* ''Webcomic/RealLifeComics'' suffered from a form of Creator Breakdown twice, both times when Greg Dean broke up with his then-current girlfriends. Rather than affect the quality of the series, though, he simply took a brief hiatus from the comic (as he didn't feel like working on it at the time) and returned a week or so later and picked up where he left off, with the ex-girlfriend's character [[PutOnABus vanishing without a trace and never mentioned again]]. Of course, Greg has since gotten married, so these mini-breakdowns may be a thing of the past.
** One strip does playfully lampshade it, however; Greg and Tony are visiting multiple dimensions and they stumble across the OffstageWaitingRoom where Crystal (the first ex-girlfriend) is playing cards with Danny ([[OutOfFocus a friend who gradually faded out of the strip]]). Crystal looks up and says, "What, did the Artist get bored with you, too?"
* In 2002, ''Ubersoft.net'' took two-and-a-half months out from an ongoing plotline to inflict the author's computer woes on one of the main characters.
** A similar story is behind the ''Webcomic/BobTheAngryFlower'' strip ''My Computer Is A Monster'', in which Bob's computer unplugs itself, grows to the size of a small house and rampages through the streets eating people.
* While the official explanation for why ''Webcomic/RPGWorld'' was canceled is due to ArtistDisillusionment, the fact that the main arc just suddenly ended without any noticeable decline in quality during the ostensible final storyline, along with a couple post-script side stories that basically curb-stomped the characters, seems less like actual burnout and more like some event really turned the author against his work.
* Parodied (and very possibly played straight) with ''Webcomic/{{Homestuck}}'', dealing with AndrewHussie's massive ego.
** [[DiscussedTrope Andrew has stated very clearly on his Formspring]] that [[AvertedTrope none of the random self-insert gags or darker twists in the story arise from any sort of stress or ego on his behalf]], and [[TakeThat criticized his fanbase]] for assuming that the story becoming darker could only be because of a creator breakdown, and not just because it's how he wanted the story to progress. It was averted again later, where Andrew announced he would take longer between updates, allowing him to relax and prevent any future chances of Creator Breakdown. The fanbase hasn't stopped from insisting that FanDumb is going to cause this soon.
** With Act 5 over, Act 6 seems to have hit a reset button on everyone's pent up emotions. Ironically in hindsight it seems that while Hussie was fine, the ''fans'' degenerated into angry fitiful infighting and constant drama, reaching MemeticMutation levels with "Hiatusstuck", shorthand for the amazingly weird stuff the fanbase came up with during hiatuses.
* Parodied in a brief ''Webcomic/BobAndGeorge'' storyline, in which the [[AuthorGuestSpot author character]] becomes extremely depressed, causing the strip to ''literally'' start to fall apart, with panels sliding off each other, becoming disoriented, and appearances by characters who are supposed to be elsewhere. Naturally, the problem is solved with explosives.
* RealLife seems to have been playing BreakTheCutie with Maritza Campos, author of ''Webcomic/CollegeRoomiesFromHell'', slowly but surely, since 1999. [[CerebusSyndrome It shows.]]
* ''Webcomic/{{Doobl}}'' was a short-lived comic that started as a Christian evangelical comic and became eventually more and more dark when the author's mother died, finishing in killing off every character and then the author himself. It was later made official that it was a StealthParody, but man, it'd be easy to get fooled.
* Anne Onymous, pseudonymous creator of ''Webcomic/TheWotch'' took a hiatus when her marriage abruptly ended but came back and soldiered on for nearly a year before petering out again without much explanation, citing unspecified "avoidance issues."
* ''Webcomic/BrawlInTheFamily'' creator Matthew Taranto suffered a short case of Creator Breakdown when his Wii was gutted out and lost all of its data. He drew a bonus strip where all of the major cast members [[EndOftheWorldasWeKnowIt as well as the Earth itself]] were destroyed by the Sun, as a comedic reference to a previous bonus comic.
** Another example was the time he spent in the hospital dealing with his Crohn's Disease, though the effect of that was less "weird stuff happens in the comic as a result" and more "the comic doesn't get updated as a result".
* The webcomic ''Webcomic/{{Avalon}}'' unfortunately suffered from this more and more as the author went through progressively worse states of depression not long after being launched. The planned four-year series lasted much longer due to month-long hiatuses. After a year of not-updating, the author gave up and the ending was written out instead of drawn.
* ''Webcomic/LivingWithInsanity'' was originally supposed to be a solo comic done by David Herbert, updating every weekday (And sometimes on weekends) successfully. However, despite there only being thirty strips, David was repeatedly told by friends and pro editors that while they enjoyed his writing, his art was horrible. To make matters worse, his girlfriend dumped him around this time. His already frail ego shattered, Herbert quit the comic's art duties and hired Paul Salvi, which ended up making the comic much more successful than any of Herbert's other comics.
* Sean Howard has claimed the reason ''Webcomic/AModestDestiny'' has been on hiatus for over a year is he is no longer deep enough into Creator Breakdown to follow coherently from where he left off.
* The author of ''Webcomic/GameDestroyers'' reached a point in the story where he grew to hate what he was writing, which led to two of the four [[SeriesHiatus hiatuses]] and a lot of ScheduleSlip. This was eventually solved by getting past the horrible storyline and moving on to things which made more sense and allowed for more freedom.
