* A la a MoodWhiplash, when asked about whether she wanted to own/ride an unconventional animal, Charlize talks about how mistreated and/or endangered animals always makes her sad and frustrated with society, which makes Creator/EmilyBlunt (who previously replied that she wanted to ride a tiger) feel guilty.
* After winning her Oscar, she described Creator/ReneeZellweger as:
-->''"She's like a pizza: always good..."''
* She revealed in an Creator/EllenDeGeneres interview that she used to practise making out with herself, and then asks Ellen whether she'd ever attempted to suck her inner elbow, pretending it was [[DoesThisRemindYouOfAnything lips]], before stopping herself awkwardly. The audience howl with laughter.
* In another interview, she talked about her enjoyment of ''Series/TheBachelor'' and how she felt about ''Bachelor in Paradise''.
--->'''Charlize:''' ''(after mentioning how {{squick}}y she found having sand as a bedroom floor)'' They're [the contestants] just sandy, dirty, hormonal things.
--->'''Ellen:''' ''[bemused]'' ...''That's'' your issue with the show?
--->'''Charlize:''' Yes! The sleeping around, [[SkewedPriorities I have no problem with]]. Thumbs up!
** While playing "Heads Up!":
--->'''Ellen:''' Sexiest man alive.
--->'''Charlize:''' ''[holding a photo of Creator/GeorgeClooney above her head]'' Music/JenniferLopez?!
* When she first met UsefulNotes/BarackObama, she had a spot of what she calls "verbal diarrhoea" (that she gets whenever she's nervous) and offered to take him to a strip club. She struggled to sleep for a month because the blunder haunted her whenever she closed her eyes.
* The cast of ''Film/TheItalianJob2003'' had to take special driving lessons to withstand the stunt driving. Charlize explained her annoyance that she had been booked for more lessons than the rest of the cast, but by day seven, when everyone had to swerve around several times, she could take the motion whereas her male co-stars had to excuse themselves (Creator/MarkWahlberg called her, wheezing queasily, and then she saw his silhouette vomiting behind his car).
* At the end of an [=ExtraTV=] interview promoting ''Prometheus'', the interviewer (A. J. Calloway) hesitates about asking another question and mumbles to himself that he won't ask it. Cue Charlize and Creator/GuyPearce lightly teasing him:
-->'''Guy:''' ''[goading]'' Go on. Go there.
-->'''Charlize:''' Wow, you actually stopped ''yourself''? That's never happened before. ''[to Guy]'' I've known this man for a long time and he's never short for words. That was unbelievable -- what was that? ''[to interviewer]'' Are you BLUSHING?!
-->'''A. J.:''' ''[sheepishly]'' Mildly.
-->'''Charlize:''' Oh my God!
-->'''A. J.:''' ''[giggling shyly]'' Charlize, stop!
-->''(everyone laughs)''
* During the filming of ''Film/TheHuntsmanWintersWar'' her eldest got a PrecociousCrush on Creator/EmilyBlunt, to the degree where they were driving past a poster for the film with Theron and Blunt on it and she (the daughter) blurted, "Look, it's ''Emily''!"
** The blooper where Theron ruined a take by suddenly belching in Emily's face. Blunt later said that the scene couldn't be filmed for the rest of the day because she couldn't stop laughing.
* The intense and uncomfortable mood and plot of ''North Country'' led to the cast mutually "sexually harassing" each other (e.g. FlirtatiousSmackOnTheAss) to ease the tension. The men had to harass the women in the movie, and then the women did it back off-camera.
** The ''Conan'' interview that discussed this led to Charlize admitting that she has a habit of having {{Precocious Crush}}es on older men, specifically Music/OzzyOsbourne. Creator/{{Conan|OBrien}} couldn't hide his shock.
