* ''WesternAnimation/ActionMan'': Alex (choleric), Rikki (melancholic), Grinder (phlegmatic), and Fidget (sanguine).
* In ''WesternAnimation/AdventuresOfTheGalaxyRangers'', The Series 5 Rangers: Zach (melancholic), Shane (choleric), Niko (phlegmatic), and Walter (sanguine). The series actually has very few episodes where all four are heavily involved, mostly breaking the team up into groups of two or three.
* ''Franchise/AlvinAndTheChipmunks'': [[HairTriggerTemper Dave]] (choleric), [[TheSmartGuy Simon]] (melancholic), [[AttentionWhore Alvin]] (sanguine), and [[ShrinkingViolet Theodore]] (phlegmatic).
* ''WesternAnimation/TheAmazingChanAndTheChanClan'', two examples.
** Four youngest children: Flip (choleric), Mimi (melancholic), Nancy (phlegmatic), and Scooter (sanguine).
** The middle four: Anne (choleric), Alan (sanguine), Tom (melancholic), and Suzie (phlegmatic).
* ''WesternAnimation/TheAmazingSpiez'': Lee (choleric), Marc (melancholic), Megan (phlegmatic), and Tony (sanguine). Megan and Marc sometimes switch roles.
* [[FanNickname Ozai's Angels]] ([[MyFriendsAndZoidberg and]] [[TheOneGuy Zuko]]) of ''WesternAnimation/AvatarTheLastAirbender'': [[TheChessmaster Azula]] (choleric), [[ByronicHero Zuko]] (melancholic), [[TheQuietOne Mai]] (phlegmatic), and [[{{Cloudcuckoolander}} Ty Lee]] (sanguine).
** The [[FanNickname Gaang]] themselves become one of these as well during the second season: Toph (choleric), Sokka (melancholic), Aang (sanguine), and Katara (phlegmatic).
** The Avatars before Aang also fit: Kyoshi (choleric), Yangchen (melancholic), Roku (phlegmatic), and Kuruk (sanguine).
** ''WesternAnimation/TheLegendOfKorra'' follows this perfectly: [[HotBlooded Korra]] (choleric), [[TallDarkAndHandsome Mako]] (melancholic), [[UptownGirl Asami]] (phlegmatic), [[TheCharmer Bolin]] (sanguine), and [[TheMentor Tenzin]] (eclectic).
*** Tenzin's Children (with the exception of Rohan): Jinora (melancholic), Ikki (sanguine), Meelo (choleric).
* ''WesternAnimation/AquaTeenHungerForce'': Master Shake (sanguine), Frylock (melancholic), Carl (choleric), and Meatwad (phlegmatic).
* ''WesternAnimation/TheBackyardigans'': Pretty hard to qualify. Technically, all of them are sanguine, but Pablo is probably the most. As for the others: Tasha (choleric), Uniqua (melancholic, though not depressive, since we're talking about a little kids' show), and Tyrone (phlegmatic). Austin starts out as phlegmatic, then moving on to melancholic; these days, he's starting to become more eclectic.
* ''[[WesternAnimation/BatmanTheAnimatedSeries The New Batman Adventures]]'': Though they rarely all worked together in the same episode, there was still a four-person "bat family." Robin (Tim Drake) is sanguine; Nightwing (Dick Grayson) is choleric; Batman is melancholic (as if it had to be said; he basically defines the temperament); and Batgirl is phlegmatic. Catwoman was the back-up choleric; in one episode, she and Nightwing even team up because of their similar personalities.
* And from ''WesternAnimation/BatmanBeyond'', we've got the Royal Flush Gang who also form a [[FiveManBand Five Man Band]] with the robotic Ace (eclectic), Authoritarian King (melancholic), conflicted Ten (choleric), Queen -- a proper lady who tries to keep the family united (phlegmatic), and fun-loving Jack (sanguine).
* ''WesternAnimation/BeastWars'': The four main Maximals: Optimus Primal (choleric), Rattrap (melancholic), Rhinox (phlegmatic), and Cheetor (sanguine).
