* ''GodHand'' has the Four Devas, as follows:
** The BigBad - Belze
** TheDragon - Azel (also the EvilCounterpart to Gene)
** The EvilGenius - The mercenary Dr. Ion.
** TheBrute - Elvis
** The DarkChick - Shannon (TheVamp)

* ''VideoGame/GodOfWar'' the Gods in the third game form one:
** BigBad - Zeus (King of Olympus)
** TheDragon - Poseidon (god of the sea)
** The EvilGenius - Hermes (god of merchants, thieves and other things like that)
** TheBrute - Hades (god of the underworld)
** The DarkChick - Hera
** SixthRanger - Helios (god of the sun)
** SixthRangerTraitor - Hercules (not actually a god)

* ''VideoGame/GoldenSun: The Broken Seal'' & ''Golden Sun: The Lost Age'': The party below:
** The BigBad - Saturos, the leader of the Apollo Sanctum raiding party and the BlueOni to Menardi's Red. Karst is the BigBad and also TheDarkChick in the sequel, wanting to avenge her sister's death.
** TheDragon - Menardi, Saturos' NumberTwo and the RedOni to his Blue. Agatio in the sequel, who is also TheBrute.
** EvilGenius - Alex, the level-headed mediator and negotiator [[spoiler: who is also a HiddenAgendaVillain.]]
** SixthRanger - Felix, a crucial member whose loyalty is somewhat in question.
*** Worth noting that although this setup is active from the start, neither Agatio or Karst appear in ''The Broken Seal''. With Felix's loyalty in question [[spoiler: since he'd finished his main purpose (opening Venus Lighthouse), and with Saturos and Menardi dead]], ''The Lost Age'' sees the group dynamic change, especially when [[spoiler: Alex reveals himself as a HiddenAgendaVillain by the end, and potentially the whole series' BigBad]].

* ''VideoGame/{{Gradius}}'' series:
** The BigBad: Bacterion
** TheDragon: Gofer
** TheEvilGenius: Venom
** TheBrute: Zelos
** TheDarkChick: Mother Computer

* ''VideoGame/GrandTheftAutoIV'': Faustin Family
** BigBad: Mikhail Faustin
** TheDragon: Dimitri Rascalov
** EvilGenius: Vlad Glebov
** TheBrute: Ivan Bytchkov
** DarkChick: Joseph Kaplan

* The Lost in ''[[GrandTheftAutoIVTheLostAndDamned The Lost And Damned]]''
** BigBad: Billy Grey
** TheDragon: Johnny Klebitz
** EvilGenius: Brian Jeremy
** TheBrute: Jim Fitzgerald
** DarkChick: Terry Thorpe

* ''VideoGame/GrandTheftAutoSanAndreas'': CRASH and the Loco Syndicate
** BigBad: Frank Tenpenny
** TheDragon: Eddie Pulaski
** EvilGenius: Jizzy B. and Mike Toreno
** TheBrute: T-Bone Mendez
** TheDarkChick: [[spoiler: Big Smoke and Ryder.]]
** SixthRangerTraitor: [[spoiler:Jimmy Hernandez]]

* ''{{VideoGame/Gun}}''
** BigBad: Colonel Thomas Magruder
** TheDragon: Reverend Josiah Reed
** The EvilGenius: Mayor Hoodoo Brown
** [[TheBrute The Brutes]]: Sergeant Hollister and Dutchie
** [[TheDarkChick The Dark Chicks]]: J.J. Webb and Dave Rudabaugh
** SixthRangerTraitor: Jenny

* ''GunstarHeroes''
** The BigBad - General Gray
** TheDragon - Smash
** The EvilGenius - Black
** TheBrute - Orange
** The DarkChick - Pink
** The SixthRangerTraitor - Green

* ''{{Halo 2}}'': The Covenant hierarchy
** The BigBad - Prophet of Truth
** TheDragon - Tartarus
** The EvilGenius - Prophet of Mercy
** TheBrute - Prophet of Regret
** The SixthRangerTraitor- The Arbiter Thel 'Vadamee, the Spec Ops Commander Rtas 'Vadumee

