Take a drink for every time...
* Homura attempts to save Madoka.
* Chug the glass when [[spoiler: Mami gets eaten.]]
* Drink when a named Witch (Gertrud, Charlotte, Walpurgisnacht...) shows up.
* When runes show up onscreen.
** 2 drinks if you know what the runes say.
** 3 drinks if you didn't have to look it up beforehand.
* The words 'wish' or 'contract' are mentioned.
* Kyubey tries to coerce Madoka into becoming a magical girl.
** 2 drinks when he talks about her potential as a magical girl.
* Madoka or Sayaka contemplate what they should wish for.
* Kyubey gets injured.
* A Madoka Magica-related meme pops up (such as [[spoiler:Mami's beheading]]).
* Homura [[spoiler: resets the timeline.]]
* Homura [[HairFlip flips her hair]].
* There is LesYay.
* Someone mentions Kyubey's [[spoiler: 'cruelty'.]]
* Take a sip every time a soul gem is onscreen.
** Down the glass if the soul gem is black or nearly black.
* Take a gulp every time the phrase 'precious friend' is mentioned.
* There's a flashback.
** Hell, just down 2 glasses for episode 10.
* A witch's world is shown.
* Kyouko and Sayaka fight.
* Madoka starts crying.
* [[BigEater Kyouko]] eats something.
* "Being meguca" is demonstrated to "be suffering".
* You want to punch Kyubey.
** Note: If you get so drunk that you actually punch the screen, Kyubey wins.
In the Dub:
* Every time Sayaka says, "For realz?"