* Mages in ''Webcomic/{{Chirault}}'' accidentally created a RealityChangingMiniature of their planet while trying to find a solution to an environmental problem. Then someone accidentally touched it. [[ApocalypseHow Good-bye, random city]].
* ''Webcomic/EightBitTheater'':
** [[http://www.nuklearpower.com/2004/06/17/episode-430-very-long-range/ Black Mage finally gets into a strong position]] [[WithFriendsLikeThese to kill his hated allies]], as he has attempted many times before. To assure his success, he aimed his KameHameHadoken not at them, but at the volcano they're standing on, which he plans would cause it to erupt and kill absolutely everything in the local and not-so-local vicinity. But, as the universe's ButtMonkey, [[CriticalFailure he fails]]. How does he fail? He misses. He misses an ''entire freaking mountain''. He misses anything on the entire planet and ends up '''killing the dinosaurs'''.
-->'''Thief:''' Not that I'm complaining about it, but...''[[color:red: HOW DO YOU '''MISS''' A VOLCANO?!]]''
** Earlier, when they were captured, BM tried to kill his allies. It was in a small corridor, easy to hit them in, with reflecting walls. What happened? He hit something: himself. It was the same attack as the volcano.
--->"How did you not only manage to miss us, but also hit yourself?"
** Due to Red Mage's unfailing belief the world works like a TabletopRPG, this occasionally comes up for him, [[http://www.nuklearpower.com/2001/11/21/episode-097-heroes-gathered/ too]].
--->'''Black Mage:''' You pushed Red Mage [...] Onto Fighter's sword.\\
'''Fighter:''' Which is weird because it started out sheathed.\\
'''Red Mage:''' I botched my Athletic Roll...Big time...
** Most of the things Fighter does qualify as well.
--->'''Fighter:''' When you gotta do somethin' wrong, [[http://www.nuklearpower.com/2004/09/30/episode-464-victory-for-some-doom-for-others/ you gotta do it right]]!
** King Steve loses his kingdom [[http://www.nuklearpower.com/2007/03/06/episode-816-cornerian-hold-em/ in a card game against Rodney]], a coffee stain and his imaginary right-hand man. That's not the Epic Fail, because King Steve is bug-nuts crazy. The true Epic Fail comes when Gary, his perfectly sane "left-hand man," [[http://www.nuklearpower.com/2007/03/08/episode-817-pravokan-pazaak/ offers to play cards with him after hearing the story]], and all "three" players lose the kingdom ''[[http://www.nuklearpower.com/2007/03/10/episode-818-harmful-if-swallowed/ to a piece of string]]''.
-->'''Sarah:''' And it was eligible in the first place because...?
-->'''Gary:''' Well, we needed a fourth.
** One time Fighter lost a game of Drownball. He spent several minutes underwater wearing heavy armor, yet...
-->'''Fighter:''' I did a thing where I didn't drown.
** Then there are [[http://www.nuklearpower.com/2002/04/08/episode-136-double-black-belt-trouble/ both]] of Black Belt's [[http://www.nuklearpower.com/2003/07/03/episode-303-in-case-you-were-wondering-about-them/ memorable]] attempts to find the bathroom.
** With all these examples, it's pretty safe to say that ''Webcomic/EightBitTheater'' could alternatively be titled ''Epic Failure: The Webcomic''.
* Aaron Williams' ''FullFrontalNerdity'' has, among other delightful slices of Gamer Life and other nerd instances, the occasional example of truly epic fail, almost always by Lewis. Though he is usually a victim of his own impulses and poor planning, he is also cursed with truly awful dice luck. [[http://ffn.nodwick.com/?p=388 This]] is a decent example of how bad Lewis can roll. He has also jinxed a die so badly it infected other d20 with the "1" virus, rolled a "1" when it was buried, and started making "1" show up everywhere. Further, Williams even has a collection of Nerdity out titled the ''Big Book of Epic Fail''.