* ''HeavyRain''
** BigBad: The Origami Killer aka [[spoiler:Scott Shelby]]
** TheDragon: Paco Mendes
** EvilGenius: Dr. Adrian Baker
** TheBrute: Mad Jack
** DarkChick: [[spoiler:Lauren Winter [[UnwittingPawn unwittingly]]]]

* ''VideoGame/{{Hitman}} Absolution'': Dexter Industries
** The BigBad: [[CorruptHick Blake Dexter]]
** TheDragon: Layla Stockton
** TheEvilGenius: [[MadScientist Dr Ashford]] (and by extension, Dr Green and Dr Valentine as well)
** TheBrute: Sanchez
** The DarkChick: Lenny "The Limp" Dexter
** The SixthRanger: [[PsychoForHire Edward Wade]]

* House of the Dead 2
** BigBadDuumvirate: The Emperor & Caleb Goldman
** TheDragon: The Magician
** TheEvilGenius / TheDarkChick: Caleb Goldman
** TheBrute(s) Judgement, The Hierophant, & Strength
** TeamPet: The Tower

* ''VideoGame/HyperdimensionNeptuniaV'': The Seven Sages
** BigBad: Rei Ryghts
** TheDragon: Anonydeath
** The Starscream: Arfoire
** TheBrute: Copypaste
** EvilGenius: Mr. Badd
** DarkChick: Abnes
** TeamPet: Pirachu
** SixthRanger: [[spoiler: Peashy/Yellow Heart]]

* ''VideoGame/TheInfynPrism'':
** BigBad: Rasen
** TheDragon: Po
** EvilGenius: Wyndi
** TheBrute: Golem
** DarkChick: Atlese
** [[SixthRanger Sixth Rangers]]: Kaga and Akarui.

* ''[[DarkForcesSaga Jedi Knight: Dark Forces II]]'': The Seven Dark Jedi:
** BigBad: Jerec
** TheDragon: Sariss
** EvilGenius: Boc and Pic
** DarkChick / SixthRangerTraitor: Yun
** {{The Brute}}s: Maw and Gorc

* ''[[DarkForcesSaga Jedi Outcast]]''
** BigBad - Desann
** TheDragon [=/=] DarkChick - Tavion
** EvilGenius - Galak Fyyar
** TheBrute - Reelo

* ''[[DarkForcesSaga Jedi Academy]]''
** BigBad [=/=] EvilGenius - Tavion
** TheDragon - Alora
** TheBrute - Kothos Twins
** The DarkChick / [[spoiler: SixthRangerTraitor]] - Rosh

* ''Videogame/KidIcarusUprising'': The Underworld Army:
** BigBad: Medusa
** TheDragon: Thanatos
** EvilGenius: Pandora
** TheBrute: Hewdraw
** DarkChick: Dark Lord Gaol
** TeamPet: Twinbellows
** SixthRangerTraitor: Dark Pit
** [[spoiler: TheManBehindTheMan: Hades]]

** The Forces of Nature:
*** BigBad: Viridi
*** TheDragon: Phosphora
*** EvilGenius: Arlon
*** TheBrute: Cragalanche

* ''TheKingOfFighters'': The NESTS Cartel
** The BigBad - Igniz, also TheStarscream himself to his own father
** TheDragon - Original Zero, doubles as a DarkChick
** The EvilGenius / TheStarscream - Cloned Zero
** TheBrute - Krizalid, K9999 / Nameless, Angel
** The {{Dark Chick}}s / {{Sixth Ranger Traitor}}s - Diana, Foxy, Kula Diamond

* ''VideoGame/KingdomHearts'' (the Disney bosses)
** The BigBad - Maleficent
** TheDragon - Captain Hook; later [[spoiler:Riku]]
** The EvilGenius - Jafar
** TheBrute - Oogie Boogie
** The DarkChick - Ursula
** The SixthRangerTraitor - Hades. He actually talks back to Maleficent, telling her to piss off, and goes on to abandon her plan and continue doing his own thing in Olympus.
** The SixthRanger - Riku
** TheManBehindTheMan - [[spoiler:Xehanort's Heartless]]

