!Per wiki policy, Administrivia/SpoilersOff applies here and all spoilers are unmarked. Administrivia/YouHaveBeenWarned.

* The way Dante acts after regaining his memories and brother in the mansion. Suddenly, this hedonistic punk sounds ''very'' young. You begin to realize just how much going through such a shitty life without remembering how you even got there was weighing him down.
* How Dante [[CharacterDevelopment develops throughout the story]], going from a dick, to a really likable guy. Vergil puts it best during Mission 16:
-->'''Vergil''': You really do care about her, about all this. You once said you didn't give a shit.
** His very caring nature comes into play when Kat is involved:
--->'''Dante''': Listen, I never asked for your help, but you gave it, and I appreciate it. I trust you, you can trust me too.
** Another moment showing how Dante matures throughout the game:
--->'''Kat''': You're gonna stick with us to the end, right?
--->'''Dante''': Count on it.
* Basically, almost ''every'' individual moment in Mission 20 is heartwarming.
** Dante's argument against Vergil about ruling humanity:
--->'''Vergil''': Humans are frail, they're like children, they need our protection. Not just from others, but from themselves! We - you and I - have saved them.\\
'''Dante''': ''You and I'' have saved them?\\
'''Vergil''': Who else?\\
'''Dante''': A human.\\
'''Vergil''': Kat was useful but -\\
'''Kat''': ''Useful?''\\
'''Dante''': Kat saved my life, Kat held out under ''torture'' to keep your existence a secret! Kat led us through the tower to Mundus' lair. We would've failed twenty times over if it wasn't for her!
** Kat begging Dante to spare Vergil's life, in spite of his ambitions and cold treatment towards her. Dante even looks somewhat relieved afterward.
--->'''Kat:''' I know who you are. You are Dante. Nothing more, and nothing less.
** Dante carefully and patiently lending Kat an arm to help her walk to where they can better see the aftermath of the battle. His obvious protectiveness and affection is nearly a complete reversal from how dismissive and harsh he originally was with her, and how comfortable she is with accepting his help really speaks to her trust in him.
** Also, Kat putting her hand on Dante's cheek.
* When Kat is being beaten by the SWAT team, Dante puts his hand over hers to comfort her.
-->'''Dante:''' I ''will'' come back for you.
* Also, in the mission where Dante and Kat are in the Virility Facility:
-->'''Kat:''' It's a vial, containing a spell I made from a variety of--\\
'''Dante:''' *touches Kat's shoulder* I don't need to know.\\
'''Kat:''' You jump, I twist.\\
'''Dante:''' Are you serious?\\
'''Kat:''' Trust me.\\
'''Dante:''' I jump, you twist.
* When the trade with Lilith and Kat goes to hell, Dante picks Kat up bridal style and shields her with his body, getting shot while running back to their car.
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