!!Male Examples
* In the ''WesternAnimation/AvatarTheLastAirbender'' fanfic ''[[http://www.fanfiction.net/s/6245901/1/Three_Years_At_Sea Three Years At Sea,]]'' Zuko was "sickly" for most of his childhood, making him appear even weaker in comparison to Azula in his father's eyes.
* Lance Wabisuke-Hamilton from ''Fanfic/OnePieceParallelWorks'' has a mysterious illness that causes him to fall asleep at random times and makes him physically weak. However, {{Word of God}} states that Lance's condition is not life-threatening.
* Tim in ''[[http://www.fimfiction.net/story/29758/his-own-personal-heaven His Own Personal Heaven]]'' was diagnosed with colitis and fell out of touch with all his friends. He could only find consolation in fantasizing about himself with [[WesternAnimation/MyLittlePonyFriendshipIsMagic six colorful mares.]]

!!Female Examples:
* In the VideoGame/TouhouProject fanfiction ''[[http://www.fanfiction.net/s/9522160/1/Reimu-s-Illness Reimu's Illness]]'', because of her unstable (it is described as being up and down) health, Reimu falls ill with tuberculosis, human enterovirus 68, and viral meningitis and she is so sick that she's had to be transferred to a hospital in the city and be placed in something called an isolation box (which is akin to an incubator for premature infants).
** In [[http://www.fanfiction.net/s/9354387/1/Gensokyo-20XX-Rise-Of-Earth-full-Version Gensokyo 20XX]], she has been plagued with colds, depression, and various other ailments, even lack of sleep and appetite, requiring her to take so many medications to no avail. Ultimately, she was hospitalized and the doctors did all they really could.