him to be banished and later assassinated.
* ''Film/DeadInTombstone'': Red and Guerrero are half-brothers. Red has always been jealous of Guerrero, despite the fact that Guerrero has always looked out for him. Red talks the rest of gang into betraying Guerrero and fires the first shot in the fusillade that kills him.
* In ''Film/{{Desperado}}'', [[spoiler: when the Mariachi and Bucho finally face off, it turns out that they are both brothers. The Mariachi is Cesar's Manito (little brother in Spanish), while his brother is Cesar.]]
** In fact, ''Film/{{Desperado}}'' has a story very similar to ''Il Trouvatore'', where the same thing happens.
* Adam (Cain) and Fenton (Abel) Meiks in ''Film/{{Frailty}}''. Adam dutifully followed their deranged father's religious beliefs that he and his sons were hunting down demons on God's orders while they were actually murdering innocent people; Fenton always feared him and knew what they were doing was wrong. After they both left the home, Fenton has been hunting down his brother, who continued to be a serial killer. [[spoiler:And then the twist comes…]]
* In ''Film/{{Gattaca}}'', the main character Vincent was conceived without any of the advanced genetic screening that his younger brother Anton receives, and is thus subject to nearsightedness and a high likelihood of developing a heart condition. Their father clearly favors Anton throughout childhood (deciding at the last minute to ''not'' name the first-born son after himself when the potential heart condition is discovered at birth, saving that for his perfectly engineered second son). This favoritism coupled with the societal discrimination against naturally conceived "faithbirths" causes Vincent to hide his identity in order to pursue his dream of becoming an astronaut.[[spoiler:Later, the police detective who discovers Vincent's deception is revealed to be Anton, who feels insecure about how successful Vincent is despite his 'inferior' genetics (due to his determination). ]]
* In ''Film/TheGodfatherPartII'', [[spoiler:Michael Corleone]] has [[spoiler:his brother Fredo]] assassinated.
** Granted, [[spoiler:Fredo]] betrayed him first.
* A cousin example: Henry and Mark in ''Film/TheGoodSon''.
* See Michael Myers and his sister from the ''Franchise/{{Halloween}}'' movies for the slasher flick take on this.
* ''Film/JudgeDredd''. Rico Dredd, cloned from the same source as Joe, but who became corrupt, forcing Joe to sentence him to the Aspen Penal Colony. Rico returned with murderous intent.
* Franchise/MarvelCinematicUniverse:
** The main antagonist of both ''Film/{{Thor}}'' and ''Film/{{The Avengers|2012}}'' is ''Loki'', Thor's adopted brother.
** In ''Film/GuardiansOfTheGalaxy'', Gamora and Nebula have a relationship very similar to Thor and Loki's. Including being adopted siblings, the Cain having resentment issues because the Abel is the favorite of a father figure and of course Cain and Abel having very tangled love/hate relation.
* In ''Film/MortalKombatAnnihilation'', Raiden [[ShockingSwerve admits]] Shao Khan is his brother. (This is a non-canon event created specifically for the [[VideoGameMoviesSuck film]].) This is also mentioned in ''VideoGame/MortalKombatVsDCUniverse'', but again, that game is non-cannon.
* The two pharaohs in ''Film/NightAtTheMuseumBattleOfTheSmithsonian'': The elder, Kahmunrah, was utterly ruthless while the younger, Ahkmenrah, was kind and intelligent. Their parents gave the throne to Ahkmenrah, and it's implied that Kahmunrah murdered him out of jealousy.
* ''Film/PerfectCreature'' has the two vampire brother Silus and Edgar in more than just the literal sense, since they also belong to a vampire organization known as the Brotherhood.
* ''Film/PrinceOfPersiaTheSandsOfTime'': Nizam kills his brother because he wants to be king. [[spoiler: Then he tries to go back in time to kill him sooner, so he'll be king longer.]]
* With the release of ''Film/{{Prometheus}}'', [[spoiler:the relationship between the Humans and the Xenomorphs became something of this trope, as it was revealed that both species were created by ancient, humanoid creatures nicknamed Engineers, or Space Jockeys, in their bioengineering experiments. However, this trope is reinforced as the Engineers created the Xenomorphs in order to wipe out their former creation, the Humans, for reason unknown, and even when it looks like the last Engineer died by the end of ''Prometheus'', the deadly hatred the Humans and the Xenomorphs have to each other still remain active even centuries afterward.]]
* In ''Film/TheProposition'', Charlie Burns is blackmailed into killing his evil older brother Arthur, using Mikey, the younger, "simple" brother, as leverage. Ironically, their names starts with the initial, C and A. Though Charlie is the Abel and Arthur is the Cain. [[spoiler: He eventually does, but by now Mikey's already dead, and it's just because Arthur deserves to die.]]
* Luigi and Pavi Largo in ''Film/RepoTheGeneticOpera''. In this case, the hatred is definitely mutual. The existence of sister Amber is a slight complication, though… they don't dare actually try to kill each other for fear fabulously wealthy daddy Rotti will disinherit both of them.
* At the end of ''Film/{{Scanners}}'', it's revealed that [[LukeIAmYourFather Vale and Revok are brothers.]]
* The main hero and villain in ''Film/ScannersIIITheTakeover'' are each other's brother and sister, respectively. Said sister started out as a good person, but a PsychoSerum drove her into a TakeOverTheWorld-sort of villainy.
* In ''Stahlnetz: PSI'' two brothers kidnap a little girl for ransom. When the elder brother, having a family of his own, gets second thoughts about the whole thing, the younger brother beats him up, locks him with the girl and abandons both to die. [[spoiler: They are rescued by the police shortly thereafter]].
* In ''Franchise/StarWars Episode III: Film/RevengeOfTheSith'', the battle between Obi-Wan Kenobi and Anakin Skywalker is punctuated by Obi-Wan calling Anakin his brother.
** And but for a {{Retcon}}, that would have been literally the case--in the {{Novelization}} of ''ReturnOfTheJedi'', Obi-Wan calls Owen his brother.
* The ''Franchise/{{Subspecies}}'' series had its BigBad Radu and his noble [[{{Dhampyr}} half-vampire]] brother Stefan. In the first movie had [[spoiler: Stefan killing Radu in a swordfight to protect his love interest, but in the following movie, Radu is revived by his minions and, in return, kills his brother in his sleep]].
* ''Film/{{Transformers}}'': [[spoiler: At the climax of the 2007 film, Optimus calls Megatron "brother". Peter Cullen, who voices Optimus, publicly referenced the story of Cain and Abel when describing the revelation.]]
** How that works with giant robots was unexplained.
** More explicitly in the sequel, [[spoiler: the Fallen is revealed to be one of the Prime family, the original leaders of the Transformers. Optimus is either his brother or his nephew.]]
* The {{Kaiju}} film ''Film/WarOfTheGargantuas'' has Sanda and Gaira, Bigfoot-like creatures grown from remains of a giant Frankenstein's Monster, that battle to the death as a result of Sanda's opposition to Gaira's KillAllHumans attitude.
* The first half of ''Film/TheWindThatShakesTheBarley'' is the O'Donnell brothers (Creator/CillianMurphy and Padraic Delaney) fighting in the Irish Revolution together, and making enormous sacrifices. The second half is them choosing different sides in the Irish Civil War, and making even bigger ones.
* Victor is significantly more unhinged and murderous than his brother Logan in ''Film/XMenOriginsWolverine''.
* In ''Film/YearOne'', Cain and Abel are encountered early on by the main characters, who very nervously befriend Cain after the infamous act (which he violently denies) and ends up selling them into slavery. Later on, they meet Cain as a town guard of Sodom [[spoiler:and he sells them out to the king to be sacrificed.]]
* ''Film/{{Gladiator}}'': Commodus as the Cain, Maximus as the Abel. They're not related by blood, but Marcus Aurelius considered Maximus the son he should have had instead of the ambitious Commodus and nominates him as regent. Commodus also considers Maximus his non-blood brother, as both try to win Aurelius' favor and Lucilla's love. However, Commodus resorts to [[TheEvilPrince murdering his father]] and arranging to [[BrotherSisterIncest rape his sister]], while setting up Maximus' death several times. Discussed near the end:
-->'''Commodus:''' That makes us brothers, doesn't it? Then smile for me, brother! [''stabs Maximus throught the chest'']
* ''Film/{{Lockout}}'': The two brother convicts Alex (Abel) and Hydell (Cain). Both are criminals, but Hydell consistently screws up his brother's attempts at PragmaticVillainy by killing as much as he wants once the prisoners are in charge, even when it hurts their plans. [[spoiler:Hydell eventually murders Alex, thereby dooming himself.]]
* Played with in ''{{Film/Utu}}.'' Maori rebel Te Wheke clubs his little sister Kura to death for loving a white man. In turn, he is captured by the British army and executed by his big brother Wiremu.
* ''Film/SlumdogMillionaire'': Jamal and Salim's relationship eventually devolves into this in their teen years. [[spoiler: Salim eventually makes up for it in the end.]]
* ''Film/{{Spectre}}'': Franz Oberhauser[[spoiler:/Ernst Stavro Blofeld]] was James Bond's big stepbrother, but despised Bond for being a "cuckoo chick in another bird's nest" by becoming his father's favorite. Franz murdered his father and orchestrated all the tragedies in Bond's life as revenge.

