[[folder: Fridge Brilliance ]]

* If something radically altered your DNA, the first place the changes would show up would be at the site of a wound, where cells are dividing rapidly and new tissue is being produced. What's the first part of William Birkin to mutate dramatically? His right arm, which was riddled with bullets during the laboratory break-in. In addition, Birkin only changes forms after you fight him; he gets more alien every time he heals.
* It seems a bit odd that, when trying to start up the train in the B Scenarios, the game requires you to pick up two Joint Plugs and then immediately use them one room later, with nothing in between. Even more odd is that you only have to use one of the plugs on the generator - it automatically places the second one in with the first - when every other part of the game has you use items individually. Odd until you realize that what the game is doing is forcing you to have two inventory slots open, so that you can pick up the two-slot rocket launcher [[spoiler:Ada]] throws to you during the [[spoiler:Mr. X/Tyrant]] fight that starts immediately afterwards.
* As pointed out in a fan FAQ, the reason why HUNK's team attacked Birkin's lab in the first place was revenge for Wesker and Birkin stealing credit on the Nemesis project from the French branch of Umbrella by producing a viable sample in Lisa Trevor. With Wesker gone, Birkin was vulnerable and he had a shiny new virus that was ripe for the taking. This is proven by HUNK's CO being the R&D chief of the French branch, as well as certain details from the Wesker Report.
* If you take a closer look at the new Resident Evil 2 logo, you see lines on it. Then you realise it's actually some sort of road map of Raccoon City and the surrounding area.
* Doubles as fridge horror. But in the Remake, a man named Elliot calls out for a man named David when Leon spots him on the CCTV. Both the names Elliot and David are names of posthumous characters only named via files in the original game.
* While the game going to RE4's style of gameplay is a wise decision to keep the game up to date. It's also brilliance that the RE4 style and RE2 debuted with Leon. We've come full circle.


[[folder: Fridge Horror ]]

* Chief Irons has a pack of acid grenade rounds in his TortureCellar. At first glance, it may seem like they're there just for gameplay reasons. But think about what that room was used for, as well as the other chemicals such as chloroform and god knows what else. It's possible that Irons was secretly stealing acid rounds from the armory and using the sulfuric acid to torture people or break down their bodies ''Series/BreakingBad''-style to hide the evidence. How did he manage to get the acid out of the grenades without blowing himself up? In the remake of the first game, Barry refers to acid rounds as a "can of fizz" so maybe there's a way to easily open them up.
* Speaking of the Chief, what happened to the mayor's daughter's corpse? Obviously, he took it with him when he retreated to his torture cellar, but it's not there either when you enter it.
** The most logical answer is that he didn't feel like preventing her from turning into a zombie, and proceeded to wander from the torture chamber either into the police station or the sewer.
** It's implied that he murdered her himself, meaning she may not have ever been infected. The novelization goes with him hiding her corpse in a cabinet down there until he can get the time to, ''[[{{Squick}} eugh]]''... "Stuff & mount" her, which makes as much sense as any other explanation, awful as it is.
* William Birkin injected himself with the G-Virus, knowing full well that the virus could drive him to hunt down his own daughter and [[{{Squick}} inject her with mutated embryos.]] [[SarcasmMode Father of the year, people!]]
* Early in the remake, a frustrated Marvin tells Leon "If you see one of those things--uniform or not--you do not hesitate." The implication seems to be that he's speaking from experience: He got infected because he hesitated to shoot one of his now undead brothers in arms. It's also almost ''certainly'' foreshadowing to his impending zombification.
** Just before that, he qualifies his advice to Leon with "And don't make my mistake." It sounds like this was exactly what happened to the poor guy.