* The 'Total Eclipse of the Heart' sequence was genuinely pretty touching.
** Also Yugi claims in that episode (36) that his friendship with Joey means more to him than card games. Given that card games are played to such obsessive levels in this show, that's saying a lot.
** "Must... risk life... for best friend..."
** The ending, when Joey and Yugi start WaxingLyrical, leading into the song No Matter What playing, and Kaiba, the last person you would expect, saying that he loves the song.
* Marik and Bakura's [[spoiler: death]] scene in which they sing "Stand by Me".
* "YGOTAS Sails Away" too.
** Especially when, in the midst of offering several different things in return for Bakura agreeing to sing with him, Marik finally says, "What if I told you I loved you?" Bakura is first shocked... but then, a little later, [[AwLookTheyReallyDoLoveEachOther he does sing after all]]. The fact that his voice [[DefrostingIceQueen softens]] ''ever-so-slightly'' when he reacts makes it.
* The part where Mako Tsunami gets back together with the ocean, especially because [[spoiler: the ocean finally speaks.]]
** Also Joey's surprisingly legit relationship advice he gives to Mako.
* Tristan's speech in episode 51.
** "It's okay Serenity. I've lived my life as nothing but a side character, fit only for spouting brainless quips and catchphrases. But now, I get to die the way I've always wanted: falling, screaming like a girl, into a pit of boiling hot lava, flesh being seared from my bones. If I do survive, I'll probably be unrecognizable. But if I do die, it'd be as a main character. It's funny; I used to think my voice gave me super strength. But now, I know the truth. And it's my love for you is what really gives me super-strength."
** And then there's the adorable Film/StarWars reference:
-->'''Serenity''': I love you.
-->'''Tristan''': I know.
* Joey's speech to Johnson in Episode 50 after being accused of copyright infringement (also doubles as a CrowningMomentOfAwesome):
--> '''Joey''': Yeah, I have a closing statement. Maybe we have committed copyright infringement. But you gotta know we've done everything in our power to support the Yu-Gi-Oh franchise! And if it weren't for us, I don't think the show would be nearly as strong as it is right now!
--> '''Johnson''': And where is your evidence of such?
--> '''Joey''': Look around, Johnson! There are more Yu-Gi-Oh fans now than ever before! And the more you try to stifle our creativity, the more we'll try to express our love for a show that's about more than children's card games! It's about fighting for what you believe in, and I believe in this show and its fans now more than ever! Because they believe in me!
** Followed by [[ThemeMusicPowerUp the classic Yu-Gi-Oh theme as Joey announces his attack]]. Incidentally, LittleKuriboh said on his [=LiveJournal=] that he made the abridged series to show that Yu-Gi-Oh was about more than card games and this is the purest expression of that.
* From episode 53:
--> '''Noah:''' Admit it. You don't really care for him.
--> '''Kaiba:''' Yes, I do!
* Still on the topic of Seto and Mokuba, in episode 14:
--> '''Seto:''' I have to beat Yugi if I ever want to see my little brother again. I miss you Mokuba.
* In a deleted scene of ''Melvin'd'', Melvin calls Florence out on his hypocrisy in trying to prevent Melvin from destroying the world when Florence has the same goal. Instead of invoking [[TheOnlyOneAllowedTODefeatYou The Only One Allowed to Destroy the World]], Florence instinctively answers, managing to back himself in a corner, leading to this speech:
--> [[DoesThisRemindYouOfAnything "I'm not fighting for this world. This world can go to Hell for all I care. I'm fighting for-"]] [[{{Beat}} *beat*]] [[DoesThisRemindYouOfAnything "The truth?... Marik, there's something you need to know... It's about us. Marik, I- I hate you. I hate you with all my heart. I hate you more than I've ever hated anybody. I hate you so much that I can barely take it. In fact, I want to go on hating you for the rest of my life. If our world is destroyed, well, I won't be able to hate you anymore."]]
** A few years later, this takes on... [[HomeStuck a whole different meaning.]]
* In the 3D movie, Yami Yugi admits that [[ItHasBeenAnHonor it's been an honor]] playing card games with the other protagonists. [[ThrowTheDogABone Even Jaden]].
* Joey getting annoyed at Yami for making jokes about Mai when she's in a coma. Am I right?
* Episode 55 continuing to show us that for the all the crap and mean things he says to Mokuba, Seto really does care about his brother... even if he finds it hard to admit it in front of everyone.
* Episode 56 ends with the gang mourning the end of 4Kids. Despite the dub for ''OnePiece'' they were thankful for 4kids introducing Yu-Gi-Oh and other anime to kids.
** "[[VerbalTic Nyeh]], [[BigDamnHeroes Brooklyn rescue]]."
* In one of the Evil Council episodes, they manage to kill Yugi, Psychoshipping becomes canon, Bakura is voted villain of the year and everyone agrees that Florence is the manliest name ever. Bakura says it's the happiest day of his life, and he actually ''sniffles''. Sniffles. Bakura.
* Most of Marik's cover of [[Disney/HunchbackOfNotreDame "Out There"]] was a funny moment, but it was still kind of touching to see the final line synched up with Marik [[FirstTimeInTheSun emerging from the tomb for the first time]].
* Marik's talk with Odion during the duel between Yami and Melvin. While it wasn't ''quite'' the heartfelt apology that his [[YuGiOh canon counterpart]] gave during the same scene, Marik still managed to swallow his ItsAllAboutMe attitude long enough to at least let Odion know what a great brother he was. The fact that Marik [[spoiler:intended for these to be his LastWords]] makes it double as a TearJerker.