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* On the week of November 8th, 2010, ''XKCD'' creator Randall Munroe put out a comic saying that he would not be drawing new comics for a little while because of family illness. In the Alt-Text, however, he asked for people to send him distracting online games. The result? 2700 by noon of the same day.
** He revealed exactly ''what'' the family illness is in July 2011: [[http://blog.xkcd.com/2011/06/30/family-illness/ his fiancee has Stage III breast cancer]]. In that blog post, he thanked all the people who sent him flash games.
** [[http://xkcd.com/1141/ This]]. Two years. "And they were big years..."
** Still not too mopey though:
--> "Zarg isn't a word."
--> "But ''caaaancer''."
--> "...OK, fine."
* [[http://xkcd.com/55/ "My normal approach]] is [[WhatIsThisThingYouCallLove useless here]]."
* [[http://xkcd.com/767/ This strip]] may not seem too special, but then you read the Alt-Text...
* [[http://thephoenix.com/Boston/News/48208-wisdom-of-crowds/ Maybe wanting something does make it real.]]
* [[http://xkcd.com/614/ He'll even get you a extension cord.]]
* [[http://xkcd.com/346/ "Diet Coke+Mentos"]] is quite nice.
* [[http://xkcd.com/896/ Just remember that if you want to do this stuff, you're not alone.]]
* [[http://xkcd.com/442/ "XKCD Loves The Discovery Channel]], as well as being a [[SugarWiki/MomentOfAwesome really cool]].
* [[http://www.xkcd.com/515/ This]] one; rather heartwarming in a psychopathic sort of way.
* [[http://xkcd.com/104/ This]] is pretty heartwarming as well. That's real devotion right there.
* This [[http://xkcd.com/506/ one]] too, which showcases just how much two people can be meant for each other.
* [[http://xkcd.com/569/ This]] may be the most uplifting and inspiring thing on the Internet.
* [[http://xkcd.com/572/ One more case]]
* [[http://xkcd.com/162/ Everyone wishes that some moments could last forever. This girl is doing something about it.]]
* [[http://xkcd.com/502/ *sniff* Dammit, mom...]]
* [[http://xkcd.com/289/ This strip]] is incredibly sweet.
* [[http://www.xkcd.com/260/ This one too.]] "Give."
* [[http://xkcd.com/150/ "Because we're grown-ups now, and it's our turn to decide what that means."]]
* [[http://xkcd.com/791/ This one]] is good.
* [[http://xkcd.com/201/ Merry Christmas from xkcd.]]
* [[http://xkcd.com/112/ This Venn diagram]] (setting aside the joke of Vanilla Ice falling into "People who constantly show me new things to love about the world" and "People I want to spend the rest of my life with").
* The week they decide to do parodies of other famous webcomics. They then get around to ''{{Megatokyo}}''. By frame two, [[http://xkcd.com/142/ they call the whole thing off, believing people (especially creator Fred Gallagher) would find it mean spirited and in bad taste]]. They decide to bake him a cake instead.
** It seems more like they're mocking him for being easily offended. The ''[[http://xkcd.com/160/ Penny Arcade]]'' parody a little later on, however... (when not regarded as an extended gay joke, anyway).
* [[http://xkcd.com/40/ "Like a beacon"]]
* [[http://xkcd.com/99/ "i love you"]]
* [[http://xkcd.com/433/ This.]] "There's still time to leave and find a non-crazy girl." "Not even ''slightly'' interested."
* [[http://xkcd.com/828/ 828]]'s message is quite uplifting.
* [[http://xkcd.com/417/ This one]] in a really [[MindScrew strange way]].
* [[http://xkcd.com/941/ I've looked at clouds from both sides now.]]
* [[http://xkcd.com/943/ Apparently, yes!]]
* [[http://xkcd.com/659/ Legos can become anything.]]
* [[http://xkcd.com/48/ We are just two people...]]
* The alt-text of the [[http://xkcd.com/374/ Journal strip]], from a certain point of view. In a weird way, it could even be a bizarre FriendshipMoment.
-->'''Black Hat Guy:''' And the journal is filled with all the things I'd say to her if I were nice like you. I burn it when it's full.
* [[http://xkcd.com/731/ The most exciting new frontier is charting what's already here.]]
* [[http://xkcd.com/667/ Especially if you read the ALT text.]]
* [[http://xkcd.com/968/ I want to give you everything, just to see what you would do with it.]]
* Randall finally [[http://blog.xkcd.com/2011/09/12/672/ married!]]
* [[http://xkcd.com/1000/ 1000 comics...]] wow... and remember, Randall, [[AltText you are never alone]].
* [[http://xkcd.com/847/ This]] until the MoodWhiplash at the very end.
* [[http://xkcd.com/1053/ You're one of today's lucky 10,000.]]
* The six-part [[http://xkcd.com/1/ floating]] [[http://xkcd.com/11/ barrel]] [[http://xkcd.com/20/ and]] [[http://xkcd.com/22/ flying]] [[http://xkcd.com/25/ ferret]] [[http://xkcd.com/31/ series]].
* [[http://xkcd.com/572/ Here]], the last panel joke aside, is pretty good, because it shows he did find happiness.
* [[http://xkcd.com/1110/ I just didn't expect it to be so big.]] The ending [[spoiler:("I wonder where I'll float next"), once you realize what the first ever strip was]], can be a tearjerker.
* Here's one from the What If section: [[ItMakesSenseInContext But if you are stuck in Svalbard and want to make the sunset—or sunrise—last a little longer, you can always try spinning counterclockwise. It’s true that it will only add an immeasurably small fraction of a nanosecond.]] [[http://what-if.xkcd.com/42/ But depending on who you’re with... it might be worth it.]]
* [[http://xkcd.com/1190/ Time]]: The two main characters learned of an impending [[ApocalypseHow Class Zero Apocalypse]] that will result in TheEndOfTheWorldAsWeKnowIt for their home. By sheer accident the area they reached is actually safe, but there is no time to go back for the rest of their people, for the risk would be too great. They did not intend to leave their home forever, but it happened and now they must say their goodbyes to it. Upon hearing that, they share ''one'' glance and then proceed to '''RUN''' back home. And they make it back just in time to [[EverybodyLives Save Everyone]] too!
* [[http://xkcd.com/1259/ I'll remember your bee, orchid.]]
* [[http://xkcd.com/1282/ "Monty Hall"]], in an odd kind of way.
* [[http://xkcd.com/1322/ "Winter"]]
* Why didn't anyone put [[http://xkcd.com/372/ this]] yet?!
* Billion Story Building in What-if. Most of the time, the questions are silly (but interesting) and from adults. This one is from a 4.5 year old girl and equally silly (but interesting). The heartwarming part is that he not only directly addresses the What-if to her, he words things to make more sense to a person with not as much life experience while still treating her and her question with respect. And to boot, while he says the basis of a her question is impossible, he suggests a more practical possibility and encourages her to explore the sciences because she may be the one to solve those problems.