* ''WesternAnimation/BeavisAndButthead'': Beavis (sanguine), Butt-Head (choleric), WesternAnimation/{{Daria}} (melancholic), and Stewart (phlegmatic).
* ''WesternAnimation/{{Bonkers}}'': Lucky Piquel (choleric), Fawn Deer (melancholic), Fallapart Rabbit (phlegmatic), and Bonkers (sanguine).
* ''WesternAnimation/TheBoondocks'': Robert (choleric), Huey (melancholic), Tom (phlegmatic), Riley (sanguine), and Jazmine (eclectic).
* ''WesternAnimation/{{Brickleberry}}'': Steve (melancholic), Denzel and Woody (choleric), Ethel (phlegmatic), Connie (sanguine), and Malloy (eclectic).
* ''WesternAnimation/CaptainPlanetAndThePlaneteers'': Kwame (melancholic - earth), Wheeler (choleric - fire), Linka (sanguine - wind / air), Gi (phlegmatic - water), and Ma-ti (eclectic - heart).
* ''WesternAnimation/CodeLyoko'': [[BirdsOfAFeather Yumi and Ulrich]] (melancholic), Jeremie (phlegmatic), Odd (sanguine), William (choleric) and Aelita (eclectic).
* ''WesternAnimation/CodenameKidsNextDoor'': Numbuh One - [[TheLeader Nigel Uno]] (melancholic), Numbuh Two - [[AcePilot Hoagie P. Gilligan Jr.]] (phlegmatic), Numbuh Three - [[GenkiGirl Kuki Sanban]] (sanguine), Numbuh Four - [[BloodKnight Wallabee Beetles]] (choleric), and Numbuh Five - [[SassyBlackWoman Abigail Lincoln]] (eclectic).
* ''WesternAnimation/TheDaltons'' has Joe (choleric), Jack (phlegmatic), William (melancholic), and Averell (sanguine).
* ''WesternAnimation/DannyPhantom'''s four-member "Team Phantom" can exhibit these:
** Choleric: Danny (though highly emotional), given his good leadership skills
** Melancholic: Sam (though not depressive), as a responsible [[DeadpanSnarker Stoic Goth]]
** Phlegmatic: Jazz, given her kind-but-perfectionist persona
** Sanguine: Tucker, as he's fun-loving.
* ''WesternAnimation/{{Daria}}'':
** The Fashion Club: Quinn (melancholic), Sandi (choleric), Stacy (sanguine), and Tiffany (phlegmatic).
** Daria's family: Quinn (sanguine), Helen (choleric), Daria (melancholic), and Jake (phlegmatic).
** As far as Lawndale High School: Mr. [=DeMartino=] (choleric), Mr. O'Neill (phlegmatic), Kevin and Brittany (sanguine), and Mack and Jodie (melancholic).
** Finally, there's [[FakeBand Mystik Spiral]]: Trent Lane (phlegmatic), Jesse Moreno (melancholic), Max Tyler (choleric), and Nicholas Campbell (sanguine).
* ''WesternAnimation/DastardlyAndMuttleyInTheirFlyingMachines'': Dick Dastardly (choleric), Klunk (melancholic), and Zilly (phlegmatic), and Muttley (sanguine).
* The family of ''WesternAnimation/DextersLaboratory'': Dexter (melancholic), Dee Dee (choleric), Mom (phlegmatic), and Dad (sanguine).
* The four main kids in ''WesternAnimation/{{Doug}}'': Doug (melancholic), Skeeter (sanguine), Patti (phlegmatic), and Beebe (choleric).
* ''WesternAnimation/FairlyOddParents'': Timmy (melancholic), Cosmo (sanguine), Wanda (phlegmatic), Poof (choleric), and Sparky (eclectic).