* Ever since Randall Munroe's fiance was diagnosed with breast cancer, ''Webcomic/{{xkcd}}'' has featured several strips dealing with cancer, ranging from BlackComedy to not comedy.
* Teased but averted in-universe in ''Webcomic/DarthsAndDroids'' (a retelling of the ''Franchise/StarWars'' movies as a tabletop RPG). Jim and Annie (playing Padme and Anakin respectively - [[CrossPlayer we know, we know]], things just turned out that way) started Episode III with their relationship having gone sour, and with Annie really enjoying the roleplaying aspect it looked like a breakup would prompt her to make Anakin have a FaceHeelTurn and kill Jim's character in revenge. What acutally ultimately happened was that they reconciled; Padme still died but this was Jim actually roleplaying for once, using the death scene to give Annie more angsty material to work with.
* John Kossler, author of ''Webcomic/TheWordWeary'', has no problem admitting that his entire comic is a way to cope with his depression humorously.
* Christian Weston Chandler, creator of ''Webcomic/{{Sonichu}}'', does this in issue 10 of his series, [[KillEmAll eradicating everything that has bothered Chris up to that point]]. After that, he unofficially [[OrphanedSeries abandoned the comic]], claiming that the trolls "[[http://www.youtube.com/watch?v=KAqAIkE1ZIs drained his creativity]]".
** A little more backstory to this: A lot of Chris' breakdown was due to the fact that his Internet {{Troll}}s wanted to show him the reality of him wanting to officially produce his comic. Major cases of ScheduleSlip, Chris fighting with a fan who didn't want him to use a character he made for shits and giggles, having [[Webcomic/{{Asperchu}} a rival webcomic]] being more popular than his, all culminating when it interfered with his real life and angrily deriding his fans as those who'd just want more of his comics than him having a life. Which isn't much, but that's a different story altogether.
* Lis Boriss of ''Webcomic/BrokenPlotDevice'' fame had her mother diagnosed with breast cancer. Lis's depression caused an unexpected indefinite hiatus, but luckily, surgery was succesfull, and webcomic came back very quickly.
** Now her relationship of eight years has collapsed (though it appears to be ending amicably), and the strip is on hiatus again. The biggest problem seems to be how to deal with Sid, who is strongly based on her now ex-boyfriend.
* This was one of the most popular theories about Tess Stone and her jarringly abrupt [[OrphanedSeries abandonment]] of her series ''Webcomic/HannaIsNotABoysName''.
* Jeph Jacques of ''Webcomic/QuestionableContent'' has had issues with depression and anxiety in the past, which have on occasion caused him to take a day or two off from drawing the normal strip. However, in 2012, he stabbed his hand in a drunken stupor and took two weeks off from his comic after a tumblr user sent him an angry and belligerent post over one of his latest comics. What did he do? He didn't draw HollywoodHomely nerd Marigold [[RantInducingSlight "fat enough" in a swimsuit]].
* Nicholas Gurewitch of ''ComicStrip/ThePerryBibleFellowship'' suffered a breakdown in 2008 when he put the comic on indefinite hiatus out of fear that becoming too dedicated to it would [[TypeCasting forever pigeonhole his career as only a webcomics artist]]. For some time, the final strip appearing on the site was "Catch Phrase", a rather [[BlackComedy dark]] and [[DoesThisRemindYouOfAnything poignant]] comic (even by PBF standards) in which a TV personality commits suicide after [[CreatorBacklash becoming sick of the over-saturated popularity]] of his catchphrase, "Gee Golly Jeepers!" PBF would not return until over two years later, upon which Gurewitch began updating the comic again, albeit much less frequently than before. The "Catch Phrase" strip has since been removed from the official website but can be seen [[http://www.funnyjunk.com/funny_pictures/94973/Catchphrase/ here]].
* Michael Poe, the writer/artist for ''Webcomic/ErrantStory'', has been having a long run of bad luck for the last couple of years, culminating in his hospitalization in February 2013. Between his health problems and his wife's, it's hard not to wonder if there's some kind of ancient curse involved.
* ''Webcomic/HyperboleAndAHalf'' has suffered majorly from this, putting the comic on semi-permanent hiatus while the writer battles depression.
* The author of ''Webcomic/PicturesForSadChildren'' is right in the middle of one. After removing all comics from his website right around the time he started a Kickstarter to publish them in book form, he eventually exceeded his goal, but then suddenly he made a rambling Kickstarter post stating that he won't be giving out any more of the rewards backers earned, and calling out his backers for expecting something in return for their investment (which he'd promised from the beginning) and basically saying that he shouldn't have to do anything in return for payment. Along with the post was [[https://www.kickstarter.com/projects/73258510/sad-pictures-for-children/posts/759318 a video of him burning a Pictures For Sad Children book for every email he received about said rewards]], and threatening to burn even more for every e-mail he got afterwards.
* A purely physical variation affected the creator of ''Webcomic/ParadigmShift''; he pushed himself a bit too hard and ended up with a pinched nerve. A long hiatus ensued while he underwent physiotherapy, and updates have been sporadic ever since.

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