** In the newer strip Lewis try to achieve godhood through demonstration of his miraculous [[http://ffn.nodwick.com/?p=1254 bad luck]].
* From ''JohnnyWander'': What do [[http://www.johnnywander.com/comics/62 trying to roast garlic]] and [[http://www.johnnywander.com/comics/50 drying peppers]] in the oven have in common besides the obvious? This. They even [[LampshadeHanging refer to the second incident]] as making homemade mace.
* Matt from ''Webcomic/MurphysLaw'' did this on his Test of Hidden Traps.
* In the first book of ''{{Goblins}}'', Fumbles fumbles a to-hit roll spectacularly. He trips, sends his spears flying into a lantern, which sets a hut on fire, which sets a bird on fire, and said bird retaliates by gouging the hell out of Fumbles' head.
-->'''Forgath:''' I just wanna know what kind of fumble chart he's using, so I could avoid it.
* In a non-canon ProblemSleuth [[http://www.mspaintadventures.com/extras/ps000020.html donation page,]] Team Sleuth strikes back at the Midnight Crew with the insanely powerful Catenative Doomsday Dice Cascader, a weapon that calculates damage by rolling a die for result ''X'', and filling the remaining popomatic bubbles with additional ''X''-sided dice. This is repeated until all dice are rolled, with the final die determining damage. The final result? '''One.''' Out of '''''50 trillion.'''''
* In ''Webcomic/{{Freefall}}'', [[http://freefall.purrsia.com/ff500/fv00425.htm Florence attempts]] ObfuscatingStupidity.
** Helix managed to blow out a bulkhead on the spacecraft he and Sam use. While making microwave popcorn, no less.
* Stef Murky of ''UserFriendly'' is absolutely ''awful'' at video games. He once fell in the lava in ''VideoGame/NeverwinterNights'' (something not possible without modding the game) and also once fell in the lava at the ''startup screen'' of ''VideoGame/QuakeII''.
* In ''WapsiSquare'', Tina describes a previous time [[http://wapsisquare.com/comic/parallel-parking/ she had to run the coffee shop with an arm in a cast.]] [[NoodleIncident Somehow]] she managed to back over her wrist while trying to [[ParallelParking parallel park.]]
* Cleo from ''{{Bobwhite}}'' discusses this. While her dad tries to teach her how to fold clothes, [[http://www.bobwhitecomics.com/?webcomic_post=20090902 Cleo talks about]] how funny it would be if her terrible clothes-folding skills accidentally set her clothes on fire.
* ''Webcomic/TheOrderOfTheStick'':
** Thog failed his will save against a Zone of Truth spell (which normally only prevents telling lies) so badly that he started spouting every truth he knew, resulting in several TooMuchInformation moments.
** Whenever Elan fails a Move Silently Check, he [[WithCatlikeTread announces his failure by shouting]].
** In the prequel book ''On the Origin of [=PCs=], the party epically fails in its very first round of combat as a unified party, against a group of kobolds. We see the characters' thoughts as they prepare actions: [[ASimplePlan Haley prepares an action to attack the first creature that charges, Elan prepares an action to flank attack the first wounded creature, and Vaarsuvius prepares an action to Lightning Bolt the first 4 creatures that line up toward hir]]. Belkar starts by charging a kobold (he misses his attack). Haley attacks him (as he was the first to charge) and hits; Elan flanks him and attacks (as Belkar was the first to be wounded); and V promptly nukes all 3 and the kobold with a Lightning Bolt (as they were lined up).
--->'''Durkon:''' On tha plus side, I think tha other kobolds died from laughter.
** The image for FailedASpotCheck is their most exceptional example of this failure.
* Batman CaptainErsatz [[PosthumousCharacter Beeman]] is introduced via flashback in ''Webcomic/TheAdventuresOfDrMcNinja'' trying to foil a bank robbery. He flips into the air as the bandits open fire on him and... [[http://drmcninja.com/archives/comic/9p16/ soon falls dead]].
