* An extremely fast one in ''ScaryGoRound'', which introduced a parody of MichaelJackson with a CreepyChild servant just a couple weeks before his death. The author commented:
-->'''John Allison:''' The last thing anyone expects, when they have introduced a character who is a kind of grotesque version of a world superstar, is for that superstar to die. It is entirely possible that Michael Jackson sat down to read ''Scary Go Round'' yesterday, began to turn slowly purple at what he saw, and collapsed clutching his arm. Actually I know that isn't true. Jackson was on record (citation needed) as more of a ''DresdenCodak'' man.
* In Webcomic/CuantaVida : "If I killed 'em, they'ed replace 'em with someone faster." [[spoiler: Poor, poor Liam]]
* ''Webcomic/{{xkcd}}'': The mouseover text for [[http://xkcd.com/625/ strip #625, "Collections"]], reads: "You know what really helps an existential crisis? Wondering how much shelf space to leave for a Creator/TerryPratchett collection."
* [[http://questionablecontent.net/view.php?comic=858 The last panel of this]] ''QuestionableContent'' strip (in which Dora freaks out about possibly sabotaging her relationship with Marten) has this effect if you've read through the rest of the series.
** It gets worse -- Jeph Jacques has admitted to a dependence on alcohol and a series of mental issues, so the dozens of strips about depressive people heavily-drinking to unwind gets a bit uncomfortable.
* Oh, Creator/AndrewHussie. Must you splatter blood on ''every'' happy memory in ''Webcomic/{{Homestuck}}''? While a full list of touching or funny moments to later endure the [[CerebusSyndrome grim hand of Cerebus]] would break the wiki, one of the best has to be the Wayward Vagabond's Can Town, which started out as a funny thing he did for no real reason and became soul-destroyingly tragic when we learned about [[http://www.mspaintadventures.com/?s=6&p=003701 this]].
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