After the end of ''TheKidsInTheHall'', there was one last project that the troupe wanted to perform - their own movie.

Released in 1996, it tells the tale of Chris Cooper, a pharmacist who works with his love, Alice, trying to create the world's greatest antidepressant for his employer, Roritor Pharmaceuticals. It also details the lives of several people with massive issues (like death metal musician Grivo and repressed homosexual Wally Terzinsky) who eventually get put on this new antidepressant, [=GLeeMONEX=]. The drug is rolled out as Chris pushes it to keep from getting fired. And at first, everything is comically okay.

Until it's revealed just why you don't want to [[TerminallyDependentSociety rush an antidepressant out the door.]]

With mixed personal sentiments about the film, ''The Kids In The Hall'' went their separate ways until their reunion in 2000 and subsequent tours in 2007-08, and the 2010 ''DeathComesToTown'' miniseries.

----
!! This film contains examples of:

* AnAesop: "The key to being happy is to know you won't be happy ''every single day''. Tra-la la-la la-la."
* AppliedPhlebotinum
* BattleInTheCenterOfTheMind: With the fresh approach of a happiness-induced coma. A good point, too. After all, mental health is not predicated upon happiness alone. It's about having the right emotion when it's needed.
* BlackComedy: The entire plot is about folks using antidepressants until they're too blissed out to do anything. And one of the troupe's darkest bits of comedy, Cancer Boy, is brought back for the film (he's actually not on the drug; he already blithely accepts his imminent demise).
* BlackMetal: Obviously the kind of music that Grivo performs... until he takes [=GLeeMONEX=].
* BlatantLies: Roritor gives Marv a new project and then immediately asks for a status update. Befuddled, Marv states, "Oh, we're on top of that, Don!" Roritor looks at him dubiously for a moment before moving on.
* TheCameo: BrendanFraser as a drug tester (who knows he's getting the placebo) and Creator/JaneaneGarofalo.
* CallBack: Cisco tells a story about a bird hitting his windshield. Later, a bird hits him right in the eye, forcing him to wear an eyepatch for the rest of the film.
* Cloudcuckoolander: Don Roritor is an insane millionaire.
* CorruptCorporateExecutive: Don Roritor, who wants to speed the drug into production to pick up his failing pharmacological empire.
* DrivenToSuicide: Chris's father, when Chris was a kid. His father's depression was what inspired Chris to develop an effective antidepressant
* EstablishingCharacterMoment: Don Roritor is introduced helicoptering into his skyscraper while his minions hurriedly swap out the office carpets so that they will match his socks.
* {{Expy}}: The Kids created Wally Terzinsky to be an Expy of their sketch show's Danny Husk.
* FolkMusic: What Grivo ends up performing after starting [=GLeeMONEX=].
* FlamboyantGay: Wally once he's on [=GLeeMONEX=].
* {{Foreshadowing}}: Chris is probably at his apex when he comes out to present an award and the MTV Music Awards. The song they play to bring him out? "Spiralling Shape" by TheyMightBeGiants, a ditty about how folks' lives are ruined by some mysterious object that drives them insane and happy. Things start to fall apart shortly thereafter.
* FunnyForeigner: The cabbie who serves as the FramingDevice.
* GenderBender: In classic ''Kids In The Hall'' tradition, many of the roles are played by the five main cast members regardless of gender.
* GoneHorriblyRight: [=GLeeMONEX=] works by bringing someone's favorite memory to the forefront, enabling them to get past their depression. It eventually causes it to get stuck there... immobilizing folks as they remember their favorite memory in a loop.
* HappyPlace
* IDrankWhat: Don Roritor just loves the secret ingredient that Marv put into the coffee. Marv refuses to tell [[ToiletHumor what it is]].
* InspirationallyDisadvantaged: Cancer Boy, up for an MTV Music Award.
* LittlestCancerPatient: Parodied with Cancer Boy.
* LotusEaterMachine
* NoCelebritiesWereHarmed: Don Roritor is heavily based on Mark [=McKinney's=] imitation of producer Lorne Michaels. Also counts as BitingTheHandHumor.
* NoControlGroup: Averted and discussed [[PlayedForLaughs for laughs]], as Brendan Frasier's [[TheCameo cameo]] appearance figures out that he's part of the control.
* PunnyName: Grivo, the sad rocker, has a name that's a combination of rockstar Divo and "grieve"
* RealitySubtext: Kevin [=McDonald=], who plays Dr. Cooper, was going through a divorce and suffering from severe depression while filming. In an interview he stated that it was very hard for him to even get up and on the set in the mornings and at times the director would yell "cut" and he would walk off-set and start crying.
* ScrewTheRulesIHaveMoney: Don and his crew of subordinates, Chris during [=GLeeMONEX=]'s heyday.
* ScrewTheMoneyIHaveRules: Chris (eventually) and his fellow scientists.
* TailorMadePrison: Every Gleemonex-user's HappyPlace.
* TastesLikeDiabetes: [[invoked]] "Happiness Pie".
* TerminallyDependentSociety
* TestosteronePoisoning: Wally's happiest moments are of getting berated by his drill instructor and doing calisthenics. He also has what is apparently a fantasy involving a mission to have sex with enemy beefcakes.
-->'''Drill sergeant:''' ''(to Wally)'' You go over there and fuck them. I'll stay here and masturbate. Go, go, go!
* ToiletHumor: Marv's happiest thought - [[spoiler: getting a pal to urinate into Don's coffee]]. Don's happiest thought? [[spoiler: Drinking it.]]
* TransparentCloset: Wally Terzinsky, who is in denial despite the fact that his family all discusses it behind his back. As his therapist states:
-->"You... are gay. You -- you are gay, you are a ''homosexual''. The opposite of straight, you're gay. I know it, your family knows it. ''Dogs'' know it! Everyone seems to know it except you!"
* WimpFight: In the second act climax, the wimpy Dr. Cooper and the effete Don Roritor engage in an childish brawl. First, Cooper slaps Roritor's accusatory finger out of his face about twenty times in a row. Finally the pair awkwardly grapple and push each other for a few moments. When they finally break away, they're humorously flustered and gasping for breath, as if they'd been through a war. In a later scene, Roritor wears an outlandish full-arm splint for his injured finger.
* YourMindMakesItReal