* ''VideoGame/{{Bully}}''. Yeah, let's all go pick on the shaven-headed SociopathicHero who's already proven capable of beating down TheIncredibleHulk in a school uniform.
** And after he kicks our asses, [[BullyingADragon LET'S DO IT AGAIN!]]
*** Jimmy can choose to indulge in acts of cruelty as well. These can range from the mundane (wedgies and shoves) to the downright brutal (beating fellow students with baseball bats or repeatedly stomping on a fallen foe's head while the victim moans in pain). Taken to extremes when Jimmy chooses to torment adults, though the peril of bullying adults is significantly greater than picking on a nerd.
* The Red Crayon Aristocrats from ''RuleOfRose''.
** To clarify: The game stars a group of unbelievably monstrous girls (The aforementioned "Red Crayon Aristocrats") who torment the main character, forcing her to do their bidding and then rebuke her efforts every time. Then, [[spoiler: the one girl who was nice to you]] turns out to [[FalseFriend be the one behind it all along]]. Do note however, that from the perspective this is all told from, some of the girls' attitudes and behaviors may be a result of UnreliableNarrator.
* Once upon a time, before ''TheSuffering'' began, three Puritan children decided to start a WitchHunt just for fun. Eleven people were [[BurnTheWitch burned at the stake]], and three little girls were remade as [[UndeadChild immortal monsters]] by [[GeniusLoci the land itself]].
* ''OverlordII'' opens up with the son of the previous Overlord as a child being pelted with snowballs by some kids in his village. This is of course a case of BullyingADragon when the "Witch-Boy" returns to fulfill his duties as an EvilOverlord.
* Alessa's schoolmates in the first ''SilentHill'' game and the movie, another case of BullyingADragon.
* [[{{Jerkass}} Silver]], TheRival from ''VideoGame/PokemonGoldAndSilver'' and the remakes, thanks to a FreudianExcuse revealed in the latter. [[CharacterDevelopment He gets better.]]
* Mewt Randell, a boy who is picked on by bullies, becomes overlord of his own fantasy world very early on in ''FinalFantasyTacticsAdvance''.
** Ritz also gets some bullying for her white hair. She's more confident than Mewt, but the events after Mission 14 indicate that she's taking it harder than she lets on.
* ''VideoGame/{{Fallout 3}}''. Several of the kids in [[spoiler: [[ThereAreNoAdults Lamplight Caverns]]]].
** Butch, though you can retaliate easily enough against him.
* ''VideoGame/GrandTheftAutoViceCity'' has Lance Vance, who got picked on in school due to his UnfortunateName.
-->'''Tommy Vercetti:''' Vance? Your name's Lance Vance?
-->'''Lance Vance:''' Hey, I got enough of that at school.
-->'''Tommy Vercetti:''' Lance Vance. Poor bastard.
* ''InazumaEleven 3: Sekai e no Chousen: Bomber'' starts by showing TheRival Rococo being bullied by bigger, stronger kids in his childhood.
* [[spoiler:Iris]], from {{Rosenkreuzstilette}}. [[spoiler:She disguises herself as an innocent girl to hide that from everybody.]]
* In ''KatawaShoujo'', Hanako, whose body was severely scarred in a house fire that killed both her parents, was bullied by her classmates for her appearance when she returned to school, including several of her former friends.
* ''VideoGame/MetalGearRisingRevengeance'': Sundowner is a firm believer in this, boasting that kids are malleable and can be easily manipulated into becoming malevolent {{Child Soldier}}s and later boasts about how [[PsychopathicManchild he's very in-touch with his inner child]]. Raiden [[BerserkButton does]] ''[[PapaWolf not]]'' [[RoaringRampageOfRevenge approve]].
* The Skull Kid in ''VideoGame/TheLegendOfZeldaMajorasMask''. The carnage that he invokes is fundamentally caused by his innocent inability to understand adult relationships and responsibilities, and a childlike egocentricity that makes him regard inattention toward himself as a deliberate insult. Thanks to SanitySlippage from the Mask, he decides the appropriate response is to curse everyone he meets and set up the destruction of the world.
** The Bombers can occasionally fit this as well. While their job is helping out others in town, Jim is plenty rude if Link talks to him while he's playing games. The other kids all refuse to let Deku Link officially join their club because [[FantasticRacism he's not human]]. Granted this mindset was implied to to have sprung from their last non-human member (the Skullkid) causing trouble instead of helping others, thus making them reluctant to take another chance, but still.
* Pretty much the entire school goes feral in ''VideoGame/OurDarkerPurpose'' when all the teachers disappear. Most notable are Regan and Goneril, who arrange an outright massacre of weak, quiet students.
* In ''VideoGame/DeadCase'', there is a group of children who torment a little girl repeatedly. The first time the protagonist comes across them, he must scare them away. [[spoiler:Later, the school ghost scares them away and protects the girl.]]