Dedicated to villains who have completely lost their shit.

* DragonBallZ: [[http://images.wikia.com/dragonball/images/4/4a/FriezaFinalFormNV..png I have an empire and No one can beat me]] que to SJ Goku's fight finale with [[http://i251.photobucket.com/albums/gg307/NJ_Ninja/Frieza.png No more empire and beaten by a monkey]]
** Cell [[http://images.wikia.com/dragonball/images/0/0d/CellPerfectNVVsGoku.png before]] fighting SSJ 2 Gohan [[http://images.wikia.com/dragonball/images/5/55/CellPerfectLosingNV.png after]] fighting SSJ 2 Gohan.
* Manga/{{Bleach}}: [[http://i251.photobucket.com/albums/gg307/NJ_Ninja/Barragan.png His words say it all.]]
** Also Aizen went from [[http://images.wikia.com/bleach/en/images/a/ab/Aizen.png this]] to [[http://images3.wikia.nocookie.net/__cb20110216042948/bleach/en/images/0/0a/Aizen_Break-Down_Poster.png this]] after a long fight.
* [[Franchise/ResidentEvil Albert Wesker]] [[http://image.gamespotcdn.net/gamespot/images/2010/216/imagegallery01_albert_wesker_03423_640screen.jpg before he snaps.]] Albert Wesker [[http://fc00.deviantart.net/fs45/f/2009/109/4/a/Demotivational__Albert_Wesker_by_Nintendoart.png after he snaps.]]
* ReturnToOz The Nome King goes from [[http://content7.flixster.com/question/53/60/57/5360577_std.jpg this]] to [[http://farm6.staticflickr.com/5290/5234982586_d0f1891814_z.jpg this]] once he realizes what Dorothy is doing.
* [[ArchieSonic Sonic The Hedgehog:]] Dr Eggman [[http://images.wikia.com/archiesonic/images/1/1b/Eggman_upgrade.jpg before,]] [[http://images.wikia.com/archiesonic/images/2/2d/Eggman_madness01.png during]] and [[http://images.wikia.com/archiesonic/images/8/87/Warlord-Doctor_Julian_Ivo_Eggman_Mach_Two.JPG after]] his descent into madness.
* WesternAnimation/AvatarTheLastAirbender gives us the most terrifyingly competent sociopathic fourteen-year-old you will ever meet in [[http://images4.fanpop.com/image/photos/21200000/princess-azula-azula-21219333-720-480.png Princess Azula]]. The finale gives us her [[http://images1.wikia.nocookie.net/__cb20090405200129/avatar/images/6/63/Angry_Azula_yells.png complete]] [[http://saimaisama.files.wordpress.com/2008/07/vlcsnap-190652.jpg descent]] [[http://images.wikia.com/avatar/images/8/8f/Mental_Azula.png into]] [[http://4.bp.blogspot.com/_gIQapHdxQQI/THTpaIdZuHI/AAAAAAAAA6s/iojyvdxiKpk/s1600/Crazy+Azula.BMP madness]].
* Manga/DeathNote: [[VillainProtagonist Light Yagami]]. From [[http://media.animevice.com/uploads/1/10361/252258-1442635_light_animestocks_com__22.jpg mild]] [[http://media.animevice.com/uploads/1/10361/252261-1449928_light_animestocks_com__09.jpg temper]] to [[http://www.lightyagami.com/large/light-yagami-45.jpg his]] [[http://media.animevice.com/uploads/1/10361/252259-1449924_death_note___37___large_10.jpg grand]] [[http://media.animevice.com/uploads/1/10361/252256-1427496_light_animestocks_com__76.jpg finale]].
* Ratigan from TheGreatMouseDetective [[http://trueclassics.files.wordpress.com/2012/06/ratigan.jpg Going from this]] to [[http://4.bp.blogspot.com/-BDRc2GiU8Ks/Tz1Md9WL03I/AAAAAAAAAw4/Kasi_BoiLzY/s1600/Ratigancomplement.jpg to THIS]] after being OutGambitted
* [[Manga/JojosBizarreAdventure D'arby]] [[http://imageshack.us/a/img849/2097/darby1.jpg The Gambler]]. Reduced to a crazy and cackling guy after [[http://imageshack.us/a/img547/7721/darby2.jpg one]] [[http://imageshack.us/a/img202/5420/darby3.jpg bet]] [[http://imageshack.us/a/img138/2018/darby4.jpg too]] [[http://imageshack.us/a/img209/4044/darby5.jpg many.]]