* ''VideoGame/KingdomHeartsChainOfMemories''
** The BigBad - Marluxia, who incidentally is also TheStarscream for the BigBad of ''Kingdom Heart II's'' FiveBadBand.
** TheDragon / The DarkChick - Larxene, the [[TheSmurfettePrinciple only]] [[TheChick female]] member.
** The EvilGenius - Vexen, the classic MadScientist.
** TheBrute - Lexaeus; though he's every bit the intellectual Zexion and Vexen are.
** The [[TheHeart Dark Heart]] - Zexion, the non-fighter.
** The SixthRangerTraitor - Axel, who [[ChronicBackstabbingDisorder backstabs EVERYONE.]]

* ''VideoGame/KingdomHeartsII'' All that remains of Organization XIII
** The BigBad - Xemnas
** TheDragon[=/=]CoDragons - Saix and/or Xigbar
** The EvilGenius - Luxord
** TheBrute - Xaldin
** The DarkChick - Demyx
** The SixthRangerTraitor - Axel, who ditches the Organization XIII for his own agenda, and later on [[spoiler: allies with the protagonists]]

* ''VideoGame/KingdomHeartsBirthBySleep'' Master Xehanort's crew
** The BigBad[=/=]The EvilGenius - Master Xehanort
** TheDragon - Vanitas
** TheBrute - Braig
** TheDarkChick - Maleficent
** TheSixthRanger - Pete. Unlike the others, he isn't recruited by Master Xehanort personally, but by Maleficent, which makes him, through her, an indirect ally to Xehanort.

* ''VideoGame/KingdomHearts3DDreamDropDistance'' The new Organization XIII forms one out of the currently known members.
** The BigBad - Master Xehanort
** TheDragon - Young Xehanort
** TheEvilGenius - Xemnas
** TheBrute - Ansem, Seeker of Darkness
** TheDarkChick - Xigbar

* ''KingdomsOfAmalurReckoning'': The Tuatha Dheon
** The BigBad - Gadflow
** TheDragon - Witch Knight Malwyn
** TheBrute - The Cur
** The EvilGenius - Saturnyn, [[spoiler:aka Bisarane]]
** The DarkChick - Witch Knight Myrna

* ''Kingpin: Life Of Crime'' - The Mafia
** BigBad: The Kingpin
** TheDragon: Nikki Blanco
** EvilGenius: Moker
** TheBrute: Heilman
** DarkChick: Blunt

* ''VideoGame/KirbySqueakSquad''
** BigBad - Daroach
** TheDragon[=/=]DarkChick - Spinni
** EvilGenius - Doc
** TheBrute - Storo/Stron
** {{Giant Space Flea|FromNowhere}} [[SealedEvilInACan In A Can]] - [[spoiler:Dark Nebula]]

* ''KnightsOfTheOldRepublic''
** The BigBad - Darth Malak (formerly Darth Revan)
** TheDragon - Darth Bandon (formerly Darth Malak)
** The EvilGenius - Admiral Karath
** TheBrute - Calo Nord
** The DarkChick - [[spoiler: [[FaceHeelTurn Darkside Bastila]] ]]

* ''VideoGame/KnightsOfTheRound''
** BigBad - Garibaldi
** TheDragon - Arlon
** The EvilGenius - Phantom
** TheBrute - Balbars
** The DarkChick - Scorn
** SixthRanger - Muramasa
** SixthRangerTraitor - Brafford

* ''LANoire'': [[spoiler:Suburban Redevelopment Fund]]
** BigBad - [[spoiler:Leland Monroe]]
** TheDragon - [[spoiler:William Worrell]]
** EvilGenius - [[spoiler:Harlan Fontaine]]
** TheBrute - [[spoiler:Ira Hogeboom unwittingly]]
** DarkChick - [[spoiler:Curtis Benson]]
** SixthRanger - [[spoiler:Roy Earle]]

