!!!Main series:
* Doakes' face when he [[http://www.nuzlocke.com/pokemonhardmode.php?p=22 kept spamming Magnitude.]]
* Ruby, a man of priorities, gives us this exchange as Gulliver the Pelipper is flying him over Mossdeep while they're chasing Team Magma:
-->'''Ruby:''' Hey is that a town?
-->'''Gulliver:''' But what about Team Mag-
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=9 "Who's there? Show yourself!"]]
* "Man, they don't pay me enough to edit these pages."
** '''''Goddamnit Ralph!'''''
* Sawyer's self esteem HARSHLY FELL.
* "I don't understand... how could ''water'' be ''good''?"
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=30 The Warden getting his teeth back.]]
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=18 Pretty much this entire comic.]]
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=42 This exchange]]:
-->'''Announcer:''' Let's see what you folks down in the stands think about our upstar little challenger...\\
'''Mr. Fuji:''' I think he's cool. Much Poke-respect.\\
'''Erika:''' He's pretty chill. Y'know, for a square.\\
'''Bill:''' I think...\\
'''Lt. Surge:''' '''-I THINK HE SUCKS AND HE OWES ME A [[PrecisionFStrike FUCKING]] GYM!'''
* A good MoodWhiplash moment. During Ruby's final battle with Gary, after Bruce fails to finish off Blastoise with a Blast Burn and must recharge, Blastoise grabs Bruce, fires off a Hydro Pump point-blank, [[EpicFail and misses]].
* Some moments with Ruby's conversation with Giovanni in the finale such as showing him the Kabuto, and this exchange:
--> '''Giovanni:''' Fortunately you still have the Masterball so you can end all of thi-\\
''[Ruby breaks the Masterball]''\\
'''Giovanni:''' ''[{{Beat}}]'' WHAT THE [[PrecisionFStrike FUCK]]\\
'''Ruby:''' Sorry, Giovanni... but rules are rules. ''[Flies away on Bruce]'\\
'''Giovanni:''' [[CallBack WHAT RULES]]?!
* Giovanni and Maxie in prison. Fucking priceless.
-->'''Maxie:''' So... How do you feel about water?
* When Ruby finds [[spoiler: Hilbert's]] body in the closet his response of "Arceus Christ" is just hilarious.
* Ruby's reaction to being [[spoiler:forced to pick Oshawott]]. The expressions on [[spoiler:Oshawott]]'s face make it even better.
* Ghetsis has only just shown up and his speech is golden. "Allow me to reveal a simple truth. Pokemon fucking hate you. Seriously, you capture and pit them against each other their will. Would they fight back if they wanted to be caught?"
** And the cop telling them about orders to "liberate" the park. After a complaint about freedom of speech, "Oh yeah? Well I've got freedom of repel." ''[cue using the pepper spray to get them out]''
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=58 Meeting N:]]
-->'''N:''' Your Pokémon... it's talking.\\
'''Ruby:''' No he's not.\\
'''Luke:''' [[BlatantLies No I'm not.]]
* Ruby sees [[HotScientist Professor Juniper]] for the first time:
-->''[[StatOVision MILF ALERT!! ENGAGE IN 3... 2... 1...]]''
-->'''Ruby:''' Wait a minute...
-->''[Ruby sees Bianca peeking out from behind Juniper]''
-->''[[StatOVision ABORT!! ABORT]]!!''
-->'''Ruby:''' ''[while running away]'' FUCK FUCK FUCK
* [[http://www.nuzlocke.com/pokemonhardmode.php?p=82 The first course]].
** Ruby's Pansear VS. Cilan's Pansage.
* Ruby stealing, Cheren and Bianca's gift, and his plans for [[ButtMonkey Senor Fluf]] once he finds what's inside.
--> '''Bianca:''' [[http://www.nuzlocke.com/pokemonhardmode.php?p=60 FUCKING MONKEY]]!!
** "Yeah, back in college me and Juniper did [[DoubleEntendre "experiments" together]] all the time..."
* Fennel's brief flashback of her time at Castelia University with Juniper after Bianca asks how she knows the detailed effects of Dream Mist. The strip makes the use of Dream Mist out like a bad LSD trip.
-->'''Fennel:''' ...I read it in a book. ''[Ruby knows she is lying]''
** What made it more amusing was Minccino's expression in the flashback with Fennel and Juniper can be seen as funny given the two were on a MushroomSamba.
-->'''Nuzlocke:''' Don't do drugs. You'll make Minccino sad.