* ''WesternAnimation/FamilyGuy'':
** Neighbors: Peter (sanguine), Joe (melancholic), Cleveland (phlegmatic), and Quagmire (choleric).
** Family: Peter (sanguine), Lois and Stewie (melancholic), Meg and Brian (phlegmatic), and Chris (choleric).
* ''WesternAnimation/TheFlintstones'': Fred (choleric), Betty (melancholic), Wilma (phlegmatic), and Barney (sanguine).
* ''WesternAnimation/{{Futurama}}'': Fry (phlegmatic), Leela (choleric), Bender (sanguine), and Farnsworth (melancholic).
** Other characters: Zoidberg (sanguine), Hermes (phlegmatic), Nibbler (melancholic), Amy (choleric), and Scruffy (eclectic).
* ''WesternAnimation/GoofTroop'': Max (sanguine), Pete (choleric), P.J. (melancholic), and Goofy (phlegmatic).
* ''WesternAnimation/GravityFalls'': Grunkle Stan (choleric), Mabel (sanguine), Dipper (melancholic), Soos (phlegmatic), and Wendy (eclectic).
* ''WesternAnimation/GreenLanternTheAnimatedSeries'': [[CowboyCop Hal Jordan]] (sanguine), [[DrillSergeantNasty Kilowog]] (choleric), [[SpaceshipGirl Aya]] (phlegmatic) and [[TheAtoner Razer]] (melancholic).
* ''WesternAnimation/TheGrimAdventuresOfBillyAndMandy'': [[{{TheDitz}} Billy]] (sanguine), [[{{EnfantTerrible}} Mandy]] (choleric), [[{{TheGrimReaper}} Grim]] (melancholic), and [[{{NonActionGuy}} Irwin]] (phlegmatic).
* The four original ''WesternAnimation/HappyTreeFriends'': Cuddles (sanguine), Giggles (choleric), Toothy (melancholic), and Lumpy (phlegmatic).
* The four main kids on ''WesternAnimation/HeyArnold'': Arnold (melancholic), Helga (choleric), Gerald (sanguine), and Phoebe (phlegmatic).
* ''WesternAnimation/InvaderZim'': Zim (choleric), Dib (melancholic), Gaz (phlegmatic), and Gir (sanguine).
* ''WesternAnimation/JackieChanAdventures'':
** The Dark Hand Enforcers ([[HeelFaceTurn after Tohru left]]): Hak Foo (choleric), Chow (melancholic), Ratso (phlegmatic), and Finn (sanguine).
** The heroes once Tohru joined them: Uncle (choleric), Jackie (melancholic), Tohru (phlegmatic), and Jade (sanguine).
* ''WesternAnimation/JellyJamm'': Bello (choleric), Goomo (phlegmatic), Mina (melancholic), Rita (sanguine), and Ongo (eclectic).
* ''WesternAnimation/TheJetsons'': George (sanguine), Jane (melancholic), Elroy (phlegmatic), and Judy (choleric) and Rosie (eclectic).
* WesternAnimation/JonnyQuest: Jonny (melancholic), Hadji (sanguine), Dr Quest (phlegmatic), Race (choleric), and Bandit (eclectic).
* The seven founding members of the ''WesternAnimation/JusticeLeague'' seem to fit this pretty well for the most part: Superman (melancholic), Wonder Woman and Hawkgirl (choleric), Batman and Green Lantern (phlegmatic), Flash (sanguine), and Martian Manhunter (eclectic).
* ''WesternAnimation/{{Kaijudo}}: Rise of the Duel Masters'' has three groups:
** The Duel Masters: Nigel (choleric), Nadia (melancholic), Chavez (phlegmatic), Kimora (sanguine), and Jaha (eclectic).
** The Choten's side: Alakshmi (choleric), Suguru/[[spoiler: Ken Okamoto]] (melancholic), The Choten (phlegmatic), Fingers (sanguine), and Heller (eclectic).
* The four members of "Team Possible" in ''WesternAnimation/KimPossible'': Kim (melancholic), Ron (choleric), Rufus (sanguine), and Wade (phlegmatic).