[[folder:Live Action TV]]
* In ''Series/ArrestedDevelopment'' George Sr. sums Michael and Gob's relationship up thus:
-->"You and Gob are like the biblical brothers, [[MixedMetaphor Gallant and…]] [[GoofusAndGallant Goofeth!]]"
* In ''Series/BattlestarGalactica2003'', any serious conflict between the Cylons amounts to this, since all but the five originators of the race are brothers and sisters by relation.
** John murdered his brother Daniel out of jealously because his mother loved him more, polluting the models during their assembly process. [[spoiler:He later kills half his siblings for rebelling against him.]]
** Boomer and Athena's interaction also becomes increasingly hostile as Boomer feels that Athena got the life she should have had. Athena knowingly started out as a Cylon before [[HeelFaceTurn joining the humans willingly]], while Boomer believed herself to be human before having her Cylon nature forced upon her. She threatens to kill Athena's daughter Hera before Six kills her. After downloading again Boomer later [[spoiler:beats up Athena and ties her up, then forces her to watch as she makes out with Athena's human husband Helo and kidnaps her daughter for Cavil.]]
* In ''Series/{{Beetleborgs}}'', at the start of the Metallix season, the kids contact Arthur "Art" Fortune, the Stan Lee-like creator of the comic book, to revamp their superhero alter-egos. Meanwhile, the villains hook up with Lester "Les" Fortune, his jealous and psychotic brother who is serving a prison sentence, to draw new minions for them. Working for opposite sides only propels the brothers' long-time hatred for each other.
* Cesare and Juan Borgia of, well, ''Series/TheBorgias''. Cesare is the ultra-competent BadassNormal relegated to being a [[SexyPriest cardinal]] when he wants to be a soldier. In a spin, his Abel--little brother Juan--is actually not only hopelessly bad at his job as leader of the papal army, but also a jerk. The ultimate AnnoyingYoungerSibling. Unfortunately for him, Cesare [[TruthinTelevision is kind of destined to become one of the most bloodthirsty men in history]].
* Cesare and Juan of ''Series/{{Borgia}}''--an unrelated show based on the same piece of history--also use this trope. [[spoiler: Subverted, because it's revealed that Cesare ''didn't'' kill Juan. And then double subverted, because Juan'a other sibling--his unsuspected, seemingly innocent little sister Lucrezia--''did''.]]
** Juan [[spoiler: hires some assassins to kill Pedro Luis]].
* Tommy and Michael Caffee in ''Series/{{Brotherhood}}''. Tommy is a up-and-coming state politician with a young family; Michael is a senior figure in TheIrishMob with a HairTriggerTemper. As the series progresses, it turns out they're NotSoDifferent morality-wise, but they remain at odds with each other.
* ''Series/BuffyTheVampireSlayer'': Caleb, TheDragon to the final BigBad, identifies Faith as 'the Cain to Buffy's Abel' in his first appearance. Faith later concedes that jealousy over not being the Chosen One probably contributes to her tendency to be at Buffy's throat and to her going rogue in earlier seasons.
* An episode of ''Series/{{Cheers}}'' ("Ma Always Liked You Best") involved Woody bonding with Cliff's mother and Cliff becoming jealous, leading Mrs. Clavin to say she wanted to avoid "a Cain and Abel situation" and agreeing that they may "share" her.
* Horatio and Raymond Caine in ''Series/CSIMiami''. Horatio and Ray are portrayed in direct contrast to one another, with Horatio portrayed as a [[ReasonableAuthorityFigure Good Cop]] to Raymond's DirtyCop. Some episodes in the earlier seasons of the show had Horatio dealing with indiscretions Ray (who was believed to have been murdered while undercover but was actually FakingTheDead the whole time) had committed while undercover, including fathering a child with another woman, getting involved with criminal gangs and drug addiction. It was also implied that Horatio had feelings for Ray's wife Yelina, a StoryArc that never got resolved after Ray came out of hiding to reunite with Yelina and their son (but later got KilledOffForReal anyway, [[DiedInYourArmsTonight dying in Horatio's arms]]).
* J.R. and Bobby Ewing from ''Series/{{Dallas}}'' are a perfect example, with J.R. as Cain and Bobby as Abel. Though Bobby was the one that once tried to drown J.R. in Southfork's swimming pool.
* In ''Series/{{Deadwood}}'', Francis Wolcott is buying up all the goldmines around town for Hearst. In the case of one mine owned by two feuding brothers, he manipulates one brother to murder the other in order to get the sale.
* ''Series/{{Dexter}}'' Season 1 focused on Dexter and [[spoiler:Brian/The Ice Truck Killer, who was Dexter's biological brother. He served partly as an example of what Dexter would be without the Code of Harry and cleared up heaps of backstory. In a twist on the usual story Dexter killed Brian. I'm not sure which one was Cain and which was Abel…]]
** Subverted: even when siblings and death occur, it's not about sibling rivalry per se.
* The Doctor and [[EvilFormerFriend The Master]] in ''Series/DoctorWho''. It's never been confirmed on the show that the two are actual brothers, and the Doctor denies in the revived series--although the Doctor isn't the most reliable source when it comes to his past. Even if they're not biologically related, the series makes it clear that they were as close as brothers growing up, so it still counts.
** In the extended universe there is a character who is actually heavily implied to be the Doctor's older brother, namely MagnificentBastard Irving Braxiatel. It is revealed that in an alternate timeline, [[spoiler: the Doctor actually murdered him!]]
** A less extreme version occurs in [[Recap/DoctorWhoS10E2CarnivalOfMonsters "Carnival of Monsters"]]. President Zarb's policies, such as allowing aliens onto Inter Minor, are opposed by his brother Kalik, who tries to release the dangerous Drashigs into the city to force his brother to resign. Ironically he ends up getting [[HoistByHisOwnPetard eaten by the Drashigs]].
* [[ManicPixieDreamGirl Manic Pixie]] GranolaGirl Phoebe from ''Series/{{Friends}}'' was revealed to be the twin sister of RecurringCharacter Ursula on ''MadAboutYou''. On her ''Friends'' appearances, Ursula was [[{{Flanderization}} conveniently made into]] a [[TheCasanova Man-eating]] {{Jerkass}} who left Phoebe to clean up after her mistakes.
* ''Series/GameOfThrones'': Stannis Baratheon is the Cain to Renly Baratheon's Abel.
* Sean and Eric Renard of ''Series/{{Grimm}}''. At this point, it ''looks'' like Eric is Cain to his half-brother's Abel, but it can be hard to say with these two. Their problems include serious philosophical differences about how the Wesen world should work, probable rivalry for power (Eric would seem to have the edge, being the legitimate royal, while Sean is the product of an extra-marital affair on their father's part), and the question of [[spoiler:which one is the father of Adalind's child]]. Granted, neither ''knows'' about this last problem yet, but it's just waiting to be used against both of them.
* In an interesting variation, Nathan and Peter Petrelli from ''Series/{{Heroes}}'' spend the entire first season being set up as this--with Nathan, the older one, being loyal to their crazy UtopiaJustifiesTheMeans mother and a bit of a jerk to boot, and Peter, the younger one, representing all that is good and pure and idealistic--but the climax of the first season finale has [[spoiler:Nathan ultimately rejecting his mother's side and dramatically sacrificing himself to help Peter save the world. Even if he didn't actually die. Of course, many of the fans believed something like that would happen all along, and were made [[HoYay very happy]] by the mutual declarations of love that came with it…]]
** In Season 3, [[spoiler: the [[EvilCounterpart Peter vs. Sylar]] plot arc becomes this with the LukeIAmYourFather revelation that [[TangledFamilyTree Sylar is a Petrelli brother. Or not]]]]
** After the events of Volume 3's finale, [[spoiler: it looks like Peter and Nathan are heading into this direction after all.]]
* This was sometimes the case in ''Series/IDreamOfJeannie''. Jeannie's sister (also named Jeannie, also played by Barbera Eden, but with a brunette wig) was clearly evil and often tried to steal Tony for herself, but whether the two sisters were enemies depended on the situation. (Sometimes Jeannie was naive enough to trust her, but not always.)
* ''Series/KamenRiderBlack'' has adoptive siblings Minami Kotaro and Akizuki Nobuhiko kidnapped by [[NebulousEvilOrganisation the Gorgom cult]] to become their [[ThereCanBeOnlyOne competing Century Kings]]. Kotaro becomes the Abel while Nobuhiko becomes the Cain.
* KITT and KARR from ''Series/KnightRider'' could arguably be considered an A.I. version of this, with older prototype KARR the Cain to KITT's Abel.
* ''Series/KyoryuSentaiZyuranger'' has Burai's opposition to his brother Geki as much of the focus of the story--eventually however, the two are reconciled and Burai becomes the original SixthRanger.
* In ''Series/{{Lost}}'', it has been revealed that [[spoiler: Jacob and the Man in Black are brothers]].
* Bud and Kelly Bundy on ''Series/MarriedWithChildren'' are a ''very'' strange case. Very often, they are like this, willing to turn on each other and double cross each other, even breaking out into actual fist-fights at times. On the other hand, there have been times when the two have stuck up for one another, and one has defended the other sibling from another tormenor. Kelly has even gone out of her way to dole out punishments on girls who play cruel tricks on Bud. It's likely a case where it is DependingOnTheWriter, but it's a BigScrewedUpFamily in every sense of the term.
* Arthur and Morgana on ''Series/{{Merlin|2008}}''. Arthur is the Abel (the BigGood) to Morgana's Cain (the BigBad). Morgana spends most of her time plotting to bring Arthur down and has made many attempts to kill him and make him suffer. And it seems as though she doesn't even care even after learning that he's her half-brother. It's a far fall from when she actively ''defended'' him in 1x07.
* In the ''Series/{{Monk}}'' episode "Mr. Monk's Other Brother," Monk ends up taking in his half-brother, prison escapee Jack Monk, Jr. When Adrian is in session with Dr. Bell and explains his conflicts he's dealing with (he knows Jack is a fugitive, but at the same time, there are moments that he isn't unbearable to live with), Dr. Bell makes note of the Cain and Abel analogy to explain Adrian's feelings.
* Rohan and his half-demon half-brother Lugad in ''Series/TheMysticKnightsOfTirNaNog''; one of those also of the LukeIAmYourFather variety--for both sides!
* One episode of ''Series/MythQuest'' retells the story of Osiris and his brother Set. Set is jealous of Osiris' fame, wealth, and power, so he devises a plan to poison Osiris and take his place. When Alex, an IntrepidFictioneer who is taking the place of Osiris, learns of this, he calls Set "the worst brother since Cain."
* ''Series/TheOC'': Trey and Ryan Atwood, with Trey as Cain and Ryan as Abel. While the Atwood brothers' relationship, which had been tense since the beginning of the series, appeared to be improving when [[spoiler:they reunite upon Trey's release from prison]], the tension gets pushed to breaking point after Ryan discovers that [[spoiler:Trey tried to rape Marissa]]. The end result is [[spoiler:Ryan delivering a NoHoldsBarredBeatdown to Trey, before Trey gets the upper hand, and is prevented from fulfilling the Biblical version of the trope and strangling Ryan to death by Marissa shooting him in the back]].
* Dan and Keith from ''Series/OneTreeHill'' always had a rivalry because of Keith's love from Dan's ex, Karen. In season 3, Dan kills Keith because he believed Keith tried to kill him in the previous season; actually it was his then-wife, Deb. Abby who witnessed the murder left taunting messages to Dan which quoted the Cain and Abel story.
* ''Series/TheOuterLimits1995'': The season 1 episode "Blood Brothers" featured two brothers running their late father's pharmaceutical company to discover cures against various fatal diseases, with Spencer (a scientist working in a hazardous chem lab) as Abel and his big brother Michael (one of the company's directors) as Cain. Spencer wants to develop the cure for the general good of mankind, while Michael wants to limit it to the wealthy few to make more profit. Michael eventually attempts to murder Spencer and Spencer's girlfriend so he'll be the only one who knows the secret of the drug. [[spoiler:Michael then takes the drug to cure his own Huntington's and his body soon starts to decay due to the side effects, with Spencer unable to cure him.]]
* ''Series/PowerRangersNinjaStorm'' had Kanoi and Kiya Watanabe, [[spoiler:otherwise known as the team's Sensei and TheSmartGuy SixthRanger's father, and Lothor, the GenreSavvy BigBad.]] Doubled as a LukeIAmYourFather for [[spoiler:Cam,]] as he was unaware of the relation. It ends up saving [[ThoseTwoBadGuys Marah & Kapri]] in the end, because [[spoiler:Cam is a hell of a lot more merciful than Uncle Lothor!]]
** It comes up again in ''Series/PowerRangersOperationOverdrive'', this time between villains. The season has multiple {{Big Bad}}s competing with each other as well as the Rangers, and the two most prominent are brothers Moltor and Flurious.
** And years before these two series were aired, we saw a bit of this with Ryan (Cain) and Dana (Abel) in ''Series/PowerRangersLightspeedRescue'', with the former being groomed, manipulated, and taught to believe that their father loved his sister more than him. [[spoiler: He makes a HeelFaceTurn eventually]]
* Danny and Patrick Quinn from ''Series/{{Primeval}}''. Danny joined the ARC to look for his disappeared brother. He finally meets him in series 4 and is horrified to learn he's become a psychopathic killer.
* In season 7 of ''Series/{{Smallville}}'', Lex Luthor ends up creating his own Cain and Abel, [[spoiler: when it's revealed he made Grant Gabriel as a clone of his dead baby brother. When Grant discovers this, he becomes very angry and hateful of Lex. Grant tries to form a familial relationship with their father Lionel against Lex's wishes. So Lex hires a hitman to gun him down.]] Then Lex [[{{Narm}} goes outside to scream in the rain]].
** ''Smallville'' also has a version of Zor-El, Supergirl's father, who is antagonistic towards his brother Jor-El because of his love for Jor-El's wife, Lara.
** Lex and Clark Kent have been billed as being in a Cain and Abel relationship since the very first episode it seems.
*** And in Earth-2, Clark was adopted by Lionel Luthor. Didn't end well for Lex. And father is OK with that because he believes in social darwinism. However, Lionel was furious that his adoptive son hasn't killed him yet, as should be expected. After coming to "our" universe, he's soon began to miss his son and planned to revive "our" Lex. [[spoiler:Which he did.]]
** Jor-El and Zod were also similar to Clark and Lex.
** Lex ultimately ends up the Cain to yet another sibling--younger half-sister [[WellIntentionedExtremist Tess]] [[BrokenAce Mercer]], who he murders in the GrandFinale. His reasoning is that it's a version of a MercyKill so that she doesn't end up [[CardCarryingVillain like]] [[TheSociopath him]], but few people buy that--he almost definitely killed her so that she was out of his way, since at the time she had control of [=LuthorCorp=].
* In ''Series/StarTrekTheNextGeneration'', The android Data has a "brother" named Lore, which turned out [[spoiler:to contact an alien mass-killer entity and tried to let it kill everyone aboard.]]
* Subverted in ''Series/{{Supernatural}}''. This has been set up between Sam (Cain) and Dean (Abel) arguably from the beginning, with Michael even mentioning Cain and Abel directly in "The Song Remains the Same", but they keep coming back in [[ThickerThanWater brotherly love]] despite [[OurAngelsAreDifferent various]] [[DealWithTheDevil forces]] trying to set them against each other. Also, while younger brother Sam (who is the Cain to Dean's Abel) is generally [[TheHeart the kind and nice one]] ([[PsychoSerum except when]] [[LackOfEmpathy he's]] [[CameBackWrong not]]), he's also the [[TheDarkSide bad or destined "evil"]] one.
** In later seasons, this is flipped around, with Dean made analogous with Cain and Sam with Abel.
** There's also Andy (Abel) and Ansem (Cain) from the episode ''Simon Said'', a good twin and a bad twin.
** And, of course, [[ArchangelMichael Michael]] (Abel) and [[ArchangelLucifer Lucifer]] (Cain).
** Cain himself appears in season 9 with a twist. [[AdaptationalHeroism He killed his brother Abel because the latter was trading his soul to Lucifer]]. Cain gave him his place in Heaven and became the first Knight of Hell.
** Season 11 goes beyond even the show's use of the TropeNamer above, when it reveals that [[spoiler: [[UltimateEvil the Darkness]] is ''God's sister'']].
* An episode of ''Series/TalesFromTheCrypt'', appropriately titled "My Brothers Keeper", involves two conjoined twins, one of whom is a wholesome shy guy, while the other is a vain lectherous douchebag. Needless to say they don't get along.
* ''Series/TerminatorTheSarahConnorChronicles'' features an AI version of this with John Henry, who considers the newly emerging Skynet to be his "brother" since they share the same code base. Given the prevalence of Biblical metaphors in this series, it's not surprising that the Cain and Abel comparison is explicitly brought up; John Henry wonders ''which'' of the two brothers he is.
* In the Brazilian telenovela ''Series/TrailofLies, Felix Khoury always resented his adoptive little sister Paloma for taking away part of his future inherance, to the point that he left her to bleed to death after she had a complicated birth in the bathroom of a bar.
* ''Series/{{Torchwood}}'' has [[spoiler:Captain Jack and his (in this case younger) brother Gray. Gray is evil because he wants vengeance on Jack for accidentally letting go of him when fleeing from evil torturous creatures when he was little and letting him grow up being constantly tortured by them.]]
* Damon (Cain) and Stefan (Abel) Salvatore from ''TheVampireDiaries'', who've been in love with the same girl twice in the past century and a half. Currently subverted in that we've (almost) reconciled and save each other's lives more than they try to kill each other. Also Klaus (Cain) and Elijah (Abel), who parallel Damon and Stefan's relationship.
* ''Series/TheWalkingDead'' has a [[GenderFlip gender-flipped]] version of this trope with [[NiceGirl Mika]] (Abel) and [[TheSociopath Lizzie]] (Cain) Samuels, two young girls who join the main cast in the prison around season four. It started out mildly, but then along came the WhamEpisode "The Grove", in which [[spoiler: Lizzie ''kills Mika in cold blood with a knife'' after she completely loses her mind towards the end of the episode. HarmfulToMinors, indeed.]]
* The battle between twin brothers Adam and Zachary is the entire premise of ''Series/TheWanderer''.
* ''Series/WizardsOfWaverlyPlace''. Although Justin, Alex, and Max all compete to win the absolute ''Family Wizard'' title, Justin and Alex are really into it, due to the burning, brotherly hate they have for each other, that grows more and more [[IncrediblyLamePun as episodes pass by]]. It's a serious case of sibling rivalry, even though it's not clear who is Cain and who is Abel in the relationship. Justin and Alex seem to constantly switch these roles.
* Jack and Graem Bauer from ''Series/TwentyFour'', though it wasn't done nearly as well as it could have been, (but season six had [[SeasonalRot bigger problems]]).
** [[spoiler: Kate and Marie Warner]] in the second season; [[spoiler:Kate, the older one, is good, while Marie is working with the terrorists]].
** [[spoiler:Omar and Farhad Hassan]] from Season 8; [[spoiler:Omar is good, while Farhad betrays him to the extremists who don't want the peace treaty to go through]].
* Series/KamenRiderGaim establishes this as the relationship between the supporting ally Mitsuzane and the BigBad Takatora, though not in a direct confrontation. Mitsuzane hates Takatora and the empire he's building, subtly going against his back and insulting him and the lifestyle he wishes for him at every opportunity. Even as Riders, they don't have a massive conflict, since it takes Takatora a while to figure out his brother's a Rider and Mitsuzane half that time. It's only when Mitsuzane realizes ''why'' Takatora is building said empire that he joins his side… At least until [[spoiler:Takatora's allies backstab him and leave him for dead. At that point, he sides [[IFightForTheStrongestSide with whoever is stronger]], which includes [[MonsterLord the Overlords]]. Once Takatora got back and got word that Mitsuzane sided with them, ''that'''s when it gets to the brother murders brother that we all know and love, with Mitsuzane finally beating his brother… Unfortunately, they switched sides so now Takatora's the good guy and Mitsuzane's the villain.]]
* ''Series/GeneralHospital'': AJ (Cain) and Jason (Abel) Quartermaine. AJ was the alcoholic perpetual screw-up who spent the first few years of his life being shunned by his father because he mistakenly thought he was the result of his mother's adulterous affair--it's entirely likely that this is the very reason AJ was so messed up. Jason was the "golden boy" to the point of being a PuritySue--straight-A student, varsity athelete, steady girlfriend, plans to become a doctor like both of his parents (ironically, he ''was'' the result of his father's adulterous liaison, yet was never shunned by his adoptive mother as his father shunned AJ). Things came to a head with Jason jumping into a car to stop a drunken AJ from driving and AJ crashing the car and therefore killing Jason just as Cain killed Abel, albeit unintentionally (Jason recovered physically but never regained the memory of his old life, becoming an entirely new person). Despite the malevolent turn in Jason's personality, his loved ones still saw him as the old Jason and continued to treat AJ as the lesser brother.

