* While the movie generally avoids overly-easy RuleOfFunny, it still manages to earn more than its fair share of spit-takes, even from people not actually drinking anything at the time.
* The shower scene, where [[spoiler: Tom and Summer watch a porno and decide to try out one of the positions they saw in the shower. It doesn't work out very well.]] Funny enough as it is, but the fact that [[spoiler: we don't actually see the position]] makes it hilarious.
* ''"I HATE THIS SONG!"''
* The greeting card a broken Tom writes after Summer leaves him: "Roses are red, violets are blue... Fuck you whore".
* Tom's blind date. Drunken karaoke singing is always hilarious, but Gordon-Levitt's especially good at it.
-->'''Tom:''' And then she took...a giant ''SHIT''...on my FACE! ...LITERALLY!
-->'''Blind Date:''' ...Literally?
-->'''Tom:''' ...No, not literally, gross--ew, what's the matter with you?
* "Darling . . . I don't know how to tell you this, but... there's a Chinese family in our bathroom."
-->'''Paul:''' Look, maybe she was just having a bad day.
-->'''Mackenzie:''' Yeah, maybe is was--was some sort of... hormonal thing.
-->'''Tom:''' What do you know about PMS?
-->'''Rachel:''' [[DeadpanSnarker More than you, Tom.]]
* The very first thing that appears on the screen:
-->This is a work of fiction. Names, characters, places and incidents either are products of the authorís imagination or are used fictitiously. Any resemblance to actual events or locales or persons, living or dead, is entirely coincidental.
-->Especially you, Jenny Beckham.
* [[http://www.youtube.com/watch?v=Ln29hZ9hhZ0 Summer's Sid and Nancy comparison gets flipped on its head.]]