* Luigi upon being offered decaffeinated coffee: "I will shoot you in the [[NoIndoorVoice FACE]]!"
* Luigi again: "I will find a hole and fuck it!" combined with him doing pelvic thrusts into his hands (with his thumbs and forefingers in the shape of a vagina) and a "sproing!" sound effect in the background.
* [[RuleOfThree And again.]] "What's this, rat piss?!" STAB STAB STAB. In fact, Luigi, Pavi, Amber and Mag all act like children during the scene. Mag seems less concerned with the fact that [[AxCrazy Luigi is stabbing the attendant to death]] and more with the embarrassment of the thing, and Amber acts like some smug, slightly-older brat who, for once, has the high ground. And then [[OnlySaneMan Rotti]] turns up.
** "But he/she-!" As they immediately point at each other...
* [[ILoveTheDead Grave-Robber's reaction to ending up in a pile of corpses]]; [[NightmareFetishist "Jackpot!"]]
* The Repo Man has [[DopeSlap a unique way of silencing his victims.]]
* The reactions of both Luigi and Pavi in [[http://www.youtube.com/watch?v=Jx8s19m7iGw this clip.]]
** And when [[spoiler:Rotti tries to convince Shilo to kill Nathan]], they start strangling each other.
* All of "Thankless Job", if you've got a [[BlackComedy certain]] [[BloodyHilarious sense]] [[CrossesTheLineTwice of humor]].
* "You're real?" [[CaptainObvious "...Duh."]]
* Grave-Robber's number, "The 21st Century Cure," particularly the moment when he screams out '''"GRAAAAAAAAAAAAAAAAAAAAAVES!"''' and is [[WithCatlikeTread immediately discovered]]. A very clever fourth wall joke.
* When Nathan calls Shilo after she meets Blind Mag while he's out on a repossession, and the victim cries out.
--> '''Shilo''': Your patients need you. *victim cries out in pain* Dad, who's that?
--> '''Nathan''': Oh, that? One of my patients, he's sick. *NeckSnap*
--> '''Shilo''': Will he live?
--> '''Nathan''': It's looking grim.
* Luigi's reaction to Rotti leaving everything to Shilo, going from calling for Nathan's death as he enjoys his popcorn to screeching his displeasure as the popcorn goes flying.
** That whole bit is hilarious:
--> '''Luigi''': ''(with a huge grin)'' KIIIIILLLL HIIIIM!
--> '''Shilo''': No...
--> '''Rotti''': And I'll leave you GeneCo!
--> '''Luigi''': ''(still grinning)'' WHAAAAAT?!
--> '''Pavi''': All of it?!
--> '''Rotti''': Oh, yes!
--> '''Pavi''': Oh, ''no!''
* The opening song to the Genetic Opera features a Band Leader who is an undeniable {{Keet}}. As the song ends, you can hear the poor guy coughing and gasping for breath over the amount of boundless energy he's got!
-->'''Band Leader''': Hey hey, hey hey! Hey he-HAUGH ACK!
* [[http://www.youtube.com/watch?v=NqBiJBdmREM "Bravi"]]. It's best summarized with the following youtube comment: "A murderer, a rapist, the king of the city and the queen of addiction [[VillainsOutShopping doing]] [[MundaneMadeAwesome TV commercials]]."
* [[https://www.youtube.com/watch?v=1HO3MrK1arY This]] deleted scene. Apparently, Graverobber thinks throwing a bale of hay at Amber will distract her enough to let him and Shilo escape. Her expression is ''priceless'', especially since it lands a good two feet from her: she's looking at him like, "Really? ''Really?''"
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