* Egon has quite a few geeky hilarious lines. To wit, after being slimed?
--> '''Egon''': Ugh, disgusting...but not ''entirely'' without scientific interest.
** Also:
--> '''Egon''': Normally, I find exposure to mold...stimulating. [[EveryoneHasStandards But that was a bit much.]]
* Ray's [[RunningGag mounting frustration]] from being constantly shushed by [[OldShame The Grey Lady]].
* Towards the end when there is a TV report about a ghost attack at the Thanksgiving Day Parade. The TV has been knocked on its side and is shown as such. There is a quick cut to the team watching it with their heads turned sideways to see it. Why is it funny? [[spoiler:Because you the player most likely have your head turned the same way as them.]]
* You and the other guys have defeated the Juvenile Slor and escaped the crumbling Shandor Island within seconds of its total collapse. Ray starts excitedly asking about what you just defeated, only to be glared at by the rest of the team - especially Egon.
--> '''Egon''': SHUT UP.
* When the elevator at the Sedgewick temporarily stops-
-->'''Peter''': "Think we're stuck", well let's see... ''leans towards panel, presses a few buttons (and appears to miss a couple times)'' Think we're stuck, think we're stuck, think we're stuck... Ray, uh, you guys okay with officially stuck in the elevator? Show of hands?
-->[''Rookie raises his hand'']
** And-
-->''Peter, Ray, and Rookie get ready for Slimer. Cut to the elevator doors.''
-->'''Peter''': Kill it, Ray!
-->''Egon opens the elevator doors.''
-->'''Egon''': Need a hand?
-->'''Peter''': You always fail me, don't you?
** Arguably the funniest thing about this scene? Egon is strong enough to pry apart stuck elevator doors with his bare hands!
* When the Sedgewick hotel floods with ghost seawater ([[ItMakesSenseInContext it's a long story]]), a starfish latches onto the back of your proton pack and slides around.
* One of the Cursed Artifacts you find is a pair of bellbottom pants. Description: ''These pants keep on truckin' - WITH NOTHING IN THEM.'' Extra points for disco music when you pick them up. It gets even better when you make it back to the firehouse and find that the pants are [[spoiler: not put away somewhere like the other artifacts; they follow you around.]]
** Another Cursed Artifact- [[ProductPlacement Ghostbusters]] [[NoFourthWall on DVD.]]
*** The story behind the artifact: The Cult of Gozer attempted to recover artifacts from the future so they could determine the outcome of their plan...and the DVD was the only thing they could find.
* Some of the answering machine messages:
-->'''Answering Machine''': Dr. Spengler, this is James from We Ship It. Listen, you gotta come down and pick up this package of Carpathian Dunnbach[?] mold we've been holding for you. It's started to spread, it's taken over half the loading docks, and I ''(pause)'' I think it's ''singing''?!
* Ray speculating on what the other mood slimes react to:
-->I wonder what their purpose is, what they would react to? Happiness, sadness, anger, sunlight, moonlight, orbital convergence, shooting stars, prayer, screaming, candles, spotlights, [[ArsonMurderAndJaywalking diet or regular]]... the possibilities are endless!
* One of Janine's many phone conversations:
--> '''Janine''': Ghostbusters. ''*pause*'' No, we do not recommend you attempt to perform a level 5 Peruvian exorcism on yourself. ''*pause*'' But after you've tied yourself up, it would be incredibly difficult to do that to the cat, even if you could catch it.
* Vigo's painting has [[http://ghostbusters.wikia.com/wiki/Vigo#Ghostbusters:_The_Video_Game_2 many funny things to say]] (voiced by [[Creator/MaxVonSydow the original voice of Vigo]], no less!).
--> "I should have had a bathroom painted in this thing."
--> "Pull my finger. I command you."
--> "I dreamt I was in a painting with ponies. It was nice."
--> "Did you know that the human large intestine, when stretched out, will wrap around a city block? You have to get a running start."
--> "I see the evil of the times to come. You will remember paying $1.45 for gas and will weep hot tears for yesterday."
--> "I see the evil of the times to come. [[IWantMyJetpack No flying cars - EVER!]] [[EvilLaugh HAHAHAHAHAHA!]]"
--> "I see the evil of the times to come. [[Creator/OJSimpson The glove won't fit.]]"
--> "I see the evil of the times to come. [[DigitalPiracyIsEvil In time all music will be free, but for the cost of your soul.]]"
--> "I see the evil of the times to come. [[TakeThat You will choose a king far more evil than myself to rule you. Twice!]]"
* After you defeat the Stay Puft Marshmallow Man, the answering machine at the office gives us this little gem:
--> "I was wondering if it's safe to eat all this marshmallow goo that's fallen over my balcony. And as a followup question, what if I already did?"