* ''WesternAnimation/KingOfTheHill'': Hank Hill (melancholic), Dale Gribble (sanguine), Boomhauer (phlegmatic), and Bill Dauterive (choleric).
** The Hill family also qualifies: Hank (melancholic), Peggy (choleric), Bobby (phlegmatic), and Luanne (sanguine).
* ''WesternAnimation/TheLandBeforeTime'' series: Littlefoot (melancholic), Cera (choleric), Petrie (sanguine), Ducky (phlegmatic), and Spike (eclectic).
* ''WesternAnimation/LittlestPetShop2012'': Zoe and Pepper (choleric), Russell and Sunil (melancholic), Penny and Blythe (phlegmatic), Minka and Vinnie (sanguine).
* The kids in Ms. Frizzle's class on ''Literature/TheMagicSchoolBus'':
** The boys: Ralphie (sanguine), Carlos (choleric), Tim (melancholic), and Arnold (phlegmatic).
** The girls: Wanda (sanguine), Keesha (choleric), Dorothy Ann (melancholic), and Phoebe (phlegmatic).
* ''WesternAnimation/MenInBlack'': Jay (sanguine), Kay (melancholic), Elle (phlegmatic), and Zed (choleric).
* ''WesternAnimation/{{Metalocalypse}}'': Dethklok: Nathan (melancholic), Pickles (choleric), Skwisgaar (phlegmatic), Murderface (sanguine), and Toki (eclectic).
* ''WesternAnimation/{{Moonbeam City}}'': Dazzle is Melancholic, Pizzaz is Choleric, Chrysalis is Phlegmatic and Rad is Sanguine.
* ''WesternAnimation/MrBogus'': In one of the rare cases that Bogus and his cousin Brattus get paired up with their enemies, Ratty and Mole, it goes like this: Bogus (melancholic), Brattus (sanguine) Ratty (choleric), and Mole (phlegmatic).
* ''WesternAnimation/OscarsOasis'': On the rare ocassions Oscar teams up with the trio: Popy (choleric), Buck (melancholic), Oscar (phlegmatic), and Harchi (sanguine).
* ''WesternAnimation/ThePenguinsOfMadagascar'': Skipper (melancholic), Kowalski (phlegmatic), Private (sanguine), and Rico (choleric).
* ''WesternAnimation/ThePerilsOfPenelopePitstop'': Penelope is melancholic; Clyde is choleric; Dum-Dum and Pockets are phlegmatic; and the Hooded Claw (Sylvester Sneekly) is sanguine. Of the other characters: Softy (melancholic), Yak-Yak (sanguine), Snoozy (phlegmatic), and Zippy (eclectic).
* ''WesternAnimation/{{Phineas and Ferb}}''
** Fletcher family: [[{{Adorkable}} Lawrence Fletcher]] (melancholic), [[StraightMan Linda Flynn-Fletcher]] (sanguine), [[FieryRedhead Candace Flynn-Fletcher]] (choleric), [[TheAce Phineas Flynn-Fletcher]] (sanguine) and [[TheQuietOne Ferb Fletcher]] (phlegmatic)
** The Johnson family: Jack Johnson (sanguine), "Hawkeye" Johnson (melancholic), Jeremy Johnson (phlegmatic), Suzy Johnson (choleric).
** The kids: Baljett Tjinder (melancholic), Buford van Stomm (choleric), Isabella Garcia Shapiro (phlegmatic), and Irving Du Bois (eclectic).
** The teens: Stacy Hirano (sanguine), Jenny Brown and Vanessa Doofenshmirtz (melancholic), Coltrane and Monty Monogram (phlegmatic), and Albert Du Bois (choleric).
** OWCA: Major Francis Monogram (choleric), Carl Karl and Perry the Platypus (eclectic).
* ''WesternAnimation/PigGoatBananaCricket'': Pig (phlegmatic), Goat (choleric), Banana (sanguine), and Cricket (melancholic).
* ''WesternAnimation/ThePowerpuffGirls'': Bubbles (sanguine), Buttercup (choleric), Blossom (melancholic), Professor Utonium (phlegmatic).