* The Ho'aku tribe in ''SurvivorFanCharacters'' was truly an epic fail, filled with a) weak and easily influenced members, b) jealous and power-hungry contestants who wanted to lead and voted out the first two leaders, and c) [[CanonImmigrant Russell Hantz]], who sabotaged their tribe. What happened was one of the worst losing streaks in the comic's history, with the Ho'aku tribe losing ten out of thirteen challenges, going to every single Tribal Council but one, and ultimately being whittled down to two members. [[spoiler: However, the tribe's plight is spectacularly subverted when a member of the Ho'aku tribe manages to go on an immunity run and win the game!]]
** Cherman from Season 9 was an epic fail in ''all'' challenges, in spite of being a robot specifically programmed to be the ultimate Survivor bot. [[spoiler:Then it's similarly subverted at the very end when he ''wins'' the entire game.]]
* [[Webcomic/SequentialArt Art, how can you screw up]] [[http://www.collectedcurios.com/sequentialart.php?s=378 pancake flipping SO BAD?]]
* In ''WebComic/LsEmpire'', [[ButtMonkey Void]] shows that it's possible to [[http://l-empire.smackjeeves.com/comics/1296232/games-of-life-pt-13/ miss a shot a point blank range.]]
* SaturdayMorningBreakfastCereal features [[http://www.smbc-comics.com/?db=comics&id=277#comic this]] lovely spoon-accident.
* ''Webcomic/{{xkcd}}'':
** An attempt to install [=OpenBSD=] can lead to a [[http://xkcd.com/349/ shark attack]].
** Failing to properly throw a boomerang is one thing. Failing so hard you [[http://xkcd.com/445/ make your girlfriend leave you]] or [[http://xkcd.com/475/ break the ozone layer]] is something else.
* In ''Webcomic/{{Homestuck}}'', a certain unwise action in [[spoiler:the Kids' session]] lead to consequences so staggering they rendered [[spoiler:''someone else's session of the game'' {{unwinnable}}]].
** And then it turns out that [[spoiler:it was someone in the ''other'' session who rendered ''both'' sessions {{unwinnable}}]]... by [[spoiler:''giving a universe cancer'']]. Fails don't get much more epic than that.[[note]] Of course, because the StableTimeLoop required them to fail, so in this case, [[FailureIsTheOnlyOption Epic Failure Is The Only Option]].[[/note]]
** Eridan's entire session in the Land of Wrath and Angels was wasted due to his determination to kill the friendly yet formidable angels until he finally turns them all against him. Everyone he complains to about it figures out that they aren't the enemies, but he continues to whine about its unfairness long after the game is over.
* There's a ton of examples from ''Webcomic/VGCats''. In one comic, Leo (who is Altair from Assassin's Creed) tries to pick his nose, only to stab himself in the face with the hidden blade.
* ''Webcomic/SomethingPositive'':
** Kharisma tries to take a geek trivia test. Davan grades it: "Just so you know, Literature/TheLastUnicorn was not, in fact, [[Franchise/StarWars Luke's father]]."
** Earlier, Aubrey makes a TV show. When it's broadcast, the State of Massachusetts imposes a restraining order on her to keep her away from any TV or film-making equipment in the future.
* In ''WebComic/CommanderKitty'', when CK and crew are trying to [[http://www.commanderkitty.com/2009/11/14/could-this-be-the-end/ test their transporter on Mittens]], they somehow manage to [[http://www.commanderkitty.com/2009/11/22/if-a-panda-is-traveling-at-120-kph/ teleport the entire transporter out of the ship instead]].
* ''WebComic/FinalFantasyVIITheSevening'': Without materia, Cloud can't even enter a house properly. Instead he somehow winds up getting knocked over and pinned down by several cats. Even he doesn't know how it happened.
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