** To add to that, the Plasma Grunts seeing Satan just chilling behind Ghetsis is pretty funny.
* Ruby and Cheren decide to team up. Cheren takes things to far and ends up ''ripping a heart out of a grunt's chest.'' Grunt's response?
--> '''Grunt:''' What the hell, man...
* This moment in the museum:
--> '''Burgh:''' Castelia...? ...That's MY turf!
--> '''Ruby:''' And who are you suppose to be?
--> '''Burgh:''' I'm a friggin' gym leader, who the hell are you?
--> '''Ruby:''' Wow. A gym leader not being in their gym and actually doing their goddamn job. There's a surprise.
* Ruby and a Petilil have a [[{{UsefulNotes/Kawaisa}} kawaii showdown]].
** And the Plasma Grunt's subsequent reaction of pure horror.
** It's even funnier now that there is new merchadise on the site shop showing them in "Kawaii-Mode".
* Ruby's reaction to Bianca asking Iris to be her bodyguard despite being younger than she is, and seemingly implying that she chose her because she was [[ScaryBlackMan Black]]. His reaction is then echoed by Ghetsis in the following scene.
--> '''Ruby''': I can't tell if you're being racist or just retarded right now.
* Ghetsis and Bronius discussing people from Johto and their [[ScrappyMechanic calling habits]].
** "There is nothing wrong with people from Hoenn" in the same panel with Ruby about to break into a window on a vehicle.
* The entire arc where Ruby catches [[spoiler: Victini]]. First, when Ruby finds him, the [[spoiler: Victini]], in the dark, makes a BadassBoast about itself, only to be interrupted by them turning on the lights, revealing he lives in a modest apartment. Which soon Ruby mocks him for only being lvl. 15, while Pauly accidentally views [[spoiler: Victini's]] blog, hitting his BerserkButton. Which leads to Ruby pelting him with a mountain of Pokeballs before he gives up. Ruby also gets some nice revenge on Burgh shortly afterwards.
* Pretty much every thing about Episode 9.1. Here are some notable examples:
** The famous scene with Bianca and her father in Nimbasa City was TearJerker in the games; in this comic, it becomes a SoapOpera parody.
** Vincent's less than amused face when Ruby enters him into an elegant-themed musical. Bonus points when Ruby off-handedly mentions that he intended to enter Princess, but selected him instead. As for the play?
--> '''"It. Was. Elegant!" -Nimbasa City Times''
* Episode 10 has Ruby and Luke "recruited"[[spoiler: or get sent to jail]] to take down some Plasma Grunts. All that is needed to know is Luke smoking something, Ruby killing the grunts thanks to Clay, and needing therapy as said gym leader leaves.
* ''All'' of Ruby's taunts towards the Shadow Triad in [[http://www.nuzlocke.com/pokemonhardmode.php?p=68 episode 11]].

!!!Robotv7's Nuzlocke Challenge ([=FireRed=] and Sapphire):
* From Robot7's comic there's his attempt to make his Hitmonlee more unique.
--> Let's see what [=TMs=] we have... *finds Attract* oh god yes...
* Also from Robot:
-->'''Robot:''' Man, i should switch Pchooooo out... (Beat) Naw, you can do it Pchooooo!\\
'''Pchooooo:''' ''[sweat]''\\
'''Robot:''' We need a critical hit.\\
''Not a critical hit.''\\
'''Robot:''' ''[gasp]''\\
'''Pchooooo:''' ''[tears]''\\
''[[PsychoticSmirk Machop used..]] [[spoiler:[[EpicFail Focus Energy!]]]]''
* Robot altering Dewford's trendy phrase.
-->'''Kid:''' Are you sure...?\\
'''Robot:''' Positive.\\
'''Kid:''' OK! Hey everyone! The new trendy thing to say is [[spoiler:'''''ADULT TOYS!''''']] ''(Robot runs off laughing)''

!!!Freddy's Nuzlocke Adventure:
* Rosie's [[http://imgnook.com/hZrER reaction]] to her first real battle being against an Onix. That face is ''priceless''.
-->'''Rosie:''' [[WhatTheHellHero what the fuck man]]
* Freddy encounters his rival in Pokemon Tower, with some Nuzlocke-flavored Fridge Logic adding a touch of hilarity.
-->'''Gary:''' Your Pokemon aren't dead. Why're you here? Eh, no matter. I can at least make 'em FAINT.\\
'''Freddy:''' (pause as it hits him) '''''YOU SON OF A BITCH'''''
* Lance's first apperance:
-->'''Lance:''' Are you a helpless 10 year old child?\\
'''Freddy:''' Yes.\\
** Later, in Notepad's [[ExactlyWhatItSaysOnTheTin no-sleep run of Crystal]], despite answering no, Lance ''still'' says exactly the same thing.