* In ''Manhwa/WitchHunter'', the rivalry between the ''three'' princes of the Bairong Empire gets ''very'' intense, even though one of them doesn't actually want the throne… [[TheChosenOne one guess what happens]]. [[spoiler:In a heartbreaking twist, the only actual fatality so far was a ''MercyKill'' done by one brother to free the other from a GrandTheftMe inflicted on him by their ''[[ArchnemesisDad father]]''. The third sibling is furious at the killer brother for doing this, while the killer hates his surviving sibling for allowing this horrible situation to happen in the first place.]]

* Music/AvengedSevenfold (whose name was inspired by the passage of Cain and Abel) Have a song based on the passage, Titled Chapter 4.
-->I've come here to kill you,\\
won't leave until you've died\\
Murder born of vengeance,\\
I closed my brother's eyes tonight…
* ''Craig'' by Stephen Lynch, which is about Jesus' brother Craig Christ who while not TheAntichrist is a JerkJock party animal and the opposite of IncorruptiblePurePureness.
* The Finnish folk ballad ''Velisurmaaja'' (Brother Killer), where the mother inquires his son on what has happened, and the son confesses killing his brother: either for revenge from sleeping with his wife or slandering his mother.
* The Puscifer song "Rapture" deals with a sense of hatred based on this.
-->Rapture my ass\\
You better hope he takes you\\
Before I do\\
About to drop you like Cain\\
Like Cain dropped Abel
* "Buenos Tardes Amigo", by Ween, is a Mexican style ballad about a man hunting the man who killed his brother, who was adored by the villagers, the local ladies, and their mother. Of course, it was these qualities that led him to kill his brother and pin it on the poor traveller.
* "Cain's Blood" by 4 Runner is a variant, which uses Cain and Abel as symbolism for the narrator's struggle between good and evil ("Half of my blood is Cain's blood / Half of my blood is Abel's").
* Child Ballad #10, "Twa Sisters" and its myriad variations:
-->These sisters were walking on the bryn,
-->And the elder pushed the younger in.
-->"Oh sister, oh sister, oh lend me your hand,
-->And I will give you both houses and land."
-->"I'll neither give you my hand nor glove,
-->Unless you give me your true love."
* Child Ballad #13, "Edward": A mother questions her son about the blood on his shirt; though he tries to lie, he eventually admits to having killed his brother. (Or, in some versions, "a boy" not related to him.)
* Child Ballad #49, "The Two Brothers": The brothers are wrestling, one of them stabs the other. In some versions it's an accident, in most it's a murder with very unclear motives.
* Music/TheMegas portray the relationship between [[VideoGame/MegaManClassic Mega Man and Proto Man]] this way.
-->I had a name
-->My father called me Blues
-->He tore my heart from my chest
-->To give to you

[[folder:Myths & Religion]]
* The TropeNamer is in ''Literature/TheBible'' (''Literature/{{Genesis}}'', chapter 4). Cain was a farmer, Abel was a shepherd. God wants a sacrifice, so Cain brings the produce of his farm and Abel brings some sheep. God preferred Abel's offering and rebuked Cain for being mad about it whereupon Cain lured Abel into a field and killed him.
** Creator/RudyardKipling wrote a poem which claims that Abel provoked Cain by wrecking Cain's irrigation project to give the water to his cattle. (He also let them eat Cain's vegetables.) The last two lines of the poem explicitly state that the narrator thinks God's judgment on Cain was unfair.
** ''The Bible'' also gives us Esau and Jacob, although they don't end up killing each other. And later, Jacob's son Joseph and his ''ten'' older brothers (mixing it with TheUnfavorite).
** Another Biblical example, Joseph's 10 older brothers [[MadeASlave sell him into slavery]]. In an odd twist, this later saves their lives when he (as second-in-command in Egypt) saves them all from a famine.
** Genesis can be called CainAndAbel The Book with SiblingRivalry being a major recurring theme. Joseph's story is so [[CrowningMomentOfHeartwarming heartwarming]] because this trope is finally subverted and the book ends with a family forgiving each other and coming together.
** When Israel split in 2, Northern Israel is definitely Cain while Southern Judah is the Abel. Israel was wealthier and more influential but had the political stability of a game of Jenga while Judah was more spiritual and moderate. When these fight, Israel is usually the aggressor.
*** The Swedish Jonas Gardell made a point about this in his book About God, where he commented upon the fact that God showed a weird favoritism for younger sons, for no particular reason. It may have tied into favoring the humble, though, as the youngest son would inherit the least.
** The four sons of king David: Absolom, Amon, Solomon and Adonijah. Absolom killed Amon to avenge the rape of their sister Tamar and Solomon sentenced Adonijah to death because the latter had the audacity to ask the hand of their father's widow.
* Romulus and Remus, the two founders of Rome in [[Myth/ClassicalMythology Roman mythology]]. Romulus was Cain to Remus's Abel.
* Brother and sister war gods Ares and Athena would wrap entire nations up in their sibling rivalry.
* OlderThanDirt: Set and Osiris from Myth/EgyptianMythology. Set murdered his brother Osiris and took over Egypt, and later when Osiris' wife Isis tried to resurrect him, Set tore Osiris' body apart. This later caused Osiris' son to [[YouKilledMyFather seek vengeance against Set]] after he grew up.
* Karna and Arjuna from ''Literature/TheMahabharata'' of Myth/HinduMythology are these, though they don't realize it till the end of the Mahabharata (sort of a LukeIAmYourFather moment). By that time, it's too late and Karna is dead.
* Myth/NorseMythology:
** Loki betrayed Odin, who was his sworn brother, even if they had different parents.
** Hödr and Baldr, the level [[DependingOnTheWriter depends on the writer]]. The ProseEdda has Loki tricking Hödr, Saxo says it was because of a love triangle and the PoeticEdda does not state any reason.
** In ''Literature/TheSagaOfHervorAndHeidrek'', Heidrek kills his brother Angantyr (though whether it was accidentally or intentionally varies between the manuscripts).

* The "Thor vs. Loki" mission from ''VideoGame/TheAvengersZenStudios''.

[[folder:Professional Wrestling]]
* The feud between [[Wrestling/BretHart Bret]] and Wrestling/OwenHart. An exception to the "older sibling is always the evil one" rule--younger brother Owen was the {{heel}} here. Several years later, Owen and his brother-in-law Davey Boy Smith almost had a similar feud--until Bret stepped in, kicking off the New Hart Foundation angle and stable
* Wrestling/{{Edge}} and Wrestling/{{Christian}} during late 2001 to early 2002. At first they were brothers [[{{Retcon}} but they were announced as former partners]] after the feud was over.
* Several times between more responsible Wrestling/MattHardy against free spirited (and more popular) younger brother Wrestling/{{Jeff|Hardy}}, with Matt almost always being the aggressor out of envy for Jeff success. Jeff was indirectly involved in angle to cut Matt's legs off though when they both wanted a shot at Wrestling/RobVanDam.
* Wrestling/TheUndertaker and Wrestling/{{Kane}}, who alternate between hating each other and teaming up as the "Brothers of Destruction". Again, Kane is the younger brother (despite being bigger than the Undertaker), and usually the heel when they feud. In fact, Undertaker's original name was [[GeniusBonus Cain the Undertaker.]] Taker's more identified with death and lightning, Kane is identified with fire and which one set the house fire that killed their parent varies on which one is {{face}} and {{heel}}. FridgeLogic logic suggests Kane would be the more likely, given he is associated with fire and all.
* When Eddie and Wrestling/CarlitoColon feuded, Eddie was the Abel, despite being the aggressor. This is because after Carly, as he was previously known, came to the United States and started wrestling in Kentucky, he disowned his family, insisting he had no brother when Eddie made a visit to see him.
* During La Parka Jr's 2010-2011 Wrestling/{{AAA}} feud with Cibernético it was believed Cibernético had been attacking La Parka Jr's son, who was Cibernético's own godson. During a match between the two, Parka Jr's brother Taboo revealed it was him when he brought out La Parka's son to distract him.
* During the same time period in AAA, Silver King put the mask he lost to Hijo del Santo years beforehand back on, now calling himself Silver ''Cain'', arguing that he was more talented than his brother, the AAA Mega Champion Dr. Wagner Jr.
* The Wrestling/BellaTwins. In 2012 Nikki was the Abel siding with Wrestling/WWESmackDown GM Teddy Long and Brie was the Cain siding with Wrestling/WWERaw GM John Laurinaitis. Now in 2014, Brie is the Abel and Nikki is the Cain after her FaceHeelTurn at Summerslam.

