''My Sister's Keeper'' is a 2003 novel by Creator/JodiPicoult. Anna Fitzgerald has gone through countless surgeries, transfusions and shots by the age of thirteen. Is she sick? No. She's doing it for her older sister Kate, who has suffered from severe leukemia since the age of three. Anna was born to be a perfect match for Kate. Kate now needs a kidney and Anna decides she's had enough. So she sues her parents for medical emancipation. This book has a high TearJerker warning, and is the [[http://www.ala.org/ala/issuesadvocacy/banned/frequentlychallenged/21stcenturychallenged/2009/index.cfm 7th most challenged book in schools and libraries for 2009]]. Made into a [[TheFilmOfTheBook movie]] starring Creator/AbigailBreslin as Anna and Sofia Vassilieva as Kate in June 2009.
!!This book contains examples of:
* AbusiveParents: Sara is the emotional abuse type, though she isn't doing it because she hates Anna; rather, it's because her single-minded devotion to Kate blinds her to the needs of her other children. When Anna was five, Kate needed bone marrow from her so Sara had doctors restrain Anna while they extracted the bone marrow. Whenever Anna questions her, Sara always blackmails her saying "why won't you help your sister?" One of Kate's messages to Anna in the movie is "I'm sorry I let them hurt you", make of that what you will.
* TheAlcoholic: [[spoiler: Brian after Anna's death, although he gets better.]]
* BittersweetEnding: [[spoiler: Anna wins the lawsuit. On her way to the hospital to see Kate she is in a car accident that leaves her brain dead. Alexander decides her kidney should be donated to Kate which saves Kate's life. So Sara gets what she wanted - Kate gets to live - but it comes at the cost of her younger daughter's life, and there are no guarantees Kate will stay in remission.]]
* DiabolusExMachina: Ohhhhhhhhh yeah.
* DebateAndSwitch:[[spoiler:Due to the ShockingSwerve, the moral dilemma is averted.]]
* DesignerBabies: Anna is probably a more realistic example of this trope.
* DownerEnding: [[spoiler: The book ends with [[DebateAndSwitch Anna dying in a car crash]] and her organs being harvested for Kate, while Sara gets her way yet again. The film changed this into a BittersweetEnding/ EarnYourHappyEnding.]]
* ExpositoryHairstyleChange: In the present Sara's hair is long and straight. When it shows Kate, Anna and Jesse as children it is longer and curly. In the ending scenes it is cut short.
* HairReboot: Sara shaves her head to show support for Kate though the movie keeps changing timelines so two scenes later her hair is back to its original length.
* HeelFaceTurn: Campbell.
* [[spoiler:TheHeroDies: Anna herself in the novel, while Kate dies in the movie.]]
* HighSchoolSweethearts: Campbell and Julia.
* IllGirl: Kate
* ItsAllAboutMe: Like many of Picoult's fictional mothers, Sara has this trait. For most of the book, she believes that Anna has filed the lawsuit to ''annoy'' her. She's genuinely surprised when Kate reveals how she actually feels, and her first thought when she is confronted with her daughter's fate -- [[spoiler: Anna's brain-dead, organ-harvested body]] is not "my poor baby" but "what do you call a parent [[spoiler:who's lost a child?]]
* KnightTemplarParent: Sara, who both creates and blights Anna's life in order to save Kate, while dismissing anyone who isn't of any use in the pursuit of that goal. Including ''her own son''.
* MiddleChildSyndrome: Inverted; Kate is the middle child of the family, and gets all of the attention because of her cancer.
* ParentalFavoritism: There are countless examples. The mother, Sara, mainly cares about Kate and Kate only. She only cares about Anna because she can help Kate. Here are the more depressing examples.
** While pregnant with Anna, she hadn't even thought of a name, she was more happy with the thought that the baby would help Kate. It is only until the book progresses that Sara does learn to love the real Anna more.
** Kate needs more lymphocytes from Anna. The appointment falls during her friend's birthday party and Anna is allowed to stay for half of the party. As Sara is taking Anna to the car, she asks why she had to leave. Sara is so angry because "[her] sister is more important than cake and ice cream", that she tells Anna to stop acting like a five year old. Anna was five at the time.
** The oldest son Jesse is neglected after it is found out he is not a genetic match for Kate. Sara finds it hard to feel sorry when he, a 6 year old, gets his blood tested to see if he is a match for Kate. As a result he becomes a chain smoker and a PyroManiac.
*** Another example with Jesse: at one point Sara is too depressed over Kate to take Jesse to shop for new cleats like she'd promised, and tells him they won't be going. Jesse gets upset and points out that she isn't even doing anything, and Sara screams at him until he runs upstairs upset. When Sara later goes up to apologize to him, she discovers that Jesse has ''used a fork to pull out his braces'', and he says to her, "Now you never have to take me anywhere."
* PyroManiac: Jesse.
* RunningGag: Campbell never giving anyone a straight answer once they ask what his service dog is for, since he's not blind. [[spoiler:But he ''is'' epileptic.]]
* ScholarshipStudent: Julia at the Wheeler School where she and Campbell met.
* ShootTheShaggyDog: In the original novel, at least. Anna's battle for medical emancipation is proven pointless when she [[spoiler:dies in a car accident and both her kidneys are harvested for her older sister.]]
* ThirdLineSomeWaiting: Campbell (Anna's lawyer) and Julia's relationship. Julia is removed in the movie.
* TitleDrop: When Julia turns up at the Fitzgeralds' and asks Jesse where Anna is, he replies "Am I my sister's keeper?"
* TheUnfavorite: Jesse, and to a lesser extent, Anna. See ParentalFavoritism above.
* UselessBystanderParent: Brian. While not happy with Anna's WalkingTransplant status, he pretty much lets Sara get her way all the time, resulting in this trope.
* WeNamedTheMonkeyJack: Campbell's dog, Judge.
* WalkingTransplant: Anna