* "[[http://imgnook.com/4jS2M And so]] Daisy drank... and drank... all the way to the Pokemon Center."
* The TrainingMontage before the Elite Four match in his Gold run. Also a CrowningMomentOfAwesome.
* Freddy battling Sabrina, [[spoiler: [[Series/SabrinaTheTeenageWitch the Teenage Witch.]]]]
* [[http://img818.imageshack.us/img818/3619/fredwhite8.png I DON'T GIVE A FUCK]]
* [[http://img40.imageshack.us/img40/5511/fred38.png I have two water pokemon!]]
* [[http://imgnook.com/mzl9n Freddy's reaction to first encountering a Team Rocket grunt]] in the Blue Nuzlocke Adventure.

!!!Nonparael's Nuzlocke Runs:
* Ara's Black run introduces quite possibly the best Alder ever: "Do you know who I am? I'm the goddamn Champion. '''FIGHT. NOW.'''"
* Ara discussing with N how to [[http://nonparael.deviantart.com/art/Black-Nuzlocke-26-203548133 "improve"]] the Team Plasma uniform... and [[HardGay what they come up with]].
** "Wait a minute. Something has gone horribly wrong." "Let's never talk about this again."
* [[EvenTheGuysWantHim Ara]] reassuring Cheren of his sexuality... by way of [[MarshmallowHell Bianca's boobs]]. HilarityEnsues.
** [[http://fc06.deviantart.net/fs71/f/2011/149/b/a/black_nuzlocke___41_by_nonparael-d3hjt2v.jpg Here's a link.]]
* [[http://www.deviantart.com/download/202141005/black_nuzlocke___23_by_nonparael-d3cckzx.jpg Eeeeeeeeeeeeeeeeeeeeeeeee]]
* From Ara's Pearl run, we have [[http://fav.me/d2zzqt2 Ara and Cyrus]] [[YouFightLikeACow insulting each other]] through their BossSubtitles.
-->'''Cyrus's Subtitle:''' Galactic Leader seeks [[FanNickname Space]] [[DoubleEntendre Penis]]\\
'''Ara's Subtitle:''' Speaking of which, [[GenderBender how's the space where YOUR penis used to be?]]
* His Soul Silver [[LuckBasedMission "Game Of Chance"]] Nuzlocke is chock full of these. Everything from Edge's behavior to scribbling out Silver's name and writing in "Sugartits" before giving it to the Police Officer.
* Ara learned the hard way that [[http://nonparael.deviantart.com/art/Black-Nuzlocke-38-209053123 hugging a Pawniard]] [[OverdrawnAtTheBloodBank is not the best idea]].
* While in the middle of raiding Team Galactic's Eterna Headquarters, Ara [[http://nonparael.deviantart.com/art/Pearl-Nuzlocke-06-178896654 accidentally stumbles on a group of grunts playing Strip Poker]].

!!! Earl Grey's Ginjika Nuzlocke:
* Diego "Cook" the Quilava [[http://earlgreyxx.deviantart.com/art/PGNC-7-Part-2-278182934 posting in his tumblr about how much he hates Azalea Town]], and then stumbling with a local ScaryBlackMan Ekans, whom he believes has angered about the trash-talking he did about the town. After fighting him, [[http://earlgreyxx.deviantart.com/art/PGNC-8-Part-1-279751108 the Ekans confesses he doesn't like the town either]].
* Cook decides that his team needs a water Pokemon, so when he sees a lone Wooper he sends Audrey the Hoothoot to hypnotize him until K.O., then he and Belmont (the aftermentioned Ekans) carry him away and convince him to join the team.
--->'''Belmont:''' Cook, this isn't going to look suspicious? I mean, [[UnfortunateImplications a black man and a Mexican carrying out a fancy looking white boy-]]
--->'''Cook:''' Nigga, [[LampshadeHanging this is Pokemon, shit like this happens all the time!]]
* Marcel the Wooper is initially silent upon waking (aside from punching out Cook for kidnapping him). When he finally speaks, it's with a [[BadassBaritone deep, accented voice]], justified by his smoking habit but still [[VocalDissonance distinctly unfitting for a fourteen-year-old]] (or a [[RidiculouslyCuteCritter Wooper]]).