[[folder:Tabletop Games]]
* Heironeous and Hextor, the gods of LawfulGood and LawfulEvil respectively in TabletopGame/DungeonsAndDragons, are brothers, and sworn enemies. Their appearances are radically different: Heironeous appears as a tall blonde human and Hextor, by contrast, is a six armed ogreish monstrosity. (Myths suggest that Hextor may have once been as handsome as his brother, and possibly even a force of Good, but was corrupted and degenerated into his current, ugly form.)
** In the TabletopGame/ForgottenRealms setting you have the twin goddesses Selûne and Shar. Having supposedly existed since the dawn of the universe and having been so close as to think of themselves as one being, they split apart on the issue of whether giving life to the barren universe would be a good idea. Selûne expresses her views on this matter by creating the Sun, which causes Shar to go AxCrazy on her and the entire universe, forcing Selûne to smack her with a HeroicSacrifice bomb. Millenia later, Selûne's dogma urges you to trust in her radiance and know that all love alive under her light shall know her blessing, while the dogma of Shar features the promotion of misery for its own sake and the direct order to destroy anything Selûne might possibly be related to, in hopes of one day tearing apart the entire universe back into the sweet nothingness it was before this whole pesky 'life' thing. Evidently, they are now ''not'' so close as to think of themselves as one being, and the family reunions must be very awkward.
** In the ''TabletopGame/{{Ravenloft}}'' setting, this situation is what doomed Strahd von Zarovich, making him a vampire and [[IronicHell the darklord of Barovia]]. When the beautiful maiden Tatyana rejected him in favor of his younger brother Sergei, Strahd developed jealousy of Sergei that eventually blossomed into hatred. He eventually [[DealWithTheDevil made a pact with some dark entity]] (Strahd claims with death itself) and on the day of Sergei and Tatyana's wedding, he murdered his brother, and then tried to pursue Tatyana, only for her to flee from him and [[DrivenToSuicide throw herself from the walls of Castle Ravenloft.]] This [[MoralEventHorizon horrid act]] cursed Strahd forever, transforming him into a vampire, making Barovia the first recorded domain of Ravenloft with him as its lord, and tormented by images of Tatyana (or women who look just like her) ever since.
* Fu Lang, the BigBad of ''TabletopGame/LegendOfTheFiveRings'', is the younger brother of the gods who founded the Empire of Rokugan. After Fu Lang was corrupted by Jigoku, he sought to kill his surviving siblings and either destroy or corrupt everything they had built.
* Urza and Mishra from ''TabletopGame/MagicTheGathering''.
** In the more recent setting of Theros, Iroas (the red/white centaur-based god of victory) and Mogis (the red/black minotaur-based god of slaughter) are brothers, and [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=380403 are known to have monumental battles.]]
* Set's vendetta against Osiris led to the creation of the TabletopGame/OldWorldOfDarkness' [[TabletopGame/MummyTheResurrection mummies]].
* ''TabletopGame/VampireTheMasquerade'''s epic plot arc involves almost a hundred books devoted to ''the'' Cain(e) and Abel. Caine is turned into the first vampire for his crime, and thus begins so much purple prose, wangst and vampires gone to the extreme that an entire retread, TabletopGame/VampireTheRequiem, was required just to put an end to Caine and his fanbase. Undeterred, entire fan cultures and anti-fan cultures sprang up around resurrecting Caine's importance to the series. Then it got resurrected for a 20th anniversary edition.
** The best part was the anticlimactic "endgame" scenario where Caine rallies all of the thousands of vampires on Earth to destroy his rebellious children, the Antediluvians. Abel's ghost appears, says he forgives him, and Caine blows it off like so much dishwater. Caine is a jerk.
** The Book of Nod contains a [[AlternativeCharacterInterpretation reinterpretation]] of the story that makes Caine seem much more sympathetic and pins most of the blame on the G-man instead.[[spoiler: After Caine's first sacrifice failed to impress (God likes blood), he reluctantly chose to sacrifice his own beloved brother instead. But rather than being impressed at the depth of Caine's devotion, God just threw a fit and cursed him instead. So he ended up short one favourite brother AND God's favour.]]
* Prevalent in ''TabletopGame/{{Warhammer 40000}}'s'' backstory, especially the primarchs: Horus killing Sanguinius, Fulgrim killing Ferrus Manus and mortally wounding Roboute Guilliman, Leman Russ coming within a hair of killing Magnus the Red, Roboute Guilliman killing Alpharius (maybe…)
** Warhammer 40,000 provides an ''extreme'' example of this trope (as it does in so many things…) is that entire ''armies'' of superhuman, genetically-engineered brothers are trying to kill each other (the Space Marines and the Chaos Space Marines).
** The Leman Russ/Magnus the Red example above is a pretty interesting example. Leman Russ and his Space Wolves were tricked by Horus into attacking the chapter, which in turn would lead to Magnus becoming the evil of the two brothers. In short, they unwittingly caused a betrayal because they were manipulated into believing it had already occurred. Leman Russ himself was simply following orders, which soon turned out to have been made by the main traitor himself.
*** Although it didn't help that Russ was all too willing to kill Magnus due to his personal dislike bordering on hatred for him as a result of his aversion to sorcery (which Magnus was a master of). Magnus, for his part, also disliked Russ, and chose to simply slaughter the attacking Space Wolves rather than attempt to reason with them.
*** Then again, probably any primarch still loyal would have shunned Magnus for going against the prohibitation of sorcery set up by the Emperor. Leman Russ and the Space Wolves in particular are very superstitious, so their dislike against Magnus was not only fueled by his ignorance to the rules set up by the Emperor, but also for the fact that they use advanced sorcery on a high level, which the Space Wolves reacted very poorly to.
* There are two ''TabletopGames/YuGiOh'' cards based off of these two, Numbers 13 and 31.

* In ''Theatre/ArsenicAndOldLace'', Mortimer Brewster is nearly killed by his AxCrazy SerialKiller brother Jonathan.
* ''Theatre/ChildrenOfEden'' does this differently; Cain accidentally kills Abel when he and Adam get into a fight and Abel [[StandingBetweenTheEnemies stands between them]].
* [[Creator/RichardWagner Wagner's]] ''Theatre/DerRingDesNibelungen'' has some pretty messed-up brothers: Alberich enslaves Mime; the earth giant Fafner kills Fasolt over the ring Alberich created; and Hagen murders his half-brother Gunther over the ring.
* Verdi's ''Il trovatore'' takes this to extremes. Ok, it takes everything to extremes.
* Golaud kills Pelléas in ''Pelléas et Mélisande'' (Maeterlinck's play; Debussy's opera)
* In ''Theatre/TheSkinOfOurTeeth'', after Cain killed his unnamed older brother, his parents had his name changed to Henry in an attempt to protect his reputation.
* In a rarer example of the younger sibling being the murderous one, ''Theatre/ThrillMe'' has a song entitled, "The Plan", which is almost entirely devoted to the variety of ways Richard has thought up to kill his brother John. [[spoiler:He doesn't, but only because Nathan points out that this trope makes for a ''really obvious'' motive.]]
* Referenced in ''Theatre/WaitingForGodot''.
* There is a ridiculous number of [[Creator/WilliamShakespeare Shakespearean]] examples for this trope:
** ''Theatre/{{Hamlet}}'''s father was murdered by his younger brother Claudius--and now Hamlet wants revenge. (The KillHimAlready element actually makes it better than it sounds.) Creator/WilliamShakespeare allegedly wrote his version of ''Hamlet'' because he wanted to improve on a previous botched stage version called the ''ur-Hamlet''. We'll never know just how bad or good the ur-Hamlet was, because no copies are known to exist.
** Orlando and Oliver in ''Theatre/AsYouLikeIt'' (older is evil)
** Duke Frederick and Duke Senior in ''As You Like It'' (younger is evil)
** Edmund and Edgar in ''Theatre/KingLear'' (younger is evil)
** Goneril/Regan and Cordelia in ''King Lear'' (older are evil)
** [[TheGloriousWarOfSisterlyRivalry Bianca and Katherine]] in ''Theatre/TheTamingOfTheShrew''
** Bassianus and Saturninus in ''Theatre/TitusAndronicus'' (older is worse, neither are prizes)
** Don Pedro and Don John in ''Theatre/MuchAdoAboutNothing'' (younger is worse, [[VillainBall for no good reason]])
** Prospero and Antonio in ''Theatre/TheTempest''
** Richard, Edward, and George in ''Theatre/RichardIII'' (youngest is evil; older two are jerks)

* Action figure super-hero Stretch Armstrong has a villainous brother named Retch Armstrong.
* From ''Franchise/{{Bionicle}}'', Mata Nui and evil Makuta Teridax, who put Mata Nui to sleep, were presented as this in legends. {{Subversion}}: Turns out the legends were lies, and while Mata Nui's really a PhysicalGod BigGood, Makuta was only one the beings living [[GeniusLoci inside him]]. DoubleSubversion: Makuta always called him "brother" (partly because he originally served on his side, partly because he saw himself as equal), and eventually usurps him, [[GrandTheftMe taking over his body]] and forcing Mata Nui to [[UpgradeVsPrototypeFight fight him using his prototype body]].

