* [[http://xninjared.deviantart.com/art/Cho-reads-My-Immortal-152293752 This]] is the usual response someone gets when they've read ''Fanfic/MyImmortal''.
* Lexx from ''AlienDice'' tried to kill himself several times but survived because of tiny machines injected into his circulation. He doesn't dare to try the most radical methods for fear of the pain if the machines would still repair his body. Only after several attempts to die failed did he gather the determination to try and win.
* Justin from ''Webcomic/ElGoonishShive'' seriously contemplated suicide a few years ago (in comic time). ''BigBad'' Damien actually committed suicide upon realizing he was [[AGodAmI not a god]].
* Luna Travoria from ''Webcomic/DominicDeegan'' tried to kill herself twice in the same story arc. The first attempt ended with [[spoiler:Luna and Dominic uncovering a plot from her crazy mother, in which she would make a great deal of money by Luna driven to suicide. The old lady would wind up dead anyway, after picking a fight with a Royal Knight and getting her head chopped off.]] The second time, Luna [[spoiler:jumped off a bridge after said crazy mother left her nothing in her will, and her half-dead body was discovered by Dominic and his cat Spark while on a fishing trip.]]
** Nimmel Feenix later tries the jumping-off-a-bridge strategy for himself after a rather horrific attack on his class by a PsychoForHire. He's stopped by none other than Luna herself.
* Two characters from ''YuMeDream'' feel DrivenToSuicide.
* One of the Paladins in ''Webcomic/TheOrderOfTheStick'' [[http://www.giantitp.com/comics/oots0448.html commits seppuku after a slaughter in the throneroom]]
* ''QuestionableContent'' has Faye, a girl with obvious issues. It is later revealed that the reason she is so severely messed up is that [[spoiler:her father, who she saw as her best friend and in whom she confided everything, committed suicide for reasons unknown by blowing his brains out with a gun, ''in front of her''. He went outside in the early morning without realizing that she had gotten out of bed and followed him outside. Then he blew his brains out before she could call out to him. Yikes.]]
** It's also implied that the car accident she was in just before the story started was an attempt. Faye says that she isn't sure herself, because she doesn't remember the moments leading up to the crash.
* Scotty kills himself in ''SomethingPositive''.
* ''Breakfast of the Gods'': [[spoiler:Trix]] tries to hang himself after [[spoiler:betraying Cap'n Crunch into a fatal ambush]]. He doesn't succeed, because the tree cuts him off and says [[spoiler:[[BlackComedy "Silly rabbit."]]]]
* Artie Crowley of ''{{Concession}}'' was seen holding a gun to his head after realising [[spoiler:he had had sex with a prepubescent boy while in a trance and unable to realise what he was doing]], but he didn't go through with it.
* This is the entire basis for every storyline in ''SuicideForHire'', which is ExactlyWhatItSaysOnTheTin.
* [[TheWoobie ApenShephard]] of ''Webcomic/TheSilverEye'' lost his will to live and tried to take his own life when he was only ten years old after being exiled from his country, and a number of other tragic events.
* After untolds amounts of emotional suffering due to his robotic form, the [[TheWoobie title character]] of ''Webcomic/WarbotInAccounting'' finally decides to kill himself by jumping off his office building while leaving behind a note scribbled "No Love". It doesn't work due to him being NighInvulnerable and he ends up taking crap from his co-workers for skipping work.
* BLU Sniper in ''Webcomic/CuantaVida'', after [[spoiler: losing both his lover and his eyes. Because he was blinded, though, [[MercyKill Medic had to help him.]]]]
** [[spoiler: Or so the BLU Medic ''claims''; subsequent events suggest another possibility.]]
* ''Webcomic/OtterSoldiers'': Subverted. One of the characters at one point contemplates upon committing suicide. She ends up thinking too much about how it could end up going horribly wrong (survived but crippled etc.), and is ultimately unable to go through with it.
* Neilli of ''{{Juathuur}}'' is driven to suicide [[spoiler: by Meidar, who decides that a girl that wants to be a healer would make a perfect torturer. Possibly a SecretTestOfCharacter directed at Neilli's boyfriend Thomil.]]
* Daichi Takana's mother is apparently driven to suicide by a Mafia boss, who just so happens to be his friend's father in [[http://mitadakesaga.webcomic.ws/comics/9 The Mitadake Saga]]
* Conor from ''FreakAngels'' shoots himself in the head, not out of a true desire to die, but out of a wish to upgrade his mental abilities. His action fits this trope because he really didn't know whether he'd survive, and his conversation with Arkady and relationship with the other Freak Angels suggest that he didn't much care.
* At the end of ''AndersLovesMaria'', [[spoiler: Tina]] commits suicide after [[spoiler: failing to win Anders back.]]
* ''WapsiSquare'' BackStory: Jin tried to derail the spell with this. [[SenselessSacrifice It didn't work]]
* ''Webcomic/{{Bug|Martini}}'' sees this as [[http://www.bugcomic.com/comics/website-woes/ an acceptable response when your web server goes down.]]
* [[spoiler:[[BittersweetCandyBowl Lucy]] does this in "Disaster Dominoes" near the end to [[TogetherInDeath join the recently run down Mike.]]]]
* A RunningGag across ''MSPaintAdventures'' as a whole is people being driven to suicide near a stump in an empty field, later named the Land of Stumps and Dismay in ''Webcomic/{{Homestuck}}''. First it was the protagonist of ''Webcomic/{{Jailbreak}}'', then later an ''audience member'' of ''Webcomic/ProblemSleuth'' and ''Homestuck'' gives it some serious consideration in response to events in the comics themselves.
** However, a few of the characters have attempted suicide: the Ace Dick who played the Game of Life with Death in ProblemSleuth, and the Handmaid in {{Homestuck}}. Both cases proved temporary, although the Handmaid eventually succeeded in SuicideByCop.
* In ''Webcomic/MonsieurCharlatan'', [[http://monsieur-charlatan.com/archive/page-1/ Charlatan is contemplating in the opening scene.]]
* In ''Webcomic/{{Pacificators}}'', [[TheDitz Larima]] [[GenkiGirl Torbern]] is implied to be this. She recklessly uses her power ''all the time,'' which only makes her burn herself out much faster (as people with powers [[BlessedWithSuck shorten their lifespan if they use their power excessively]]), and she shows slight DeathSeeker tendencies, such as placing herself in the path of danger ''for no reason at all.''
** [[spoiler:This makes sense, however, when one consider that Larima's little sister Taffe is deaf, and [[DisabilitySuperpower uses her power of air to hear]], which means Taffe is burning herself out in a much quicker pace - and ''will'' die before Larima does. Throw in the fact that [[DeathByOriginStory their parents are dead]], and we may have the reason to Larima's attitude - [[TearJerker she doesn't want to live without her little sister. She doesn't want to be alone. She's trying to pace herself with Taffe]].]]