--->'''Cook:''' *laughing* That gringo sounds like [[WesternAnimation/LooneyTunes Pepe Le Pew!]]
--->'''Marcel:''' [[DeadpanSnarker I am beginning to regret this decision already.]]
* [[http://earl-greyxx.deviantart.com/art/PGNC-11-Part-2-317159884 In the middle of this update,]] in between Diego training with and taking pride in his new teammates and a dramatic glimpse into his backstory, is a scenic view of his old home with a beautiful night sky... and [[MoodWhiplash the stars are spelling out "DICKS"]].

!!!Manic's Screenshot Runs:
* [[KickTheSonOfABitch Rayquaza turns Archie and Maxie into bloody smears on the ground after it gets Kyogre and Groudon to calm down in Derpy Emerald.]] [[AssholeVictim Manic and his party do not care in the slightest.]]
* In Fatal Platinum, how does our protagonist keep Lucian out of his mind? By conjuring up mental images of the most grotesque, hilariously vile things he can think of. The only thing specifically noted is "Pichu/Miltank pairings," but... well. And then when Lucian tries to read his Medicham (who has been a serious character throughout the run):
-->'''Lucian:''' Brrrr...let's see what you have in YOUR mind instead. A fellow psychic would never-
-->'''Diell:''' Hippowdon lapdance.
-->'''Lucian:''' OH COME ON!
* Manic tearing down the Voltorb Flip mini-game in Spirit Electrum to get thousands and thousands of coins, and the team's proceeding reactions.
-->''*Manic advances to Lv. 7 of Voltorb Flip*''
-->'''Link:''' ''WHAT THE FUCK.''
-->'''Manic:''' What? It's easy.
-->'''Will:''' The old guy is staring at you like you've got a tree growing out of your head!
-->'''Gail:''' It's only a matter of time until you make a ''fatal'' mistake!
-->'''Link:''' Ha! Gail's right. I mean, sure, you got this far, very nice. But this is the ''maximum'' level. There's no way you can-
-->''*Manic clears Lv. 7 as well*''
-->'''Link:''' What ''are'' you?!
* During Blinding Light, Mccoy the Escavalier sweeps Marshal while doing a hoedown. Which is funny in itself, but this tidbit stands out.
--> '''Zerzan:''' I can't believe this is working.
--> '''X-4:''' He'd probably stop if Vile told him to. Vile?
--> '''Vile:''' Yee Haw.
--> '''X-4:'''Well, okay then.
* Once Manic reaches Goldenrod City in Argent Ante, he eventually returns to Voltorb Flip. The reactions are gold, especially Manic's complete nonchalance about it.
--> '''Velvet:''' You've won...more than ''ten thousand coins'' in an hour?
--> '''Manic:''' Yeah, I had a few setbacks. Unlucky picks, things like that. I can still afford a nice TM, though!
--> '''Alli:''' Uh, this guy looks ready to shit enough bricks to build a house. Maaaaybe we should call it quits for now?
--> '''Manic:''' Hmmm? Yeah, I guess so. See you around!
--> '''Voltorb Flip Guy:''' Please, I have a family!
* And in Full Circle, when Manic needs to choose a game to win May's soul back from Giratina, he chooses... [[spoiler: Voltorb Flip, naturally]].
* For the Sacred Spectre [=Q&A=], two people decided to ask a question to Nate, the boy [[BodySurf Manic was inhabiting during this run]]. The answer given?
--> ''*beep beep beep* We're sorry, the character you're trying to reach has been disconnected or is no longer in service. Please check your number and dial again.''
* In 'Dark Stars', Manic realizing he was put into this Sinnoh as Sophie's Chimchar...and then squeeing over the fact he is an Adamant Chimchar with Iron Fist. Then Manic gives us this gem when learning Ember:
--> '''Manic:''' Nice!
--> '''Sophie:''' You learned a Fire attack! That's great!
--> '''Manic:''' Hang on, I want to try something.
--> '''Sophie:''' We really should get home, Manic...
--> '''Manic:''' It'll only take a second, I promise!
--> '''Sophie:''' All right, just a second.
--> '''Manic:''' Let's see here. Strike the pose, move the hands like so, and...(Picture of [[StreetFighter Ryu firing a Hadouken is shown]])
--> '''Sophie:''' What does Hadoken mean?
--> '''Manic:''' Oh nothing important. ''[[NotSoAboveItAll Yessssss...]]''
** Then on the throes of his BigDamnHeroes against Maylene's Lucario:
--> '''Manic:''' [[RapidFireFisticuffs *Uses Close Combat*]] [[FistOftheNorthStar YATATATATATATATATATATATA!!!]]