* Charlize is always injuring herself on sets, but not in conventional or flattering ways. To name a few:
** Nearly losing her voice from doing her Megyn Kelly impression too much;
** Almost giving herself a concussion when she was tying her shoe and her head jerked back and collided with a bench;
** Locking her neck and landing her in the hospital for five days from laughing at ''Film/{{Borat}}'' too hard;
** She broke some teeth on ''Atomic Blonde''... because she was clenching them too much;
** Damaging her vocal chords from her labor scene in ''The Road'' because she wanted to prove SugarWiki/SheReallyCanAct when the director wanted to overdub her with ScreamingBirth mothers;
** Injuring her back on ''Tully'' from her weight gain.
* Trying to promote ''Film/AMillionWaysToDieInTheWest'' on ''Series/TheGrahamNortonShow''. Emphasis on ''try''.
--> "It's really funny and...[[SexSells I'm naked!]]"
** She also demonstrates the uncanny ability to imitate a goat.
*** To prelude that, Graham insinuates that she was very "comfortable" around sheep.
--->'''Graham:''' I imagine you were very comfortable around the sheep.
--->'''Charlize:''' What is ''that'' supposed to mean?
--->'''Graham:''' Weren't you raised around goats?
--->'''Charlize:''' Well start with ''that''. They [the audience] don't know that.
* When talking to Creator/MichaelBJordan for ''Variety''[='=]s ''Actors on Actors'' series of interviews, she got quite emotional talking about what it was like for her, as a white South African woman with two adopted African-American daughters, to watch ''Film/BlackPanther2018'', and to feel like it had broken so many glass ceilings in the way that it presented African and African-American characters, and how growing up under apartheid had left her with lingering issues of anger and guilt that she hadn't begun to resolve until her 30s, and how she couldn't wait until her daughters were old enough to watch it with her. Then:
-->'''Charlize:''' ''[wiping her eyes]'' [[SandInMyEyes Asshole]]. Now I need a tissue.
* Using a NotThatTheresAnythingWrongWithThat when talking about how proud she was of the lesbian sex scene in ''Atomic Blonde'' by pointing out:
-->''"...and I love me a love-making scene with a man ... I love it in my real life..."''
* In a Q&A for the Screen Actors Guild, she spoke about how hard it was to make decisions after winning several awards for ''Monster'' because she hadn't been used to having many options in Hollywood, to which she backtracks and feels frustratingly guilty for her FirstWorldProblems. Despite the host trying to defend her, Charlize [[GetAHoldOfYourselfMan "reminds" herself]]:
-->'''Charlize:''' No, working in a mine is hard. [[DeadpanSnarker Have some perspective, white lady.]]
* Her appearance on ''WebVideo/HotOnes'' has a variety of gems.
** The RunningGag hatred of the Da Bomb sauce, which included her [[FlippingTheBird flipping the bottle off]] because it ruined her experience, and then exaggeratingly pretending to throw it.
** This:
--->'''Charlize:''' Am I crying?
--->'''Sean:''' You have a glow...
--->'''Charlize:''' I have a "glow"...?
--->'''Sean:''' But I wouldn't call it--
--->'''Charlize:''' Which just means I'm really fucking sweating.
** As a whole, Sean pointing out her high tolerance. The comments section frequently notes this as well, comparing her to other guests that unexpectedly reacted badly to the hotter sauces: some of Hollywood's toughest men had ManlyTears whereas Charlize became a ClusterFBomb, {{deadpan snark|er}}ing cynic by the chicken wing.
* On Creator/ChelseaHandler's talk show, she was promoting ''Atomic Blonde'', which led to Chelsea pointing out her new ActionGirl status:
-->'''Chelsea:''' But, you like violence [in movies], right? You're rough!
-->'''Charlize:''' ''[confused]'' ...What does that--? How do you--?
-->'''Chelsea:''' [[InnocentInnuendo You like it rough?]]
-->'''Charlize:''' ...''[[[LampshadeHanging grins, and winks with a shrug]]]''
* [[https://twitter.com/CharlizeAfrica/status/1197702357015920640 Her turn]] at the "Instagram vs. Reality" meme.
* Just ''talking'' about ''WesternAnimation/InsideOut'' made her misty-eyed. She was embarrassed, but it convinced Emily Blunt to watch the movie at any chance she got.
* Her appearance on ''Podcast/HowDidThisGetMade'', stating that she had seen hardcore porn that was less horny than ''Film/HelloMaryLouPromNightII''
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