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->''Well, yeah, the only reason'' we'' know there was some guy holding fire dude's leash is because my dad's basically [[Literature/HarryPotter Dumbledore]]''.
-->--'''Tedd''', Webcomic/ElGoonishShive

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* It was explained by the author that N4-T3 (Nate) of ''BobAndGeorge'', the Yellow Demon that was converted into a good guy, was an Expy of a guy named Nate with similar glass that was going to be in the [[OrphanedSeries hand-drawn comic that was originally planned]].
* ''Webcomic/CreativeRelease'' gives us Etoile, who is a very explicit expy of [[Anime/NeonGenesisEvangelion Ikari Shinji]] (he's a pilot who protects his planet from alien attacks and has doubts about his motivations).
* Natasha Wing from ''Webcomic/ElectricWonderland'' became introduced after Peter Paltridge's disgust with ''Series/{{Chuck}}'' character Anna Wu playing a progressively smaller role compelled him to make his own Asian ActionGirl.
* Grace, of ''Webcomic/ElGoonishShive'', definitely has nothing in common with SquirrelGirl... [[http://www.egscomics.com/?date=2002-05-25 oops]]. On the other hand, "{{cat girl}}"-to-"[[PettingZooPeople squirrel]] girl" substitution doesn't leave many options anyway.
* Masked vigilante [[Webcomics/TheFan Maelstrom]] is not completely unlike a certain mascot of a [[Music/IronMaiden certain band]].
* Bro's rapping vetriloquist dummy Lil' Cal in ''Webcomic/{{Homestuck}}'' shares a large number of traits with Franklin from ''Series/ArrestedDevelopment'', one of Hussie's favourite shows.
** In Act 6, we meet the Alpha kids, [[spoiler: aka alternate universe counterparts of the original kid's guardians, ]] who share some similarities to the [[spoiler: dead ]]trolls. Jane Crocker shares many similarities to [[GenkiGirl Feferi]] [[spoiler: and is related to her by adoption]], Jake English has similarities to [[BoisterousBruiser Equius]], Roxy is an odd mix of [[PlayfulHacker Sollux]], [[TheAlcoholic Gamzee]], and [[CatGirl Nepeta]], and Dirk is Equius and Rose.
** Given that Lord English, in both name and [[LordBritishPostulate properties]], is (at first unintentionally, but later [[AscendedFanon canonically]]) similar to [[NighInvulnerable Lord British]] of ''Main/{{Ultima}}'', it seems that his servant [[spoiler: [[MonsterClown Gamzee]]'s]] miraculous inability to die in all timelines, despite such extreme injuries as [[{{Determinator}} taking dozens of Caliborn's bullets in the chest]], makes him an expy of Chuckles.
* Lindesfarne from ''KevinAndKell'' fulfills a very similar role to that of Samantha from ''SafeHavens'': a kind, witty and intelligent scientist. Both were created by Bill Holbrook.
* ''TheLawOfPurple'' has several characters who are explicitly expies of ''Anime/YuGiOh'' characters: Lette, who is Seto Kaiba with boobs and a sense of humor, Juni, who is based on Alister, and Carli/y/eigh, who is Zigfried von Schroeder.
* ''WebComic/MagickChicks'' has several among its cast, most notably human renditions of [[WesternAnimation/MyLittlePonyFriendshipIsMagic "the Bronies".]]
** [[http://www.magickchicks.com/strips-mc/say_uncle! Rain and AJ]] are Rainbow Dash and Apple Jack respectively and have similar personality traits. The same is true of [[http://www.magickchicks.com/strips-mc/en_garde! Chastity]], who stands in for Rarity, Fluttershy [[http://www.magickchicks.com/strips-mc/a_flashy_spell is Skye]], and [[http://www.magickchicks.com/strips-mc/the_student_body Rosie]] is Pinkie Pie.
** There's also Tiffany Winters, who is [[{{parody}} a parody]] of [[Series/BuffyTheVampireSlayer Buffy Summers]]. While [[http://www.magickchicks.com/strips-mc/slipped_past_our_defenses Tandy]] is based on [[VisualNovel/FateStayNight Rin Tohsaka]], right down to being a mega twin-tailed {{tsundere}} and a Class S ZettaiRyouki (when she's in uniform).
* In-universe case in ''Webcomic/MegaTokyo''. Kotone, the IllGirl Kimiko is voicing in a game, is an expy of [[spoiler:Tohya Miho]], just like all other in-universe {{Ill Girl}}s. [[spoiler:Miho's story touched the world so much that it became more real than she ever was. One of the side effects of this is that she created the IllGirl trope as writers tried to capture the emotion of her story. The other is that it brought her back to life to relieve her sickness and die again. And again and again and again...]]
* The characters of MikeBookseller all work at a stand in for Barnes & Noble called Booksellers. Another bookstore (standing in for the now extinct Borders chain) appeared in the comic by the name of Booktraders.
* ''Webcomic/SurvivorFanCharacters'', being based on the reality TV show, sometimes bases its characters on real-life ''Survivor'' contestants. Some of the most obvious examples are Season 3's Baxter having a dynamic patterned after the "ManipulativeBastard angers the jury too much to win" one like Boston Rob from ''All-Stars'', and Season 7's Ventious having the leadership and charisma of Tom of ''Palau'' or J.T. from ''Tocantins'' (but ''not'' the FlawlessVictory) and Ker from the same season being a lovable eccentric who ended up immunitying her way to the win much like Fabio's in ''Nicaragua''.
* Olivia, Tate, and Zoey from ''{{Weesh}}'' are rather obviously modeled on Alex, Riley, and Tristan from the author's earlier ''Webcomic/AngelMoxie''. (Zoey is a teenager and Tate is a [[GenderFlip boy]], but other than that...)
* Every major character in ''{{Webcomic/Sire}}'' shares the basic story and abilities of their relevant Sire/Dam, though they are unique characters to themselves. So far characters descended from Literature/TheInvisibleMan, Literature/JeevesAndWooster, Literature/LesMiserables, Literature/ThePhantomOfTheOpera, Literature/TheStrangeCaseOfDrJekyllAndMrHyde and [[SweeneyTodd The String of Pearls]] have appeared.