--> '''Cyrano:''' MOTHER OF ARCEUS!
--> '''Maylene:''' Holy-
--> '''Sophie:''' WOW!
--> '''Manic:''' [[YouAreAlreadyDead Omae wa mo shindeiru.]]
** And again against Byron's Aggron:
--> '''Manic:''' Mind if I double down on this one?
--> '''Sophie:''' Manic? Sure, go ahead.
--> '''Manic:''' I think I can make this at least a little interesting.
--> '''Sophie:''' You can? I'm all for that.
--> '''Manic:''' Just a bit of stick-and-move...that's right, big guy, follow the leader...
--> '''Byron:''' Your Infernape is getting into close range with my Aggron on purpose? He's brave, I'll give him that, but-
--> '''Manic:''' ([[{{Shoryuken}} Uses Sky Uppercut]]) SHORYUKEN!
* During Manic and Lance's first match in Spirit Electrum, Lance boasts that no one in Manic's party has the power to stand up to his Charizard. [[JerkassGods Anemoi]] is having none of it.
--> '''Anemoi:''' EXCUSE ME.
--> '''Manic:''' Hey, what're you doing with Lana's pokeball?!
* When Proton is reencountered during Manic's Radio Tower raid in Spirit Electrum, Manic and his party make it very clear how little a threat Proton poses to them:
--> '''Manic:'''Let us pray the pimp's prayer.
--> '''Grace:'''Lord, please pray for the soul of this bitch.
--> '''Rebbeca:'''And guide my p-pimp hand and make it strong, lord!
--> '''Link:'''So that she might learn a ho's place!
--> '''Kenya:'''Amen!
--> '''Farrah:'''Amen.
--> '''Manic:''' *SMACK!* Now stay down!
* Edge realizing in Spirit Electrum that Mt.Silver isn't actually a mountain of silver.

!!!Kynim's Runs
* Ky-nim's Diamond run was full of funny moments, most of which involved either [[{{Keet}} Hai]][[CampGay si]] or Team [[Music/LadyGaga Gaga]].
** "Behold... [[PhysicalGod DIALGAGA]]."
* [[http://ky-nim.deviantart.com/art/Nuzlocke-White-003-208803217 Seeing N in Accumula:]]
-->'''N:''' [[ComicBook/TheCreeper Hi...y-your Pokemon...did...did you know...he talked...and...you're pretty.]]
** [[http://ky-nim.deviantart.com/art/Nuzlocke-White-004-209404725 The fight that ensued after that meeting]]
** [[spoiler:This unfortunately becomes a FunnyAneurysmMoment after [[StableTimeLoop Nina talks to a young N]].]]
* Any scene with [[CampGay Burgh]] and his [[{{EverythingsBetterWithRainbows}} Rainbow Aura]]
-->'''Burgh:''' Grab my scarf!
* [[http://ky-nim.deviantart.com/art/Nuzlocke-White-020-286825549 The N Ferriswheel scene]], which most Pokemon fans chalk up as romantic but the scene is anything but that.
* In the middle of Part 38 of her White Run, Alder is hosting a conference among the Gym Leaders. Good luck trying to take it seriously since [[CampGay a certain someone's]] [[BattleAura rainbow-colored aura]] [[http://www.deviantart.com/art/Nuzlocke-White-038-427936451 is hard to ignore]]
* [[http://ky-nim.deviantart.com/art/Nuzlocke-White-VS-CAILTIN-AKA-APRIL-FOOLS-600269181 This April Fool's gag]]--N and Nina...as [[spoiler:MAGICAL GIRLS]]. That is all. Also the author steps in personally to stop the whole thing from getting too ridiculous. Also-also, it turns out to all just be a dream that Elite Four Caitlin was having. ALSO-also-also, ''it's technically canon'', as Caitlin references the dream at the end of her and Nina's battle!
* After leaving us on a month long cliffhanger of Zach about to be zapped to death by N's Klinklang, Ky-Nim returns us to the action...and Jojo defeats said Klinklang with no effort at all before giving N's Vanilluxe an OffhandBackhand. We should probably be more angry, but most of us are more glad that Zach's okay.

!!!Nuzlocke: The Gold Standard
* The sheer amount of LampshadeHanging, in general.
** And Mike and Silver's snark-offs.
--> '''Silver, angrily:''' ''Ha. My sides split. Donít you just think youíre the funniest?''
--> '''Mike:''' ''I try not to challenge public opinion too much.''
