''Love and Other Drugs'' is a 2010 SexComedy movie about a Viagra salesman who falls in love with a young woman who suffers from Parkinson's Disease; they start a relationship based on sex but end up actually falling in love with each other, to their mutual chagrin. It may best be known for starring Creator/AnneHathaway, star of such GirlNextDoor roles as ''Film/ThePrincessDiaries'' movies, and for the amount of nudity and sex scenes in the film, to the point it can almost be considered PornWithPlot.

A minor subplot involves Jamie's fat, nerdy brother Josh who is kicked out of the house by his lover and moves in with Jake, disrupting his intimate life. HilarityEnsues.

!!This film provides examples of:

* BittersweetEnding: [[spoiler: Sure, Jake and Maggie end up together, but they're both very much aware that she will eventually lose all physical and mental coordination.]]
* {{Bowdlerise}}: The Spanish subtitles are hilarious because they have all the swear words censored... in a film with graphic sex scenes. It seems ''talking'' about sex is bad, but not ''showing it!''
* BrokenAesop: it's a little hard to take the message that "Love is more important than sex" seriously when ''most of your film'' is about people having sex or talking about having sex.
* CaliforniaDoubling: Averted, initially, as it is set in Pittsburgh and filmed there, but for their trip to Chicago, they just replaced the Art Institute of Pittsburgh banners on street lamps with Art Institute of Chicago ones and called it good. They even show Pittsburgh's Liberty Avenue while Maggie is walking across the street from Jamie's convention to the Parkinson's group.
* TheCharmer: Jamie even [[LampshadeHanging lampshades it]], delightfully enough.
-->'''Jamie''': You're gonna like me eventually. Everyone does.
* DefrostingIceQueen: Subverted. Jamie eventually does convince Maggie to be his girlfriend, but she doesn't change her behavior until the very end.
* DiagnosisFromDrBadass: Trey tells Jamie EXACTLY what type of pain he's delivering.
* DramaticIrony: Jamie works as a Drug Rep for Pfizer, the creator of Viagra, and he soon begins successfully selling the drug. Later on, he engages in a threesome at a party, taking Viagra to stimulate himself; [[spoiler: he ends up having a negative reaction to the drug, which leaves him with a painfully erect and extremely sore penis, forcing him to go to the hospital. Yes, it turns out that the sex obsessed Viagra salesmen can't take Viagra himself.]]
* {{Fanservice}}: [[MrFanservice Both]] [[MsFanservice leads]] spend about half the movie butt naked.
* FriendlyTickleTorture: Jamie attacks Maggie with tickles during a scene on the couch. Like pretty much everything else they do in the movie, it ends with them having sex.
* TheFilmOfTheBook: The original book was actually a non-fictional retelling of the history of Viagra.
* GirlOnGirlIsHot: And also shameless.
* GoodTimesMontage
* GoodPeopleHaveGoodSex: Despite how sex-obessessed the characters are, nothing kinkier than oral is even discussed.
* HotAndCold: Maggie is a classic case.
* IllGirl
* ImmodestOrgasm: Many.
* InterchangeableAsianCultures: One character makes a terrible, "sexy" pun about her friend's race as a lead-up to a threesome. "She's Thai, and I'm Thai-curious." Which is made worse by the fact that the girl is blatantly Filipino.
* LadyKillerInLove: This is what the movie is about, and what makes it sweet.
* TheLoinsSleepTonight: It's about a Viagra salesman.
* JerkWithAHeartOfGold: Jamie is this, though it takes a while for even him to realize it. Maggie can be something of a bitch, too.
* OscarBait
* PlayingAgainstType: Even for the director, Ed Zwick, the movie is a departure from his Oscar bait fare, but harks back to his very early work.
* PresentDayPast: There's the introduction of Viagra and Prozac, and there's the bit with 90s ghettoblasters at the start. Nothing else sets this is '96. One character justifies being addicted to internet porn by saying "Isn't everybody?" No, not in '96 they weren't. Not even in '97. Seriously, cast your mind back to how much porn there was on the internet when the first Grand Theft Auto came out. There's even a scene Josh compares Jamie's penis to the Eye of Sauron, back before there was a common consensus on what that actually looked like, it being 5 years before Film/TheLordOfTheRings was a movie. Not to mention in the beginning of the film, there's Flat-screen LCD TV's in the background.
* ProductPlacement: For Pfizer and their products (mostly Viagra), but its somewhat subverted in that the entire company comes off looking like a bunch of douchebags.
** And lots of Bud and Bud Light abound.
* RaceForYourLove
* SexMontage: Natch.
* AThreesomeIsHot: Said threesome.
* UglyGuyHotWife: Josh and whatsername.
* UnsympatheticComedyProtagonist: The men in this film are jerks. Gyllenhaal's redeemed by ThePowerOfLove.
* WhatHappenedToTheMouse: A homeless man keeps showing up to take the Prozac Jamie dumps in the trash and once makes an offhand comment that he has a job interview later before scampering off with the drugs. We had seen him take the drugs repeatedly, but the relevance of this fact is never addressed so the "job interview" comment is borderline BigLippedAlligatorMoment.
** It's a joke. He's been taking the Prozac and he got his life in order.