[[folder:Video Games]]
* ''VideoGame/StarWarsTheOldRepublic: The Old Republic--Knights of the Fallen Empire--“Sacrifice” Trailer'' has two brothers fighting both Republic and Imperial forces. One of them is better in combat than the other, leading to their father's disappointment…[[spoiler:After successfully killing off Republic and Imperial forces, they one brother becomes jealous of the other and attempts to kill the Father, and ends up killing his brother instead. The father is finally proud of him.]]
* ''VideoGame/AgeOfWonders'' has Meandor and his half-sister [[TheHighQueen Julia]]. [[spoiler:They got better, even becoming allies in ''Shadow Magic''.]]
* ''VideoGame/AssassinsCreedIVBlackFlag'' strongly suggests that the Assassin Opía Apito and the Templar Lucia Márquez were actually half-sisters, though neither woman seemed aware of this. The former is obviously Abel in that she was trying to protect her tribe from the Cain Lucia's attempted genocide of them for the (likely justified) death of her father at the tribe's hands.
* In ''VideoGame/BackyardSports'', Angela and Tony Delvecchio, siblings, play better on opposite teams in many games. This makes it tough to defeat one sibling using the other on a team.
* ''VideoGame/BaldursGate'' plays this trope straight in the first game, then takes it to its logical extreme in ''VideoGame/BaldursGateIIThroneOfBhaal'', wherein five of the six required bosses are siblings of the player [[spoiler:and of Imoen, who may or may not be in the party]].
* Hinted at in ''VideoGame/TheBindingOfIsaac''. One of Isaac's playable "[[PaperThinDisguise siblings]]" is the literal Cain, and a power-up is a ghost baby named Abel. Whatever Isaac/Cain does, Abel does the opposite. If [[EverybodyIsJesusInPurgatory fan theory]] is to be believed, Cain and Abel represent [[spoiler:Isaac and Maggy, as he feels guilty for hating her while she was alive, and blames himself for her death.]]
* A lot of drama in ''VideoGame/BlazBlue'' is centered on protagonists, Ragna the Bloodedge and Jin Kisaragi. Their bad blood comes mainly from Jin abandoning Ragna to die in their burned down Church home and letting their sister Saya be kidnapped when they were children. Jin's motives are mainly: 1) Since Ragna would eventually become a harbinger of destruction due to gaining an ArtifactOfDoom after said Church incident, Jin was chosen by the powers that be to be an "Antibody" to stop him. 2) His sword is an EvilWeapon and drives him to homicidal psychosis whenever he's around Ragna. Naturally, they can't stand each other, [[TeethClenchedTeamwork even when they're on the same side eventually.]]
* In ''VideoGame/{{Boktai}}'', Django later finds out [[TheRival Sabata]] is his ([[spoiler:initially]]) evil, half-brother.
* ''VideoGame/{{Borderlands}}'' gives us Jaynis and Taylor Kobb. Taylor hires you to kill his brother so he can take over Jaynistown… and then turns out to be even worse so you have to kill him too.
* The ending of ''BreathOfFireIII'' {{reveal}}s that [[spoiler:Bleu/Deis, protector of the Dragons]], is actually the [[BigBad Goddess Myria's]] sister.
* In ''VideoGame/CliveBarkersUndying'', all the Covenant children fell to the curse of the Undying King, only to be resurrected as monstrous forms of their previous selves. They're out to kill Jeremiah, the last surviving son, to complete the curse.
** There are also Bethany and Aaron, twins who utterly despised one another and were in constant rivalry. Bethany won, by [[spoiler:chaining up her brother in a dungeon accessed through her room to be eaten by rats, and removing his jaw so he couldn't scream.]]
* ''Literal'' example in the ''VideoGame/CommandAndConquer'' series: Kane is hinted to be the (immortal) Biblical Cain, and ''Renegade'' even has his Temple in Sarajevo being built around the tomb of his murdered brother Abel.
* Aku Aku and Uka Uka in the ''Franchise/CrashBandicoot'' series.
* Kasumi and Ayane of ''VideoGame/DeadOrAlive''. They were [[WeUsedToBeFriends best friends as children]], especially given Ayane's [[AllOfTheOtherReindeer status as a village pariah]]. When they discover that they are [[LukeIAmYourFather half-sisters]] and Ayane is the [[ChildByRape product of rape]], Ayane turned on Kasumi out of jealousy that the former was raised in luxury and beloved by everyone while she was scorned and hated by the same people, and is currently the one tasked with assassinating Kasumi after she left the village to pursue Raidou. Unlike most examples, however, Ayane isn't evil, just [[AntiHero Anti-Heroic]], and as of the ending of [[spoiler:''Dead or Alive 5'']], they seem to have reconciled.
* Dante and Vergil of ''VideoGame/DevilMayCry''. In the original series, it was primarily Dante and Vergil's differences in regards to which side of their nature they embraced, while in the [[VideoGame/DMCDevilMayCry new game]], it is more a question on whether the Nephilim should let humans decide their own fates (Dante) or rule over them (Vergil).
* It's quite literal in ''VideoGame/DevilSurvivor'', where [[spoiler:Naoya, the protagonist's older cousin, is revealed to be the ''original'' Cain, while the protagonist possesses Abel's essence (along with a bunch of other people, apparently). The dynamic's a little different though, as Naoya does not want to hurt the protagonist: He wants to make Abel reject God and become the king of Bel, and serves as a StealthMentor for most of the game to nudge you in that direction. He will only fight the protagonist's group in the Law and Atsuro endings, and in the latter case it's more a SecretTestOfCharacter to see if the protagonist has the will to enslave the demons.]]
* This trope is what led to [[spoiler: Fuuka]]'s murder in ''VideoGame/{{Disgaea 4| A Promise Unforgotten}}''.
* This comes up several times in ''VideoGame/DragonAgeII''. Near the end of Act I, [[spoiler:Bartrand]] succumbs to greed [[spoiler:and the lyrium idol's curse]] and tries to kill [[spoiler:Varric]] to avoid sharing the wealth. [[spoiler:Varric can either kill Bartrand as payback, kill him to save him from the lyrium idol's corruption, or put him in an asylum to care for him.]] In the "Fool's Gold" sidequest the middle brother Iwan leaves his older brother Emerys and his younger brother Merin to the darkspawn so he can claim a valuable magical sword for himself. [[spoiler:Varric will even mention that this story is awfully similar to what happened to him.]] In the endgame, if Hawke supports the Templars, he/she may end up fighting and executing [[spoiler:Bethany if she joined the Circle.]] Oddly enough, [[spoiler:Hawke's more antagonistic sibling Carver will never fight Hawke and even defends him/her as a Templar when Meredith orders him to kill Hawke.]] This can also occur with [[spoiler:Fenris]] and his sister [[spoiler:Varania]] after she [[spoiler: sells him out to his former master so that she can become a mage apprentice]]. If the player does not interfere, [[spoiler:Fenris will kill her]].
* ''VideoGame/TheElderScrollsIIIMorrowind'' gives us Vedam Dren, the noble duke of Vvardenfell, and Orvas Dren, the leader of the xenophobic criminal organization, [[TheSyndicate the Camonna Tong.]] Vedam doesn't ''want'' his brother killed, but isn't overly angry if it comes to that, while Orvas… [[spoiler: is planning to murder his brother, which you can use to blackmail him if you find the implicating letter]].
* MickeyMouse and his older [[LongLostRelative half-brother]] OswaldTheLuckyRabbit are this in ''EpicMickey''.
* ''VideoGame/ExitFate'' also contains two such siblings (in this case, twins of opposite genders): [[spoiler:Brunhild and Daniel]]. Clearly, SCF likes putting siblings at odds with each other…
* The premise of ''VideoGame/FableIII''. BigBad Logan is the tyrannical ruler of Albion you must overthrow and the son of the previous game's player character. He also happens to be your older brother. Depending on your own approach, you can potentially be better or worse than him.
* In ''[[VideoGame/FirstEncounterAssaultRecon FEAR]]'', it's explicitly canon that [[spoiler: Alma (the homicidal female ghost) is the Point Man's mother, Paxton Fettel (TheDragon) is the Point Man's brother, and the MadScientist responsible for the creation and birth of both the Point Man and Fettel was Alma's father Harlan Wade, who ruthlessly exploited his naturally born daughter's psychic abilities in an attempt to create SuperSoldiers]]. All in all they're a BigScrewedUpFamily.
* ''VideoGame/FearEffect: Retro Helix''. [[spoiler: Glas and Drew, with Glas being Abel and Drew being Cain. Rain and Mist, with Rain being Abel and Mist being Cain. Subverted in both cases, with Glas and Rain not only surviving the attempts on their lives, but end up killing off Drew and Mist]].
* This happened to no end to Cecil in ''VideoGame/FinalFantasyIV''. His best friend and comrade in arms who [[RivalTurnedEvil betrays him]] is actually 'named" Cain. (Kain in the original North American release, because I guess it was too obvious ''otherwise?''). [[spoiler: The second time it was revealed that BigBad Golbez was his ''actual'' brother.]] Of course, it was revealed in the end that [[spoiler: both were actually just being mind-controlled by the ManBehindTheMan.]]
** In the DS version, it is revealed that [[spoiler:Golbez, known way back as Theodor, was compelled by Zemus to abandon his baby brother in the woods outside Baron. If you're wondering why Cecil thinks the king as his own father up until TheReveal, now you know.]]
** [[spoiler:To be fair to Golbez, he pretty much makes up for being the Cain in the Sequel when he performs a HeroicSacrifice. Even in the CrisisCrossOver ''DissidiaFinalFantasy'' he ends up being the game's StealthMentor]].
** And to drive the point home, you can not only get Kain's Lance, but Abel's Lance in a bonus dungeon of the GBA version.
** Interestingly, ''VideoGame/DissidiaFinalFantasy'' reveals a similar relationship between [[spoiler: Chaos and ''[[VideoGame/FinalFantasyI Final Fantasy I's]]'' Warrior of Light]]. The twist being that neither knows of the connection.
* [[spoiler:[[BigBad Kuja]] and [[TheHero Zidane]]]] of ''VideoGame/FinalFantasyIX''.
* Tons of examples In ''[[VideoGame/FireEmblemJugdral Fire Emblem: Genealogy of the Holy War]]''. First the brothers of [[RebelliousPrincess RebelliousPrince]] Jamke are brutish pawns of a cult. Afterwards comes the younger brother of Briggid, [[SelfMadeOrphan who killed his own father]] [[TheEvilPrince to get the title of Duke]], Danan the evil brother of [[MadScientistsBeautifulDaughter Mad Dictators Handsome Son]] Lex. Similarily MadScientistsBeautifulDaughter Tiltyu's brother [[OverlordJr took after their father]]. Near the end the [[YoungerThanTheyLook emancipated]] but [[TheBrute super]] [[MusclesAreMeaningless strong]] brother of Johan/Johalva shows up for revenge. Finally theres Princess Julia [[spoiler:when she is not brainwashed]] is good and has the gamebreaking Naga light magic, while her twin brother Prince Julius is the inbred vassal of [[SealedEvilInACan Loptyr]] who (barring CherryTapping) needs to be killed with Naga and wields dark magic. Yes, Genealogy of the Holy War IS creepy.
*** Furthermore, only one of the pair of Johan and Johalva can be recruited, making the non-recruited one turn against his brother. And most significantly [[spoiler:Prince Seliph is also Julius's half brother]]
** In ''VideoGame/FireEmblemElibe'' there's NietzscheWannabe King Zephiel and his much gentler half-sister, Princess Guinevere… Though they did not start out that way, they used to be perfectly getting along each other, but thanks to some assassination attempt by his own father, Zephiel took up the Cain role willingly.
** ''[[VideoGame/FireEmblemTellius Path of Radiance]]'''s Mad King Ashnard probably fits. What with killing all of his other siblings and all.
** Subverted in the first game, in which the [[RedOniBlueOni token red and green cavaliers]] were actually named Cain and Abel, despite not actually being involved in any such feud. And in fact, Cain remains loyal to Marth, never gets jealous at the luckier-with-ladies Abel (who got Palla and Est having a crush on him and he married Est), and in ''Mystery of the Emblem'', Abel was instead first seen as an enemy, betraying Marth… although [[ForcedIntoEvil that was because the enemy held Est hostage]]. Also in ''VideoGame/TokyoMirageSessionsFE'', where Cain is the allied Mirage, while Abel is the antagonistic one.
* ''VideoGame/{{Galerians}}'': Rion and, uh… Cain.
* Kratos actually has several of these in ''VideoGame/GodOfWar'', [[spoiler: being a son of Zeus and all, the foremost being Ares, who tricked him into killing his wife and daughter. In only two cases, however, is the connection actually remarked upon; with Hercules, a WellDoneSonGuy who hopes to surpass Kratos, and Athena, who plays the role of ally, reluctant enemy, ally again, and finally BitchInSheepsClothing.]]
* In ''VideoGame/GrandiaII'' the main character must fight his older, more skilled, possessed brother.
* Roland and Archibald Ironfist of ''VideoGame/HeroesOfMightAndMagic''. Though, ultimately, neither brother is willing to go all the way: in their respective endings in Heroes II, Archibald gets TakenForGranite and Roland is imprisoned in the western tower (canonically, the first is what happened), and when next the two brothers meet, Archibald helps ''save'' Roland, taking him to Roland's wife despite knowing full well that she has every intention of executing him should she get the chance--Roland, in turn, intercedes on Archibald's behalf and gets the sentence down to exile.
* [[spoiler:Ros]] and [[spoiler:Lazarus]] in ''VideoGame/IMissTheSunrise''.
* ''VideoGame/JadeEmpire'': Emperor Sun Kai and your mentor Sun Li. [[spoiler: Though it turns out they're both evil, Master Li just wanted the throne for himself and trained you as a weapon against him, and he kills you once YouHaveOutlivedYourUsefulness.]]
* In ''VideoGame/KidIcarus'', Palutena and {{Medusa}}, sister goddesses of light and darkness respectively, have this type of relationship. It's not hard to guess which one is the [[DarkIsEvil evil one.]] It's subverted in that Palutena did not kill her herself, she only turned her into a monster and banished her. The angel Pit [[DidYouJustPunchOutCthulhu finished]] the [[KillTheGod job.]]
* ''VideoGame/KingdomHeartsBirthBySleep'' actually turned the relationship between [[{{Disney/Cinderella}} Cinderella]] and her evil step-sisters into this. While they were very cruel to her in the films, [[spoiler: they outright tried to [[MoralEventHorizon murder her]] out of [[ThePowerOfHate hatred]] with an Unversed in the game, which [[HoistByHisOwnPetard backfired on them spectacularly]]]].
* ''VideoGame/LastScenario'' has [[spoiler:Castor and Ethan]], respectively, including the age rule. However, it's pointed out that the younger of the two plays the role of an older sibling in many respects, which may make this a slight variation on the usual set-up.
* ''VideoGame/LeagueOfLegends'' has two pairs. Kayle and Morgana are ancient angels locked in an OrderVersusChaos war with each serving the league in hopes of gaining the power to defeat the other. Nasus tutored scholars in mystic arts while Renekton judged if they were worthy of learning them, until the evil he saw in their minds drove him into insanity and constant rage and he attacked Nasus as [[DeathSeeker the only one who could kill him]].
* There's a sidequest in the first ''Franchise/MassEffect'' game in which Nassana Dantius, an asari diplomat on the Citadel, asks you to rescue her sister, Dahlia, from slavers. [[spoiler:After you defeat the slavers, you find out that Dahlia was the ''leader'' of the slaver group. Who you killed. Nassana wanted Dahlia dead because having a slaver sister would possibly hamper her career]]. This is [[FridgeBrilliance actually kind]] [[HilariousInHindsight of funny]] due to the fact that her [[GreyDelisle voice actress]] voiced [[WesternAnimation/AvatarTheLastAirbender Azula.]]
* The Snake Brothers (okay, "Les Enfants Terribles", strictly) in the ''Franchise/MetalGear'' series. Liquid seems to enjoy the rivalry immensely. Perhaps a [[FoeYay little]] [[IncestIsRelative too]] [[ScrewYourself much]].
** It's no coincidence that [[spoiler:their mother's codename is EVA. She's explicitly linked with Eve, and not only by reference to her sons--this is her on the boys' father, who at the time went by the codename Naked Snake: "But… it was I who tempted the Snake, and got away with the forbidden fruit of knowledge."]]
* The trailers for ''VideoGame/ModernWarfare2'' explicitly invoke the murder of Abel, with Makarov talking about the blood of those killed by the United States and the UK crying out from the earth, and noting that they cannot hear the cries because they do not come from their own soil…'' [[{{Revenge}} but they will.]]''
* Bi-Han (Noob Saibot) and Kuai-Liang (Sub-Zero II) from ''Franchise/MortalKombat''.
* In ''VideoGame/{{Mother 3}}'', [[spoiler:Lucas must fight his brother Claus, who was killed, reanimated, and brainwashed into being the Pig King's loyal minion. When Claus snaps out of it, it's too late.]]
* In ''VideoGame/SagaFrontier,'' there are Blue and Rouge, twins who're told to kill the other after mastering as much magic as possible. [[spoiler: Who wins is irrelevant, since they turn out to be the same person, SplitAtBirth.]]
* The obscure PC game ''VideoGame/SanityAikensArtifact'' feature such a storyline with someone named Cain as the protagonist and the so-called foster brother Abel as the final boss.
* In ''[[VideoGame/SoulSeries SoulCalibur]]'' ''V'', Sophitia's children Patroclus and Pyrrha are driven to this [[spoiler:thanks to being egged on by Soul Calibur and Soul Edge respectively. Fortunately, the siblings are strong enough to eventually overcome the influence of both swords for each others' sake.]]
** ''Soulcalibur IV'' Sophitia becomes the Cain to Cassandra's Abel, but not willing because she has been ForcedIntoEvil.
* In ''{{VideoGame/Starsiege}}'', two mech pilot brothers are codenamed… Icehawk (the older, a cold-blooded by-the-book pilot who is loyal to the Emperor) and Phoenix (the younger, a prodigy pilot who has a knack for escaping from impossible situations and joins the Mars Rebellion). They are and are not actually related: Icehawk's real brother was critically injured in an accident and the Emperor secretly had his brain replaced by the organi-mechanical brain of his own son, as a way to continue his son's existence. Indeed, a hidden sect of people in the game world do this with their brains all the time, choosing children with life-threatening injuries and swapping brains with them while they're hospitalized.
* ''VideoGame/StreetFighterIV''. It's a definite shout out to the bible, a hero being named Abel, only the Cain is named Seth. It's made very obvious that [[spoiler:Abel is a product of S.I.N. experiments like Seth, in both his Ultra Combo(Where his eyes change color to resemble Seth's), Abel's ending, and both of their win quotes against each other in Arcade Mode]].
** According to WordOfGod, Seth was indeed originally going to be named Cain, but this was changed due to some other fighting game having a character with a similar name. It also helps that Seth is the name of Capcom's senior manager, Seth Killian, also known as "S-Kill".
** This also works for Akuma and [[spoiler:Gouken]].
* Redmond and Blutarch Mann from ''VideoGame/TeamFortress2'', to the point that not even death can stop the rivalry between them; when they're both killed by their [[LongLostRelative long-lost brother]] Gray Mann in the comic prologue to the Mann vs. Machine update, their ghosts later hire the mercs to send the other brother's corpse to Hell so they can legally be the winner of the war between them as part of the 2013 Halloween event.
* In the fashion of the ''Anime/TekkamanBlade'' example, ''VideoGame/SuperRobotWarsCompact3'' gives us sworn brothers Folka Albark (the elder, main protagonist) and Fernando Albark (the younger rival). Then there's their older brother Altis Tarl, also in the enemy's side. Subverted because Fernando and Altis are not outright evil, they're just Folka's enemies on circumstances.
** The first ''Original Generation'' game has brothers Raideisse and Elzam Branstien fighting for the first half of the story. Mostly because they happen to be on opposite sides of a war, but it also brings out a measure of animosity, mostly on Rai's part, over the death of Elzam's wife ([[SadisticChoice long story]]), whom it's suggested Rai was in love with.
** In ''VideoGame/SuperRobotWarsNEO'', Amane Inaba [[spoiler: when possessed by Larva]] is the Cain and Kakeru Inaba is the Abel.
* ''VideoGame/{{Tekken}}'' has Nina and Anna Williams.
** Kazuya Mishima and Lee Chaolan fit this trope as well since, technically [[spoiler: Lee is Heihachi's son through adoption]].
** Likewise with Kazuya and Lars, since [[spoiler:Lars is the son of Heihachi and a Swedish mistress]].
* Jacky and Sarah Bryant from ''VirtuaFighter'' had to go through this. In the first two tournaments, J6 brainwashed her and had her try to kill her brother. After she was freed from their control, her motivation for joining recent tournaments was to fight and defeat her brother, [[UnwittingPawn not knowing this is all part of J6's plot]].
* In the ''VideoGame/{{Warcraft}}'' universe, [[OurElvesAreBetter night elf]] twin brothers Illidan and Malfurion Stormrage are Cain & Abel respectively. Illidan became a demon literally due to his [[spoiler: consuming the power of the Skull of Gul'Dan]] and figuratively due to his addiction to magic.
** His jealousy over priestess Tyrande Whisperwind choosing his brother over him was actually the plot point that fixed their 10,000-year-old-feud. Events spanning throughout the third game and its expansion culminate in the brothers teaming up to save Tyrande and making up before Illidan leaves Ashenvale (for reasons not revolving around the Night Elves).
** In the {{backstory}}, [[ComicBook/{{Ashbringer}} Darion (Abel) and Renault (Cain) Mograine]] become this, fueled by their father's perceived ParentalFavoritism toward Darion. Though Renault [[SelfMadeOrphan turned his ire on Dad first]].
** In ''VideoGame/WorldOfWarcraft'', this happens with Krenna and Gorgonna in Conquest Hold. Krenna, the commander, wants to wage war on the alliance, and the more reasonable Gorgonna doesn't want it to happen. In the last quest in the chain, you fight alongside Gorgonna against Krenna and her bodyguards, killing Krenna and allowing her to take command. Despite the fact that she knew killing her was necessary, Gorgonna mourns the loss of her sister.
** During the events of Wolfheart, Jarod Shadowsong (Abel) and his sister Maiev (Cain). Near the end of the novel, they had a bloody confrontation when he had discovered she had captured and planned to kill Malfurion Stormrage; he couldn't bring himself to kill her and she fled.
** Based on a line of dialogue from the finale of the Sunwell Plateau raid, possibly Velen (Abel) and Kil'jaeden (Cain). Noteworthy in that this particular rivalry has had repercussions affecting the inhabitants of many ''planets.''
* The ridiculously [[RatedMForMoney gory]] and [[FakeDifficulty difficult]] adventure game ''{{Waxworks}}'' was built around this concept. Your family was cursed so that one of every set of twins becomes evil, and you have to go back in time using the titular waxworks building to [[SetRightWhatOnceWentWrong kill the worst of them]] and break the curse. Your own brother is incapacitated before and throughout the game, and part of your goal is to save him, but other than this, the "evil twin" aspect isn't played up much: the evil brothers of the past include Jack the Ripper, a necromancer who looks far older than his good twin, and a [[TheVirus human/fungus mutant]] who doesn't even resemble a human anymore.
* ''VideoGame/XenoGears'' has a character named Abel, and a character named Cain. Cain was (indirectly) the one who killed Abel. [[FauxSymbolism That's about where the similarities end.]]
* In ''[[VideoGame/DragonsLair Dragon's Lair II]]'', the EvilWizard Mordoc's brother is the [[SentientVehicle talking]], [[RhymesOnADime rhyming]], TimeMachine who acts as Dirk's advisor and means of chasing Mordoc through time. [[BellisariosMaxim (And no, it's never revealed how they can be brothers.)]]

