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[[folder: Video Games ]]
* [[http://static.tvtropes.org/pmwiki/pub/images/tm2_substories_heartattack_9181.png The restaurant's owner]], who has collapsed due to a heart attack, under the eyes of Akane and the protagonist, in ''Franchise/TokimekiMemorial 2 Substories: Leaping School Festival''
* [[spoiler: Teddie Adelaide]] [[http://static.tvtropes.org/pmwiki/pub/images/mitsukni_teddie_heart_440.png suffering a heart failure]], during her storyline's mandatory event, in ''VideoGame/MitsumeteKnight''
* [[http://shimmie.katawa-shoujo.com/post/list/i%27m_gonna_die/1 The many many HNNNNNNGGG]] of [[VisualNovel/KatawaShoujo Hisao Nakai]]