* Another one from Janine:
--> '''Janine''': Hello, Ghostbusters. No, we do not summon the ghosts of dead relatives and then capture them so you can ask them the combination to the safe. Same to you, pal.
* Ray and Peter discussing the restraining order that the maid from the first movie had put on them - just in time to rack up another.
-->'''Peter:''' [[DeadpanSnarker Nice, now we got another plaintiff.]]
* Peter chastising the Rookie for accidentally falling over the side of the building - leading into the Stay Puft boss battle - saying his insurance hasn't been paid up yet.
-->'''Peter''': Hey, Ray? Say three guys, the size of your finger, knocked you off a ''30-story building'' and you had to climb alllll the way back up to tear 'em apart... how mad would you be at those three little... dinky types?
-->'''Ray''': [[ThisIsGonnaSuck I'd go with "mighty pissed".]]
* And this, from the same mission:
-->'''Ray:''' ''*softly*'' "Stay quiet. Be careful not to make any sudden movements..."
-->''*Mr. Stay-Puft's hand crashes through the wall*''
-->'''Ray:''' "AHH! Sudden movement! [[BringMyBrownPants SUDDEN MOVEMENT]]!!"
* During the Times Square mission, Ray calls for backup in the form of Peter.
-->'''Ray:''' Venkman. Come in please! Pandemonium up here! Chucks of the building missing everywhere! You are required at the site now!
-->'''Peter:''' So happy to be of demand, but these sugar balls have got me nailed down! I can't get pass them. They're disgusting! And they're unhealthy!
-->'''Ray:''' Uhh, did I mention that there is a spectacularly beautiful lady in distress?
-->'''Peter:''' [[TheCasanova I'llberightthere.]]
** Prior to this, when Ray tells Peter to distract Stay Puft, he finds out that the latter is getting coffee. And in the stylized version, we see Peter drinking said coffee while sitting on the stairs!
* After the library level, there's a message left for Ray on the answering machine. He owes approximately 418 dollars in late fees. Gets funnier when you adjust it for inflation. That 418 bucks in 1991? Over ''$730'' in 2014 dollars!
* Another funny elevator scene during the Times Square mission-
-->''elevator opens and two men peek out, seeing Ray and the Rookie.''
-->'''Man on right:''' All full! Going up! ''frantically pushes a button to close the doors'' He uh...just passed gas! Catch the next one!
-->''Ray blocks the doors with his foot, then steps in with the Rookie.''
-->'''Ray:''' Relax sir, we handle foul vapors all the time.
** And-
-->''elevator shakes on the way up.''
-->'''Man on right, glaring at his partner:''' 'Let's stay in for lunch,' you said. 'Why leave the building?' you said. 'It'll be quiet,' you said...You know you're fired.
-->'''Man on left:''' You're right. I secretly knew our lives would be endangered and thought 'Hey, I'll make sure I trap Mark with me inside an ELEVATOR!'
-->''alternate between Ray's and the Rookie's expressions while this is going on.''
-->''elevator arrives on floor.''
-->'''Ray, on exiting:''' Excuse us.
* When Ray gets possessed (again) and starts speaking in tongues over the walkie-talkie during the Museum level, the other Ghostbusters just tell the Mayor to keep an eye on him while they went and dealt with the bigger problem. They aren't even slightly perturbed. How often does Ray get possessed, exactly?
** Quite often, since it's almost a running gag in game.
* Egon remarks with astonishment that [[ReadingsAreOffTheScale the PKE readings are off the charts]]. Then he remarks with annoyance that now he's going to have to make new charts.
* When exploring the Central Park graveyard, Winston remarks that this isn’t the Central Park he’s used to.
-->'''Egon:''' You still have your wallet?
* The fact that Egon, of all people, gets the PreMortemOneLiner during the final battle.
-->'''Shandor:''' [[AGodAmI I AM A GOD!!!]]
-->'''Egon:''' [[BlasphemousBoast We eat gods for breakfast!]]
** And this later discussion makes it even funnier.
-->'''Ray:''' "We eat gods for breakfast"?
-->'''Egon:''' Too much?
-->'''Ray:''' ''[beat]'' I liked it.
* Near the end of the game, Winston figures out and summarizes Shandor's entire plan and his actions throughout the game:
-->'''Shandor''': Very good! And they say you're the slow one!
-->'''Winston''': Wait, what? Who says that?!
-->'''Peter''': [[BrutalHonesty Everyone]].
* One exclusive to the stylized version, at the beginning of the Marshmallow Man chapter. It's a completely silent exchange as Ray, Peter, and the Rookie sneak into the building Stay Puff is smashing, with Ray giving the other two an increasingly silly set of hand signals, and Peter just sighing and shaking his head at it.