* ''VideoGame/TheLegendOfZeldaTwilightPrincess''
** BigBad - [[spoiler: Ganondorf]]
** TheDragon - [[spoiler: Zant]]
** TheBrute - King Bulbin
** TeamPet - Lord Bulbo
** The EvilGenius - Phantom Zant

* ''Videogame/TheLegendOfZeldaOcarinaOfTime''
** BigBad - Ganondorf
** TheDragon - Phantom Ganon and later Twinrova, who also doubles as the EvilGenius.
** DarkChick - [[spoiler: BrainwashedAndCrazy Nabooru]]
** TheBrute - Volvagia
** SixthRangerTraitor - Bongo Bongo

* ''VideoGame/TheLegendOfZeldaOracleGames''
** BigBad - [[ItWasHisSled Ga]][[HijackedByGanon non]]
** TheDragon - Twinrova
** TheEvilGenius - Veran, who plans to manipulate and control time to achieve her goal.
** TheBrute - Onox, whose plan amounts to kidnapping Din, destroying the Temple of Seasons, and letting the world unravel itself.
** TeamPet - Vire, minion to Veran or Onox who pursues Link across regions.
** SixthRanger - The Great Moblin. He's on the take from these guys, but isn't really a member of the group.

* ''Videogame/TheLegendOfZeldaTheWindWaker''
** BigBad - Ganondorf
** TheDragon - Helmaroc King and Phantom Ganon
** TheBrute - Molgera and Jalhalla
** DarkChick - Gohma
** SixthRangerTraitor - Cyclos

* ''TheLegendOfZeldaPhantomHourglass''
** BigBad - [[spoiler: Bellum]]
** TheDragon - Ghost Ship
** EvilGenius - Gleeok
** TheBrute - Eox
** DarkChick - [[spoiler: The Cubus Sisters]]
** SixthRangerTraitor - Jolene

* ''TheLegendOfZeldaSpiritTracks''
** BigBad - Malladus
** TheDragon - Chancellor Cole
** TheBrute - Cragma
** EvilGenius - Fraaz
** TeamPet - Evil Train
** SixthRangerTraitor - Byrne

* LegendOfZeldaCDIGames: "Ganon and his Minions"
** BigBad - Ganon
** TheDragon - Hectan
** EvilGenius - Goronu
** TheBrute - Militron
** TheDarkChick - Lupay

* ''[[VideoGame/LegoAdaptationGame Lego Batman]]'': The Riddler's group
** BigBad - The Riddler
** TheDragon - Two-Face
** EvilGenius - Mr. Freeze
** TheBrute - Clayface
** TheDarkChick - Poison Ivy

* Also from ''Lego Batman'': The Penguin's group
** BigBad, doubling as EvilGenius - The Penguin
** TheDragon - Catwoman
** [[TheBrute The Brutes]] - Killer Croc and Bane
** TheDarkChick - Man-Bat

* Also from ''Lego Batman'': The Joker's group
** BigBad - The Joker
** TheDragon - Harley Quinn
** EvilGenius - The Mad Hatter
** TheBrute - Scarecrow
** TheDarkChick - Killer Moth

* The group of villains from ''VideoGame/LunarEternalBlue'' qualifies.
** The BigBad - Zophar
** TheDragon - Ghaleon
** TheBrute - [[spoiler:Master Lunn]]
** The EvilGenius - Borgan. Not really genius compared to other examples of this character trope but the closest one that this game offers.
** The DarkChick - Mauri ([[spoiler: when she is under the influence of Zophar]]) and arguably [[spoiler: Fake Althena]]
** SixthRangerTraitor - Leo

* The group of villains from ''[[VideoGame/LunarTheSilverStar Lunar: Silver Star Story Complete]]'' qualifies as well.
** The BigBad - [[spoiler: Magic Emperor Ghaleon]]
** TheDragon - Xenobia
** The EvilGenius - Taben
** TheBrute - Royce (due to her being a Chaotic Evil ForTheEvulz BloodKnight)
** The DarkChick - [[spoiler: Dark Althena/ Luna]]
** SixthRangerTraitor - Phacia and [[spoiler: Nash]]