* Within the first real scene it refers to Mike's great FetchQuest, which is struck out and replaced with '[[GottaCatchEmAll epic journey]]'.
* 'Any minute now a bird outside is going to start tweeting a counter-melody, and when that happens there's nothing left but for The Author to get out Pokemon Platinum and hope that a new run turns out better this time.'
* Professor Elm's unseen but highly scientific research, which involves an electrical buzzing, a lot of shouting and 'the unmistakable noise of something being hit repeatedly against a table edge', which leaves the floor and walls burnt and steaming when Mike enters.
* 'In that case, my starter will be Kingdra-'
* The scene with the police back in Elm's lab after they were robbed.
** And then the scene with the Pokemon-catching-tutorial lady. 'I-AM-NOT-SHOUTING. I-AM-TALKING-IN-CAPITALS-AND-DASHES. THERE-IS-A-DIFFERENCE.'
** 'Run'.
* 'No combination of vowel sounds can do full justice to the noise Mike's mum made on meeting his starter. It included noises only recognised by small furry animals.'
* (''[[YouDoNotWantToKnow The description of the move Leech Life has been removed in the name of common decency.]]'')
* Elm's request when handing over the Egg, turned into a cosmic feat of awkwardness. 'You want me to be its ''mother''?'
--> '''Aide:''' ''Oh, well now, it's not quite like that-''
--> '''Mike:''' ''How'' isn't ''it?!''
** The Egg generally seems to be a very good source of innuendo, such as the scene where it hatches.
* Upon arriving in Goldenrod City, Mike's team proceed to blow all his money on all the many attractions. In the form of a music parody, to the tune of Lonely Island's 'Japan'.
** Which then comes back to bite Sammy and Kate, when the Miltank Mike catches outside Olivine City turns out to be the same one as the one they dunked in the river back in Goldenrod.
* Zach mistaking the voices of his team members for the summons of Arceus, which then gives him the impression on hearing them argue with each other that the Poke-God is having an identity crisis.
* In [[Literature/TheHungerGames the seventy-fourth annual Bug-Catching Contest]], Mike lures out a Scyther by hanging one of his team members up as bait and then as soon as one shows up dump-tackling it and wrestling it himself. Made funnier by Archie's CaptainOblivious mutterings about general unfairness of life [[FunnyBackgroundEvent as behind him his trainer]] [[MeaningfulBackgroundEvent fights a giant preying mantis monster with his bare hands.]]
* [[FourthWallObserver Harry the Sudowoodo.]]
* 'Nameís Bill. PC designer, professional Pokemaniac. I proved recently that the Internet is a series of tubes.'
* Upon Kate's evolution into a Fearow
--> 'What? Never seen a bird with a mohawk before?'
* Mike's total inability to navigate either Morty or Pryce's Gyms.
* Nikki's excitement at the thought of meeting pirates on the open seas, never having left Union Cave before. Even the fact that there are none doesn't dissuade her.
** And then she squees at the sight of the Red Gyrados while everyone else is panicking.
* The AllNaturalSnakeOil Cianwood medicine.
* 'What do you want me to do with this, eat it?'
* Colin does some late-day grinding to evolve into the Espeon he's wanted to be for the last five chapters. He does evolve... but he misses sunset by thirty seconds and becomes an Umbreon. The BigNo and sheer sense of karmic backlash make it.
* After catching a Girafarig from a nearby route, Kate tells Mike that 'you need another Normal type like you need a hole in your head. I could provide you with either of those if you ask.'
* The DressingAsTheEnemy sequence. All of it. When Mike sends Solenoid to steal a Team Rocket uniform for him, he forgets to specify a ''male'' one. This leads to everyone from the Executives to the Director to his rival all being very surprised and worried to see him attempting to rescue an entire city in a black skirt and short top. In the end he just gives up and says 'It's one of those kinds of days'.
* The Director's IAmVeryBritish speech style.
* Perish Song, it turns out, is a RickRoll.
* Karen's somewhat romanticised depiction of the Dark-type being completely ruined by the existence of, well, [[{{Jerkass}} Colin]].
* When Mike goes round his team after the Championship battle and tells them how much he values them and their committment, when it comes to Colin he just bluntly tells it as it is - Colin is a dick that he can't stand. Colin replies that he appreciates the honesty.

!!!Jet's Black Nuzlocke
* [[HotBlooded Cheren's Oshawott]]. Just...Cheren's Oshawott.
** Bianca's Snivy, too.
* Tepig's reaction when Jet decides to name him "Sir Francis".