[[folder:Visual Novels]]
* ''Franchise/AceAttorney:'':
** An adopted example: Franziska von Karma from ''VisualNovel/PhoenixWrightAceAttorney'' has some severe issues with her adopted "little brother" Miles Edgeworth. She's determined to outdo him in nearly everything, especially prosecuting, and is unhappy that she won't get to prosecute before he does (even though she's seven years younger than he is). Edgeworth doesn't seem to care very much, which only infuriates Franziska more.
** In ''VisualNovel/ApolloJusticeAceAttorney'', [[spoiler:Kristoph and Klavier Gavin are respectively Cain and Abel, with Kristoph being an AmoralAttorney who is responsible for Phoenix getting disbarred, and Klavier being a more moral prosecutor.]].
* Shiki and SHIKI in ''VisualNovel/{{Tsukihime}}''. Best friends, adopted siblings. Then SHIKI goes crazy because Roa possessed him plus his inversion went off. Still, turns out if they're able to meet on friendly (Kagetsu Tohya) or semi sane (Kohaku's route) terms they still actually get along quite well, and he's not really that bad a guy.
** Also from the Franchise/{{Nasuverse}} are the Aozaki sisters, Touko and Aoko, although the details aren't clear.
* ''VisualNovel/UminekoWhenTheyCry'' has ''four'' siblings in one BigScrewedUpFamily. It also subverts the usual "brothers or sisters" rivalry. [[TheDutifulSon Krauss]] is largely resented by his younger siblings, particularly [[RichBitch Eva]], who actually takes her resentment out on Krauss's wife, Natsuhi. All four of them are pretty messed up, though, due to being raised by Kinzo, and at certain points, even [[spoiler: Krauss and [[HandsomeLech Rudolf]] admit that they wish they'd been better older brothers to [[TheChewToy Rosa]]]].
* Twin brothers Leni and Seizh of ''VisualNovel/UnderTheMoon'' seem to get along fine at first, but Seizh's simmering inferiority complex regarding his more successful sibling is itching for an outlet.

[[folder:Web Comics]]
* In ''Webcomic/AmericanBarbarian'', [[http://www.ambarb.com/?p=380 Rick finds himself fighting his oldest brother]]. [[spoiler:And realizes he was party to the deaths of their other five brothers]].
* ''Webcomic/BobAndGeorge'': Bob likes to burn things and George likes ice cream. [[spoiler:Plus at the end it is revealed that this was all a plot to ensure that the hero George would kill the villain Bob if he had to.]]
** Since robots from the same creator are termed siblings, a good number of other fights.
* ''Webcomic/CtrlAltDel'''s [[JerkJock Rory]] and [[ManChild Ethan]].
* [[FauxAffablyEvil Isaac Jenner]] and his brother Gabriel from ''Demonology 101'' respectively, with a slight variation in that Issac is the younger brother whereas in most cases the older brother is portrayed as the villainous one. His hatred stems mainly from his status as the TheUnFavorite, both in the [[WellDoneSonGuy eyes of his father]] and those of [[OurDemonsAreDifferent The Powers That Be.]] [[spoiler: Isaac mellows out a bit after meeting Madeline, [[UnholyMatrimony a demon whom he falls in love with]], and eventually [[LoveRedeems gives up on trying to kill Gabriel]] as part of a deal with TheHero to save her life.]]
* ''Webcomic/DominicDeegan: Oracle for Hire'' sometimes pits Dominic and Gregory against their necromancer brother Jacob. Early on, there was an interesting twist: Dominic hated Jacob, but Gregory still wanted to believe the best of him.
** Luna's relationship with her sisters was also like this for a while, but the three eventually decided to try and at least tolerate each other after the rest of their family got themselves killed with their petty fighting.
* In ''Webcomic/{{Drowtales}}'', this tends to happen due to RoyallyScrewedUp families:
** Vy'chriel and Yaeminira. Yae was an adopted "protector twin", and TheUnfavorite. She killed Vy'chriel for the crime of refusing to tow the family line and took her name.
** The fandom now fears for Chrys and her "protector twin", Shinae. Chrys' mother actually [[GenreSavvy warns them against betraying each other]] [[http://www.drowtales.com/mainarchive.php?sid=7927 with a story about the first "protector twin"]], and what happened when the true daughter betrayed her.
** To a much lesser extent, Ariel and her older "sister" Syphile. Syphile was forced to become Ariel's Governess, despite having never been trained in childcare. After years with a BabysitterFromHell, when asked what she would most like to do, the ten-year old Ariel unsurprisingly replies "kill Syphile".
** Another example with Ariel is with her half-sister Kalki, who goes so far as to [[spoiler:stab Ariel in the hand and then chop off her arm]] they very first time they meet.
* The VillainProtagonist of ''Webcomic/FaceAllRed'' kills his older brother out of jealousy. And ''then'' things get really spooky.
* ''Webcomic/HaruSari'': Noel and Leon.
* In ''WebComic/{{Homestuck}}'', the Cherub Caliborn loathes his "sister" and split personality Calliope. He murdered her dreamself before he even started his session of Sburb. As Lord English, he is still hung up on his hatred of his sister. He destroys entire dream bubbles--tearing reality apart in the process--hunting his sister's ghost so he can finally make her DeaderThanDead. Arguably, everything bad in the entire story can be traced back to Caliborn's desire to destroy his sister and everything his sister loved.
* In ''Webcomic/ItsWalky'', [[http://www.walkypedia.com/index.php/David_Walkerton Walky]] and his separated-at-birth sister [[http://www.walkypedia.com/index.php/Sal Sal]] have fought each other at least twice, and [[http://www.itswalky.com/d/20020203.html they get pretty rough]]. Also, Beef, who was believed to be Walky's twin brother, betrays SEMME in part because of [[MissedTheCall being upstaged by his puny airhead adoptive brother]].
* ''Webcomic/LinT'': Fang and Sangwine.
* Elan and [[SdrawkcabName Nale]] from ''Webcomic/TheOrderOfTheStick''.
** And Redcloak and Right-Eye, in a more [[TearJerker heart-rending and sympathetic]] example. Redcloak didn't kill his brother over rivalry, it was because of his FatalFlaw.
** Elan ''created'' a situation like this between his puppet Banjo the Clown and another puppet Giggles the evil Clown god of slapstick. Since deities are powered by belief, the two of them are actually gods now that an entire orc tribe worships Giggles and Banjo is his equally powerful rival. Elan liked the orc high priest of Giggles' suggestion that the two were brothers.
** Nale is confused when he finds out that Roy and Julia Greenhilt actually get along. ''He thinks this trope is normal''. And so does his girlfriend.
--->'''[[HornyDevils Sabine]]:''' Some families are just… ''different''.
* In ''Webcomic/PennyArcade'', Tycho once compared his relationship with his brother to this:
-->'''Gabe''': Is that bad? Aren't you guys '''brothers''' or something?
-->'''Tycho''': You might recall that Cain and Abel were brothers.
* In ''Webcomic/{{Plume}}'', the eldest princes of Auru had this dynamic, with the twist on the story being that it was the younger who ended up killing the older.
* In ''Webcomic/SandraAndWoo'', [[http://www.sandraandwoo.com/2013/03/21/0465-birds-are-cruel-creatures/ a nature documentary showing this among birds unnerves a little sister.]]
* Cain and Abel from ''Webcomic/SerpamiaFlare''. A bit of a literal demonstration of this trope in the names; Cain has great trouble talking about his brother in Chapter Two and refers to him in past tense, while Abel expresses extreme distaste/anger at the mere suggestion that Cain may be involved with a situation at hand at the end of Chapter Two. They seem to have some past issue, though a hint in Chapter Three suggests the two brothers weren't always on bad terms.
* Oasis and Kusari in ''Webcomic/SluggyFreelance''. Oasis actually killed Kusari once, but she got better.
** Admittedly, it's unclear if their siblings in the traditional sense of the word, or if it's some weird clone/other-half-of-a-supernatural-force thing or what-have-you.
* Can we mention everyone's favorite {{Yaoi}} webcomic, ''Webcomic/{{Starfighter}}''? They're not brothers or even friends, but Cain is the codename of the violent {{Seme}} and Abel is the much nicer {{Uke}}.
* ''Webcomic/EightBitTheater'''s Black Mage once watched his own blind brother stumble around an uneven room laced with knives and tiger pits, even going so far as to push him when it seemed said brother would survive the ordeal. Of course, it would have been cruel to let him live [[EyeScream after what he did to his eyes…]]
* In ''Webcomic/BadMoonRising'', this is the dynamic between Chloe and most of her siblings, but most especially her brother Derek.

