* The narrator telling about the events, especially in the first episode of the 1st season. This is courtesy of the English hearing captions in the DVD. Even though it's trying to help, just listening to it and watching most of the scenes sounds funny.
* Des and Jake's interaction is usually made of funny:
--> '''Jake''': ''Why'' is it that whenever I talk to you, I want to punch you in the face?!
--> '''Des''': ...'cause you're mean?
* [[DeadpanSnarker Rose]] has her moments as well.
--> '''Martin Poole''': Ok, it's official, I'm aroused.
--> '''Rose''': Really? I don't see anything.
* All of this has nothing on Jake and Malachy's snarkfests, however. Good ''grief''.
** Take, for example, the instance when Jake nearly gets himself killed (again). Malachy starts railing at him, and Doyle retorts "I'd ask you to come down and help me, but of course you'll never get your walker down here!"
** There's another instance when Malachy is just [[ItMakesSenseInContext getting out of jail]], and Doyle asks him how it went. Malachy's response? "Dandy, they're talking about naming a wing after you."
* Jake vs. pompous airbag Garrison Steele. [[http://www.youtube.com/watch?v=yD-Oqi_TjM0 Hoo boy]].
* Des, looped up on painkillers and trying to stealthily peer down a med student's blouse (after calling her an angel and generally babbling).
* Bruce thinking Jake, Des and Malachy were hitmen because they were standing in the road in front of his house "trying to steal those [[BuffySpeak snow... sled... machine... things]]."
* Martin [[spoiler: drugging and kidnapping Rose]]. [[RunningGag Again]]. [[spoiler:Malachy gets him back in the end by drugging him right back and leaving him passed out on an armchair.]]
** Also, his being shot in the behind for gambling too much... and then shot again. Probably because he deserved it.
* Des figures out that Tinny's back in town, then slams the computer shut as Malachy walks in. When Malachy asks him what's wrong... "[[spoiler:I got hit by a car]] and I'm on drugs. *Nonchalant shrug*"
* Jake tells Leslie that the case he's in has just gotten bigger after being humiliated by his ex-[=RNC=] colleagues when he was caught naked and cuffed.
--> '''Leslie''' : "Not from where I'm standing."
* Jake is [[SarcasmMode *excellent*]] with [[http://www.youtube.com/watch?v=9yL74k2hG_Y&feature=related children.]]
* "What are you two whispering about?" "Nothing. ...Des has fleas." "I don't have them ''anymore''!"
* Jake accidentally holds up a bank in "High School Confidential", resulting in a media frenzy and the entire police force arriving at the station.
* How Des scares off an attacker: runs at him screaming and waving his arms like a windmill.
-->'''Jake''': What the hell was ''that''?!
-->'''Des''': ...the element of surprise!
* Jake and Maurice butting heads when they were telling the [=RNC=] about what happened to Leslie and Hood. Maurice makes Jake look like a wuss, idiot and a chicken. Jake makes Maurice looks worn, tired and not neat with his clothes. In addition, Jake looks tough and confident in his stories while Maurice looks cool and sophisticated in his stories.
* Des' reaction when he sees Jake [[spoiler: after the latter missing for two months]] in the season 5 premier. Doubles as a moment of [[Heartwarming/RepublicOfDoyle Heartwarming.]]
-->'''Des''': What's up.
-->'''Jake''': "What's up"?!
-->''*Des runs at Jake and hugs him*''
* Des telling Tinny that he's a grown man with his own apartment now, and they shouldn't need anybody's permission to date each other. Cue his phone ringing.
-->'''Des''': Oh god it's Jake he's on to us!