When you play the [[IncrediblyLamePun Drinking Game of Thrones]], you win, or your liver dies. There is no middle ground:

* Whenever the name of one of the four main houses is said (Stark, Lannister, Baratheon, or Targaryen) is said, you drink.
** Alternatively, assign players to a house, with each player only drinking when their house name is said.
** House Greyjoy can be added in Season 2, Tyrell for Season 3 and Martell for Season 4.
** Although not a house, the Night's Watch can be used as well.
* Each player also chooses a religion: the Faith of the Seven or the Old Gods. When their religion is mentioned, they drink.
** Starting with Season 2, add the Drowned God and the Lord of Light R'hllor to the list.
* Whenever someone dies, drink. If they're a major character, finish your drink.
** If they are an AssholeVictim, [[AndThereWasMuchRejoicing pop a fresh bottle of champagne after the show.]] [[spoiler: [[Awesome/GameOfThrones Recommended for Season 4. Take that Joff!]] ]]
*** Note: Do not attempt this for "[[Recap/GameOfThronesS4E4Oathkeeper Oathkeeper]]", tempting it may be. [[spoiler: [[KarmicDeath One cannot afford a hundred and sixty three bottles of champagne.]] ]]%% Technically those aren't "major characters." It's still tempting, though.
* Whenever there is [[NudityTropes nudity]], drink.
** Be sure your affairs are in order because this will kill you.
* Whenever a character ([[TheAlcoholic probably Robert, Tyrion and Cersei from Season 2 onwards]]) on screen drinks, drink.

A few extra challenges if you feel brave:

* Whenever a character is addressed as ''milord/lady'', take a sip. Take two for ''your grace''. WARNING: [[RunningGag This will kill you.]]
* Whenever Hodor says "Hodor", drink. [[RuleOfThree Warning: This will kill you.]]
* Whenever Joffery is a [[KickTheDog dick]], drink.
* Whenever someone mentions the White Walkers, drink. Down your drink if the White Walkers or a Wight actually makes a physical appearance.[[note]]That last bit isn't part of the game; [[NightmareFuel/GameOfThrones it's to help with the fear.]][[/note]]
* Whenever somebody says "Winter is coming", take a drink.
* Whenever the word whore is used, take a drink.
* Whenever Tyrion insults someone, take a drink.
* Whenever someone says "The Night Is Dark and Full of Terrors", take a drink.
* Whenever Ygritte says "[[PhraseCatcher You know nothing, Jon Snow.]]", take a drink.
** Down the entire bottle [[spoiler: [[Recap/GameOfThronesS4E9TheWatchersOnTheWall when she says it for the last time.]] ]]
* Whenever Jaqen H'ghar says "a man" or "a girl", take a drink.
* Whenever someone addresses Jon as "bastard", take a drink.
** If they say "you must be Ned Stark's bastard" during their first meeting, take two drinks.
* Whenever someone refers to "The King in the North", take a drink. Finish the drink [[ChewingTheScenery if the phrase is immediately echoed by someone.]]
* Whenever Varys [[AsYouKnow mentions]] he's a Eunuch, take a drink.
** Or whenever Littlefinger mentions Varys's testicles and lack thereof.
* Whenever Jorah says ''Khaleesi'', take a drink.
** [[AllLoveIsUnrequited Whenever he gets pushed further into the friendzone]], take another drink.
*** After he finally calls her "Daenerys" and [[spoiler: gets flat-out rejected and cast out]] in [[spoiler: [[Recap/GameOfThronesS4E8TheMountainAndTheViper 4x08]] ]], down the whole bottle.
* Whenever Roose or [[spoiler: Ramsay Bolton]] troll someone, take a drink. In fact, take a drink every time you see them or a member of House Bolton (this includes soldiers and Locke).
* Whenever Tywin does something awesome, take a drink. Take two drinks if he's a dick to [[TheUnfavourite Tyrion]] in the same scene.
* Whenever the Rains of Castamere is played or sung, take a drink.
** Take three gulps if something terrible happens afterwards.
* For Seasons 2 and 3: Take a drink every time Robb Stark makes a potentially devastating or bad move to his overall character arc.
* Take a drink everytime Edmure Tully makes a witty remark. Take two drinks if the Blackfish reprimands him immediately afterwards.
* Drink whenever something horrible or heartbreaking happens to Sansa. For extra difficulty, do the same whenever the same happens to Tyrion post Season 2.
* Down a whole jar of [[GargleBlaster 140 proof moonshine]] [[DidYouActuallyBelieve if you were under the blissful impression that there were no]] {{Evil Overlord}}s [[DidYouActuallyBelieve in Westeros]], [[LowFantasy just sleazy politicking humans and disorganized monsters]], [[spoiler: [[TheUnexpected but, bam,]] '''[[{{HSQ}} the Night's King appears.]]''' ]]
** [[spoiler: [[NotHisSled This means you too,]] ''[[NotHisSled Bookwalkers.]]'' ]]
* Take a shot when [[CoolOldLady Olenna Tyrell]] does something awesome. Have another if she insults someone in the process.
* Every time [[spoiler: Ramsay [[InsistentTerminology Bolton]]]] and [[spoiler: Reek]] engage in NoYay, take a shot.
* For book readers, take two shots whenever the show deviates from the books. [[AdaptationDistillation For better or]] [[AdaptationDecay for worse.]]
* Have a drink whenever a character dismisses everyone from a room, servants, protection or other royality, minus the one or two people they want for a heart to heart discussion.

Alternatively...

* [[DrowningMySorrows Just down the whole bottle before]] [[WhamEpisode episode nine]] [[AnyoneCanDie of every season.]]
** [[OverlyLongGag WARNING:]] [[BrickJoke This will kill you.]]

When your liver is dead it may never die, but rises again harder and stronger.