* ''WesternAnimation/RegularShow'' generally has two characters per temperament for the main park staff:
** Sanguine: [[ManChild Rigby]] (also choleric) and [[{{Cloudcuckoolander}} Pops]] (also phlegmatic)
** Choleric: [[HairTriggerTemper Benson]] (also melancholic) and [[ThePrankster Muscle Man]] (also sanguine)
** Phlegmatic: [[MrFixit Skips]] --[[spoiler:formerly [[ByronicHero Walks]]]]-- (also melancholic) and [[TheQuietOne Hi-Five Ghost]] (also eclectic)
** Melancholic: [[CoolLoser Mordecai]] (also phlegmatic)
** Eclectic: [[NaiveNewcomer Thomas]]
* The human characters of ''WesternAnimation/ScoobyDooMysteryIncorporated'' appropriately [[ColourCodedForYourConvenience match their own color schemes]].
** Choleric + sanguine: Daphne (Red Hair), the most enthusiastic, emotional and outspoken of the group.
** Melancholic + choleric: Velma (Yellow Sweater), exhibiting brains when solving the mystery, also getting rather pushy, and tends to brood when things don't go her way.
** Phlegmatic + melancholic: Fred (Blue Trousers) -- although he is the leader of the team, he is obsessive (when it comes to traps) and emotionally high strung (when Daphne is in danger).
** Sanguine + phlegmatic: Shaggy (Green Shirt), the NonActionGuy who runs from anything spooky, is only there to react to the situations and makes jokes.
** Scooby (Brown Fur) fits into eclectic, as he is rather non-confrontational and the heart of the team.
** The main villains, as well: Mayor Jones (choleric), Professor Pericles (phlegmatic), Mr. E (melancholic), and Brad & Judy (sanguine).
* ''WesternAnimation/TheSimpsons'' have varied personalities over the years, but here is the most traditional lineup:
** The regulars at Moe's Tavern: Homer (choleric), Barney (sanguine), Carl (melancholic), Lenny (phlegmatic), and Moe (eclectic).
** The Bullies: Nelson (melancholic), Jimbo (choleric), Dolph (phlegmatic), and Kearney (sanguine).
** The Springfield Elementary Staff: Principal Skinner (melancholic), Edna Krabappel (sanguine), Groundskeeper Willie (choleric), Miss "Elizabeth" Hoover (phlegmatic), Lunch-lady Doris (eclectic).
* ''WesternAnimation/SonicBoom'': Sonic (phlegmatic), Tails (sanguine), Knuckles (choleric), Amy (eclectic), Sticks (melancholic).
*
''WesternAnimation/StevenUniverse'': Steven (sanguine), Garnet (phlegmatic), Amethyst (choleric), and Pearl (melancholic).
* ''WesternAnimation/StormHawks'': Aerrow (choleric), Stork (melancholic), Junko (phlegmatic), Finn (sanguine), and Piper (eclectic).
** The Cyclonians, as well: Ravess (choleric), Master Cyclonis (melancholic), Dark Ace (phlegmatic), and Snipe (sanguine).
* ''WesternAnimation/TaleSpin'': Rebecca (choleric), Kit (melancholic), Wildcat (phlegmatic), Baloo (sanguine), and Molly (eclectic).
* ''WesternAnimation/TeenTitans'' and ''WesternAnimation/TeenTitansGo'': Robin (phlegmatic), Beast Boy (choleric), Cyborg (sanguine), Raven (melancholic), and Starfire (choleric).
** And as in the comics, the Doom Patrol with Mento replacing Niles Caulder as the choleric leader.
* The tender engines in ''ThomasTheTankEngine'': Gordon (choleric), Henry (melancholic), Edward (phlegmatic), and James (sanguine).
** The narrow-gauge engines: Duke and Rheneas (melancholic), Sir Handel and Duncan (choleric), Peter Sam (sanguine), Rusty (phlegmatic) and Skarloey (eclectic).
