[[caption-width-right:300:Readin', Writin', and Radiation!]]
->''"It rotted their bodies. It corrupted their minds. And that's the good news."''

Tromaville ([[Creator/{{Troma}} See what they did there?]]) High School is right next to a nuclear power plant. A ''leaky'' nuclear power plant. [[TemptingFate You can already tell this isn't exactly the best of situations, right?]] First of all, the school's honor students turn into ultra-violent mutated thugs. Then, the school is menaced by a spiky nuclear mutant. And good, clean cut, boy-next-door Warren and his equally squeaky clean girlfriend, Chrissy, are caught in the middle.

This 1986 sci-fi/horror/comedy film was followed by two sequels in TheNineties. Another follow up, titled ''Return to Nuke 'Em High'' and split into two parts, was announced to coincide with Troma's 40th anniversary; the first installment was released in 2013.

!!This movie contains examples of:
* AbortedArc: Warren's HulkingOut is never dealt with again once he goes on the rampage a grand total of once.
* TheAggressiveDrugDealer: When they say "Buy our weed", they fucking ''mean it''.
* BadWithTheBone: One of the gang members uses one as a weapon.
* BalloonBelly: Overlaps with a good amount of {{Squick}}.
* BadassBookworm: The Cretins were once the honor society before this mess.
* BMovie
* BodyHorror: Mutated weed ends up mutating people in horrific ways.
* ChekhovsGun: The [[FrickinLaserBeams laser]] in the school's lab is used in the first film's climax to kill a mutant and destroy the school.
* EyeScream
* FetusTerrible: The killer mutant is ''technically'' Chrissy's baby, although it came out the wrong end.
* HulkingOut: Happens to Warren at one point.
* ILoveNuclearPower: Causes every problem in the story.
* InNameOnly: The sequels have only slightly more to do with the original than ''Film/{{Troll 2}}'' has to do with the first ''Film/{{Troll}}''.
* LoadBearingBoss: Justified by the fact that the laser in story reacts violently with nuclear materials.
* MarijuanaIsLSD: Justified in that it grows right next to the local nuclear plant.
* MediumAwareness: Everyone in the second sequel knows it's the second sequel and constantly claim things like "I thought you were killed at the end of Class of Nuke'em High 2".
* NoOSHACompliance: And how. The [[BadBoss director of the nuclear plant]] dismisses any leaking of radioactive materials and seems more concerned with covering it up than solving the problem. When employees at the Tromaville Nuclear Utility start collapsing due to radiation poisoning, their colleagues don't even bat an eyelid with one of them even ''stepping right over his fallen workmate''.
* OddlyNamedSequel2ElectricBoogaloo: Lampshaded by the second film's opening theme song, referring to it as a nuclear powered boogaloo.
* OurPresidentsAreDifferent: By the time of ''Return to Nuke 'Em High'', heavy metal god / Troma regular [[{{Music/Motorhead}} Lemmy Kilmister]] has been elected to the highest office in the land. He also continues to wear his trademark hat and jacket.
* TheQuincyPunk
* TitleDrop: In Class of Nuke'em High 2: Subhumanoid Meltdown.
* RevolversAreJustBetter: The [[HandCannon .44]] [[Film/DirtyHarry Magnum]] is the weapon of choice for the Cretins.
* [[SpikesOfVillainy Spikes Of Monsterdom]]: The nuclear mutant is covered in these.
* {{Understatement}}: (After the school has been reduced to rubble) "Tromaville high will be closed temporarily for our remodeling."