* Seiya desperately trying to clean his room before letting Saori pass in Episode 4
** Even better because, when Seiya opened his door, he was shirtless and in pajama pants (he was washing his hair in the sink when that happened). Cue to him freaking out when it turns out the one checking in was [[AccidentalPervert Saori]], who might br [[TheOjou the richest girl in the world]] but is ''still'' [[NotSoAboveItAll a girl around his age deep down]]. And who [[LuminescentBlush blushes]] from head to toe and [[ShrinkingViolet shyly]] waits at the door until Seiya is ready.
* Episodes 29 and 30 of the anime features [[TheChewToy Corvus Jamian]]. Every single scene with him is a CrowningMomentOfFunny.
** Also, Jamian's death: the [[AllInTheManual manga inserts describing the cloths]] show his cloth has wings (and Seiya ''did'' fly with his wings, once he discovered how to make them appear), but he died [[EpicFail falling off a cliff]].
* Seiya trying to escape from the hospital with Miho chasing after him is quite funny. [[spoiler: Miho CATCHING HIM and having his arms tied up so he can't escape again]] is hilarious.
** Few later, Seiya and Miho have a rather... romantic talk before he leaves to Greece to reach the Sanctuary. It's [[HeartwarmingMoments a rather sweet scene]] with them recalling [[ChildhoodFriend their shared past]] and him promising to come back to her and the orphans... [[spoiler: and then [[MomentKiller the three kids that Seiya personally befriended fall off a nearby tree]].]] Meeep.
* Docrates, a gigantic guy looking for Seiya and cia with the Dark Saints, running away when hearing police sirens. "Oh, no! The police!"
* When Seiya and Shun arrive at the First Prison of Hades’ Underworld, they are advised by a Specter mook to remain in complete silence, in order to respect Lune, the current Judge of the Dead, who hates noises. Seiya then proceeds to make lots of loud noises, like sneezing and generally provoking the mook. This is made even more hilarious in the original Manga, where he actually ''farts'' just to provoke the Specter.