* [[http://jetsblacknuzlocke.com/comic/episodes/ep002.html "Snivy...used...]]'''''[[DeathGlare LEER!]]'''''"
** When Jet's mom sees what a mess the battle made: "Mom...used...'''''[[TranquilFury LEER!]]'''''"
** Professor Juniper finds it hilarious too! And she proceeds to ''throw'' Pokeballs and Pokedexes at them.
* N's first meeting with Jet. Her hair reminds him of his Zorua and he ends up having a flashback to her. Fade back to the present and N is ''absentmindedly petting Jet's hair'', much to Jet's (understandable) confusion and discomfort.
* While Jet and her ever growing team is traveling, [[http://jetsblacknuzlocke.com/comic/episodes/ep005.html we get this story's explanation for the NPC who informs you of ledge jumping.]]
-->'''NPC:''' (''wearing a monocle, mustache and tophat and holding a cane'') Hey, check this out! (''jumps ledge'')\\
'''Jet:''' [[MundaneObjectAmazement Amazing!]]
** Before that, Lilly the Lillipup leaps to hug Firedog the Patrat to welcome him to the team, only for him to push her aside.
* Oshawott's reaction to losing.
* Broccoli the Pansage ''[[CowardlyLion failing to show up for his first gym battle]]''. When he returns, [[TeamMom Lilly]] gives him an angry smack for abandoning them...[[SugarWiki/HeartwarmingMoments and then hugs him for coming back]].
* Chili turns out to have slept through the first gym battle.
* When Jet meets N in the Pinwheel Forest, she tries to guess his name by essentially reciting the entire alphabet.
** Additionally, she had gotten separated from her Pokemon, who are all searching for her at that point.
** Poor [[NotGoodWithPeople N]] [[NoSocialSkills mentally agonizing over what he should say to her]]. Jet picks up on this, telling N that he should relax a bit.
* N's FailedAttemptAtDrama in Route 4. He's about to walk away all cool and mysterious-like...and then he faceplants into the sand.
* In order to get Percy and Val out of prison to help her speak to N, Jet agrees to do all sorts of community service for Clay. It eventually culminates in Clay having Jet make him a sandwich and she's ''just about to finish doing so'' when she realizes that he's just taking advantage of her at that point.
** Shortly afterward we get her battling Clay--what follows is the ''funniest Nuzlocke death ever'': [[spoiler:No one ''actually'' dies--Jet sends Tutu out to fight Clay's Excadrill, the Excadrill glares angrily at Tutu...and Tutu proceeds to pack up a suitcase, put on a hat, salute Jet and fly out the nearest window]].

* Kindle demonstrates that he just learned Smokescreen - by using it on Rooke.
* Scout the Sentret vs Granite the Geodude. Being used to OHKO-ing things, Scout gets increasingly angry with all the many Scratches he has to do - and Granite's total obliviousness just makes it better.
* Scout also bashing a poorly-drawn Hoppip out of the air as part of a training montage.
* Rooke's TakeAThirdOption approach to Bugsy's Gym puzzle.
* Battles that were quick in the game tend to be done quickly and humourously in the comic, but special mention goes to Granite's two-panel OHKO of Vincent's Zubat in Azalea.
* Ilex Forest is one big series of events designed to terrify Rooke. This might be the [[PlayedForLaughs funniest]] depiction of TraumaCongaLine ever seen.
* As soon as Rooke drops Cara the Drowzee and Lacy the Rattata off in the Day Care:
-->'''Cara:''' ''So... Lacy, right?'' (Grins) ''Let's talk about boys.''
* Rooke celebrates getting Kai the Dratini with a ''Film/TheLionKing'' homage - on the roof of the Game Centre.
* Boss the Butterfree is a pint-size badass. And he knows it. It gets even better after he gets the TM for what became his SignatureMove - Hyper Beam.
* Kito the CasanovaWannabe Vulpix entering the comic to the tune of "Sexy Back".
* Ojo the Magnetmite/ton's excessive jitteriness.
* When Rooke gets to Olivine Lighthouse, she encounters some stoppage points:
-->'''Sailor:''' ''Hey, welcome to the lighthouse! We should battle!''\\
'''Rooke:''' ''Uh, no thanks, I actually just wanted to go see if I could help the sick Poke-''\\
'''Sailor:''' ''NO. BATTLE.''