* At the beginning of the game, where Slimer manages to escape containment:
-->'''Ray:''' Look out! Slimer's escaped!\\
'''Peter:''' ''(deadpan)'' No, wait. Come back.
** Even better is that sometimes he'll just walk over to the arcade machine.
* At the very end, the others let the Rookie decide if they should free Peck. He does... by shooting him down, making Peck fall flat on his face.
* During the first visit to the Sedgewick, Venkman insists on staying nearing the elevators. Slimer still slimes him, anyway.
* The ballroom at the Sedgewick is stated to be reserved for a bar mitzvah, but you can find a huge ham hock on the buffet table. In the remaster, you can disintegrate this ham to get an achievement, "Kosher!" with the description: "Remedy a dubious food choice to make the bar mitzvah as orthodox as it can be."
* Speaking of achievements, you can get the "Total Protonic Reversal" achievement for [[AchievementMockery blowing yourself up]] with a Boson Dart. It will also unlock if you [[SchmuckBait cross the streams]] for long enough... complete with ''another'' instant knockdown.
* The various upgrade descriptions are hilarious, full of FalseReassurance and notes about the extremely dangerous nature of the Ghostbuster's equipment.
** Egon offhandedly mentions during the tutorial that the automatic overheat reset prevents the pack from exploding with "the force of several atomic bombs".
** The Boson Dart will vaporize a 3 mile radius if the emitter wand is blocked when firing, while the upgraded variant reduces this to a [[FalseReassurance mere 1 mile]].
** The upgraded Shock Blast can sometimes emit particles that effect the user's mental state, resulting in "an elevated intemperance and an increase in general wantonness"[[note]] Perhaps a nod to how fun it is to [[DieChairDie blast objects]] with this weapon in particular[[/note]], and light from the heat dispersal upgrade's vents can cause temporary blindness, the listed solution to which is not looking at it.
** The order-reversing particles used by the upgraded Stasis Stream can cause numbness in the fingers and hands and also "fleeting feelings of ennui, angst and boredom-laced paranoia". A disclaimer is also given that they "affect the user's gender in no discernible way".
** One of the Slime Blower's upgrades was derived from something in Egon's fungus and mold collection. It also causes the slime to sporadically regain the "emotive properties" of the pink slime from the second film, causing the upgrade screen to advise you to disable the system in the presence of loud music (thankfully, none is encountered in-game).
** The other slime blower upgrade blasts the slime with a low-level proton stream. The resulting increase in operating pressure [[FalseReassurance "will most likely not result in a Plasm Tank rupture"]].
** Upgraded slime tethers have been known to malfunction and tie the user's legs together. The flash-heating applied to upgraded tethers also apparently improves their taste, though it also discourages you investigating this yourself.
** Exposure to an upgraded Meson Collider causes sterility in lab mice, but "its impact on humans remains debatable".
** An upgraded Overload Pulse is apparently strong enough to rip small holes in the barrier between this world and the next. The upgrade page entirely brushes past the consequences of this, and instead tells you not store things or dispose of trash in them.
** Both of the upgrades for the Ghost Trap involve dismantling parts of its safety features in the name of faster trapping. The end result is an entirely unshielded trap that also periodically vents plasma from the air intakes when in use, though apparently the only negative effect of this is singed carpet.
* After his colleagues [[MomentKiller interrupt a moment between him and Illysa,]] Venkman whines:
-->''Why don't you all go away??''
* When Stay Puft Marshmallow Man is wrecking havoc in Times Square:
--> '''Ray''': It wasn't me this time, I swear it.
* To the left of the arcade machines on the second floor, there is an Employee of the Month board, filled through October (the game takes place at Thanksgiving). Peter is the award winner every month.....except July where Winston took the honors. Funny at first glance, even funnier when you try to figure out all the questions this raises. Did Peter set up the board himself only to have Winston troll him? Or does Venkman have HiddenDepths behind his slacker persona not seen by the audience and he really did win legitimately nine out of ten months with Winston beating him out fair and square in July?
* An EasterEgg involving a computer on the second floor of the Firehouse; it displays the [[AWinnerIsYou infamous end screen]] of the ''[[VideoGame/Ghostbusters1984 Ghostbusters]]'' [[UsefulNotes/NintendoEntertainmentSystem NES]] game: "[[JapaneseRanguage CONGLATURATION !!!]] YOU HAVE COMPLETED [[BlatantLies A GREAT GAME]]. AND [[MakesJustAsMuchSenseInContext PROOVED THE JUSTICE OF OUR CULTURE]]. NOW GO AND [[WantonCrueltyToTheCommonComma REST OUR HEROES]] !"
* During the cutscene where Ilyssa activates the pillar at the museum, one of the freed possessor ghosts takes over Peck... and makes him start dancing.
** One of the first things you'll end up doing after regaining control of the Rookie is sliming Peck.