[[folder:Web Original]]
* In ''Roleplay/TheGamersAlliance'', both [[spoiler:Refan and Zarnagon]] and [[spoiler:Leraje and Ronove]] are this as they work for opposite sides in the war.
* Cortez and Mendoza Cardinal from ''TheLeetWorld''. Cortez was the leader of the Ochos Muertos terrorist group, Mendoza his second-in-command. When Cortez rejects Mendoza's plans to gain power and wealth, a furious Mendoza betrays brother, taking control of the Muertos and leaving Cortez blind. Years later, he hires the Domination Guy to kill Cortez, and when that [[DefeatMeansFriendship fails]], he concocts an elaborate plan to enter the House and finish his brother off.
** Played with when TeamDad Westheimer [[spoiler: kills Mendoza in the final challenge, saving Cortez's life. However, Cortez (who had sworn to have his revenge on his brother for blinding him) is furious, and vows to avenge Mendoza's death.]]
-->'''Westheimer''': I don't care about this feud of theirs. Probably goes back to "who did Mommy love more?"
-->'''Cortez and Mendoza''': Me!
* ''MSFHighForum'': Mel'lon and Rich.
* In one [[{{Neopets}} Neopian Times]] multi-chapter story, ''[[http://www.neopets.com/ntimes/index.phtml?section=224390&week=244 The Price of Faith,]]'' Lyth the evil, bitter [[LightIsNotGood Light Faerie]] frames her kind, sweet sister Pandora the [[DarkIsNotEvil Dark Faerie]] for stealing the Faerie Crystal from [[TheHighQueen Fyora's]] staff, breaking it into seven pieces, and scattering it across Neopia.
* In TabletopGame/NewVindicators, siblings are often at odds, its just that kind of series. Phobos and Deimos are twin brothers, and Deimos [[TheOnlyOneAllowedToDefeatYou wants to be the one who kills Phobos]], while Phobos' problems are less personal, and more because Deimos is a bad guy. In the European Academy, this pops up again, with the younger sibling being the evil one, wishing to make their older sibling suffer as much as possible, rather than outright killing them.
* The Wiki/SCPFoundation has two subjects named [[http://scp-wiki.wikidot.com/scp-073 Cain]] and [[http://scp-wiki.wikidot.com/scp-076 Able]] (along with a [[http://scp-wiki.wikidot.com/scp-336 Lilith]] who refuses to confirm or deny any relationship with them) with semi-complementary powers (Cain is an otherwise pleasant man with metal limbs who destroys any plant-based matter on contact, and anyone who hurts him receives the same injuries; Able is an eternally resurrecting and extremely deadly ImplacableMan who became a PsychoForHire for the SCP out of "boredom"). Able is still murderously angry at Cain (becoming violent at the sight of Cain's Oth, [[FridgeLogic although he shouldn't be able to know what it is if God gave it to Cain]] ''[[FridgeLogic after]]'' [[FridgeLogic Able was killed…]]
** They're both pretty much immortal. They've probably met again long before the SCP found them, and sometime after Literature/TheBible's story with them.
* Jeremy and Bran from ''Literature/ShadowOfTheTemplar''. While Jeremy still cares for Bran and wants him to reconcile with their father, Bran despises Jeremy for being a better thief than him and having stolen his father's attention from him despite being "only" a foster son. Whenever the two meet, it's always highly uncertain whether Bran will listen to Jeremy or kill him out of spite. It's even all but said that they had sexual relations in the past, which ''really'' makes their current relationship a helluva complicated one.
* StupidMarioBrothers has Merlin and Nox Decious.
* Anthony and Lyn ''Laeil'' Burbank from ''SurvivalOfTheFittest'' (although the gender tradition is bucked here
** Another example would be Josee Trembley and Remy Kim of v4, who suffer from a SiblingRivalry as a result of both siblings trying to win their mother's love as a result of both seeing themselves as TheUnfavorite. Currently somewhat played with, as Josee actually wants either one of them to live to return home, and it looks like a team-up is in the works.
* [[http://wanderers-library.wikidot.com/the-first-blood The First Blood]], a story in TheWanderersLibrary, with the Anthropomorphic Personifications of Industry and Foresight as the brothers. It's left ambiguous which is which.
* Lifty and Shifty from ''WebAnimation/HappyTreeFriends'', when Shifty decides that his brother has [[YouHaveOutlivedYourusefulness outlived his usefulness]] and tries to escape with the loot. [[KarmicDeath It never ends well]].

[[folder:Western Animation]]
* In the episode "Gonna Getcha" of ''WesternAnimation/TheAngryBeavers'', the Beaver brothers watch a movie with a Cain and Abel plot. Daggett gets absolutely loaded with ParanoiaFuel.
* In ''WesternAnimation/AvatarTheLastAirbender'', the [[RoyallyScrewedUp royal family]] of the Fire Nation exhibits this with ''two'' sets of siblings. As above, in both cases the younger sib is the [[EvilerThanThou outright sociopath]] of the two. On one of the occasions where Azula outright attempts to kill Zuko, her brother, she shouts, "I'm about to celebrate becoming an only child!"
** In season 3, Sozin and Roku are revealed to have been as close as brothers in their youth. Then Roku went away to become the Avatar, and Sozin became Fire Lord and decided that what the world really needed was to be conquered by him. They'd grown apart rather, and Roku kept shutting Sozin down flat whenever he brought these ideas up. Eventually Roku violently halted an invasion of the Earth Kingdom, which Sozin interpreted as a permanent breach of their old friendship… and therefore betrayed Roku to his death during a volcanic eruption, leaving him free to launch his world conquest.
** And in ''WesternAnimation/TheLegendOfKorra'', we have [[spoiler: Amon/Noatak and Tarrlok. Neither's exactly good, but the younger, Tarrlok, is much closer to the heroes' side by the end of things than Amon is.]] Though unlike Azula and Zuko, at the end they really loved each other.
** Book 2 has Korra's father Tonraq and his brother Unalaq, the latter going to various lengths to eliminate the former and bring Korra to his side.
* TheProfessor Amadeus Sharpe and his older brother MadScientist Wilbur Sharpe aka Dr. Scarab, from ''WesternAnimation/BionicSix''.
* Cree Lincoln and Numbuh 5 of ''WesternAnimation/CodenameKidsNextDoor''. Also, in ''WesternAnimation/OperationZERO'', [[spoiler:Numbuh Zero and Father]].
* In "The Secret Origins of WesternAnimation/DarkwingDuck", [[EvilTwin Negaduck]] is said to be Darkwing's cousin, raised by SpacePirates.
* ''WesternAnimation/DefendersOfTheEarth'' has the Phantom and his brother Kurt.
* Parodied in the ''WesternAnimation/DextersLaboratory'' episode "Dollhouse Drama".
* In the ''WesternAnimation/DiGataDefenders'' {{backstory}} Nazmul was the Cain to Adar's Abel. Nazmul became corrupted by his power and created the megalith in order to seize all the power of the di-gata stones for himself.
* A mild-example in Ed and Sarah from ''WesternAnimation/EdEddNEddy''. In TheMovie, it's revealed in that [[spoiler:Eddy had a big brother who always beat him up.]]
* The DiabolicalMastermind and BigBad Phaeton and the ProudWarriorRaceGuy and DefectorFromDecadence Marsala from ''WesternAnimation/ExoSquad''. Although both were created artificially, they were from the same brood (and one of the earliest surviving, at that), so by Terran standards, they would have been brothers.
** To add to the fun, it's implied that Phaeton's villainy is an attempt to compensate for having betrayed Marsala during the First Neosapien War fifty years ago.
* A rather lighthearted example appears in ''WesternAnimation/FostersHomeForImaginaryFriends''. The imaginary friends Imaginary Man and Nemesis (short for Nemesister) were created by a boy and his BrattyHalfPint sister respectively--the sister created Nemesis just to bug her brother and Imaginary Man. Their feud continues after the now grown up siblings adopt Imaginary Man and Nemesis for their children. Ironically enough, the brother adopts Nemesis thinking she would be the perfect friend for his daughter and the sister adopts Imaginary Man thinking he would be the perfect friend for her son.
** Terrence and Mac can be viewed this way.
* Corey and Trina from ''WesternAnimation/{{Grojband}}'', though most of the animosity comes from the latter.
* The title character from ''WesternAnimation/KingLeonardoAndHisShortSubjects'' is the Abel to Itchy's Cain.
* Twister often has this relationship with his older brother Lars in ''WesternAnimation/RocketPower''.
* Ang, the Golden Dragon and his twin sister Ying, the Shadow Dragon (whose names [[PropheticName sound suspiciously]] like [[SiblingYinYang Yang and Yin]]) in ''LegendOfTheDragon'', at least until [[spoiler:Ying's HeelFaceTurn]].
* ''Franchise/MastersOfTheUniverse'': [[spoiler:Big Bad Skeletor was supposed to secretly have once been Keldor, the brother of King Randor (and thus Prince Adam/He-Man's ''uncle''). This was never officially revealed in any canon but has been confirmed as the intended outcome of the original minicomics that had already begun to {{anvilicious}}lly hint at it when the toyline was axed. Skeletor's past as Keldor was depicted in ''WesternAnimation/HeManAndTheMastersOfTheUniverse2002'' and the backstory of he and Randor being half-brothers was discussed by the writers on a DVD commentary as being an additional reason for their more specific & personal animosity in that version.]]
* Megaman and Protoman are this in the Ruby-Spears ''WesternAnimation/MegaMan'' cartoon.
* Princess Luna and Celestia form a rather complicated example in ''WesternAnimation/MyLittlePonyFriendshipIsMagic''. Luna got corrupted by an outside influence and when that was gone Celestia immediately offered to return her to power.
** Also, in the episode, [[Recap/MyLittlePonyFriendshipIsMagicS3E4OneBadApple "One Bad Apple"]], Babs Seed, who is the cousin of Apple Bloom, bullies the Cutie Mark Crusaders after she joins Diamond Tiara and Silver Spoon. [[spoiler: However, when it turns out that she only did that out of fear of being bullied herself, she and the CMC make amends.]]
** The season 4 finale backstory has [[BigBad Tirek]] and Scorpan (originally from the G1 pilot episode ''[[WesternAnimation/MyLittlePonyTVSpecials Rescue at Midnight Castle]]'') [[RelatedInTheAdaptation are reimagined as two brothers]]. They aim to steal all the magic in Equestria until Scorpan [[ThePowerOfFriendship makes friends with the ponies]] and [[HeelFaceTurn turns against Tirek]].
* Sensei Wu and Lord Garmadon in ''Franchise/{{Ninjago}}'', between Garmadon getting bit by the Great Devourer up until he's returned to normal following the first defeat of The Overlord.
* ''WesternAnimation/OverTheGardenWall'': Adelaide (Cain) and [[spoiler:Auntie Whispers]] (Able)
* Spheros and Betrayus from ''WesternAnimation/PacManAndTheGhostlyAdventures''.
* The relationship between Mojo Jojo and the girls in ''WesternAnimation/ThePowerpuffGirls'' could easily be seen this way, especially after it's revealed that [[spoiler: it was Mojo who caused the accidental addition of Chemical X into the perfect girl mixture]]. Interestingly enough, it's [[InvertedTrope he]] who has a VillainousBreakdown when [[LukeIAmYourFather the truth]] is [[TheReveal revealed…]]
* ''WesternAnimation/ReBoot'''s principal villains, Megabyte and Hexadecimal, are brother and sister, yet they are always trying to kill each other. When an incredulous Bob asks why, Hexadecimal casually explains that it's just "sibling rivalry."
** Thanks to a {{Retcon}}, Megabyte and Matrix fit this too. Matrix's dad, Wellman Matrix, is responsible for the "birth" of Megabyte. Megabyte even calls the nullified Wellman "father" so this makes Megabyte and Matrix brothers. Good thing Matrix doesn't know this since he has a problem with viruses.
* ''WesternAnimation/RobotAndMonster'' has Robot and his {{Jerkass}} older brother Gart, who considers himself the AlwaysSomeoneBetter to Robot and will do anything to run afoul of him, such as buying the main duo's apartment and using his power to wildly lower and raise the temperature or creating a [[{{Calvinball}} Pole-O]] team to go up against his, then using a blatantly false sob story to garner sympathy. Over the show's [[ShortRunners single season]], Gart got hit by LaserGuidedKarma at least twice.
* In ''WesternAnimation/ShadowRaiders'', Femur arranged for his brother to be locked away in the prison planet, a hellhole where the Cluster's worst war criminals were sent to, where he was subjected to horrific tortures and expected not to survive. Considering Femur had to bribe the soldiers that were dragging him away so he wouldn't be executed, Sternum had it coming for A: trying it and B: not using more loyal guards. And from what we later see, while Sternum is less ObviouslyEvil, he isn't actually any better.
* ''WesternAnimation/SouthPark'':
** Eric Cartman and [[spoiler:Scott Tenorman]].
** Lemmiwinks and Wikileaks in "Bass to Mouth". In this case, it's the good brother killing the evil brother.
* In ''WesternAnimation/SupermanTheAnimatedSeries'', Weather Wizard tries to kill his younger brother when [[NotWhatISignedOnFor he backs out of his mass-murdering plan.]]
* Jeera and Zariah from ''VideoGame/TakAndThePowerOfJuju''.
* ''WesternAnimation/TeenageMutantNinjaTurtles'':
** In the [[WesternAnimation/TeenageMutantNinjaTurtles2003' 1987 series]], Shredder's younger brother, Lt. Kazuo Saki, is a member of the Tokyo Metropolitan Police Department; the two brothers ''despise'' each other, Kazuo rather embarrassed to have such a man as a sibling. (Note that in most continuities, "Saki" is actually Shredder's given name, his family name being "Oroku"--placed before the given name, as is done in Japan--making this version something of an error compared to other continuities.)
** In the [[WesternAnimation/TeenageMutantNinjaTurtles2003 2003 series]], adoptive brothers Hamato Yoshi and Yukio Mashimi become this when Mashimi, in a fit of jealousy, kills fellow adoptee and love triangle member Tang Shen. Afterwards, Yoshi kills Mashimi in revenge. (This is an adaptation of the story of Hamato Yoshi and Oroku Nagi from the original Turtles story, which led to quite the CycleOfRevenge when Nagi's younger brother Oroku Saki, who would later become the Shredder, murdered both Yoshi and Shen in vengeance for Yoshi killing Nagi.)
* Starfire and Blackfire of ''WesternAnimation/TeenTitans'', who still look like a parallel of Queens Elizabeth and Mary Tudor, even though Glen Murakami admits that they watered down the ''much'' more intense rivalry of [[ComicBook/TeenTitans the original comics]] into a more kid-friendly, "''Series/IDreamOfJeannie''/''Series/{{Bewitched}}'' kind of way." If you're even slightly familiar with the comics, you'll know what he's [[http://www.titanstower.com/assets/animated/behind%20scenes/comicbookpics/panels/blackfirebattle.jpg talking about]].
* In the ''WesternAnimation/ThunderCats2011'' episode "Between Brothers," BigBad Mumm-Ra hopes to [[InvokedTrope invoke]] this trope when {{Sibling Rival|ry}}s Lion-O and Tygra travel to the Astral Plane, where they witness [[FightingDownMemoryLane a scene from their youth]] that drives them to SwordFight, Tygra using an astral copy of Lion-O's own Sword of Omens.
* ''WesternAnimation/TotalDrama'' has its first sibling duo in ''Pahkitew Island'' with Amy (Cain) and Samey (Able).
* ''Franchise/{{Transformers}}'' has [[HumongousMecha Planet-sized]], TransformingMecha (that turn ''into'' [[ThatsNoMoon planets]]) {{Physical God}}s Primus and Unicron. Unicron is the BigBad GodOfEvil OmnicidalManiac seeking to destroy ''everything'' that isn't him. Primus is the BigGood who is [[GunPorn completely]] [[MoreDakka loaded with]] {{BFG}}s and {{Wave Motion Gun}}s seeking to thwart his brother. However, his trump card isn't any of that weaponry--it's ''the Transformers themselves.'' Unfortunately, they'd rather spend their time fighting each other.
* Kitty and her evil twin sister, Katty, from ''WesternAnimation/TUFFPuppy''.
* Played with by ''WesternAnimation/TheVentureBrothers'' where Thaddeus "Rusty" Venture eats his twin brother Jonas Venture, Jr while they were still fetuses. Jonas survives and later escapes, and attacks Thaddeus but gives up because he can't kill his own pathetic brother. Jonas finding his true calling as a heroic man of science quickly becomes a success financially, and with the ladies. It's basically implied that both would be successful if Thaddeus became a super villain, and arched his good brother.
** As the series progresses it's hard to say who is Cain and who is Abel--Jonas Jr. is certainly living up to their father's legend, but we start to see that Jonas Sr. had a pretty sleazy side.
* The Miser Brothers, Snow Miser and Heat Miser from ''TheYearWithoutASantaClaus'', might be one of the best examples of this trope.
* IvanhoeTheKingsKnight, as tradition dictates, features this between King Richard and Prince John.

