* The Season 3 episode "The Wedding," when Crystal marries Dan's father, Ed. Dan has been vehemently opposed to their relationship the whole time. At the last possible minute, as Roseanne walks down the aisle alone (as Matron of Honour), Dan--who's not speaking to anyone, including Roseanne--runs up and joins her. The look on Ed's face is gold.
* The entire episode of Darlene's wedding but especially Mark and David's conversation about their parents as Mark ties his tie:
-->'''Mark:''' Will you just shut up about them already? Man, they never did anything for us. They kicked me out of the house when I was sixteen, and they treated you like a dog. The Conners are your parents now, ok? You and me both. They saved our asses.
-->'''David:''' Well, Mom and Dad gave us life, ok? Maybe one of us a little more than the other, but still.
-->'''Mark:''' Hey, hey, hey. It's a slap in the face to the Conners for you to be hung up on a couple of jerks who haven't even bothered to call in the last four years.
** Made better a moment later. As Mark gives David the above advice, he's tying his tie for him.
-->'''David:''' Hey, where'd you learn to tie a tie?
-->'''Mark:''' Dad taught me, now I've taught you. You don't need him for anything now.
* The episode where David moves in with the Conners. They spend the entire episode telling David that he can't live with them. They go over to apologize to David's mother, since they thought she came up with the idea, which she didn't (Darlene and David cooked up the whole scheme in an attempt to stay together when David was supposed to move). When they mention it, she flies into a rage, including calling David a worthless little bastard ''to his face.'' The empty look on his face is heartbreaking. Roseanne had already shredded her previously in one of her glorious beatdowns, but hearing that was enough for her to simply say:
-->'''Roseanne:''' All right, I'm changing my mind. David, you can come live with us if you want to.
* Darlene is playing the role of the cynic UpToEleven in the Disney World episodes...until she meets Franchise/WinnieThePooh and melts into a puddle of fangirl gushing about how he was the first book she ever read and he's always been her favorite.
* At the end of the series, [[https://www.youtube.com/watch?v=fDRIzYxYyLc everyone visiting]] Darlene and David's baby, Harris. David sums everything up in the most wonderful way.
-->'''David''': Hey. Had a lot of visitors today, didn't you? I hope nobody frightened you, because they all love you very much. There's a lot of love here, in this house. You might hear some yelling or some-some naughty words, but... sometimes the love is so strong that they can't contain it.
** During the visits, we also find out that Becky and Mark are expecting. Mark asks when to let everyone know, and Becky says to put the news off for a little while, so that Darlene and David can have their moment in the sun. Later, after everyone else has left, Mark comes back to play with Harris by himself.
--->'''Mark''': Oh, man... this dad thing is going to be great.
* In the first episode of the series, Roseanne and Dan are fighting over whether or not Roseanne has all of the responsibility around the house (and Dan is trying to prove he has plenty of capability for domestic tasks by making dinner). Suddenly, Darlene gets a bad cut on her finger, and the two drop the fight and whisk her away into the kitchen. Dan holds Darlene's finger over her head and bandages the wound, while Roseanne comforts the very freaked-out Darlene by reminding her of the fun time they all had at the demolition derby. When the wound is treated and Darlene runs merrily on her way, Roseanne and Dan exchange a look, and Roseanne asks Dan if he's hungry and starts preparing dinner. They each came to the realization that, while they each have different strengths, they work extremely well as a team.
* Two Christmas episodes involving Darlene:
** In "Santa Claus", from season 4, Roseanne finds out Darlene's "friend" Karen is actually an older woman who runs a bookshop. Not only that, but Darlene acts with Karen like the "good" daughter Roseanne wants to have (Darlene helps around the store, has nice manners, and helps with Karen's young son Sammy), and even has even showed Karen stuff that she's written, which she never does with Roseanne; naturally, Darlene and Roseanne have a fight about this. Near the end of the episode, when Darlene comes home, without saying a word, she pins a story she's written on the refrigerator.
-->'''Roseanne:''' I guess I do get a Christmas bonus after all.
** The following season's Christmas episode, "It's No Place Like Home For the Holidays", all of the Conners are separated from each other due to a blizzard; Dan and DJ are at home with Nancy and Marla, Becky (not seen) is at a hotel with Mark, Roseanne, Jackie, Bev and Nana Mary are at the diner, and Darlene's at David's house. Darlene and David get in a fight because he wants to and she's not ready, and the only reason she doesn't go home is because of the blizzard. Then David's mother gets home, and after seeing how his mother treats him, Darlene makes up with him. Not only that, but when she gets home the next morning, Darlene shocks everybody by kissing Roseanne on the cheek.
-->'''Roseanne:''' [[BrickJoke See, Mom, I told you there's a God.]]
* In [[https://www.youtube.com/watch?v=0Il8jV6r-tk "War and Peace,"]] Darlene is the person who has to post Dan's bail after he's arrested for giving Fisher a (well-deserved) beatdown for hitting Jackie. While this is mostly a Crowning Moment of Funny on Darlene's part (she spends the scene dropping sarcastic comments and jokes), she does eventually get serious and tell Dan that his giving Fisher what he had coming to him was a cool thing for him to do.
* In "Lovers' Lane," a Season One episode, Roseanne and Dan find out that Becky has a crush on Chip, a boy at the bowling alley. They have a lot of fun teasing her by claiming that they're going to be as embarrassing as possible when they meet him. When Roseanne does go to the snack bar where Chip works, though, she ends up being nice, letting him keep her change, and pretending that she doesn't know Becky (though she does wink at her just to give her a scare). Chip comments that Roseanne is "pretty cool"; Becky realizes he's right, smiles, and agrees.
* "It's A Boy" has a moment that is also tearjerking at the same time. It's when Roseanne tells Dan she has agreed to let Darlene's boyfriend David live with them rather than move away with his mother. Dan is upset that she did this after they initially agreed to say no, but when Roseanne tells him that David's house is the kind ''she'' grew up in, he quietly says "That bad?" and leans back, sighing as he accepts that he can't let David live that way. It's a beautiful moment of these two caring about another person that much, but makes you sad (having seen what David's mother is like) that Dan understands immediately how bad things are, without Roseanne having to give any further explanation.
* DJ actually gets one in "Maybe Baby." There is a chance that something is medically wrong with Roseanne's unborn baby, and after DJ finds out, he tells her he'll support her no matter what her decision is, which is what she had been desperate to hear from someone for the entire episode.