!!Mixed Examples
* [[IlivaisX Iriana Estchell]] fits the typical characteristics, but she's not EXACTLY sick. However, she only has a handful of non-artificial organs and is very limited in the physical activities she's capable of doing, and will definitely go into a coma after five minutes outside. Why? Because she was made for the sole purpose of being the titular mech's pilot, without the intent of ever leaving it. Her body IS capable of regeneration mostly as a side-effect of her internal recycling so as to not require nutrients, but her source of energy is the mech. Without her battery, she's essentially immortal inside her Ilivais, but if she stays out too long, she'll eventually die.
* The {{Franchise/Buildingverse}} (''{{Webcomic/Roommates}}'', ''Webcomic/GirlsNextDoor'' etc.) has several more-or-less-seriously ill-people who play on this trope (but the illnes won't be fatal as the NobodyCanDie rule is in effect): Mag (She is permanently blind); Satine (Has VictorianNovelDisease); Jareth (when he caught the [[PowerIncontinence magical]] [[CatchYourDeathOfCold cold]] made an insufferably cute IllBoy too... [[UnexplainedRecovery He Got Better]]; later he also got mortally wounded by a WeaponOfXSlaying).

!!Female Examples
* Toki was dying from leukemia during the events of [[http://akaichounokoe.deviantart.com/art/Flashbacks-I-Alone-and-Frail-334638145 Flashbacks I]]. She gets better but the effects are still there.
* We have Anwen von Eyre from Wiki/{{Killerbunnies}} and she is ill with a progressive illness that will eventually take her life. She turned to villainy to find a cure if not something that will prolong her life.