[[folder:Real Life]]
* Baby sharks developing in the womb will fight and eat each other before they are born. Only two sharks end up being born, and that's only because there are two separate wombs.
* Invoked by the crown inheritance of the AssyrianEmpire. As often case in polygamist cultures, the heir of the throne did not follow the primogeniture but rather ''every'' son of the king was a valid claimant. The usual way of arranging the inheritance was an ''all-out murder roulette'' where the sons murdered each other until only one was left. Although this practice was intended to guarantee that the ''ablest'' of the heirs would inherit the throne, it also meant that the Empire fell into anarchy and civil war until the new king had established himself. It eventually led into the collapse of the Empire.
* Pagan Min, the ninth king of the Konbaung Dynasty of Burma. When his father Tharrawaddy died in 1846, he was in line for the throne but his brothers opposed him. To ensure his right to the throne had no detractors, Pagan had his brothers killed.
* The Banquet of Nyköping 1317. The Swedish king Birger had invited his younger brothers, dukes Valdemar and Erik, to Castle Nyköping to feast at Christmas. After everyone had gotten drunk, king Birger imprisoned his brothers, put them in the [[ThrownDownAWell oubliette]] of the castle and (so tradition says) threw the key into the nearby river. The dukes died from starvation. A large medieval key was found near the castle in 1847.
* The end of the Kingdom of Judah, as described in the Book of Kings and Chronicles in TheBible.
* Though it will never be proven, it's extremely likely that Cesare Borgia (son of Pope Alexander VI and then-Cardinal of Valencia) murdered or ordered the murder of his younger brother, Giovanni (Juan) Borgia, the Duke of Gandia. Juan was a hopelessly inept military commander, favored by his father; Cesare hated him and wanted his position. Being a [[MagnificentBastard magnificent bastard in more ways than one]] Cesare actually excelled at the job until his father died and ran out of funds.
* Similarly, chicks of several species birds of prey are known to murder their siblings while in nest.
** Not just birds of prey either; seabirds like pelicans have been known to do this. Usually, the older, stronger sibling attacks a smaller weaker one and often ends up shoving it out of the nest. See an example, in all its [[NightmareFuel horrifying]] glory, [[http://www.arkive.org/brown-pelican/pelecanus-occidentalis/video-17b.html here]].
* An interesting historical example is the murder of King Erik IV of Denmark by his brother, Abel. Chroniclers called the murderer "Abel by name, Cain by deeds."
* In 16th century Sweden, king Erik XIV starts behaving like he is insane and is deposed and imprisoned by his younger brother Johan after an insurrection. Johan makes himself king, while Erik's son and heir to the throne Erik Jr disappears abroad. Later king Johan has Erik Sr poisoned to death.
* Byzantine Emperor Isaakios II adored his brother Alexios and gave him many honors. Alexios repaid him by staging a coup, putting out his brother's eyes, imprisoning him, and crowning himself emperor as Alexios III. Isaakios' teenage son managed to escape his uncle's tyranny and showed back up on his doorstep with an army: [[UsefulNotes/TheCrusades The Fourth Crusade]]. Things went FromBadToWorse shortly thereafter, and Constantinople passed out of Byzantine hands for almost sixty years.
* Following the death of John VI of Portugal, his oldest son Pedro (then Emperor of Brazil) briefly succeeded to the throne. After abdicating in favor of his infant daughter Maria, Pedro's younger brother Miguel declared himself King, which led to the Portuguese Civil War (alternatively known as the War of the Two Brothers.) Six years later, Maria was returned to the throne, Miguel and his family were forced into exile, and Pedro died shortly after achieving victory.
* Invoked by Marie-Antoinette against her brother-in-law, Comte de Provence and future Louis XVIII, who stood idle as his brother Louis XVI was being murdered. According to José Cabanis' biography of the third brother, Charles X, Marie-Antoinette actually referred to the Comte de Provence as ''Caïn''.
* The Minamoto brothers, Yoritomo and Yoshitsune, in feudal Japan.
* The Mughal dynasty had a lot of these. A prominent example is the murder of Prince Dara Shikoh, the King's oldest and favorite by Aurangazeb, a younger son.
* The Ptolemys of Egypt were great proponents of this. A rather famous one Cleopatra, was a big fan.
* The death of a Sultan of the Ottoman Empire regularly resulted in his male sons eliminating each other until only one legitimate heir was left. This was a result of Muslim marriage customs and inheritance law, which established that any son who could claim patrilineal descent (regardless if the mother was one of the Sultan's wives, concubines or slaves) had a legitimate claim to the throne. The practice was eventually discredited, with exile or imprisonment (in luxury conditions) becoming the preferred option for dealing with rival claimants.
* One of the greatest Emperor of Tang Dynasty, Emperor Tang Taizong is this trope. In an infamous incident known as the ''Xuánwǔmén zhī biàn'' (the [[http://en.wikipedia.org/wiki/Xuanwu_Gate_Incident Xuanwu Gate Incident]]), he ambushed his older brother Li Jiancheng (the crown prince) and his younger brother Li Yuanji. He killed his older brother personally, forced his father to make him crown prince only to make it proper for his father to surrender his throne to him just two months later.
** Oh ya, he also killed the sons of both Li Jiancheng and Li Yuanji, and made Li Yuanji's wife his concubine. That's just some badassery.
** And it's true that he's a noble Emperor.
** Li Jiancheng and Li Yuanji were also plotting against Li Shimin (brother number two). Li Jiancheng was jealous of his second brother because Li Shimin was more capable in almost every respect, and may have feared losing his crown prince position to him as a result. He recruited his third brother who was similarly jealous, and the two of them were in fact preparing an ambush/attack of their own at the very moment they themselves were ambushed. Or so it has been recorded. (History tending to be written by winners who become emperors…)
* Played definitely straight in the UsefulNotes/WarsOfTheRoses in 15th century England. It effectively meant the extinction of the Plantagenet dynasty and whole family line.
** The most specific example is George, Duke of Clarence. He is largely overlooked, with [[RichardOfGloucester Richard]] being seen as the treacherous brother of Edward IV. However Clarence tried rebelling against Edward by claiming they were illegitimate meaning he was the rightful King, then helped a rebellion against Edward by the previous royal family, before switched sides again. Considering this, it isn't surprising Edward didn't trust him. Clarence continued to cause trouble for Edward, apparently thinking he wasn't getting enough influence, and was finally executed. Ironically enough, despite the Play "Richard III" having Richard be responsible for George's death, the earliest sources of this event claim one of the reasons Richard may have been opposed to the Woodvilles was because he blamed them for this.
* William the Conqueror's children. Henry (who may have [that is: almost certainly]) had his other brother William Rufus murdered to gain the throne of England, staged a coup in Normandy against his eldest brother Robert, while the other was on crusade, and later imprisoned him.