* From Dennis's Revenge: The Johto Takeover:
-->'''Falkner:''' Dennis, why do you seek to fix what Arceus ([[spoiler:who is masquerading as Silver]]) has done?\\
'''Dennis ([[spoiler:actually Genosect in human form]]):''' Look at this place! Legendaries all over, level 3 fully evolved Pokemon, even Pokemon that don't belong in their regions are here! And you still have your two derps!\\
'''Falkner:''' You did NOT just call my precious birds [[InherentlyFunnyWords DERPS]]! I'll take you down! Go, Pidgey!
* In Lenni's white run, [[http://fc00.deviantart.net/fs71/f/2011/099/6/d/a_really_stupid_comic_part_2_by_thewickedkid-d3dmtne.jpg when Nel's sewaddle evolves.]]
* Azer's run has at least one in every page... but a combination of the earlier image of Godzilla (a charmeleon) hugging Azer and the later statement "He likes hugs" takes the cake for this troper.
* In Aouli's run, Canterbury the Butterfree explains to the protagonist what "flashing" is. And no, not the HM move.
* Pencil's Leaf Green Nuzlocke [[http://yoroshii.deviantart.com/art/Pencil-Nuzlocke-pg6-204571692 Drunk Dallas makes everything better]]
* Azza's [=LeafGreen=] run at the beginning of [[http://wonksbrother.deviantart.com/art/Azza-s-Nuzlocke-Run-Arc-1-08-190437579 comic 8]], when Jasmine the Jigglypuff joins the party:
-->'''Jasmine:''' (using Sing) [[Music/{{Kesha}} I wake up in the morning feeling like P-Diddy...]]\\
'''Azza: ''NO.''''' [[TakeThat Learn real music.]] (puts a pair of headphones on Jasmine)\\
'''Jasmine:''' What the... (music starts blasting, Jasmine becomes stunned)
** In [[http://wonksbrother.deviantart.com/art/Azza-s-Nuzlocke-Run-Arc-1-10-192754573 comic 10]], during the training.
--->'''Minge:''' LEARN SOMETHING, DAMMIT!!!\\
'''Esther:''' Ow! Ow! Ow!\\
''Esther learned something!''\\
'''Minge:''' See? There is no problem that can't be solved by hitting it until it does something you want.
* In Oh Gosh, Platinum Nuzlocke, naming a psyduck "Implying I."
-->Implying I used water gun. Implying I grew to level 18. Implying I can't learn more than four moves. Implying I forgot how to use tail whip. Implying I learned confusion!
-->'''Oh Gosh:''' That was amusing. *boxes Implying I*
* [[http://land-walker.deviantart.com/gallery/#/d4b3t14 Why its probably okay to have the No Dupes rule on, after getting 5 of the same damn thing, you are like a derp magnet.]] And yes, there is a facepalm.
** [[http://land-walker.deviantart.com/art/Yellow-Nuzlocke-part-9-262735383 The following comic]] provides possibly the ''best ever'' interpretation of a Diglett's body underneath the soil. It must be seen for itself, to describe it would be to spoil it.
* Urahara's Scorched Earth Nuzlocke:
-->(after nicknaming a Skiploom Deedeelion)\\
'''Verona the Mismagius:''' [[SarcasmMode You're the most creative person.]]\\
'''Jasmine:''' Shut up. Or do you want me to rename you oldladyhat?
* In Infecting the World: The Ultimate Bug Monolocke, ZP's opinion on Victory Road's boulder puzzles:
-->"It's like there are magical fuck-you gnomes that want to make your day miserable."
* Golden Bells has a very funny prologue. Starts off serious, with a text about the challenge, all while [[http://fc09.deviantart.net/fs70/f/2012/221/4/2/gb__prologue_by_inkypaws_productions-d5ai5k0.png the protagonist is being dragged by her starter.]]
* French's FireRed nuzlocke features [[http://i14.photobucket.com/albums/a317/french-teapot/Page14.jpg Wilton the Gloom. Talking his way through the Cerulean Gym]]
* [[http://cheezburger.com/6796993024 This guy]] makes the best of a bad situation.
* In Nix's Nuzlocke, Quinn [[FreakyFridayFlip switches bodies with Bill]] and immediately turns on him. When they switch back, she [[CrossesTheLineTwice makes a]] [[IncrediblyLamePun beeline]] for him, but is stopped by Amazon's Stun Spore.
** Quinn in general for her [[SirSwearsALot foul mouth]] and any swears she utters being [[SoundEffectBleep replaced with a bee buzz.]]
** '''''[[http://nixnuzlocke.smackjeeves.com/comics/1753464/no-service/ WHAT THE HELL IS THIS.]]'''''