* "[[{{Narm}} WATCHU DOIN' MOTHAFUCKA?!]]"
* Second half of Chapter 7.
** Also, Chapter 9, after being covered in sewage waste. Watch as your foe reacts in revulsion as you approach him; plus points go to players who decide not to change Vito's soiled clothes before returning to their boss.
*** Vito will get complaints about his smell, [[FridgeLogic regardless of when he changes.]]
*** "Argh...if [[spoiler: Luca]] just stopped by to pick up some steaks, I'm gonna kill somebody."
*** "What is this, Captain Shitbag to the rescue?!"
* Joe and Eddie drunkenly singing along to Dean Martin's "Return to Me".
** "Oh shit...I don't know the [[PrecisionFStrike fuckin']] Italian...words!"
* Radio news about "new" and "future" things, like credit cards, mobile phones or takeaway food.
** And the exchange about the idea for video games between two guards in the first stealth mission.
** To say nothing about hypocritical humor when it comes to effects smoking has on health and Richard Nixon being described as "trustworthy".
* The gameplay stats keep track of how long you've stared at the Playboys as "Time spent on Playboy [[IReadItForTheArticles articles.]]"
* It's fully possible to kill the gun shop owner as he tries to threaten you with a BadassBoast.
--> "Don't be a dumba-[[KilledMidSentence BANG]]"
* Joe's brilliant idea for disguises: mustaches. Even funnier is just before they get to the disguises, Vito is genuinely surprised by Joe's intelligence.
** Also even more funny is afterwards when Henry is asking Vito if he was involved was the hotel bombing, Vito tries to deny it, then Henry reveals he knew Vito was involved the whole time by ragging on his cheap disguise.
* "[[https://www.youtube.com/watch?v=Oa07L8Xwhg8 You drive like my fucking grandmother, you know that?]]"