* ''WesternAnimation/ThunderCats2011'':
** For the villains: Slithe (choleric), Vultaire (melancholic), Addicus (phlegmatic), Kaynar (sanguine), and Mumm-Ra (eclectic).
** In the [[ThunderCats original series]], Tygra was the melancholic one while Panthro was choleric. Kit and Kat's temperaments were also reversed.
* ''WesternAnimation/TinyToonAdventures'': Babs (choleric), Buster (melancholic), Plucky (sanguine), and Hampton (phlegmatic).
* ''WesternAnimation/TitanMaximum'': Palmer (choleric), Sasha (sanguine), Jodi (phlegmatic), Willie (melancholic), and Leon (eclectic).
** Originally, Palmer (choleric), Sasha (sanguine), Jodi (phlegmatic), Gibbs (melancholic), and Spud (eclectic).
* ''Franchise/{{Transformers}}'' has the Dinobots. [[TheLeader Grimlock]] would be choleric when compared to almost any other Autobot, but amongst his own team he's relegated to leukine, with violent, sociopathic [[TheLancer Slag]] as the resident choleric. The other three are fairly cut-and-dried, with pessimist Snarl as the melancholic, quiet and somewhat dim Sludge as the phlegmatic, and affable Swoop as the sanguine.
* The five main Autobots of ''WesternAnimation/TransformersAnimated'': Optimus Prime (choleric), Ratchet (melancholic), Prowl (phlegmatic), Bumblebee (sanguine), and Bulkhead (eclectic).
* ''WesternAnimation/TransformersPrime'':
** Team Prime: Arcee and Ultra Magnus (choleric), Ratchet (melancholic), Bumblebee (phlegmatic), Bulkhead, Wheeljack and Smokescreen (sanguine), and Optimus (eclectic).
** The Decepticons: Megatron and Starscream (choleric), Dreadwing and Predaking (melancholic), Soundwave (phlegmatic), Knock Out (sanguine), Breakdown and Shockwave (eclectic).
* ''WesternAnimation/TransformersRescueBots'':
** The Rescue Bots are: Heatwave (melancholic), Chase (choleric), Boulder (sanguine), and Blades (phlegmatic).
* WesternAnimation/UltimateSpiderMan: Power Man (melancholic), Iron Fist (phlegmatic), White Tiger (choleric), Nova (sanguine), and Spider-Man (eclectic).
* UncleGrandpa: Uncle Grandpa (melancholic), Giant Realistic Flying Tiger (choleric), Mr. Gus (phlegmatic), Pizza Steve (sanguine), and Belly Bag (eclectic).
* ''WesternAnimation/TheVentureBrothers'': Brock Samson (choleric, sometimes melancholic), Dean (phlegmatic), Dr. Venture (melancholic, sometimes choleric), and Hank (sanguine).
* The latter half of ''WesternAnimation/WheelieAndTheChopperBunch''; Chopper (choleric), Revs (melancholic), Hi-Riser (phlegmatic), and Scrambles (sanguine).
* The main group from ''WesternAnimation/{{WITCH}}'' fits: Will (phlegmatic), Irma, (sanguine), Taranee (melancholic), Cornelia (choleric), and Hay Lin (eclectic).
** Some of the guys on the show show fit too: Caleb (choleric), Matt (phlegmatic), and Blunk (sanguine).
* ''Franchise/WinnieThePooh'': Pooh (phlegmatic), Tigger (sanguine), Rabbit (choleric), Eeyore (melancholic, [[TheEeyore of course]]), and Piglet (eclectic).
* ''WesternAnimation/XiaolinShowdown'': Raimundo (sanguine-wind), Omi (phlegmatic-water), Clay (melancholic-earth), Kimiko (choleric-fire).
* ''WesternAnimation/YoungJustice'': Kid Flash (sanguine), Speedy (choleric), Robin (melancholic), and Aqualad (phlegmatic). After Speedy leaves, Superboy fills in for the choleric.
----